Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02239:Zfp784'

285999

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Zfp784

Ensembl Gene

ENSMUSG00000043290

Gene Name

zinc finger protein 784

Synonyms

C730049F21Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.231) question?

Stock #

IGL02239

Quality Score

Status

Chromosome

Chromosomal Location

5037445-5041445 bp(-) (GRCm39)

Type of Mutation

intron

DNA Base Change (assembly)

T to C at 5038670 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000146978 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000062428] [ENSMUST00000076251] [ENSMUST00000076791] [ENSMUST00000085427] [ENSMUST00000207050] [ENSMUST00000208728]

AlphaFold

Q8BI69

Predicted Effect

unknown
Transcript: ENSMUST00000062428
AA Change: E296G

SMART Domains

Protein: ENSMUSP00000051979
Gene: ENSMUSG00000043290
AA Change: E296G

Domain	Start	End	E-Value	Type
low complexity region	8	24	N/A	INTRINSIC
ZnF_C2H2	64	86	1.02e1	SMART
ZnF_C2H2	100	122	9.96e-1	SMART
ZnF_C2H2	128	150	6.67e-2	SMART
low complexity region	180	192	N/A	INTRINSIC
ZnF_C2H2	195	217	4.11e-2	SMART
ZnF_C2H2	223	245	7.26e-3	SMART
ZnF_C2H2	251	273	3.21e-4	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000076251

SMART Domains

Protein: ENSMUSP00000075601
Gene: ENSMUSG00000074405

Domain	Start	End	E-Value	Type
low complexity region	6	20	N/A	INTRINSIC
low complexity region	62	82	N/A	INTRINSIC
low complexity region	120	141	N/A	INTRINSIC
low complexity region	171	193	N/A	INTRINSIC
ZnF_C2H2	220	242	1.28e-3	SMART
ZnF_C2H2	248	270	5.5e-3	SMART
low complexity region	274	286	N/A	INTRINSIC
low complexity region	294	324	N/A	INTRINSIC
ZnF_C2H2	350	372	8.81e-2	SMART
ZnF_C2H2	378	400	6.08e-5	SMART
ZnF_C2H2	407	429	1.79e-2	SMART
ZnF_C2H2	439	461	1.92e-2	SMART
low complexity region	478	495	N/A	INTRINSIC
low complexity region	502	516	N/A	INTRINSIC
low complexity region	523	542	N/A	INTRINSIC
ZnF_C2H2	546	568	4.47e-3	SMART
ZnF_C2H2	574	596	5.42e-2	SMART
ZnF_C2H2	602	624	1.72e-4	SMART
low complexity region	628	660	N/A	INTRINSIC
ZnF_C2H2	664	686	5.34e-1	SMART
ZnF_C2H2	692	714	2.82e0	SMART
low complexity region	725	745	N/A	INTRINSIC
low complexity region	750	770	N/A	INTRINSIC
low complexity region	772	788	N/A	INTRINSIC
ZnF_C2H2	791	813	1.64e-1	SMART
ZnF_C2H2	819	841	9.3e-1	SMART
ZnF_C2H2	847	869	2.95e-3	SMART
ZnF_C2H2	875	897	3.83e-2	SMART
ZnF_C2H2	903	925	2.05e-2	SMART
ZnF_C2H2	931	953	1.18e-2	SMART
ZnF_C2H2	959	981	1.36e-2	SMART
ZnF_C2H2	988	1010	5.06e-2	SMART
ZnF_C2H2	1016	1038	4.72e-2	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000076791

Predicted Effect

probably benign
Transcript: ENSMUST00000085427

SMART Domains

Protein: ENSMUSP00000082550
Gene: ENSMUSG00000074405

Domain	Start	End	E-Value	Type
low complexity region	6	20	N/A	INTRINSIC
low complexity region	62	82	N/A	INTRINSIC
low complexity region	120	141	N/A	INTRINSIC
low complexity region	171	193	N/A	INTRINSIC
ZnF_C2H2	220	242	1.28e-3	SMART
ZnF_C2H2	248	270	5.5e-3	SMART
low complexity region	274	286	N/A	INTRINSIC
low complexity region	294	324	N/A	INTRINSIC
ZnF_C2H2	350	372	8.81e-2	SMART
ZnF_C2H2	378	400	6.08e-5	SMART
ZnF_C2H2	407	429	1.79e-2	SMART
ZnF_C2H2	439	461	1.92e-2	SMART
low complexity region	478	495	N/A	INTRINSIC
low complexity region	502	516	N/A	INTRINSIC
low complexity region	523	542	N/A	INTRINSIC
ZnF_C2H2	546	568	4.47e-3	SMART
ZnF_C2H2	574	596	5.42e-2	SMART
ZnF_C2H2	602	624	1.72e-4	SMART
low complexity region	628	660	N/A	INTRINSIC
ZnF_C2H2	664	686	5.34e-1	SMART
ZnF_C2H2	692	714	2.82e0	SMART
low complexity region	725	745	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000207050

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000207193

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000207362

Predicted Effect

probably benign
Transcript: ENSMUST00000208728

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 29 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcf3	A	G	16: 20,369,386 (GRCm39)	E262G	possibly damaging	Het
Adgra3	T	A	5: 50,118,054 (GRCm39)	S1165C	probably damaging	Het
Akap11	A	G	14: 78,751,289 (GRCm39)	L366P	probably damaging	Het
Astn1	T	C	1: 158,491,700 (GRCm39)		probably null	Het
Bhmt2	C	T	13: 93,799,687 (GRCm39)	G250R	probably benign	Het
Cdc45	C	T	16: 18,617,479 (GRCm39)	M200I	probably benign	Het
Cntnap2	A	G	6: 46,998,588 (GRCm39)	D880G	probably damaging	Het
Erc1	A	G	6: 119,750,852 (GRCm39)	V443A	probably damaging	Het
Fbxw15	A	G	9: 109,388,905 (GRCm39)	I168T	probably benign	Het
Fgfr2	C	T	7: 129,779,416 (GRCm39)	A504T	probably damaging	Het
Galm	A	G	17: 80,452,467 (GRCm39)	D135G	probably damaging	Het
Gstp3	C	T	19: 4,107,899 (GRCm39)	V145I	possibly damaging	Het
Hspa5	T	C	2: 34,662,788 (GRCm39)	F115L	probably benign	Het
Lig4	A	C	8: 10,022,473 (GRCm39)	S436A	probably damaging	Het
Ncam1	A	G	9: 49,478,702 (GRCm39)	V99A	probably damaging	Het
Nell1	T	A	7: 49,899,398 (GRCm39)	I336N	probably benign	Het
Or52ad1	T	C	7: 102,995,805 (GRCm39)	Y110C	probably damaging	Het
Or5p55	T	C	7: 107,567,254 (GRCm39)	S217P	probably damaging	Het
Or8g20	T	A	9: 39,395,857 (GRCm39)	I231F	probably damaging	Het
Patl1	A	T	19: 11,914,723 (GRCm39)	K625*	probably null	Het
Qrsl1	G	A	10: 43,770,596 (GRCm39)	P99S	possibly damaging	Het
Rfx8	T	C	1: 39,720,046 (GRCm39)	D343G	probably benign	Het
Scart2	T	C	7: 139,875,756 (GRCm39)	F340S	probably damaging	Het
Serpinb3a	T	A	1: 106,979,418 (GRCm39)	Y28F	probably benign	Het
Slc6a4	A	T	11: 76,917,982 (GRCm39)	I575F	probably benign	Het
Tbx5	T	A	5: 120,009,345 (GRCm39)	S285T	possibly damaging	Het
Tmem229a	A	T	6: 24,955,539 (GRCm39)	S72T	probably damaging	Het
Ttn	T	C	2: 76,576,748 (GRCm39)	D24715G	probably damaging	Het
Zswim2	T	A	2: 83,769,107 (GRCm39)	K85*	probably null	Het

Other mutations in Zfp784

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01516:Zfp784	APN	7	5,039,036 (GRCm39)	intron	probably benign
IGL03333:Zfp784	APN	7	5,039,351 (GRCm39)	intron	probably benign
R1464:Zfp784	UTSW	7	5,038,800 (GRCm39)	missense	possibly damaging	0.71
R1464:Zfp784	UTSW	7	5,038,800 (GRCm39)	missense	possibly damaging	0.71
R1515:Zfp784	UTSW	7	5,039,039 (GRCm39)	intron	probably benign
R1604:Zfp784	UTSW	7	5,039,453 (GRCm39)	intron	probably benign
R1606:Zfp784	UTSW	7	5,038,774 (GRCm39)	missense	possibly damaging	0.85
R1723:Zfp784	UTSW	7	5,038,782 (GRCm39)	missense	possibly damaging	0.71
R2428:Zfp784	UTSW	7	5,041,357 (GRCm39)	intron	probably benign
R2680:Zfp784	UTSW	7	5,039,116 (GRCm39)	missense	possibly damaging	0.86
R8083:Zfp784	UTSW	7	5,038,905 (GRCm39)	missense	possibly damaging	0.53
R8143:Zfp784	UTSW	7	5,038,910 (GRCm39)	missense	possibly damaging	0.93
R9382:Zfp784	UTSW	7	5,041,338 (GRCm39)	missense	unknown

Posted On

2015-04-16