Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL02333:Vmn2r32'

288775

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r32

Ensembl Gene

Gene Name

vomeronasal 2, receptor 32

Synonyms

V2r5

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.144) question?

Stock #

IGL02333

Quality Score

Status

Chromosome

Chromosomal Location

7463015-7479973 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 7464144 bp

Zygosity

Heterozygous

Amino Acid Change

Phenylalanine to Tyrosine at position 795 (F795Y)

Ref Sequence

ENSEMBL: ENSMUSP00000092462 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000094866]

Predicted Effect

probably damaging
Transcript: ENSMUST00000094866
AA Change: F795Y

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000092462
Gene: ENSMUSG00000096743
AA Change: F795Y

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC
Pfam:ANF_receptor	73	470	3.6e-33	PFAM
Pfam:NCD3G	512	565	8.1e-21	PFAM
Pfam:7tm_3	598	833	9.5e-55	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 25 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Ace	G	A	11: 105,971,447	V276I	probably benign	Het
Acss2	T	A	2: 155,555,884	W289R	probably damaging	Het
Alpk2	A	G	18: 65,349,480	S19P	probably damaging	Het
Ano3	T	C	2: 110,697,199		probably benign	Het
Atxn1	G	A	13: 45,567,204	S405F	probably damaging	Het
Atxn2	A	G	5: 121,781,387	Y386C	probably damaging	Het
Bach2	T	A	4: 32,575,334	L643*	probably null	Het
Ccl22	T	A	8: 94,749,879	L91Q	probably damaging	Het
Cdc40	A	G	10: 40,867,859	Y81H	probably benign	Het
Col5a3	C	A	9: 20,799,306	R549M	unknown	Het
Eif3e	A	T	15: 43,266,137	N198K	probably benign	Het
Emp2	A	G	16: 10,284,511	Y146H	probably damaging	Het
Impg1	G	A	9: 80,440,755	L66F	possibly damaging	Het
Itsn1	A	G	16: 91,820,676		probably benign	Het
Khdrbs3	T	C	15: 69,049,394	Y187H	probably damaging	Het
Klhdc7a	T	A	4: 139,967,156	H160L	probably benign	Het
Klhl2	G	A	8: 64,759,750	R252W	probably damaging	Het
Krba1	C	T	6: 48,413,087	T595I	probably damaging	Het
Myo9b	G	T	8: 71,358,993	D1887Y	possibly damaging	Het
Olfm4	C	T	14: 80,021,770	T453I	probably damaging	Het
Sin3a	A	G	9: 57,107,559	N688S	possibly damaging	Het
Slc47a1	A	G	11: 61,370,124	V150A	probably damaging	Het
Sptbn4	A	G	7: 27,364,299	L2234P	probably damaging	Het
Trpm4	C	T	7: 45,322,115	V166M	possibly damaging	Het
Usp54	A	T	14: 20,589,395	F156L	probably damaging	Het

Other mutations in Vmn2r32

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02140:Vmn2r32	APN	7	7476697	missense	probably damaging	0.97
IGL02406:Vmn2r32	APN	7	7476710	missense	probably benign
IGL02428:Vmn2r32	APN	7	7474284	missense	probably benign	0.02
IGL02484:Vmn2r32	APN	7	7464117	missense	probably damaging	1.00
IGL03277:Vmn2r32	APN	7	7474252	missense	probably benign	0.23
IGL03366:Vmn2r32	APN	7	7464030	missense	probably damaging	0.99
R1055:Vmn2r32	UTSW	7	7474327	nonsense	probably null
R1695:Vmn2r32	UTSW	7	7463992	missense	probably benign	0.01
R2172:Vmn2r32	UTSW	7	7474615	missense	probably damaging	0.99
R2262:Vmn2r32	UTSW	7	7474619	missense	probably benign
R3150:Vmn2r32	UTSW	7	7472555	missense	probably benign
R4362:Vmn2r32	UTSW	7	7479858	nonsense	probably null
R4432:Vmn2r32	UTSW	7	7479919	missense	probably damaging	0.98
R4851:Vmn2r32	UTSW	7	7479954	missense	possibly damaging	0.59
R4949:Vmn2r32	UTSW	7	7464084	missense	probably benign	0.22
R5990:Vmn2r32	UTSW	7	7479810	missense	probably damaging	0.97
R6083:Vmn2r32	UTSW	7	7464210	missense	probably benign	0.15
R6084:Vmn2r32	UTSW	7	7464210	missense	probably benign	0.15
R6116:Vmn2r32	UTSW	7	7464093	missense	probably damaging	1.00
R6263:Vmn2r32	UTSW	7	7476692	missense	possibly damaging	0.90
R6889:Vmn2r32	UTSW	7	7472574	missense	possibly damaging	0.82
R7286:Vmn2r32	UTSW	7	7479808	missense	probably benign	0.21
R7390:Vmn2r32	UTSW	7	7479852	missense	probably benign	0.00
R7412:Vmn2r32	UTSW	7	7474213	missense	possibly damaging	0.53
R7508:Vmn2r32	UTSW	7	7467374	missense	possibly damaging	0.87
Z1177:Vmn2r32	UTSW	7	7474161	missense	probably damaging	0.98

Posted On

2015-04-16