Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL02314:Gm2035'

287942

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm2035

Ensembl Gene

ENSMUSG00000096619

Gene Name

predicted pseudogene 2035

Synonyms

Accession Numbers

Is this an essential gene?

Possibly non essential (E-score: 0.320) question?

Stock #

IGL02314

Quality Score

Status

Chromosome

Chromosomal Location

87919423-87919857 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 87919607 bp

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Phenylalanine at position 84 (Y84F)

Ref Sequence

ENSEMBL: ENSMUSP00000137146 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000180053]

Predicted Effect

probably benign
Transcript: ENSMUST00000180053
AA Change: Y84F

PolyPhen 2 Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)

SMART Domains

Protein: ENSMUSP00000137146
Gene: ENSMUSG00000096619
AA Change: Y84F

Domain	Start	End	E-Value	Type
low complexity region	3	25	N/A	INTRINSIC
eIF1a	28	110	4.13e-45	SMART
low complexity region	125	144	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 64 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Alg2	T	A	4: 47,472,143	K94*	probably null	Het
Axl	A	G	7: 25,786,920	F120L	possibly damaging	Het
Baz2b	A	G	2: 59,962,227	V519A	probably benign	Het
Cdk2	A	T	10: 128,703,726	I99N	probably damaging	Het
Ces1b	C	A	8: 93,064,896	W358C	possibly damaging	Het
Clca3b	A	G	3: 144,828,142		probably benign	Het
Col6a4	T	G	9: 105,997,156	T2211P	probably damaging	Het
Cyp4f14	C	T	17: 32,906,291	E438K	probably benign	Het
Dpy19l4	T	A	4: 11,267,720	T407S	possibly damaging	Het
Dtx3	G	A	10: 127,190,959		probably benign	Het
Fat3	A	T	9: 15,969,838	L3246H	possibly damaging	Het
Fat4	A	T	3: 38,887,630	D224V	probably damaging	Het
Fndc9	A	T	11: 46,238,295	I214F	probably benign	Het
Foxred1	A	T	9: 35,205,968	I22N	probably damaging	Het
Gkn1	T	C	6: 87,349,121	D29G	probably benign	Het
Gm13078	T	C	4: 143,728,442	S437P	probably benign	Het
Gng11	T	A	6: 4,004,317	M1K	probably null	Het
Hdac7	T	C	15: 97,809,004	D237G	probably damaging	Het
Hgf	A	G	5: 16,572,602	Y199C	probably damaging	Het
Hgfac	A	T	5: 35,041,597	M1L	probably benign	Het
Hsd17b6	T	C	10: 127,997,908	T35A	probably damaging	Het
Htr3a	G	A	9: 48,904,627	P170L	probably damaging	Het
Ighv12-3	A	G	12: 114,366,801	S25P	probably damaging	Het
Jph2	A	T	2: 163,397,353	N58K	probably damaging	Het
Lama5	A	G	2: 180,194,482		probably benign	Het
Lpin3	T	A	2: 160,898,718	Y394*	probably null	Het
Macf1	G	T	4: 123,444,837	T2248K	probably damaging	Het
Map3k2	A	G	18: 32,218,500		probably benign	Het
Map4k5	G	A	12: 69,818,439	P524S	probably benign	Het
Mcf2l	C	T	8: 13,001,851	S359L	probably damaging	Het
Mdh1b	C	T	1: 63,711,114		probably null	Het
Mfhas1	G	A	8: 35,588,773	R134H	probably damaging	Het
Mogs	A	G	6: 83,118,055	T618A	probably benign	Het
Mybpc2	T	A	7: 44,522,388	Q39H	possibly damaging	Het
Myoc	C	T	1: 162,639,348	R29W	probably damaging	Het
Nae1	A	G	8: 104,526,306	M162T	probably damaging	Het
Nfatc3	A	G	8: 106,078,900	I126V	probably benign	Het
Nxnl2	C	A	13: 51,171,529	F69L	probably benign	Het
Oca2	T	A	7: 56,357,151	I662N	probably benign	Het
Odf3b	T	G	15: 89,378,169	K82N	probably damaging	Het
Olfr1151	A	G	2: 87,858,056	N294D	probably damaging	Het
Olfr1356	A	T	10: 78,847,265	S217T	probably damaging	Het
Olfr549	A	T	7: 102,555,111	I276F	probably damaging	Het
Olfr872	A	T	9: 20,260,478	I213L	probably benign	Het
Pcdhb14	G	A	18: 37,450,195	E785K	probably benign	Het
Plb1	A	C	5: 32,281,148	Y209S	possibly damaging	Het
Rab44	C	A	17: 29,139,353	Q172K	probably benign	Het
Rnf214	A	T	9: 45,899,807	V186E	probably benign	Het
Rps6ka1	C	A	4: 133,850,754	G522W	probably damaging	Het
Samhd1	G	T	2: 157,135,028	T21K	probably damaging	Het
Scly	A	G	1: 91,319,041	Y358C	probably benign	Het
Sfxn2	A	G	19: 46,582,587	N29D	possibly damaging	Het
Shank2	A	G	7: 144,411,271	D1451G	probably benign	Het
Slc44a5	G	A	3: 154,256,519	S363N	probably damaging	Het
Smg1	A	G	7: 118,154,709		probably benign	Het
Tas1r3	A	T	4: 155,860,662	C701S	probably damaging	Het
Tmem87a	A	G	2: 120,404,021	S14P	possibly damaging	Het
Trmt6	G	A	2: 132,805,458	A486V	probably benign	Het
Ttn	G	A	2: 76,896,747	R1602*	probably null	Het
Ush2a	A	G	1: 188,633,629	M2227V	probably benign	Het
Vmn2r96	A	T	17: 18,583,959	Q490H	probably benign	Het
Wdr19	G	T	5: 65,257,120	A1279S	probably benign	Het
Zbtb7c	G	A	18: 76,145,866	R465H	probably damaging	Het
Zfp473	T	C	7: 44,733,929	S326G	probably benign	Het

Other mutations in Gm2035

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02347:Gm2035	APN	12	87919589	missense	probably damaging	1.00
IGL02639:Gm2035	APN	12	87919499	missense	probably benign	0.04
R4230:Gm2035	UTSW	12	87919797	missense	unknown
R5969:Gm2035	UTSW	12	87919478	missense	unknown
R6159:Gm2035	UTSW	12	87919751	missense	probably damaging	1.00
R6359:Gm2035	UTSW	12	87919505	missense	probably benign	0.09
R7181:Gm2035	UTSW	12	87919722	missense	possibly damaging	0.49
R7183:Gm2035	UTSW	12	87919722	missense	possibly damaging	0.49
R7184:Gm2035	UTSW	12	87919722	missense	possibly damaging	0.49
R7653:Gm2035	UTSW	12	87919478	missense	unknown
R8046:Gm2035	UTSW	12	87919565	missense	probably benign	0.02
R8353:Gm2035	UTSW	12	87919553	missense	probably benign
R8453:Gm2035	UTSW	12	87919553	missense	probably benign

Posted On

2015-04-16