Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL00952:Dnah11'

28763

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Dnah11

Ensembl Gene

ENSMUSG00000018581

Gene Name

dynein, axonemal, heavy chain 11

Synonyms

b2b598Clo, Dnahc11, b2b1289Clo, lrd, b2b1727Clo, b2b1203Clo, b2b1279Clo

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.492) question?

Stock #

IGL00952

Quality Score

Status

Chromosome

Chromosomal Location

117877982-118199043 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 118196651 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Alanine at position 115 (T115A)

Ref Sequence

ENSEMBL: ENSMUSP00000081867 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000084806]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000084806
AA Change: T115A

PolyPhen 2 Score 0.558 (Sensitivity: 0.88; Specificity: 0.91)

SMART Domains

Protein: ENSMUSP00000081867
Gene: ENSMUSG00000018581
AA Change: T115A

Domain	Start	End	E-Value	Type
low complexity region	18	28	N/A	INTRINSIC
Pfam:DHC_N1	218	794	1.6e-162	PFAM
low complexity region	1266	1282	N/A	INTRINSIC
Pfam:DHC_N2	1297	1705	1e-130	PFAM
low complexity region	1757	1773	N/A	INTRINSIC
AAA	1869	1963	1.51e0	SMART
Pfam:AAA_5	2150	2286	1.6e-12	PFAM
AAA	2474	2619	1.48e-1	SMART
AAA	2819	2931	4.57e-1	SMART
Pfam:MT	3069	3413	3.2e-162	PFAM
Pfam:AAA_9	3434	3656	2.9e-88	PFAM
Pfam:Dynein_heavy	3790	4486	7.1e-235	PFAM

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a ciliary outer dynein arm protein and is a member of the dynein heavy chain family. It is a microtubule-dependent motor ATPase and has been reported to be involved in the movement of respiratory cilia. Mutations in this gene have been implicated in causing Kartagener Syndrome (a combination of situs inversus totalis and Primary Ciliary Dyskinesia (PCD), also called Immotile Cilia Syndrome 1 (ICS1)) and male sterility. [provided by RefSeq, Mar 2013]
PHENOTYPE: Approximately half of live-born homozygous mutants show situs inversus indicating that this gene is no longer properly controlling left-right asymmetry. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 50 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1810009J06Rik	T	G	6: 40,964,799 (GRCm38)	I4S	probably benign	Het
Abca8b	A	G	11: 109,969,060 (GRCm38)		probably null	Het
Aftph	A	T	11: 20,727,483 (GRCm38)	V42E	probably damaging	Het
AI467606	A	G	7: 127,092,702 (GRCm38)	S150G	probably damaging	Het
Art4	T	C	6: 136,854,820 (GRCm38)	N108D	possibly damaging	Het
B9d1	G	A	11: 61,512,678 (GRCm38)	V167I	possibly damaging	Het
Ccdc47	A	T	11: 106,203,532 (GRCm38)		probably null	Het
Ccdc96	T	A	5: 36,485,080 (GRCm38)		probably benign	Het
Cfap44	A	G	16: 44,421,275 (GRCm38)	I670V	probably benign	Het
Col18a1	T	G	10: 77,069,979 (GRCm38)	K909Q	possibly damaging	Het
Col8a2	A	G	4: 126,309,791 (GRCm38)	Y59C	probably damaging	Het
Coro6	A	T	11: 77,468,465 (GRCm38)	D288V	probably damaging	Het
Cul4a	C	T	8: 13,146,562 (GRCm38)	L739F	probably damaging	Het
Dmxl2	C	T	9: 54,416,882 (GRCm38)	V1073I	probably damaging	Het
Fdx1l	A	G	9: 21,073,262 (GRCm38)		probably null	Het
Flnc	C	T	6: 29,459,547 (GRCm38)	Q2549*	probably null	Het
Foxn2	T	C	17: 88,475,880 (GRCm38)	C188R	probably benign	Het
Hnrnpm	C	A	17: 33,649,902 (GRCm38)	R517L	probably damaging	Het
Ilf3	T	C	9: 21,396,051 (GRCm38)	L343P	probably damaging	Het
Itgb2l	C	T	16: 96,426,750 (GRCm38)	G518S	probably damaging	Het
Itpr2	T	A	6: 146,158,961 (GRCm38)	I2486F	probably damaging	Het
Kat2a	A	G	11: 100,706,151 (GRCm38)	V681A	probably damaging	Het
Kif17	A	G	4: 138,262,708 (GRCm38)	N69S	possibly damaging	Het
Kif26b	G	A	1: 178,932,205 (GRCm38)	D2106N	probably damaging	Het
Klf6	A	G	13: 5,861,681 (GRCm38)	T15A	probably benign	Het
Lyst	A	G	13: 13,678,107 (GRCm38)	T2231A	probably benign	Het
Mark4	T	C	7: 19,431,824 (GRCm38)	T515A	possibly damaging	Het
Mast3	A	T	8: 70,780,683 (GRCm38)		probably benign	Het
Nalcn	T	C	14: 123,348,789 (GRCm38)	K722R	probably benign	Het
Ncf2	G	A	1: 152,836,106 (GRCm38)	E524K	probably benign	Het
Olfr1135	A	T	2: 87,671,815 (GRCm38)	I184N	probably damaging	Het
Olfr510	A	G	7: 108,668,238 (GRCm38)	N274S	possibly damaging	Het
Olfr681	A	G	7: 105,122,407 (GRCm38)		probably null	Het
Olfr895	A	T	9: 38,268,505 (GRCm38)		probably benign	Het
Plcg2	A	T	8: 117,607,217 (GRCm38)	M910L	probably benign	Het
Pramef17	T	C	4: 143,993,324 (GRCm38)	H157R	probably benign	Het
Rai1	A	T	11: 60,187,992 (GRCm38)	K961*	probably null	Het
Rsph14	T	C	10: 75,029,769 (GRCm38)	D112G	probably benign	Het
Sgo1	T	A	17: 53,687,247 (GRCm38)	D59V	probably damaging	Het
Slc22a29	A	T	19: 8,217,857 (GRCm38)	V138E	probably damaging	Het
Slc9a1	T	A	4: 133,416,382 (GRCm38)	V393D	probably damaging	Het
Smg6	A	G	11: 74,929,148 (GRCm38)	R82G	probably benign	Het
Sppl3	T	C	5: 115,074,876 (GRCm38)	S55P	probably benign	Het
Srsf12	A	C	4: 33,226,103 (GRCm38)	Q122P	possibly damaging	Het
Tas1r2	T	C	4: 139,655,252 (GRCm38)	M67T	probably benign	Het
Thnsl1	G	A	2: 21,211,956 (GRCm38)	V174I	possibly damaging	Het
Thumpd1	A	G	7: 119,717,009 (GRCm38)	V239A	possibly damaging	Het
Tnxb	T	G	17: 34,713,128 (GRCm38)	Y2212D	probably damaging	Het
Trim40	T	C	17: 36,882,397 (GRCm38)	*213W	probably null	Het
Ttc16	T	C	2: 32,770,247 (GRCm38)	D183G	probably damaging	Het

Other mutations in Dnah11

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00341:Dnah11	APN	12	118,198,745 (GRCm38)	missense	probably benign	0.28
IGL00422:Dnah11	APN	12	118,068,096 (GRCm38)	missense	probably damaging	1.00
IGL00436:Dnah11	APN	12	118,036,459 (GRCm38)	missense	possibly damaging	0.56
IGL00540:Dnah11	APN	12	118,186,922 (GRCm38)	missense	probably benign	0.01
IGL00687:Dnah11	APN	12	117,922,004 (GRCm38)	splice site	probably benign
IGL00833:Dnah11	APN	12	118,179,580 (GRCm38)	missense	probably damaging	1.00
IGL00906:Dnah11	APN	12	117,911,202 (GRCm38)	missense	probably damaging	1.00
IGL01111:Dnah11	APN	12	118,142,934 (GRCm38)	splice site	probably benign
IGL01121:Dnah11	APN	12	118,050,695 (GRCm38)	missense	probably benign	0.02
IGL01143:Dnah11	APN	12	118,012,740 (GRCm38)	missense	probably damaging	1.00
IGL01359:Dnah11	APN	12	117,982,999 (GRCm38)	missense	probably damaging	0.99
IGL01372:Dnah11	APN	12	118,192,399 (GRCm38)	missense	probably damaging	1.00
IGL01410:Dnah11	APN	12	118,047,256 (GRCm38)	nonsense	probably null
IGL01418:Dnah11	APN	12	117,987,482 (GRCm38)	nonsense	probably null
IGL01444:Dnah11	APN	12	118,020,232 (GRCm38)	missense	possibly damaging	0.91
IGL01606:Dnah11	APN	12	117,983,032 (GRCm38)	missense	probably benign	0.15
IGL01645:Dnah11	APN	12	118,186,998 (GRCm38)	missense	possibly damaging	0.90
IGL01932:Dnah11	APN	12	118,192,270 (GRCm38)	splice site	probably benign
IGL02104:Dnah11	APN	12	118,192,390 (GRCm38)	missense	probably benign
IGL02151:Dnah11	APN	12	118,059,888 (GRCm38)	splice site	probably benign
IGL02189:Dnah11	APN	12	118,082,579 (GRCm38)	missense	probably benign	0.00
IGL02417:Dnah11	APN	12	118,057,180 (GRCm38)	missense	probably damaging	1.00
IGL02421:Dnah11	APN	12	118,186,902 (GRCm38)	missense	probably damaging	1.00
IGL02444:Dnah11	APN	12	117,975,873 (GRCm38)	splice site	probably benign
IGL02474:Dnah11	APN	12	118,027,445 (GRCm38)	splice site	probably null
IGL02526:Dnah11	APN	12	118,179,618 (GRCm38)	missense	possibly damaging	0.70
IGL02887:Dnah11	APN	12	117,911,040 (GRCm38)	missense	probably damaging	1.00
IGL03011:Dnah11	APN	12	118,012,377 (GRCm38)	missense	probably benign	0.08
IGL03061:Dnah11	APN	12	117,903,121 (GRCm38)	missense	probably damaging	1.00
IGL03182:Dnah11	APN	12	118,030,291 (GRCm38)	missense	probably damaging	0.99
IGL03220:Dnah11	APN	12	118,105,985 (GRCm38)	missense	probably benign
IGL03238:Dnah11	APN	12	118,109,898 (GRCm38)	missense	probably damaging	1.00
IGL03493:Dnah11	APN	12	118,012,798 (GRCm38)	missense	probably benign	0.00
P0045:Dnah11	UTSW	12	118,030,327 (GRCm38)	missense	probably benign
R0009:Dnah11	UTSW	12	118,045,522 (GRCm38)	missense	possibly damaging	0.90
R0066:Dnah11	UTSW	12	118,126,886 (GRCm38)	missense	probably benign	0.05
R0172:Dnah11	UTSW	12	117,987,453 (GRCm38)	missense	probably damaging	1.00
R0206:Dnah11	UTSW	12	118,043,774 (GRCm38)	missense	probably damaging	0.98
R0206:Dnah11	UTSW	12	118,043,774 (GRCm38)	missense	probably damaging	0.98
R0208:Dnah11	UTSW	12	118,043,774 (GRCm38)	missense	probably damaging	0.98
R0230:Dnah11	UTSW	12	117,983,056 (GRCm38)	nonsense	probably null
R0270:Dnah11	UTSW	12	118,041,013 (GRCm38)	missense	probably damaging	1.00
R0311:Dnah11	UTSW	12	118,127,133 (GRCm38)	missense	probably benign	0.03
R0325:Dnah11	UTSW	12	118,012,339 (GRCm38)	missense	probably benign
R0370:Dnah11	UTSW	12	117,995,227 (GRCm38)	missense	probably benign
R0416:Dnah11	UTSW	12	117,911,058 (GRCm38)	missense	probably damaging	1.00
R0505:Dnah11	UTSW	12	118,106,510 (GRCm38)	missense	probably damaging	1.00
R0540:Dnah11	UTSW	12	118,082,511 (GRCm38)	missense	probably damaging	1.00
R0554:Dnah11	UTSW	12	117,931,178 (GRCm38)	missense	probably benign	0.01
R0607:Dnah11	UTSW	12	118,082,511 (GRCm38)	missense	probably damaging	1.00
R0620:Dnah11	UTSW	12	117,987,469 (GRCm38)	missense	probably damaging	1.00
R0635:Dnah11	UTSW	12	118,007,996 (GRCm38)	missense	probably damaging	1.00
R0755:Dnah11	UTSW	12	118,198,625 (GRCm38)	missense	probably benign	0.17
R0755:Dnah11	UTSW	12	117,954,829 (GRCm38)	missense	possibly damaging	0.95
R0789:Dnah11	UTSW	12	117,911,232 (GRCm38)	missense	probably damaging	1.00
R0833:Dnah11	UTSW	12	118,196,662 (GRCm38)	missense	probably benign	0.01
R0835:Dnah11	UTSW	12	117,916,788 (GRCm38)	missense	probably damaging	1.00
R0836:Dnah11	UTSW	12	118,196,662 (GRCm38)	missense	probably benign	0.01
R0846:Dnah11	UTSW	12	117,933,850 (GRCm38)	missense	probably damaging	0.97
R0865:Dnah11	UTSW	12	118,190,844 (GRCm38)	nonsense	probably null
R0928:Dnah11	UTSW	12	118,045,562 (GRCm38)	missense	probably damaging	1.00
R0939:Dnah11	UTSW	12	118,060,407 (GRCm38)	missense	probably damaging	1.00
R1203:Dnah11	UTSW	12	117,933,812 (GRCm38)	missense	possibly damaging	0.81
R1394:Dnah11	UTSW	12	117,972,364 (GRCm38)	missense	possibly damaging	0.75
R1398:Dnah11	UTSW	12	118,057,106 (GRCm38)	nonsense	probably null
R1465:Dnah11	UTSW	12	118,038,695 (GRCm38)	missense	probably damaging	1.00
R1465:Dnah11	UTSW	12	118,038,695 (GRCm38)	missense	probably damaging	1.00
R1500:Dnah11	UTSW	12	118,012,829 (GRCm38)	splice site	probably null
R1535:Dnah11	UTSW	12	118,018,730 (GRCm38)	missense	probably damaging	1.00
R1539:Dnah11	UTSW	12	117,931,256 (GRCm38)	missense	probably benign	0.01
R1554:Dnah11	UTSW	12	118,082,499 (GRCm38)	missense	possibly damaging	0.92
R1574:Dnah11	UTSW	12	118,060,317 (GRCm38)	missense	probably damaging	1.00
R1574:Dnah11	UTSW	12	118,060,317 (GRCm38)	missense	probably damaging	1.00
R1615:Dnah11	UTSW	12	118,050,722 (GRCm38)	missense	probably damaging	1.00
R1618:Dnah11	UTSW	12	118,015,465 (GRCm38)	missense	probably damaging	0.98
R1638:Dnah11	UTSW	12	118,015,419 (GRCm38)	missense	possibly damaging	0.81
R1659:Dnah11	UTSW	12	118,120,724 (GRCm38)	missense	possibly damaging	0.94
R1671:Dnah11	UTSW	12	117,916,788 (GRCm38)	missense	probably damaging	1.00
R1678:Dnah11	UTSW	12	117,933,845 (GRCm38)	missense	possibly damaging	0.50
R1699:Dnah11	UTSW	12	118,190,868 (GRCm38)	missense	probably damaging	1.00
R1712:Dnah11	UTSW	12	118,196,644 (GRCm38)	missense	probably benign	0.32
R1728:Dnah11	UTSW	12	117,916,931 (GRCm38)	missense	probably damaging	1.00
R1729:Dnah11	UTSW	12	117,916,931 (GRCm38)	missense	probably damaging	1.00
R1764:Dnah11	UTSW	12	118,190,825 (GRCm38)	missense	probably benign	0.31
R1780:Dnah11	UTSW	12	118,027,558 (GRCm38)	missense	probably damaging	1.00
R1789:Dnah11	UTSW	12	118,038,780 (GRCm38)	missense	probably damaging	0.99
R1800:Dnah11	UTSW	12	117,916,788 (GRCm38)	missense	probably damaging	1.00
R1863:Dnah11	UTSW	12	118,063,852 (GRCm38)	missense	possibly damaging	0.92
R1892:Dnah11	UTSW	12	118,106,474 (GRCm38)	missense	possibly damaging	0.53
R1907:Dnah11	UTSW	12	118,127,556 (GRCm38)	missense	possibly damaging	0.66
R1964:Dnah11	UTSW	12	118,142,292 (GRCm38)	missense	possibly damaging	0.56
R1967:Dnah11	UTSW	12	117,916,788 (GRCm38)	missense	probably damaging	1.00
R1997:Dnah11	UTSW	12	118,082,468 (GRCm38)	missense	possibly damaging	0.64
R2086:Dnah11	UTSW	12	118,113,871 (GRCm38)	missense	possibly damaging	0.82
R2092:Dnah11	UTSW	12	118,012,716 (GRCm38)	missense	possibly damaging	0.50
R2108:Dnah11	UTSW	12	118,020,353 (GRCm38)	missense	probably damaging	1.00
R2140:Dnah11	UTSW	12	118,008,810 (GRCm38)	missense	probably benign	0.01
R2261:Dnah11	UTSW	12	117,966,639 (GRCm38)	missense	probably damaging	0.99
R2261:Dnah11	UTSW	12	117,880,025 (GRCm38)	missense	probably benign	0.06
R2262:Dnah11	UTSW	12	117,966,639 (GRCm38)	missense	probably damaging	0.99
R2262:Dnah11	UTSW	12	117,880,025 (GRCm38)	missense	probably benign	0.06
R2263:Dnah11	UTSW	12	117,966,639 (GRCm38)	missense	probably damaging	0.99
R2263:Dnah11	UTSW	12	117,880,025 (GRCm38)	missense	probably benign	0.06
R2328:Dnah11	UTSW	12	117,886,686 (GRCm38)	missense	probably damaging	0.98
R2352:Dnah11	UTSW	12	117,928,330 (GRCm38)	missense	probably damaging	1.00
R2410:Dnah11	UTSW	12	118,027,527 (GRCm38)	missense	probably damaging	1.00
R2885:Dnah11	UTSW	12	117,987,427 (GRCm38)	nonsense	probably null
R3499:Dnah11	UTSW	12	117,911,023 (GRCm38)	missense	probably damaging	1.00
R3741:Dnah11	UTSW	12	118,131,341 (GRCm38)	missense	probably benign	0.05
R3742:Dnah11	UTSW	12	118,131,341 (GRCm38)	missense	probably benign	0.05
R3779:Dnah11	UTSW	12	118,130,713 (GRCm38)	splice site	probably benign
R3785:Dnah11	UTSW	12	118,017,602 (GRCm38)	missense	probably damaging	1.00
R3883:Dnah11	UTSW	12	117,978,453 (GRCm38)	splice site	probably benign
R4014:Dnah11	UTSW	12	117,974,914 (GRCm38)	missense	probably benign	0.16
R4043:Dnah11	UTSW	12	117,879,943 (GRCm38)	missense	probably damaging	1.00
R4072:Dnah11	UTSW	12	118,106,492 (GRCm38)	missense	probably damaging	1.00
R4073:Dnah11	UTSW	12	118,045,678 (GRCm38)	missense	probably benign	0.01
R4074:Dnah11	UTSW	12	118,045,678 (GRCm38)	missense	probably benign	0.01
R4076:Dnah11	UTSW	12	118,045,678 (GRCm38)	missense	probably benign	0.01
R4201:Dnah11	UTSW	12	117,966,659 (GRCm38)	missense	possibly damaging	0.63
R4224:Dnah11	UTSW	12	118,130,892 (GRCm38)	missense	probably benign	0.06
R4233:Dnah11	UTSW	12	117,916,791 (GRCm38)	missense	probably damaging	1.00
R4358:Dnah11	UTSW	12	118,125,843 (GRCm38)	nonsense	probably null
R4430:Dnah11	UTSW	12	117,983,011 (GRCm38)	missense	probably benign	0.26
R4465:Dnah11	UTSW	12	117,987,451 (GRCm38)	missense	probably benign	0.09
R4489:Dnah11	UTSW	12	117,916,896 (GRCm38)	missense	probably benign	0.31
R4572:Dnah11	UTSW	12	118,010,125 (GRCm38)	missense	probably benign	0.00
R4574:Dnah11	UTSW	12	118,012,255 (GRCm38)	critical splice donor site	probably null
R4657:Dnah11	UTSW	12	118,192,427 (GRCm38)	missense	probably benign	0.02
R4709:Dnah11	UTSW	12	118,018,760 (GRCm38)	missense	probably benign	0.26
R4740:Dnah11	UTSW	12	118,120,544 (GRCm38)	missense	probably benign	0.28
R4803:Dnah11	UTSW	12	118,127,608 (GRCm38)	missense	possibly damaging	0.50
R4896:Dnah11	UTSW	12	117,995,200 (GRCm38)	missense	probably damaging	1.00
R4908:Dnah11	UTSW	12	118,126,883 (GRCm38)	missense	probably benign	0.37
R5018:Dnah11	UTSW	12	118,130,728 (GRCm38)	missense	probably benign	0.00
R5071:Dnah11	UTSW	12	118,082,453 (GRCm38)	nonsense	probably null
R5074:Dnah11	UTSW	12	118,082,453 (GRCm38)	nonsense	probably null
R5080:Dnah11	UTSW	12	118,198,830 (GRCm38)	start codon destroyed	probably null	0.01
R5097:Dnah11	UTSW	12	118,017,700 (GRCm38)	missense	probably damaging	1.00
R5131:Dnah11	UTSW	12	117,954,751 (GRCm38)	missense	probably damaging	1.00
R5215:Dnah11	UTSW	12	118,157,361 (GRCm38)	missense	probably benign	0.09
R5252:Dnah11	UTSW	12	118,125,941 (GRCm38)	missense	probably damaging	1.00
R5296:Dnah11	UTSW	12	117,883,416 (GRCm38)	missense	probably damaging	1.00
R5308:Dnah11	UTSW	12	118,085,680 (GRCm38)	missense	possibly damaging	0.60
R5368:Dnah11	UTSW	12	117,954,893 (GRCm38)	missense	probably damaging	1.00
R5383:Dnah11	UTSW	12	118,085,697 (GRCm38)	missense	probably damaging	0.99
R5499:Dnah11	UTSW	12	118,106,474 (GRCm38)	missense	possibly damaging	0.53
R5503:Dnah11	UTSW	12	117,880,451 (GRCm38)	critical splice donor site	probably null
R5546:Dnah11	UTSW	12	117,975,848 (GRCm38)	missense	possibly damaging	0.83
R5578:Dnah11	UTSW	12	118,018,802 (GRCm38)	missense	probably damaging	0.99
R5657:Dnah11	UTSW	12	117,883,617 (GRCm38)	missense	probably damaging	1.00
R5702:Dnah11	UTSW	12	118,113,907 (GRCm38)	missense	probably benign	0.04
R5706:Dnah11	UTSW	12	118,023,935 (GRCm38)	missense	probably damaging	1.00
R5727:Dnah11	UTSW	12	118,127,106 (GRCm38)	missense	probably damaging	1.00
R5737:Dnah11	UTSW	12	118,192,390 (GRCm38)	missense	probably benign
R5884:Dnah11	UTSW	12	118,177,534 (GRCm38)	missense	probably benign	0.00
R5900:Dnah11	UTSW	12	118,082,431 (GRCm38)	splice site	probably null
R5905:Dnah11	UTSW	12	117,954,924 (GRCm38)	missense	probably damaging	1.00
R5928:Dnah11	UTSW	12	117,914,636 (GRCm38)	splice site	probably null
R5973:Dnah11	UTSW	12	118,110,952 (GRCm38)	missense	probably benign	0.02
R6024:Dnah11	UTSW	12	118,030,272 (GRCm38)	missense	probably benign	0.34
R6056:Dnah11	UTSW	12	117,928,456 (GRCm38)	missense	probably benign	0.03
R6075:Dnah11	UTSW	12	118,104,851 (GRCm38)	missense	probably damaging	1.00
R6092:Dnah11	UTSW	12	117,928,456 (GRCm38)	missense	probably benign
R6191:Dnah11	UTSW	12	118,190,897 (GRCm38)	missense	probably benign
R6197:Dnah11	UTSW	12	118,179,747 (GRCm38)	missense	probably benign	0.03
R6262:Dnah11	UTSW	12	117,931,178 (GRCm38)	missense	probably damaging	0.98
R6321:Dnah11	UTSW	12	118,142,292 (GRCm38)	missense	possibly damaging	0.56
R6454:Dnah11	UTSW	12	117,916,855 (GRCm38)	missense	probably benign	0.01
R6614:Dnah11	UTSW	12	117,886,676 (GRCm38)	missense	possibly damaging	0.72
R6694:Dnah11	UTSW	12	118,186,882 (GRCm38)	splice site	probably null
R6712:Dnah11	UTSW	12	118,050,722 (GRCm38)	missense	probably damaging	1.00
R6720:Dnah11	UTSW	12	118,045,646 (GRCm38)	missense	probably damaging	1.00
R6742:Dnah11	UTSW	12	118,113,894 (GRCm38)	missense	possibly damaging	0.82
R6806:Dnah11	UTSW	12	117,987,676 (GRCm38)	splice site	probably null
R6895:Dnah11	UTSW	12	117,995,191 (GRCm38)	missense	probably damaging	0.99
R6939:Dnah11	UTSW	12	118,106,562 (GRCm38)	missense	probably damaging	1.00
R6940:Dnah11	UTSW	12	118,198,768 (GRCm38)	missense	probably benign
R6945:Dnah11	UTSW	12	118,060,310 (GRCm38)	missense	probably damaging	1.00
R6958:Dnah11	UTSW	12	117,933,809 (GRCm38)	missense	probably damaging	1.00
R6970:Dnah11	UTSW	12	118,108,944 (GRCm38)	missense	probably benign	0.00
R6976:Dnah11	UTSW	12	118,198,643 (GRCm38)	missense	probably benign	0.16
R7000:Dnah11	UTSW	12	118,017,661 (GRCm38)	missense	probably damaging	1.00
R7011:Dnah11	UTSW	12	117,922,018 (GRCm38)	frame shift	probably null
R7101:Dnah11	UTSW	12	118,068,145 (GRCm38)	missense	probably benign
R7106:Dnah11	UTSW	12	117,961,149 (GRCm38)	missense	probably benign	0.15
R7203:Dnah11	UTSW	12	118,045,522 (GRCm38)	missense	possibly damaging	0.90
R7219:Dnah11	UTSW	12	118,126,889 (GRCm38)	missense	probably benign	0.00
R7219:Dnah11	UTSW	12	118,041,095 (GRCm38)	missense	possibly damaging	0.95
R7308:Dnah11	UTSW	12	117,995,275 (GRCm38)	missense	probably damaging	1.00
R7361:Dnah11	UTSW	12	118,018,742 (GRCm38)	missense	probably damaging	1.00
R7367:Dnah11	UTSW	12	117,987,442 (GRCm38)	missense	possibly damaging	0.59
R7399:Dnah11	UTSW	12	118,125,785 (GRCm38)	missense	probably damaging	1.00
R7399:Dnah11	UTSW	12	118,027,477 (GRCm38)	missense	probably benign	0.00
R7404:Dnah11	UTSW	12	118,104,808 (GRCm38)	missense	probably benign	0.36
R7473:Dnah11	UTSW	12	117,903,176 (GRCm38)	missense	probably benign	0.19
R7545:Dnah11	UTSW	12	117,931,204 (GRCm38)	missense	probably damaging	1.00
R7608:Dnah11	UTSW	12	118,140,770 (GRCm38)	splice site	probably null
R7625:Dnah11	UTSW	12	118,196,642 (GRCm38)	missense	probably benign
R7761:Dnah11	UTSW	12	118,023,913 (GRCm38)	missense	probably damaging	1.00
R7879:Dnah11	UTSW	12	118,041,009 (GRCm38)	missense	probably damaging	1.00
R7881:Dnah11	UTSW	12	117,987,502 (GRCm38)	missense	probably benign	0.04
R7904:Dnah11	UTSW	12	117,903,268 (GRCm38)	missense	possibly damaging	0.72
R8100:Dnah11	UTSW	12	117,966,633 (GRCm38)	missense	probably damaging	0.99
R8179:Dnah11	UTSW	12	117,878,549 (GRCm38)	missense	possibly damaging	0.90
R8192:Dnah11	UTSW	12	118,012,446 (GRCm38)	missense	probably benign
R8254:Dnah11	UTSW	12	117,878,524 (GRCm38)	missense	possibly damaging	0.89
R8268:Dnah11	UTSW	12	118,027,508 (GRCm38)	nonsense	probably null
R8272:Dnah11	UTSW	12	118,111,017 (GRCm38)	missense	probably benign	0.01
R8344:Dnah11	UTSW	12	118,085,731 (GRCm38)	missense	probably benign	0.00
R8515:Dnah11	UTSW	12	117,975,798 (GRCm38)	missense	probably damaging	1.00
R8528:Dnah11	UTSW	12	118,008,803 (GRCm38)	missense	probably damaging	0.96
R8557:Dnah11	UTSW	12	117,878,512 (GRCm38)	missense	probably benign
R8676:Dnah11	UTSW	12	118,190,804 (GRCm38)	missense	probably damaging	1.00
R8738:Dnah11	UTSW	12	118,085,649 (GRCm38)	critical splice donor site	probably null
R8773:Dnah11	UTSW	12	117,995,215 (GRCm38)	missense	possibly damaging	0.94
R8818:Dnah11	UTSW	12	117,911,029 (GRCm38)	missense	probably damaging	1.00
R8855:Dnah11	UTSW	12	118,192,372 (GRCm38)	missense	probably benign	0.03
R8866:Dnah11	UTSW	12	118,192,372 (GRCm38)	missense	probably benign	0.03
R8881:Dnah11	UTSW	12	118,126,815 (GRCm38)	missense	probably benign	0.05
R8881:Dnah11	UTSW	12	118,113,912 (GRCm38)	missense	probably benign	0.00
R8920:Dnah11	UTSW	12	118,113,939 (GRCm38)	missense	probably damaging	0.99
R8944:Dnah11	UTSW	12	118,127,646 (GRCm38)	missense	possibly damaging	0.63
R8945:Dnah11	UTSW	12	118,023,983 (GRCm38)	missense	probably benign	0.36
R8962:Dnah11	UTSW	12	117,954,895 (GRCm38)	missense	probably damaging	1.00
R8962:Dnah11	UTSW	12	117,952,538 (GRCm38)	missense	probably damaging	1.00
R9059:Dnah11	UTSW	12	118,130,843 (GRCm38)	missense	probably benign	0.00
R9155:Dnah11	UTSW	12	118,027,516 (GRCm38)	missense	probably damaging	0.99
R9162:Dnah11	UTSW	12	118,027,516 (GRCm38)	missense	probably damaging	0.99
R9164:Dnah11	UTSW	12	118,027,516 (GRCm38)	missense	probably damaging	0.99
R9171:Dnah11	UTSW	12	117,931,183 (GRCm38)	missense	probably damaging	0.99
R9186:Dnah11	UTSW	12	118,190,897 (GRCm38)	missense	probably benign
R9205:Dnah11	UTSW	12	118,027,516 (GRCm38)	missense	probably damaging	0.99
R9208:Dnah11	UTSW	12	118,027,516 (GRCm38)	missense	probably damaging	0.99
R9234:Dnah11	UTSW	12	117,987,360 (GRCm38)	missense	probably damaging	1.00
R9264:Dnah11	UTSW	12	118,027,527 (GRCm38)	missense	probably damaging	1.00
R9290:Dnah11	UTSW	12	118,027,516 (GRCm38)	missense	probably damaging	0.99
R9291:Dnah11	UTSW	12	118,027,516 (GRCm38)	missense	probably damaging	0.99
R9315:Dnah11	UTSW	12	118,179,606 (GRCm38)	missense	probably benign	0.11
R9353:Dnah11	UTSW	12	118,179,699 (GRCm38)	missense	probably benign	0.00
R9375:Dnah11	UTSW	12	117,920,968 (GRCm38)	missense	possibly damaging	0.67
R9392:Dnah11	UTSW	12	118,177,555 (GRCm38)	missense	probably benign	0.00
R9392:Dnah11	UTSW	12	118,047,320 (GRCm38)	nonsense	probably null
R9433:Dnah11	UTSW	12	118,012,272 (GRCm38)	missense	probably damaging	1.00
R9511:Dnah11	UTSW	12	117,914,617 (GRCm38)	missense	probably damaging	1.00
R9526:Dnah11	UTSW	12	118,186,976 (GRCm38)	missense	probably damaging	0.98
R9566:Dnah11	UTSW	12	117,974,993 (GRCm38)	missense	possibly damaging	0.69
R9673:Dnah11	UTSW	12	118,018,778 (GRCm38)	missense	possibly damaging	0.91
R9705:Dnah11	UTSW	12	118,131,035 (GRCm38)	missense	probably damaging	1.00
R9716:Dnah11	UTSW	12	118,060,413 (GRCm38)	missense	probably damaging	0.99
R9746:Dnah11	UTSW	12	117,878,576 (GRCm38)	nonsense	probably null
R9764:Dnah11	UTSW	12	117,920,969 (GRCm38)	missense	probably benign	0.05
RF023:Dnah11	UTSW	12	117,954,850 (GRCm38)	missense	probably damaging	1.00
RF047:Dnah11	UTSW	12	118,010,083 (GRCm38)	missense	probably damaging	1.00
Z1088:Dnah11	UTSW	12	117,895,012 (GRCm38)	missense	probably damaging	1.00
Z1088:Dnah11	UTSW	12	117,982,969 (GRCm38)	missense	probably damaging	1.00
Z1176:Dnah11	UTSW	12	118,130,799 (GRCm38)	missense	probably damaging	0.97
Z1176:Dnah11	UTSW	12	118,127,119 (GRCm38)	missense	probably benign	0.00
Z1176:Dnah11	UTSW	12	117,931,177 (GRCm38)	missense	possibly damaging	0.81

Posted On

2013-04-17