Incidental Mutation 'IGL00910:Fam84a'
ID28709
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Fam84a
Ensembl Gene ENSMUSG00000020607
Gene Namefamily with sequence similarity 84, member A
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.118) question?
Stock #IGL00910
Quality Score
Status
Chromosome12
Chromosomal Location14146830-14152054 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to C at 14150526 bp
ZygosityHeterozygous
Amino Acid Change Serine to Glycine at position 67 (S67G)
Ref Sequence ENSEMBL: ENSMUSP00000020926 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000020926] [ENSMUST00000221405]
Predicted Effect probably benign
Transcript: ENSMUST00000020926
AA Change: S67G

PolyPhen 2 Score 0.141 (Sensitivity: 0.92; Specificity: 0.86)
SMART Domains Protein: ENSMUSP00000020926
Gene: ENSMUSG00000020607
AA Change: S67G

DomainStartEndE-ValueType
low complexity region 57 69 N/A INTRINSIC
low complexity region 71 81 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000221405
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 20 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
5031439G07Rik A G 15: 84,955,819 L109P probably damaging Het
Aacs T A 5: 125,508,708 M316K probably benign Het
Adarb2 T C 13: 8,672,433 V375A probably damaging Het
Adgra2 C A 8: 27,085,983 A13E possibly damaging Het
Ankrd34c A T 9: 89,729,026 S421T probably benign Het
Bpifa6 A T 2: 153,990,466 M298L probably benign Het
Casq2 T C 3: 102,110,231 probably benign Het
Ckap5 A G 2: 91,576,050 T762A probably benign Het
Dhx38 A G 8: 109,559,034 V389A probably benign Het
Dnah7b A T 1: 46,066,729 probably benign Het
Dnajc7 A T 11: 100,599,191 F79L possibly damaging Het
Dyrk3 A G 1: 131,136,336 I3T possibly damaging Het
Fchsd2 T C 7: 101,277,626 I641T probably benign Het
Furin A G 7: 80,390,996 V698A probably benign Het
Prl2c5 G A 13: 13,189,476 probably null Het
Ryr3 A T 2: 112,728,934 probably benign Het
Serpina6 G T 12: 103,651,965 probably benign Het
Slc6a2 A G 8: 92,996,100 Y575C probably damaging Het
Trim9 T C 12: 70,347,113 E19G probably damaging Het
Tsfm G T 10: 127,028,359 probably benign Het
Other mutations in Fam84a
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01446:Fam84a APN 12 14149928 missense probably damaging 1.00
IGL02684:Fam84a APN 12 14150645 missense probably damaging 0.97
Grade UTSW 12 14149863 missense probably damaging 0.99
R1514:Fam84a UTSW 12 14149863 missense probably damaging 0.99
R1583:Fam84a UTSW 12 14150408 missense probably benign 0.25
R1800:Fam84a UTSW 12 14150225 missense probably damaging 0.98
R6074:Fam84a UTSW 12 14150511 missense probably benign 0.06
R6259:Fam84a UTSW 12 14150645 missense probably damaging 0.99
R7169:Fam84a UTSW 12 14150618 missense probably damaging 0.99
Posted On2013-04-17