Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02329:Trcg1'

288609

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Trcg1

Ensembl Gene

ENSMUSG00000070298

Gene Name

taste receptor cell gene 1

Synonyms

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.063) question?

Stock #

IGL02329

Quality Score

Status

Chromosome

Chromosomal Location

57236556-57249864 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 57240393 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Phenylalanine at position 11 (I11F)

Ref Sequence

ENSEMBL: ENSMUSP00000091357 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000093837]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000093837
AA Change: I11F

PolyPhen 2 Score 0.915 (Sensitivity: 0.81; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000091357
Gene: ENSMUSG00000070298
AA Change: I11F

Domain	Start	End	E-Value	Type
signal peptide	1	21	N/A	INTRINSIC
low complexity region	302	335	N/A	INTRINSIC
Blast:SEA	449	549	5e-21	BLAST
low complexity region	580	594	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 32 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700016C15Rik	A	T	1: 177,743,301	Q67L	probably benign	Het
Atg2a	T	C	19: 6,249,929		probably null	Het
Bfsp1	T	C	2: 143,862,646	T96A	probably benign	Het
Btnl1	A	G	17: 34,382,265	E322G	possibly damaging	Het
Cand2	T	C	6: 115,789,607	V391A	probably damaging	Het
Ccdc169	A	G	3: 55,171,281	M188V	probably benign	Het
Cngb1	T	C	8: 95,242,359	I1174V	probably benign	Het
Cpeb4	T	C	11: 31,872,316	V10A	possibly damaging	Het
Cpt1b	T	C	15: 89,423,739	T206A	probably benign	Het
Dapk3	T	C	10: 81,190,165	S97P	probably benign	Het
Drc3	T	C	11: 60,370,578	L185P	probably damaging	Het
Efr3b	T	C	12: 3,992,923		probably null	Het
Erbb3	T	A	10: 128,573,219	I742F	probably damaging	Het
Fktn	A	G	4: 53,720,181	Y65C	probably benign	Het
Fstl5	G	A	3: 76,588,995	G355D	probably damaging	Het
Grm8	A	T	6: 27,363,116	I800N	probably damaging	Het
Gss	C	T	2: 155,567,853	R221H	probably benign	Het
H2-M10.4	A	T	17: 36,460,467	V273D	probably damaging	Het
Large1	C	A	8: 73,048,317	W255L	possibly damaging	Het
Meig1	T	C	2: 3,409,251	K71E	probably damaging	Het
Mtor	A	G	4: 148,534,939	N1760D	probably benign	Het
Ncapd2	A	T	6: 125,189,818	N24K	probably damaging	Het
Nphp3	A	C	9: 104,025,968	S715R	probably benign	Het
Papolg	T	G	11: 23,891,869	H18P	probably damaging	Het
Psd	T	C	19: 46,319,659	H667R	possibly damaging	Het
Rita1	C	T	5: 120,609,793	A147T	probably damaging	Het
Rtp1	T	C	16: 23,431,193	S103P	probably damaging	Het
Snx21	T	C	2: 164,792,390		probably benign	Het
Tiam1	G	T	16: 89,800,036	H301N	probably benign	Het
Trpm6	A	G	19: 18,854,217	K1482R	probably benign	Het
Tyw1	G	T	5: 130,267,080	G116V	probably benign	Het
Zfp341	T	C	2: 154,632,304	C343R	possibly damaging	Het

Other mutations in Trcg1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01727:Trcg1	APN	9	57242273	missense	probably benign
IGL01727:Trcg1	APN	9	57242594	missense	probably damaging	0.97
IGL02147:Trcg1	APN	9	57245849	missense	probably benign	0.20
IGL02658:Trcg1	APN	9	57242228	nonsense	probably null
IGL02852:Trcg1	APN	9	57241312	missense	possibly damaging	0.94
IGL03163:Trcg1	APN	9	57248347	missense	possibly damaging	0.92
FR4589:Trcg1	UTSW	9	57242202	frame shift	probably null
R0555:Trcg1	UTSW	9	57242333	missense	probably damaging	1.00
R0747:Trcg1	UTSW	9	57241921	missense	probably benign	0.00
R1061:Trcg1	UTSW	9	57245873	missense	possibly damaging	0.66
R1521:Trcg1	UTSW	9	57242465	missense	probably benign	0.36
R1622:Trcg1	UTSW	9	57248672	missense	possibly damaging	0.94
R1652:Trcg1	UTSW	9	57245573	missense	probably damaging	0.99
R4677:Trcg1	UTSW	9	57245861	missense	possibly damaging	0.94
R4879:Trcg1	UTSW	9	57246720	missense	probably damaging	0.99
R5013:Trcg1	UTSW	9	57242279	missense	probably damaging	0.99
R5141:Trcg1	UTSW	9	57241304	missense	probably damaging	1.00
R5690:Trcg1	UTSW	9	57241811	missense	probably benign	0.36
R6416:Trcg1	UTSW	9	57241330	missense	possibly damaging	0.46
R6980:Trcg1	UTSW	9	57245573	missense	probably damaging	0.99
R7022:Trcg1	UTSW	9	57241569	missense	possibly damaging	0.46
R7172:Trcg1	UTSW	9	57248335	missense	probably benign	0.01
R7276:Trcg1	UTSW	9	57242579	missense	probably damaging	0.99
R7412:Trcg1	UTSW	9	57241483	missense	probably benign	0.00
R7546:Trcg1	UTSW	9	57248338	missense	probably benign	0.34
R7942:Trcg1	UTSW	9	57242216	missense	probably benign
R8087:Trcg1	UTSW	9	57248674	missense	probably damaging	0.99
R8094:Trcg1	UTSW	9	57242281	missense	probably benign	0.01
R8825:Trcg1	UTSW	9	57241471	missense	probably benign	0.19

Posted On

2015-04-16