Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL02313:Tex101'

287889

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Tex101

Ensembl Gene

ENSMUSG00000062773

Gene Name

testis expressed gene 101

Synonyms

TES101RP, 1700008H15Rik

Accession Numbers

Is this an essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL02313

Quality Score

Status

Chromosome

Chromosomal Location

24668007-24676675 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 24668325 bp

Zygosity

Heterozygous

Amino Acid Change

Valine to Methionine at position 201 (V201M)

Ref Sequence

ENSEMBL: ENSMUSP00000077150 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000078001] [ENSMUST00000205488] [ENSMUST00000206390]

Predicted Effect

probably damaging
Transcript: ENSMUST00000078001
AA Change: V201M

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000077150
Gene: ENSMUSG00000062773
AA Change: V201M

Domain	Start	End	E-Value	Type
signal peptide	1	25	N/A	INTRINSIC
Pfam:UPAR_LY6	141	217	3.9e-15	PFAM
low complexity region	232	246	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000205488

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000206367

Predicted Effect

probably benign
Transcript: ENSMUST00000206390

Coding Region Coverage

Validation Efficiency

MGI Phenotype

PHENOTYPE: Male mice homozygous for a knockout allele of this marker are infertile due to the failure of sperm to migrate into the oviduct. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 55 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Ankrd13c	T	A	3: 157,947,934	N136K	probably damaging	Het
Aph1b	A	T	9: 66,790,673		probably benign	Het
Atf7ip	A	G	6: 136,606,720	K1250E	probably damaging	Het
Atp8b2	T	C	3: 89,949,853	N400S	probably damaging	Het
Brca2	C	A	5: 150,538,661	S630Y	probably damaging	Het
Chd6	T	A	2: 160,965,675	E1873V	probably damaging	Het
Chrna10	T	C	7: 102,112,029		probably benign	Het
Col6a3	A	G	1: 90,811,606	L907P	probably damaging	Het
Cxcr6	A	G	9: 123,810,705	N264S	probably damaging	Het
Dgkg	A	G	16: 22,570,230		probably benign	Het
Dpysl2	T	G	14: 66,824,390	M256L	probably benign	Het
Dsp	G	T	13: 38,196,523	E1816*	probably null	Het
Fam129c	A	G	8: 71,602,860	R305G	possibly damaging	Het
Fam13b	T	C	18: 34,454,656	K530E	probably damaging	Het
Fam49a	A	G	12: 12,364,751	T248A	possibly damaging	Het
Fastk	T	C	5: 24,443,092	H242R	probably damaging	Het
Fbxw28	A	T	9: 109,337,352	H145Q	possibly damaging	Het
Heatr6	T	C	11: 83,778,892	L910P	probably damaging	Het
Hmcn2	A	G	2: 31,453,605	T4642A	possibly damaging	Het
Hspg2	A	G	4: 137,508,389	T167A	probably benign	Het
Igsf10	A	G	3: 59,330,690	L690P	probably benign	Het
Klhdc10	G	A	6: 30,439,866		probably null	Het
Krt31	A	G	11: 100,048,396	Y232H	probably damaging	Het
Lsm3	A	G	6: 91,516,088		probably benign	Het
Mfn2	T	A	4: 147,885,490	I375F	probably damaging	Het
Mfrp	A	T	9: 44,102,874	I180F	probably damaging	Het
Msh3	T	C	13: 92,349,312	E168G	possibly damaging	Het
Naa16	A	T	14: 79,384,668	V77D	probably damaging	Het
Nav2	T	C	7: 49,558,773	S1570P	probably damaging	Het
Numa1	C	T	7: 102,000,232	R1057*	probably null	Het
Nup210l	G	A	3: 90,122,792	A271T	probably damaging	Het
Ogdh	T	C	11: 6,355,400	V965A	probably damaging	Het
Olfr63	C	A	17: 33,269,665	Q314K	probably benign	Het
Olfr734	A	T	14: 50,320,016	V273E	probably damaging	Het
Olfr818	A	G	10: 129,945,903	L53P	probably damaging	Het
Olfr836	A	T	9: 19,121,375	N140I	probably damaging	Het
Olfr916	T	A	9: 38,658,066	I109F	probably damaging	Het
Pdp2	A	T	8: 104,594,899	Q460L	probably benign	Het
Pex5l	T	C	3: 32,992,992	T270A	probably benign	Het
Pkp4	C	T	2: 59,310,254	Q435*	probably null	Het
Prss32	G	A	17: 23,856,122	V149M	probably benign	Het
Riox2	C	A	16: 59,489,417	P378Q	probably benign	Het
Rita1	C	T	5: 120,609,793	A147T	probably damaging	Het
Rsph4a	T	A	10: 33,905,525	S124T	possibly damaging	Het
Sdccag8	G	A	1: 176,824,755	R24H	possibly damaging	Het
Slc22a1	C	A	17: 12,675,500	G54*	probably null	Het
Slc24a5	C	T	2: 125,085,647		probably benign	Het
Tmprss7	T	C	16: 45,681,593	Y223C	probably damaging	Het
Trpc4ap	T	C	2: 155,650,468	E382G	probably damaging	Het
Uggt1	A	T	1: 36,184,484	Y575N	probably damaging	Het
Vmn2r70	T	C	7: 85,565,168	I259V	probably damaging	Het
Xpo1	T	A	11: 23,277,065	N131K	probably damaging	Het
Zfp579	C	T	7: 4,994,433	V160M	probably benign	Het
Zfp697	A	G	3: 98,425,450	D64G	probably benign	Het
Zfp974	T	C	7: 27,912,253	T16A	possibly damaging	Het

Other mutations in Tex101

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL03007:Tex101	APN	7	24670481	splice site	probably benign
IGL03357:Tex101	APN	7	24668333	missense	probably damaging	0.96
R1935:Tex101	UTSW	7	24668225	missense	probably benign	0.33
R1936:Tex101	UTSW	7	24668225	missense	probably benign	0.33
R4632:Tex101	UTSW	7	24668368	nonsense	probably null
R6109:Tex101	UTSW	7	24668313	missense	possibly damaging	0.79
R7049:Tex101	UTSW	7	24668258	missense	probably benign	0.03
R7276:Tex101	UTSW	7	24670404	missense	probably damaging	1.00
R7860:Tex101	UTSW	7	24669765	missense	probably damaging	1.00
R8092:Tex101	UTSW	7	24670353	missense	probably damaging	1.00
R8435:Tex101	UTSW	7	24668366	missense	probably damaging	1.00
R8514:Tex101	UTSW	7	24668532	missense	possibly damaging	0.87

Posted On

2015-04-16