Incidental Mutation 'IGL00959:Gm11437'
ID28599
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm11437
Ensembl Gene ENSMUSG00000051452
Gene Namepredicted gene 11437
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.121) question?
Stock #IGL00959
Quality Score
Status
Chromosome11
Chromosomal Location84148351-84167476 bp(-) (GRCm38)
Type of Mutationintron
DNA Base Change (assembly) A to C at 84148622 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000116174 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000050771] [ENSMUST00000133811]
Predicted Effect probably benign
Transcript: ENSMUST00000050771
SMART Domains Protein: ENSMUSP00000056084
Gene: ENSMUSG00000051452

DomainStartEndE-ValueType
Pfam:DUF4711 1 226 7.4e-102 PFAM
low complexity region 227 238 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000133811
SMART Domains Protein: ENSMUSP00000116174
Gene: ENSMUSG00000020532

DomainStartEndE-ValueType
signal peptide 1 22 N/A INTRINSIC
PDB:2YL2|B 115 157 2e-21 PDB
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 37 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Alox12b A T 11: 69,166,243 H430L probably damaging Het
Aox4 G T 1: 58,239,174 V443F probably damaging Het
Bmpr2 A T 1: 59,815,315 I108F possibly damaging Het
Cflar G A 1: 58,729,162 probably null Het
Chchd3 A G 6: 32,968,253 V106A probably benign Het
Chl1 G T 6: 103,709,250 probably null Het
Clvs2 C T 10: 33,528,463 M252I probably benign Het
Cntnap5a T A 1: 116,184,327 L449Q probably benign Het
Col6a2 T A 10: 76,614,534 I188F probably damaging Het
Cyp2c55 A G 19: 39,038,143 D398G probably benign Het
Dennd1b T C 1: 139,143,888 probably benign Het
Dopey1 T A 9: 86,487,431 Y106N probably damaging Het
Dpy19l1 A T 9: 24,423,197 probably null Het
Extl3 C T 14: 65,076,912 V274I probably benign Het
Fras1 G A 5: 96,781,281 R3848H probably damaging Het
Gss T A 2: 155,581,951 D2V probably damaging Het
Hnrnpm C A 17: 33,649,902 R517L probably damaging Het
Ilvbl G A 10: 78,583,905 D548N probably damaging Het
Jmjd6 A T 11: 116,842,376 D115E possibly damaging Het
Kidins220 T A 12: 25,051,133 S1110R possibly damaging Het
Kmt2c T A 5: 25,276,229 I4784F probably damaging Het
Mrpl52 T C 14: 54,427,037 V11A possibly damaging Het
Myo3b A G 2: 70,314,292 Y1036C probably damaging Het
Olfr769 T A 10: 129,112,024 M134L probably benign Het
Omp T C 7: 98,145,150 D90G probably damaging Het
Osmr T C 15: 6,824,605 I541V probably benign Het
Ppp1r32 A T 19: 10,477,523 probably null Het
Ppp2r1a A T 17: 20,961,578 probably benign Het
Ptpn13 T A 5: 103,517,571 probably null Het
Rock2 C A 12: 16,978,055 N1429K probably benign Het
Slc25a20 T G 9: 108,681,999 M188R possibly damaging Het
Slc28a1 T C 7: 81,169,068 probably benign Het
Sult2a6 T C 7: 14,254,709 Y42C probably damaging Het
Tgfb2 A G 1: 186,704,587 V63A probably benign Het
Ugt2b38 A T 5: 87,411,823 N403K probably damaging Het
Vmn2r29 A G 7: 7,241,856 W340R probably benign Het
Wnt5a C T 14: 28,522,909 T351M probably damaging Het
Other mutations in Gm11437
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01354:Gm11437 APN 11 84167318 intron probably benign
IGL02051:Gm11437 APN 11 84152766 missense probably benign 0.00
IGL03184:Gm11437 APN 11 84156264 intron probably benign
R0076:Gm11437 UTSW 11 84148636 missense possibly damaging 0.91
R0076:Gm11437 UTSW 11 84148636 missense possibly damaging 0.91
R1241:Gm11437 UTSW 11 84164628 missense possibly damaging 0.93
R2135:Gm11437 UTSW 11 84153812 missense probably damaging 0.97
R4065:Gm11437 UTSW 11 84164511 missense probably benign 0.13
R4067:Gm11437 UTSW 11 84164511 missense probably benign 0.13
R5356:Gm11437 UTSW 11 84152687 missense possibly damaging 0.90
R6571:Gm11437 UTSW 11 84156212 missense probably benign 0.13
R6594:Gm11437 UTSW 11 84164560 missense probably null 0.03
R7173:Gm11437 UTSW 11 84164548 missense probably benign 0.39
R7368:Gm11437 UTSW 11 84167472 intron probably benign
X0026:Gm11437 UTSW 11 84165327 missense possibly damaging 0.92
X0028:Gm11437 UTSW 11 84156100 critical splice donor site probably null
Posted On2013-04-17