Incidental Mutation 'IGL02236:Zfp13'
| ID |
285897 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Zfp13
|
| Ensembl Gene |
ENSMUSG00000062012 |
| Gene Name |
zinc finger protein 13 |
| Synonyms |
Krox-8, Zfp-13 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.126)
|
| Stock # |
IGL02236
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
17 |
| Chromosomal Location |
23794818-23818461 bp(-) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
A to T
at 23799739 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000154342
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000057029]
[ENSMUST00000115516]
[ENSMUST00000227952]
|
| AlphaFold |
P10754 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000057029
|
| SMART Domains |
Protein: ENSMUSP00000054595
Gene: ENSMUSG00000062012
| Domain | Start | End | E-Value | Type |
|---|
|
KRAB
|
117 |
179 |
7.54e-10 |
SMART |
|
ZnF_C2H2
|
259 |
281 |
7.37e-4 |
SMART |
|
ZnF_C2H2
|
287 |
309 |
1.2e-3 |
SMART |
|
ZnF_C2H2
|
315 |
337 |
5.9e-3 |
SMART |
|
ZnF_C2H2
|
343 |
365 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
371 |
393 |
9.73e-4 |
SMART |
|
ZnF_C2H2
|
399 |
421 |
2.12e-4 |
SMART |
|
ZnF_C2H2
|
427 |
449 |
1.18e-2 |
SMART |
|
ZnF_C2H2
|
455 |
477 |
6.52e-5 |
SMART |
|
low complexity region
|
480 |
503 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000115516
|
| SMART Domains |
Protein: ENSMUSP00000111178
Gene: ENSMUSG00000062012
| Domain | Start | End | E-Value | Type |
|---|
|
KRAB
|
124 |
186 |
7.54e-10 |
SMART |
|
ZnF_C2H2
|
266 |
288 |
7.37e-4 |
SMART |
|
ZnF_C2H2
|
294 |
316 |
1.2e-3 |
SMART |
|
ZnF_C2H2
|
322 |
344 |
5.9e-3 |
SMART |
|
ZnF_C2H2
|
350 |
372 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
378 |
400 |
9.73e-4 |
SMART |
|
ZnF_C2H2
|
406 |
428 |
2.12e-4 |
SMART |
|
ZnF_C2H2
|
434 |
456 |
1.18e-2 |
SMART |
|
ZnF_C2H2
|
462 |
484 |
6.52e-5 |
SMART |
|
low complexity region
|
487 |
510 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000227952
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000228298
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000228942
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 31 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Baz1b |
T |
C |
5: 135,246,138 (GRCm39) |
L529P |
probably damaging |
Het |
| Bdp1 |
A |
T |
13: 100,197,399 (GRCm39) |
D995E |
probably benign |
Het |
| Cd22 |
T |
C |
7: 30,566,893 (GRCm39) |
N607S |
possibly damaging |
Het |
| Ddx10 |
T |
A |
9: 53,146,682 (GRCm39) |
D180V |
probably damaging |
Het |
| Dennd4c |
T |
C |
4: 86,725,672 (GRCm39) |
Y709H |
possibly damaging |
Het |
| Dhrs3 |
A |
C |
4: 144,620,133 (GRCm39) |
I17L |
probably benign |
Het |
| Dnah8 |
A |
T |
17: 30,868,747 (GRCm39) |
K394* |
probably null |
Het |
| Flnc |
T |
A |
6: 29,454,375 (GRCm39) |
I1896N |
probably damaging |
Het |
| Glipr1l2 |
A |
G |
10: 111,928,534 (GRCm39) |
Y143C |
probably damaging |
Het |
| Lmo7 |
T |
C |
14: 102,163,524 (GRCm39) |
|
probably benign |
Het |
| Lpp |
C |
T |
16: 24,580,895 (GRCm39) |
R204W |
probably damaging |
Het |
| Mast3 |
A |
G |
8: 71,241,888 (GRCm39) |
S98P |
probably benign |
Het |
| Myf5 |
A |
G |
10: 107,320,051 (GRCm39) |
S200P |
possibly damaging |
Het |
| Or52r1b |
T |
G |
7: 102,690,928 (GRCm39) |
S76A |
possibly damaging |
Het |
| Pramel12 |
G |
A |
4: 143,143,512 (GRCm39) |
V93I |
probably benign |
Het |
| Recql5 |
A |
C |
11: 115,784,856 (GRCm39) |
S824A |
probably benign |
Het |
| Reg2 |
A |
G |
6: 78,383,188 (GRCm39) |
E45G |
probably damaging |
Het |
| Rergl |
T |
C |
6: 139,471,918 (GRCm39) |
D77G |
probably benign |
Het |
| Rnf224 |
T |
C |
2: 25,126,260 (GRCm39) |
D31G |
probably damaging |
Het |
| Sema4c |
C |
T |
1: 36,592,166 (GRCm39) |
S227N |
probably damaging |
Het |
| Sgsm2 |
C |
T |
11: 74,750,698 (GRCm39) |
G439D |
probably damaging |
Het |
| Smap2 |
T |
A |
4: 120,832,587 (GRCm39) |
M185L |
probably benign |
Het |
| Spty2d1 |
A |
G |
7: 46,647,360 (GRCm39) |
V523A |
probably benign |
Het |
| Stk17b |
C |
A |
1: 53,803,247 (GRCm39) |
R184L |
probably damaging |
Het |
| Syt13 |
A |
G |
2: 92,771,210 (GRCm39) |
D99G |
probably damaging |
Het |
| Trav14-1 |
T |
A |
14: 53,791,763 (GRCm39) |
S38T |
possibly damaging |
Het |
| Ttn |
T |
C |
2: 76,700,812 (GRCm39) |
|
probably benign |
Het |
| Usp17la |
G |
A |
7: 104,510,353 (GRCm39) |
W319* |
probably null |
Het |
| Vmn2r73 |
T |
C |
7: 85,521,902 (GRCm39) |
T146A |
probably benign |
Het |
| Vwa3b |
C |
T |
1: 37,193,132 (GRCm39) |
|
probably benign |
Het |
| Zscan18 |
A |
C |
7: 12,503,251 (GRCm39) |
D769E |
probably benign |
Het |
|
| Other mutations in Zfp13 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL02447:Zfp13
|
APN |
17 |
23,795,072 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02449:Zfp13
|
APN |
17 |
23,795,072 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02450:Zfp13
|
APN |
17 |
23,795,072 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02466:Zfp13
|
APN |
17 |
23,795,072 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02468:Zfp13
|
APN |
17 |
23,795,072 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02471:Zfp13
|
APN |
17 |
23,795,072 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02473:Zfp13
|
APN |
17 |
23,795,072 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02474:Zfp13
|
APN |
17 |
23,795,072 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02475:Zfp13
|
APN |
17 |
23,795,072 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02491:Zfp13
|
APN |
17 |
23,795,072 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02511:Zfp13
|
APN |
17 |
23,795,072 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02558:Zfp13
|
APN |
17 |
23,795,072 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL03030:Zfp13
|
APN |
17 |
23,799,819 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03388:Zfp13
|
APN |
17 |
23,795,888 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0053:Zfp13
|
UTSW |
17 |
23,795,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0053:Zfp13
|
UTSW |
17 |
23,795,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1514:Zfp13
|
UTSW |
17 |
23,795,386 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2420:Zfp13
|
UTSW |
17 |
23,795,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3433:Zfp13
|
UTSW |
17 |
23,795,602 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4458:Zfp13
|
UTSW |
17 |
23,800,150 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4650:Zfp13
|
UTSW |
17 |
23,799,112 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4824:Zfp13
|
UTSW |
17 |
23,795,797 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5088:Zfp13
|
UTSW |
17 |
23,796,035 (GRCm39) |
nonsense |
probably null |
|
|
R5110:Zfp13
|
UTSW |
17 |
23,799,834 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5384:Zfp13
|
UTSW |
17 |
23,800,156 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7302:Zfp13
|
UTSW |
17 |
23,800,036 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8443:Zfp13
|
UTSW |
17 |
23,795,866 (GRCm39) |
missense |
probably benign |
|
|
R9728:Zfp13
|
UTSW |
17 |
23,799,788 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
| Posted On |
2015-04-16 |
Incidental Mutation