Incidental Mutation 'IGL02231:Zfp936'
ID 285719
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Zfp936
Ensembl Gene ENSMUSG00000064194
Gene Name zinc finger protein 936
Synonyms EG435970, Gm9272, I1C0022H11Rik
Accession Numbers
Is this an essential gene? Possibly essential (E-score: 0.727) question?
Stock # IGL02231
Quality Score
Status
Chromosome 7
Chromosomal Location 43114229-43192109 bp(+) (GRCm38)
Type of Mutation splice site
DNA Base Change (assembly) T to A at 43187485 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000145999 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000072829] [ENSMUST00000072829] [ENSMUST00000200973] [ENSMUST00000200973] [ENSMUST00000202535] [ENSMUST00000205912]
AlphaFold Q3ULA8
Predicted Effect probably null
Transcript: ENSMUST00000072829
SMART Domains Protein: ENSMUSP00000072608
Gene: ENSMUSG00000064194

DomainStartEndE-ValueType
KRAB 3 65 5.32e-19 SMART
ZnF_C2H2 148 170 5.9e-3 SMART
ZnF_C2H2 176 198 5.9e-3 SMART
ZnF_C2H2 204 226 1.4e-4 SMART
ZnF_C2H2 232 254 1.2e-3 SMART
ZnF_C2H2 260 282 7.37e-4 SMART
ZnF_C2H2 288 310 2.27e-4 SMART
ZnF_C2H2 316 338 2.09e-3 SMART
ZnF_C2H2 344 366 1.45e-2 SMART
ZnF_C2H2 372 394 1.82e-3 SMART
ZnF_C2H2 400 422 2.53e-2 SMART
ZnF_C2H2 428 450 4.54e-4 SMART
Predicted Effect probably null
Transcript: ENSMUST00000072829
SMART Domains Protein: ENSMUSP00000072608
Gene: ENSMUSG00000064194

DomainStartEndE-ValueType
KRAB 3 65 5.32e-19 SMART
ZnF_C2H2 148 170 5.9e-3 SMART
ZnF_C2H2 176 198 5.9e-3 SMART
ZnF_C2H2 204 226 1.4e-4 SMART
ZnF_C2H2 232 254 1.2e-3 SMART
ZnF_C2H2 260 282 7.37e-4 SMART
ZnF_C2H2 288 310 2.27e-4 SMART
ZnF_C2H2 316 338 2.09e-3 SMART
ZnF_C2H2 344 366 1.45e-2 SMART
ZnF_C2H2 372 394 1.82e-3 SMART
ZnF_C2H2 400 422 2.53e-2 SMART
ZnF_C2H2 428 450 4.54e-4 SMART
Predicted Effect probably null
Transcript: ENSMUST00000200973
SMART Domains Protein: ENSMUSP00000144191
Gene: ENSMUSG00000064194

DomainStartEndE-ValueType
KRAB 4 66 1.4e-21 SMART
Predicted Effect probably null
Transcript: ENSMUST00000200973
SMART Domains Protein: ENSMUSP00000144191
Gene: ENSMUSG00000064194

DomainStartEndE-ValueType
KRAB 4 66 1.4e-21 SMART
Predicted Effect probably null
Transcript: ENSMUST00000202535
SMART Domains Protein: ENSMUSP00000143800
Gene: ENSMUSG00000064194

DomainStartEndE-ValueType
KRAB 4 66 2.3e-21 SMART
ZnF_C2H2 149 171 2.6e-5 SMART
ZnF_C2H2 177 199 2.5e-5 SMART
ZnF_C2H2 205 227 5.9e-7 SMART
ZnF_C2H2 233 255 5.1e-6 SMART
ZnF_C2H2 261 283 3.1e-6 SMART
ZnF_C2H2 289 311 9.4e-7 SMART
ZnF_C2H2 317 339 8.7e-6 SMART
ZnF_C2H2 345 367 6.3e-5 SMART
ZnF_C2H2 373 395 7.7e-6 SMART
ZnF_C2H2 401 423 1.1e-4 SMART
ZnF_C2H2 429 451 2e-6 SMART
Predicted Effect probably null
Transcript: ENSMUST00000205912
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 48 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2610507B11Rik G A 11: 78,279,896 G1647D probably benign Het
Alcam T A 16: 52,274,050 probably benign Het
Alox15 A C 11: 70,349,556 D266E probably benign Het
Atcay A T 10: 81,210,548 V314E probably damaging Het
Atp8b1 C T 18: 64,550,384 G758R possibly damaging Het
Cacna2d4 T A 6: 119,277,908 probably benign Het
Celsr3 T C 9: 108,842,510 V2429A probably damaging Het
Clspn T G 4: 126,559,228 D11E probably damaging Het
Cnot3 A G 7: 3,658,210 T573A probably benign Het
Cyp2d34 A T 15: 82,618,606 S140T probably benign Het
Edem1 A G 6: 108,828,888 D50G probably benign Het
Emilin3 G A 2: 160,908,515 T438I probably damaging Het
Etfdh C T 3: 79,618,393 V173I probably damaging Het
Fat2 T C 11: 55,281,092 T2932A probably damaging Het
Fcrl1 G A 3: 87,385,162 E154K possibly damaging Het
Fcrl1 A T 3: 87,385,163 E154V probably damaging Het
G3bp1 T A 11: 55,495,447 L244* probably null Het
Itgae A T 11: 73,090,622 K2M possibly damaging Het
Kcnq2 T C 2: 181,081,715 I654V probably benign Het
Ksr2 C T 5: 117,500,776 R82C probably damaging Het
Lrig3 A T 10: 125,997,172 D305V probably damaging Het
Me1 T C 9: 86,611,855 K322E possibly damaging Het
Med12l T A 3: 59,245,882 D1109E probably damaging Het
Mest A G 6: 30,740,773 K73E possibly damaging Het
Nup155 T G 15: 8,144,064 L881R probably damaging Het
Ocln A T 13: 100,541,114 S2T probably damaging Het
Oosp3 T C 19: 11,699,439 L54S probably damaging Het
Pkp3 G A 7: 141,084,238 E443K probably damaging Het
Plk2 T A 13: 110,400,069 C632S probably benign Het
Ptk6 C T 2: 181,197,001 V320I probably damaging Het
Ptprt A T 2: 162,238,060 I273N probably damaging Het
Ptprt A G 2: 162,278,046 probably null Het
Rab3gap2 T C 1: 185,266,898 probably benign Het
Rabgef1 G A 5: 130,211,975 A312T probably damaging Het
Rabl6 T A 2: 25,598,184 K109N probably benign Het
Rbp7 C T 4: 149,454,877 probably null Het
Reg3a C T 6: 78,382,241 H75Y possibly damaging Het
Rnf123 G T 9: 108,066,399 P546T probably benign Het
Rnmt C A 18: 68,314,081 C345* probably null Het
Ror2 C T 13: 53,110,728 S764N probably damaging Het
Slc14a2 C T 18: 78,209,021 S25N possibly damaging Het
Spata16 G T 3: 26,913,264 G388W probably damaging Het
Speg C T 1: 75,423,387 R2493W probably damaging Het
Thada T A 17: 84,428,697 D970V probably damaging Het
Tmem184c A G 8: 77,604,812 Y103H probably damaging Het
Ttn A T 2: 76,798,096 D12827E probably damaging Het
Utp20 A G 10: 88,791,168 L976S probably damaging Het
Zfp318 C T 17: 46,396,810 R265* probably null Het
Other mutations in Zfp936
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02245:Zfp936 APN 7 43187298 critical splice donor site probably null
IGL02335:Zfp936 APN 7 43187267 missense probably damaging 1.00
FR4340:Zfp936 UTSW 7 43189489 missense possibly damaging 0.63
R0437:Zfp936 UTSW 7 43189310 missense probably benign 0.00
R3899:Zfp936 UTSW 7 43189734 missense possibly damaging 0.93
R4120:Zfp936 UTSW 7 43190206 missense probably benign 0.10
R4406:Zfp936 UTSW 7 43190324 missense possibly damaging 0.82
R4959:Zfp936 UTSW 7 43189610 missense probably damaging 1.00
R5023:Zfp936 UTSW 7 43187257 missense probably damaging 1.00
R5163:Zfp936 UTSW 7 43190240 missense probably damaging 1.00
R5182:Zfp936 UTSW 7 43189907 missense probably damaging 1.00
R5292:Zfp936 UTSW 7 43189335 nonsense probably null
R5668:Zfp936 UTSW 7 43190434 missense possibly damaging 0.93
R6057:Zfp936 UTSW 7 43190363 missense probably benign 0.00
R6901:Zfp936 UTSW 7 43190043 missense probably damaging 1.00
R7139:Zfp936 UTSW 7 43190291 missense possibly damaging 0.54
R7258:Zfp936 UTSW 7 43190379 missense probably damaging 1.00
R7440:Zfp936 UTSW 7 43187261 missense probably damaging 1.00
R7537:Zfp936 UTSW 7 43189815 nonsense probably null
R7561:Zfp936 UTSW 7 43189915 missense probably damaging 0.98
R7662:Zfp936 UTSW 7 43189912 nonsense probably null
R7775:Zfp936 UTSW 7 43190296 missense possibly damaging 0.70
R7778:Zfp936 UTSW 7 43190296 missense possibly damaging 0.70
R8016:Zfp936 UTSW 7 43189424 missense possibly damaging 0.61
R8121:Zfp936 UTSW 7 43190123 missense possibly damaging 0.55
R9012:Zfp936 UTSW 7 43189992 nonsense probably null
R9058:Zfp936 UTSW 7 43189772 missense probably benign 0.32
R9188:Zfp936 UTSW 7 43190344 missense probably benign 0.00
R9236:Zfp936 UTSW 7 43187498 missense probably benign 0.00
R9596:Zfp936 UTSW 7 43190410 missense probably damaging 1.00
Posted On 2015-04-16