Incidental Mutation 'IGL02259:Prpmp5'
ID286668
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Prpmp5
Ensembl Gene ENSMUSG00000107874
Gene Nameproline-rich protein MP5
SynonymsMP5
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.126) question?
Stock #IGL02259
Quality Score
Status
Chromosome6
Chromosomal Location132311590-132314757 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 132312674 bp
ZygosityHeterozygous
Amino Acid Change Aspartic acid to Glutamic Acid at position 62 (D62E)
Ref Sequence ENSEMBL: ENSMUSP00000047347 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000048686]
Predicted Effect unknown
Transcript: ENSMUST00000048686
AA Change: D62E
SMART Domains Protein: ENSMUSP00000047347
Gene: ENSMUSG00000107874
AA Change: D62E

DomainStartEndE-ValueType
Pfam:Pro-rich 1 136 2.2e-36 PFAM
Pfam:Pro-rich 84 169 6.1e-17 PFAM
Pfam:Pro-rich 131 182 2.5e-10 PFAM
Pfam:Pro-rich 171 228 4.7e-10 PFAM
Pfam:Pro-rich 222 290 1.1e-11 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 34 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
AF529169 A T 9: 89,602,359 H328Q possibly damaging Het
Ang6 A G 14: 44,001,906 F122L probably benign Het
Atm A T 9: 53,518,494 probably benign Het
Ccsap G A 8: 123,845,427 T112M possibly damaging Het
Cd63 T C 10: 128,911,974 S113P probably benign Het
Cntnap5c T C 17: 58,034,862 F183L probably damaging Het
Cux1 T A 5: 136,326,833 S321C probably damaging Het
Cyp2ab1 G A 16: 20,313,147 T281I probably damaging Het
Cyp2c40 A C 19: 39,803,802 C233G probably benign Het
Dnah8 T C 17: 30,759,614 I2955T probably benign Het
Drc7 A G 8: 95,056,105 T33A probably benign Het
Gigyf2 T A 1: 87,411,837 Y481N probably damaging Het
Gsap A T 5: 21,186,400 E13V probably benign Het
Ifna4 A G 4: 88,842,056 K66E probably damaging Het
Kif14 T A 1: 136,500,102 M1103K probably benign Het
Kif6 A T 17: 49,895,891 probably benign Het
Lsm14a G T 7: 34,371,133 P113T probably damaging Het
Med12l T A 3: 59,245,843 N1096K probably damaging Het
Med13 C A 11: 86,357,501 G9W possibly damaging Het
Nbr1 G A 11: 101,577,990 A639T probably damaging Het
Nid2 G T 14: 19,768,209 probably null Het
Numa1 A G 7: 101,987,748 D22G possibly damaging Het
Olfr134 G T 17: 38,175,686 V201L probably benign Het
Olfr62 G A 4: 118,666,437 V307I probably benign Het
Phkg2 A G 7: 127,582,286 probably benign Het
Plcb4 T C 2: 135,910,246 probably null Het
Plch1 C T 3: 63,722,749 probably null Het
Prl8a1 A C 13: 27,582,106 V2G probably benign Het
Spata31 T C 13: 64,921,483 S482P possibly damaging Het
Tbc1d4 A G 14: 101,465,730 C760R probably damaging Het
Tgs1 A G 4: 3,604,743 N722D probably damaging Het
Tmcc2 T C 1: 132,361,160 D28G probably benign Het
Zfp457 C T 13: 67,296,407 A11T possibly damaging Het
Zfp879 T C 11: 50,838,428 S48G probably benign Het
Other mutations in Prpmp5
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01392:Prpmp5 APN 6 132312420 missense unknown
IGL02434:Prpmp5 APN 6 132312376 missense unknown
IGL03238:Prpmp5 APN 6 132312345 missense unknown
R0971:Prpmp5 UTSW 6 132313655 missense unknown
R1900:Prpmp5 UTSW 6 132314698 missense unknown
R3800:Prpmp5 UTSW 6 132312694 missense unknown
R3951:Prpmp5 UTSW 6 132312694 missense unknown
R3952:Prpmp5 UTSW 6 132312694 missense unknown
R3981:Prpmp5 UTSW 6 132312694 missense unknown
R4083:Prpmp5 UTSW 6 132312694 missense unknown
R4348:Prpmp5 UTSW 6 132313661 missense unknown
R4351:Prpmp5 UTSW 6 132313661 missense unknown
R4352:Prpmp5 UTSW 6 132313661 missense unknown
R4353:Prpmp5 UTSW 6 132313661 missense unknown
R6190:Prpmp5 UTSW 6 132312729 missense unknown
R7001:Prpmp5 UTSW 6 132312564 missense unknown
Posted On2015-04-16