Incidental Mutation 'IGL02313:Tex101'
ID287889
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Tex101
Ensembl Gene ENSMUSG00000062773
Gene Nametestis expressed gene 101
SynonymsTES101RP, 1700008H15Rik
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL02313
Quality Score
Status
Chromosome7
Chromosomal Location24668007-24676675 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) C to T at 24668325 bp
ZygosityHeterozygous
Amino Acid Change Valine to Methionine at position 201 (V201M)
Ref Sequence ENSEMBL: ENSMUSP00000077150 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000078001] [ENSMUST00000205488] [ENSMUST00000206390]
Predicted Effect probably damaging
Transcript: ENSMUST00000078001
AA Change: V201M

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000077150
Gene: ENSMUSG00000062773
AA Change: V201M

DomainStartEndE-ValueType
signal peptide 1 25 N/A INTRINSIC
Pfam:UPAR_LY6 141 217 3.9e-15 PFAM
low complexity region 232 246 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000205488
Predicted Effect noncoding transcript
Transcript: ENSMUST00000206367
Predicted Effect probably benign
Transcript: ENSMUST00000206390
Coding Region Coverage
Validation Efficiency
MGI Phenotype PHENOTYPE: Male mice homozygous for a knockout allele of this marker are infertile due to the failure of sperm to migrate into the oviduct. [provided by MGI curators]
Allele List at MGI
Other mutations in this stock
Total: 55 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Ankrd13c T A 3: 157,947,934 N136K probably damaging Het
Aph1b A T 9: 66,790,673 probably benign Het
Atf7ip A G 6: 136,606,720 K1250E probably damaging Het
Atp8b2 T C 3: 89,949,853 N400S probably damaging Het
Brca2 C A 5: 150,538,661 S630Y probably damaging Het
Chd6 T A 2: 160,965,675 E1873V probably damaging Het
Chrna10 T C 7: 102,112,029 probably benign Het
Col6a3 A G 1: 90,811,606 L907P probably damaging Het
Cxcr6 A G 9: 123,810,705 N264S probably damaging Het
Dgkg A G 16: 22,570,230 probably benign Het
Dpysl2 T G 14: 66,824,390 M256L probably benign Het
Dsp G T 13: 38,196,523 E1816* probably null Het
Fam129c A G 8: 71,602,860 R305G possibly damaging Het
Fam13b T C 18: 34,454,656 K530E probably damaging Het
Fam49a A G 12: 12,364,751 T248A possibly damaging Het
Fastk T C 5: 24,443,092 H242R probably damaging Het
Fbxw28 A T 9: 109,337,352 H145Q possibly damaging Het
Heatr6 T C 11: 83,778,892 L910P probably damaging Het
Hmcn2 A G 2: 31,453,605 T4642A possibly damaging Het
Hspg2 A G 4: 137,508,389 T167A probably benign Het
Igsf10 A G 3: 59,330,690 L690P probably benign Het
Klhdc10 G A 6: 30,439,866 probably null Het
Krt31 A G 11: 100,048,396 Y232H probably damaging Het
Lsm3 A G 6: 91,516,088 probably benign Het
Mfn2 T A 4: 147,885,490 I375F probably damaging Het
Mfrp A T 9: 44,102,874 I180F probably damaging Het
Msh3 T C 13: 92,349,312 E168G possibly damaging Het
Naa16 A T 14: 79,384,668 V77D probably damaging Het
Nav2 T C 7: 49,558,773 S1570P probably damaging Het
Numa1 C T 7: 102,000,232 R1057* probably null Het
Nup210l G A 3: 90,122,792 A271T probably damaging Het
Ogdh T C 11: 6,355,400 V965A probably damaging Het
Olfr63 C A 17: 33,269,665 Q314K probably benign Het
Olfr734 A T 14: 50,320,016 V273E probably damaging Het
Olfr818 A G 10: 129,945,903 L53P probably damaging Het
Olfr836 A T 9: 19,121,375 N140I probably damaging Het
Olfr916 T A 9: 38,658,066 I109F probably damaging Het
Pdp2 A T 8: 104,594,899 Q460L probably benign Het
Pex5l T C 3: 32,992,992 T270A probably benign Het
Pkp4 C T 2: 59,310,254 Q435* probably null Het
Prss32 G A 17: 23,856,122 V149M probably benign Het
Riox2 C A 16: 59,489,417 P378Q probably benign Het
Rita1 C T 5: 120,609,793 A147T probably damaging Het
Rsph4a T A 10: 33,905,525 S124T possibly damaging Het
Sdccag8 G A 1: 176,824,755 R24H possibly damaging Het
Slc22a1 C A 17: 12,675,500 G54* probably null Het
Slc24a5 C T 2: 125,085,647 probably benign Het
Tmprss7 T C 16: 45,681,593 Y223C probably damaging Het
Trpc4ap T C 2: 155,650,468 E382G probably damaging Het
Uggt1 A T 1: 36,184,484 Y575N probably damaging Het
Vmn2r70 T C 7: 85,565,168 I259V probably damaging Het
Xpo1 T A 11: 23,277,065 N131K probably damaging Het
Zfp579 C T 7: 4,994,433 V160M probably benign Het
Zfp697 A G 3: 98,425,450 D64G probably benign Het
Zfp974 T C 7: 27,912,253 T16A possibly damaging Het
Other mutations in Tex101
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL03007:Tex101 APN 7 24670481 splice site probably benign
IGL03357:Tex101 APN 7 24668333 missense probably damaging 0.96
R1935:Tex101 UTSW 7 24668225 missense probably benign 0.33
R1936:Tex101 UTSW 7 24668225 missense probably benign 0.33
R4632:Tex101 UTSW 7 24668368 nonsense probably null
R6109:Tex101 UTSW 7 24668313 missense possibly damaging 0.79
R7049:Tex101 UTSW 7 24668258 missense probably benign 0.03
R7276:Tex101 UTSW 7 24670404 missense probably damaging 1.00
R7860:Tex101 UTSW 7 24669765 missense probably damaging 1.00
R7943:Tex101 UTSW 7 24669765 missense probably damaging 1.00
Posted On2015-04-16