Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL02268:Ifna9'

286975

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Ifna9

Ensembl Gene

ENSMUSG00000095270

Gene Name

interferon alpha 9

Synonyms

Ifa9

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.055) question?

Stock #

IGL02268

Quality Score

Status

Chromosome

Chromosomal Location

88591813-88592385 bp(-) (GRCm38)

Type of Mutation

nonsense

DNA Base Change (assembly)

A to T at 88592354 bp

Zygosity

Heterozygous

Amino Acid Change

Leucine to Stop codon at position 11 (L11*)

Ref Sequence

ENSEMBL: ENSMUSP00000099871 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000102807]

Predicted Effect

probably null
Transcript: ENSMUST00000102807
AA Change: L11*

SMART Domains

Protein: ENSMUSP00000099871
Gene: ENSMUSG00000095270
AA Change: L11*

Domain	Start	End	E-Value	Type
signal peptide	1	23	N/A	INTRINSIC
IFabd	58	175	1.68e-67	SMART

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 63 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1500015O10Rik	T	A	1: 43,730,951	C23S	probably damaging	Het
2310057J18Rik	C	T	10: 28,986,246	C16Y	probably benign	Het
5330417C22Rik	C	A	3: 108,467,797	A585S	probably benign	Het
Abca13	C	T	11: 9,290,626	L830F	probably benign	Het
Apcdd1	T	C	18: 62,950,188	V363A	probably damaging	Het
Cachd1	A	G	4: 100,952,097	I260V	possibly damaging	Het
Cass4	T	A	2: 172,427,042	M350K	possibly damaging	Het
Ccdc129	A	T	6: 55,884,688		probably benign	Het
Ccnjl	A	G	11: 43,579,788	T128A	probably benign	Het
Cd6	C	T	19: 10,796,388	G361D	probably benign	Het
Cdh22	T	C	2: 165,123,719		probably benign	Het
Ces2h	T	A	8: 105,019,940	F475Y	probably benign	Het
Col15a1	A	T	4: 47,245,380	T44S	probably damaging	Het
Cplx3	C	T	9: 57,602,458	E86K	possibly damaging	Het
Crbn	A	G	6: 106,795,043	V100A	possibly damaging	Het
D430041D05Rik	C	A	2: 104,241,155	V1267L	possibly damaging	Het
F930017D23Rik	A	G	10: 43,604,409		noncoding transcript	Het
Fam214b	T	A	4: 43,036,468	R88*	probably null	Het
Fastkd3	A	G	13: 68,583,677	D39G	probably damaging	Het
Gm17689	T	C	9: 36,581,870	Y52C	possibly damaging	Het
Golgb1	T	A	16: 36,913,128	S912R	probably benign	Het
H2-T24	T	C	17: 36,017,372	Y73C	probably damaging	Het
Igsf10	A	T	3: 59,331,152	L536*	probably null	Het
Kcnma1	A	T	14: 23,543,076	I215K	probably damaging	Het
Kdm4c	A	C	4: 74,373,716	I857L	possibly damaging	Het
Kptn	A	T	7: 16,123,861	H229L	probably benign	Het
Krt32	A	T	11: 100,088,141	M29K	probably benign	Het
Lama2	A	G	10: 27,001,116		probably benign	Het
Lpcat2b	A	C	5: 107,434,116	D437A	probably damaging	Het
Lrrc8c	T	C	5: 105,607,898	L513P	probably damaging	Het
Mon1a	T	C	9: 107,901,798	V407A	possibly damaging	Het
Myo5c	C	T	9: 75,246,237	P135L	probably damaging	Het
Myof	C	T	19: 37,954,429	V218M	possibly damaging	Het
Myof	T	A	19: 37,974,863	I429F	possibly damaging	Het
Nbas	A	G	12: 13,405,397	D1204G	possibly damaging	Het
Nckap1	G	A	2: 80,528,618	P560S	probably benign	Het
Notch2	G	A	3: 98,137,397	G1545D	probably damaging	Het
Ntrk1	G	A	3: 87,781,531	H572Y	probably damaging	Het
Olfr314	T	C	11: 58,786,725	F164L	probably benign	Het
Olfr873	T	C	9: 20,300,292	S31P	probably damaging	Het
Pcdh15	A	T	10: 74,342,672	D587V	probably damaging	Het
Pik3cb	T	C	9: 99,046,556	Y882C	probably benign	Het
Plch1	T	A	3: 63,699,283	*1074C	probably null	Het
Plcxd1	T	C	5: 110,100,274		probably benign	Het
Ppp2r2d	A	G	7: 138,872,971	N27S	probably null	Het
Prkar2a	A	G	9: 108,746,953	M390V	probably benign	Het
Rab3gap1	A	G	1: 127,868,958	T18A	probably damaging	Het
Ranbp2	T	C	10: 58,493,653		probably benign	Het
Rasl12	T	C	9: 65,398,664	S34P	probably damaging	Het
Rpusd3	A	T	6: 113,418,857	L65Q	possibly damaging	Het
Rtf2	A	G	2: 172,468,719	K290R	probably damaging	Het
Rwdd4a	T	A	8: 47,550,696	L179*	probably null	Het
Scgb1b24	A	G	7: 33,744,963	E87G	possibly damaging	Het
Sgo2a	A	G	1: 58,017,722	I1022V	probably benign	Het
Smg1	A	C	7: 118,182,541	I1174M	probably benign	Het
Spata17	A	T	1: 187,140,398	M72K	probably damaging	Het
Synpo2	G	A	3: 123,116,983	P338S	probably damaging	Het
Tpi1	G	A	6: 124,814,124	T50I	probably benign	Het
Trpm1	A	G	7: 64,217,614	E354G	probably damaging	Het
Uba2	A	G	7: 34,142,736		probably null	Het
Wnk1	G	A	6: 119,937,373	R1823*	probably null	Het
Zfp248	A	C	6: 118,453,840		probably benign	Het
Zfp51	A	T	17: 21,463,419	K99*	probably null	Het

Other mutations in Ifna9

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01788:Ifna9	APN	4	88591860	missense	probably damaging	1.00
R0579:Ifna9	UTSW	4	88592271	missense	possibly damaging	0.84
R1530:Ifna9	UTSW	4	88592172	missense	possibly damaging	0.83
R1663:Ifna9	UTSW	4	88591983	missense	probably benign	0.00
R1872:Ifna9	UTSW	4	88592255	missense	probably damaging	0.97
R3923:Ifna9	UTSW	4	88592271	missense	possibly damaging	0.84
R4534:Ifna9	UTSW	4	88592048	missense	possibly damaging	0.76
R4882:Ifna9	UTSW	4	88592303	missense	probably benign	0.01
R5440:Ifna9	UTSW	4	88591811	splice site	probably null
R6008:Ifna9	UTSW	4	88592363	missense	probably null	1.00
R6464:Ifna9	UTSW	4	88592250	missense	possibly damaging	0.93
R6584:Ifna9	UTSW	4	88592138	missense	probably damaging	0.99
R6899:Ifna9	UTSW	4	88592063	missense	probably damaging	1.00

Posted On

2015-04-16