Incidental Mutation 'IGL02240:Gad1-ps'
ID |
286029 |
Institutional Source |
Australian Phenomics Network
(link to record)
|
Gene Symbol |
Gad1-ps
|
Ensembl Gene |
ENSMUSG00000090665 |
Gene Name |
glutamate decarboxylase 1, pseudogene |
Synonyms |
Gad-1ps |
Accession Numbers |
|
Essential gene? |
Probably non essential
(E-score: 0.208)
|
Stock # |
IGL02240
|
Quality Score |
|
Status
|
|
Chromosome |
10 |
Chromosomal Location |
99279906-99281681 bp(+) (GRCm39) |
Type of Mutation |
exon |
DNA Base Change (assembly) |
A to G
at 99280820 bp (GRCm39)
|
Zygosity |
Heterozygous |
Amino Acid Change |
|
Gene Model |
predicted gene model for transcript(s):
|
AlphaFold |
no structure available at present |
Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000167243
|
SMART Domains |
Protein: ENSMUSP00000133048 Gene: ENSMUSG00000090665
Domain | Start | End | E-Value | Type |
Pfam:Pyridoxal_deC
|
1 |
368 |
4.3e-153 |
PFAM |
Pfam:Beta_elim_lyase
|
91 |
436 |
7.3e-8 |
PFAM |
Pfam:Aminotran_5
|
130 |
370 |
4.7e-7 |
PFAM |
|
Coding Region Coverage |
|
Validation Efficiency |
|
Allele List at MGI |
|
Other mutations in this stock |
Total: 22 list
Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
Cand2 |
A |
G |
6: 115,780,623 (GRCm39) |
E1169G |
probably damaging |
Het |
Cdc34 |
A |
G |
10: 79,523,823 (GRCm39) |
D168G |
possibly damaging |
Het |
Cwc27 |
A |
T |
13: 104,943,151 (GRCm39) |
F130L |
probably damaging |
Het |
Dglucy |
T |
A |
12: 100,837,672 (GRCm39) |
M635K |
possibly damaging |
Het |
Eral1 |
G |
A |
11: 77,968,687 (GRCm39) |
R149* |
probably null |
Het |
Glis3 |
A |
T |
19: 28,508,925 (GRCm39) |
L353Q |
probably damaging |
Het |
Gsta2 |
T |
A |
9: 78,238,441 (GRCm39) |
I213F |
probably benign |
Het |
Ist1 |
A |
T |
8: 110,408,836 (GRCm39) |
|
probably benign |
Het |
Kif1b |
A |
G |
4: 149,330,871 (GRCm39) |
V549A |
probably damaging |
Het |
Lrp2 |
C |
T |
2: 69,365,390 (GRCm39) |
R261H |
probably benign |
Het |
Msh4 |
T |
C |
3: 153,579,311 (GRCm39) |
N512S |
probably damaging |
Het |
Nlrp2 |
A |
T |
7: 5,330,822 (GRCm39) |
S525T |
probably damaging |
Het |
Nlrp4a |
G |
T |
7: 26,148,703 (GRCm39) |
K103N |
possibly damaging |
Het |
Or8b56 |
T |
A |
9: 38,739,602 (GRCm39) |
V205D |
probably benign |
Het |
Pcdhb10 |
A |
T |
18: 37,545,455 (GRCm39) |
H177L |
possibly damaging |
Het |
Plcb3 |
A |
T |
19: 6,935,448 (GRCm39) |
|
probably benign |
Het |
Podxl |
A |
G |
6: 31,501,933 (GRCm39) |
L342P |
probably damaging |
Het |
Psd4 |
T |
G |
2: 24,286,389 (GRCm39) |
S330A |
probably benign |
Het |
Sucla2 |
A |
G |
14: 73,828,287 (GRCm39) |
D298G |
probably damaging |
Het |
Tecr |
T |
C |
8: 84,300,045 (GRCm39) |
D107G |
probably damaging |
Het |
Vamp4 |
T |
A |
1: 162,405,446 (GRCm39) |
N24K |
possibly damaging |
Het |
Zfp91 |
A |
G |
19: 12,753,770 (GRCm39) |
|
probably benign |
Het |
|
Other mutations in Gad1-ps |
Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
IGL00963:Gad1-ps
|
APN |
10 |
99,281,310 (GRCm39) |
exon |
noncoding transcript |
|
IGL01301:Gad1-ps
|
APN |
10 |
99,281,013 (GRCm39) |
exon |
noncoding transcript |
|
IGL01394:Gad1-ps
|
APN |
10 |
99,281,424 (GRCm39) |
exon |
noncoding transcript |
|
IGL02220:Gad1-ps
|
APN |
10 |
99,281,184 (GRCm39) |
exon |
noncoding transcript |
|
IGL03406:Gad1-ps
|
APN |
10 |
99,280,641 (GRCm39) |
exon |
noncoding transcript |
|
ANU18:Gad1-ps
|
UTSW |
10 |
99,281,013 (GRCm39) |
exon |
noncoding transcript |
|
R0305:Gad1-ps
|
UTSW |
10 |
99,280,665 (GRCm39) |
exon |
noncoding transcript |
|
R0446:Gad1-ps
|
UTSW |
10 |
99,281,383 (GRCm39) |
exon |
noncoding transcript |
|
R0538:Gad1-ps
|
UTSW |
10 |
99,280,854 (GRCm39) |
exon |
noncoding transcript |
|
R1511:Gad1-ps
|
UTSW |
10 |
99,281,331 (GRCm39) |
exon |
noncoding transcript |
|
R1734:Gad1-ps
|
UTSW |
10 |
99,281,637 (GRCm39) |
exon |
noncoding transcript |
|
R1745:Gad1-ps
|
UTSW |
10 |
99,281,386 (GRCm39) |
exon |
noncoding transcript |
|
R1886:Gad1-ps
|
UTSW |
10 |
99,281,444 (GRCm39) |
exon |
noncoding transcript |
|
R3111:Gad1-ps
|
UTSW |
10 |
99,280,383 (GRCm39) |
exon |
noncoding transcript |
|
R3617:Gad1-ps
|
UTSW |
10 |
99,281,260 (GRCm39) |
exon |
noncoding transcript |
|
R5042:Gad1-ps
|
UTSW |
10 |
99,281,516 (GRCm39) |
exon |
noncoding transcript |
|
R5223:Gad1-ps
|
UTSW |
10 |
99,281,009 (GRCm39) |
exon |
noncoding transcript |
|
R5234:Gad1-ps
|
UTSW |
10 |
99,281,188 (GRCm39) |
exon |
noncoding transcript |
|
R5275:Gad1-ps
|
UTSW |
10 |
99,280,751 (GRCm39) |
exon |
noncoding transcript |
|
R5295:Gad1-ps
|
UTSW |
10 |
99,280,751 (GRCm39) |
exon |
noncoding transcript |
|
R5334:Gad1-ps
|
UTSW |
10 |
99,281,009 (GRCm39) |
exon |
noncoding transcript |
|
R5335:Gad1-ps
|
UTSW |
10 |
99,281,009 (GRCm39) |
exon |
noncoding transcript |
|
R5336:Gad1-ps
|
UTSW |
10 |
99,281,009 (GRCm39) |
exon |
noncoding transcript |
|
R5337:Gad1-ps
|
UTSW |
10 |
99,281,009 (GRCm39) |
exon |
noncoding transcript |
|
R5396:Gad1-ps
|
UTSW |
10 |
99,281,009 (GRCm39) |
exon |
noncoding transcript |
|
R5397:Gad1-ps
|
UTSW |
10 |
99,281,009 (GRCm39) |
exon |
noncoding transcript |
|
R5399:Gad1-ps
|
UTSW |
10 |
99,281,009 (GRCm39) |
exon |
noncoding transcript |
|
R5428:Gad1-ps
|
UTSW |
10 |
99,281,009 (GRCm39) |
exon |
noncoding transcript |
|
R5429:Gad1-ps
|
UTSW |
10 |
99,281,009 (GRCm39) |
exon |
noncoding transcript |
|
R5431:Gad1-ps
|
UTSW |
10 |
99,281,009 (GRCm39) |
exon |
noncoding transcript |
|
R5661:Gad1-ps
|
UTSW |
10 |
99,280,901 (GRCm39) |
exon |
noncoding transcript |
|
R5667:Gad1-ps
|
UTSW |
10 |
99,280,395 (GRCm39) |
exon |
noncoding transcript |
|
R5671:Gad1-ps
|
UTSW |
10 |
99,280,395 (GRCm39) |
exon |
noncoding transcript |
|
R5885:Gad1-ps
|
UTSW |
10 |
99,281,009 (GRCm39) |
exon |
noncoding transcript |
|
R5886:Gad1-ps
|
UTSW |
10 |
99,281,009 (GRCm39) |
exon |
noncoding transcript |
|
|
Posted On |
2015-04-16 |