Incidental Mutation 'IGL02238:Krt88'
ID285993
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Krt88
Ensembl Gene ENSMUSG00000063971
Gene Namekeratin 88
Synonyms1700011A15Rik
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL02238
Quality Score
Status
Chromosome15
Chromosomal Location101447744-101453907 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) A to G at 101452605 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000023781 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000023781]
Predicted Effect probably benign
Transcript: ENSMUST00000023781
SMART Domains Protein: ENSMUSP00000023781
Gene: ENSMUSG00000063971

DomainStartEndE-ValueType
Pfam:Filament 1 109 5e-24 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 39 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abca15 T A 7: 120,396,606 I1322N probably benign Het
Adamts1 A T 16: 85,795,825 M565K probably benign Het
Akr1b7 T A 6: 34,415,398 Y49N probably damaging Het
Cacna2d2 T A 9: 107,513,558 V363E probably damaging Het
Cdc45 C T 16: 18,798,729 M200I probably benign Het
Cdh10 C T 15: 19,013,519 T735I probably damaging Het
Cds1 T A 5: 101,814,436 C306S possibly damaging Het
Clasp2 T C 9: 113,880,020 C644R probably damaging Het
Coil T C 11: 88,981,754 S314P probably benign Het
D630045J12Rik T A 6: 38,196,394 M280L probably benign Het
Dmxl2 C T 9: 54,445,433 V795M probably damaging Het
Dock10 A G 1: 80,533,793 V1533A probably damaging Het
Fbxo40 T C 16: 36,969,174 N525D possibly damaging Het
Fezf2 T C 14: 12,344,494 E231G probably damaging Het
Fmn1 T C 2: 113,582,125 V870A possibly damaging Het
Ifi44 A G 3: 151,732,382 *423Q probably null Het
Invs T C 4: 48,390,029 V173A probably damaging Het
Mctp2 A T 7: 72,090,205 Y812* probably null Het
Neto2 T C 8: 85,669,663 I118V probably damaging Het
Nutm2 T G 13: 50,471,039 M264R probably damaging Het
Olfr52 T C 2: 86,181,595 probably null Het
Olfr715 A G 7: 107,129,037 S119P probably damaging Het
Pcnx G A 12: 81,917,914 R285Q probably damaging Het
Pi16 G T 17: 29,326,295 K177N probably damaging Het
Pigg C T 5: 108,318,928 S225F possibly damaging Het
Prrc2b T A 2: 32,213,417 V969E probably damaging Het
Rab4b A C 7: 27,172,729 Y189D probably benign Het
Ran A G 5: 129,022,182 N143D possibly damaging Het
Rfc4 A T 16: 23,114,469 F286L probably damaging Het
Sel1l2 T C 2: 140,247,939 Y418C probably damaging Het
Slc13a1 T C 6: 24,103,483 I354V probably benign Het
Slc7a2 A T 8: 40,908,156 T386S probably benign Het
Tm2d2 G T 8: 25,022,771 V212F probably benign Het
Tmem247 A T 17: 86,918,293 N54Y probably damaging Het
Txnrd3 T A 6: 89,656,135 Y206N probably benign Het
Uba5 T C 9: 104,054,060 probably benign Het
Vmn2r54 A G 7: 12,635,983 L51P probably damaging Het
Wdr66 T C 5: 123,302,423 Y1091H probably damaging Het
Zfp735 A G 11: 73,710,493 K88E probably benign Het
Other mutations in Krt88
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01069:Krt88 APN 15 101453627 makesense probably null
R3916:Krt88 UTSW 15 101452928 splice site probably null
R3917:Krt88 UTSW 15 101452928 splice site probably null
R5161:Krt88 UTSW 15 101450468 missense probably benign 0.28
R7253:Krt88 UTSW 15 101450511 missense probably damaging 1.00
R7360:Krt88 UTSW 15 101447762 start gained probably benign
R8163:Krt88 UTSW 15 101453508 missense probably damaging 1.00
R8498:Krt88 UTSW 15 101453525 missense probably benign
R8745:Krt88 UTSW 15 101453579 missense possibly damaging 0.95
Posted On2015-04-16