Incidental Mutation 'IGL02338:Stk-ps2'
ID288951
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Stk-ps2
Ensembl Gene ENSMUSG00000044457
Gene Nameserine/threonine kinase 2
SynonymsGm4776
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.094) question?
Stock #IGL02338
Quality Score
Status
Chromosome1
Chromosomal Location46020072-46030469 bp(-) (GRCm38)
Type of Mutationexon
DNA Base Change (assembly) T to A at 46030177 bp
ZygosityHeterozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s):
Predicted Effect noncoding transcript
Transcript: ENSMUST00000051224
SMART Domains Protein: ENSMUSP00000054781
Gene: ENSMUSG00000044457

DomainStartEndE-ValueType
S_TKc 14 262 5.9e-85 SMART
UBA 276 313 8.44e-4 SMART
low complexity region 335 349 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000167676
SMART Domains Protein: ENSMUSP00000133145
Gene: ENSMUSG00000044457

DomainStartEndE-ValueType
S_TKc 14 262 5.9e-85 SMART
UBA 276 313 8.44e-4 SMART
low complexity region 335 349 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000171707
SMART Domains Protein: ENSMUSP00000125766
Gene: ENSMUSG00000044457

DomainStartEndE-ValueType
S_TKc 14 262 5.9e-85 SMART
UBA 276 313 8.44e-4 SMART
low complexity region 335 349 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000187808
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 63 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Ahdc1 G A 4: 133,062,549 C367Y possibly damaging Het
AI182371 T A 2: 35,085,716 I279L probably benign Het
Ambp A T 4: 63,143,697 C332S probably damaging Het
App T C 16: 85,173,519 T14A probably benign Het
Asap1 A T 15: 64,123,670 probably null Het
Aurka T C 2: 172,359,858 R242G probably benign Het
BC034090 G A 1: 155,217,471 P747L probably damaging Het
Bcl6b T C 11: 70,229,092 D23G probably damaging Het
Cabp2 A C 19: 4,084,154 E42A possibly damaging Het
Ccdc14 G A 16: 34,721,803 S557N probably benign Het
Ccdc146 G T 5: 21,319,606 probably benign Het
Cenpf T A 1: 189,680,418 Q216L probably damaging Het
Ces1b G A 8: 93,057,047 P515L possibly damaging Het
Col6a5 A T 9: 105,878,630 N2198K probably damaging Het
Csmd2 A G 4: 128,395,066 S1133G possibly damaging Het
Cspg5 G A 9: 110,256,267 R502H probably benign Het
Cyp2g1 A G 7: 26,814,804 probably benign Het
Dnajc27 A G 12: 4,096,229 Y86C probably damaging Het
Dnm1 T C 2: 32,312,771 D715G probably damaging Het
Dock1 G T 7: 135,133,075 L1317F possibly damaging Het
Fanci T A 7: 79,433,531 Y727* probably null Het
Fbxw20 T A 9: 109,225,978 T168S probably benign Het
Folh1 A T 7: 86,736,515 probably benign Het
Gas7 A T 11: 67,682,731 S379C probably damaging Het
Gbp2b A G 3: 142,604,226 E259G probably benign Het
Gm8325 T C 3: 60,877,384 noncoding transcript Het
Gm9268 T C 7: 43,047,736 I739T probably damaging Het
Gpr75 A T 11: 30,891,730 T212S probably benign Het
Itgb4 A G 11: 116,007,969 T1711A probably damaging Het
Ly75 T C 2: 60,354,452 S453G probably benign Het
Maneal A G 4: 124,860,483 probably benign Het
Marco A T 1: 120,494,779 I58N possibly damaging Het
Mtcl1 A G 17: 66,379,970 I647T probably damaging Het
Mtfr1l A T 4: 134,530,743 V56D probably damaging Het
Npy1r G A 8: 66,704,302 V125I probably damaging Het
Olfr348 C T 2: 36,786,545 Q7* probably null Het
Olfr659 T C 7: 104,671,681 probably benign Het
Olfr843 A G 9: 19,248,664 L245P probably damaging Het
Osmr A T 15: 6,837,729 L362* probably null Het
Pdlim2 T C 14: 70,174,457 D42G probably damaging Het
Plcb4 T A 2: 136,000,180 I89N possibly damaging Het
Prrc2b T A 2: 32,214,035 M1175K probably benign Het
Pzp T A 6: 128,486,170 N1423I probably benign Het
Retnla G A 16: 48,844,198 C105Y probably damaging Het
Samd8 T A 14: 21,775,476 S167T possibly damaging Het
Scg2 A G 1: 79,436,493 M171T possibly damaging Het
Slc30a5 A G 13: 100,803,433 V658A probably damaging Het
Slc41a2 T C 10: 83,316,591 R7G possibly damaging Het
Slc44a2 A G 9: 21,347,042 T500A probably damaging Het
Slc44a4 G T 17: 34,923,810 G396V possibly damaging Het
Smarca5 A G 8: 80,719,570 probably benign Het
St8sia6 T A 2: 13,793,345 R34W probably damaging Het
Stn1 T C 19: 47,513,890 Y235C probably damaging Het
Tbx15 A G 3: 99,352,484 Y557C probably damaging Het
Tgfbr1 G A 4: 47,393,490 probably null Het
Thsd7b G T 1: 129,595,771 V181L probably damaging Het
Tmpo G A 10: 91,163,242 R228C probably benign Het
Trpm4 T G 7: 45,326,998 R51S probably damaging Het
Vmn1r91 A T 7: 20,101,746 T197S probably damaging Het
Xrn1 A G 9: 95,977,827 D424G probably benign Het
Yap1 A G 9: 7,962,281 probably null Het
Zer1 T C 2: 30,113,393 D4G probably damaging Het
Zfp462 A T 4: 55,010,292 I753F possibly damaging Het
Other mutations in Stk-ps2
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01088:Stk-ps2 APN 1 46029850 exon noncoding transcript
IGL01662:Stk-ps2 APN 1 46029362 unclassified noncoding transcript
IGL01859:Stk-ps2 APN 1 46030042 exon noncoding transcript
IGL01949:Stk-ps2 APN 1 46029988 exon noncoding transcript
R0087:Stk-ps2 UTSW 1 46029889 exon noncoding transcript
R0139:Stk-ps2 UTSW 1 46029795 exon noncoding transcript
R0627:Stk-ps2 UTSW 1 46029691 exon noncoding transcript
R3086:Stk-ps2 UTSW 1 46029076 unclassified noncoding transcript
R3763:Stk-ps2 UTSW 1 46029921 exon noncoding transcript
R4817:Stk-ps2 UTSW 1 46028965 unclassified noncoding transcript
R4951:Stk-ps2 UTSW 1 46029442 unclassified noncoding transcript
Posted On2015-04-16