Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02338:Cyp2g1'

288973

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Cyp2g1

Ensembl Gene

ENSMUSG00000049685

Gene Name

cytochrome P450, family 2, subfamily g, polypeptide 1

Synonyms

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL02338

Quality Score

Status

Chromosome

Chromosomal Location

26808892-26821205 bp(+) (GRCm38)

Type of Mutation

splice site

DNA Base Change (assembly)

A to G at 26814804 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000047150 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000040944]

AlphaFold

Q9WV19

Predicted Effect

probably benign
Transcript: ENSMUST00000040944

SMART Domains

Protein: ENSMUSP00000047150
Gene: ENSMUSG00000049685

Domain	Start	End	E-Value	Type
low complexity region	12	23	N/A	INTRINSIC
Pfam:p450	34	491	4e-150	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000205273

Coding Region Coverage

Validation Efficiency

MGI Phenotype

PHENOTYPE: Mice homozygous for disruptions in this gene display an essentially normal phenotype. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 63 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Ahdc1	G	A	4: 133,062,549	C367Y	possibly damaging	Het
AI182371	T	A	2: 35,085,716	I279L	probably benign	Het
Ambp	A	T	4: 63,143,697	C332S	probably damaging	Het
App	T	C	16: 85,173,519	T14A	probably benign	Het
Asap1	A	T	15: 64,123,670		probably null	Het
Aurka	T	C	2: 172,359,858	R242G	probably benign	Het
BC034090	G	A	1: 155,217,471	P747L	probably damaging	Het
Bcl6b	T	C	11: 70,229,092	D23G	probably damaging	Het
Cabp2	A	C	19: 4,084,154	E42A	possibly damaging	Het
Ccdc14	G	A	16: 34,721,803	S557N	probably benign	Het
Ccdc146	G	T	5: 21,319,606		probably benign	Het
Cenpf	T	A	1: 189,680,418	Q216L	probably damaging	Het
Ces1b	G	A	8: 93,057,047	P515L	possibly damaging	Het
Col6a5	A	T	9: 105,878,630	N2198K	probably damaging	Het
Csmd2	A	G	4: 128,395,066	S1133G	possibly damaging	Het
Cspg5	G	A	9: 110,256,267	R502H	probably benign	Het
Dnajc27	A	G	12: 4,096,229	Y86C	probably damaging	Het
Dnm1	T	C	2: 32,312,771	D715G	probably damaging	Het
Dock1	G	T	7: 135,133,075	L1317F	possibly damaging	Het
Fanci	T	A	7: 79,433,531	Y727*	probably null	Het
Fbxw20	T	A	9: 109,225,978	T168S	probably benign	Het
Folh1	A	T	7: 86,736,515		probably benign	Het
Gas7	A	T	11: 67,682,731	S379C	probably damaging	Het
Gbp2b	A	G	3: 142,604,226	E259G	probably benign	Het
Gm8325	T	C	3: 60,877,384		noncoding transcript	Het
Gm9268	T	C	7: 43,047,736	I739T	probably damaging	Het
Gpr75	A	T	11: 30,891,730	T212S	probably benign	Het
Itgb4	A	G	11: 116,007,969	T1711A	probably damaging	Het
Ly75	T	C	2: 60,354,452	S453G	probably benign	Het
Maneal	A	G	4: 124,860,483		probably benign	Het
Marco	A	T	1: 120,494,779	I58N	possibly damaging	Het
Mtcl1	A	G	17: 66,379,970	I647T	probably damaging	Het
Mtfr1l	A	T	4: 134,530,743	V56D	probably damaging	Het
Npy1r	G	A	8: 66,704,302	V125I	probably damaging	Het
Olfr348	C	T	2: 36,786,545	Q7*	probably null	Het
Olfr659	T	C	7: 104,671,681		probably benign	Het
Olfr843	A	G	9: 19,248,664	L245P	probably damaging	Het
Osmr	A	T	15: 6,837,729	L362*	probably null	Het
Pdlim2	T	C	14: 70,174,457	D42G	probably damaging	Het
Plcb4	T	A	2: 136,000,180	I89N	possibly damaging	Het
Prrc2b	T	A	2: 32,214,035	M1175K	probably benign	Het
Pzp	T	A	6: 128,486,170	N1423I	probably benign	Het
Retnla	G	A	16: 48,844,198	C105Y	probably damaging	Het
Samd8	T	A	14: 21,775,476	S167T	possibly damaging	Het
Scg2	A	G	1: 79,436,493	M171T	possibly damaging	Het
Slc30a5	A	G	13: 100,803,433	V658A	probably damaging	Het
Slc41a2	T	C	10: 83,316,591	R7G	possibly damaging	Het
Slc44a2	A	G	9: 21,347,042	T500A	probably damaging	Het
Slc44a4	G	T	17: 34,923,810	G396V	possibly damaging	Het
Smarca5	A	G	8: 80,719,570		probably benign	Het
St8sia6	T	A	2: 13,793,345	R34W	probably damaging	Het
Stk-ps2	T	A	1: 46,030,177		noncoding transcript	Het
Stn1	T	C	19: 47,513,890	Y235C	probably damaging	Het
Tbx15	A	G	3: 99,352,484	Y557C	probably damaging	Het
Tgfbr1	G	A	4: 47,393,490		probably null	Het
Thsd7b	G	T	1: 129,595,771	V181L	probably damaging	Het
Tmpo	G	A	10: 91,163,242	R228C	probably benign	Het
Trpm4	T	G	7: 45,326,998	R51S	probably damaging	Het
Vmn1r91	A	T	7: 20,101,746	T197S	probably damaging	Het
Xrn1	A	G	9: 95,977,827	D424G	probably benign	Het
Yap1	A	G	9: 7,962,281		probably null	Het
Zer1	T	C	2: 30,113,393	D4G	probably damaging	Het
Zfp462	A	T	4: 55,010,292	I753F	possibly damaging	Het

Other mutations in Cyp2g1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01134:Cyp2g1	APN	7	26809831	missense	probably benign	0.05
IGL01137:Cyp2g1	APN	7	26814259	missense	possibly damaging	0.87
IGL02052:Cyp2g1	APN	7	26814294	splice site	probably benign
IGL02452:Cyp2g1	APN	7	26811446	missense	probably benign	0.28
IGL02523:Cyp2g1	APN	7	26819187	missense	probably damaging	1.00
IGL03165:Cyp2g1	APN	7	26809776	missense	possibly damaging	0.94
IGL03230:Cyp2g1	APN	7	26819403	missense	probably damaging	1.00
PIT4472001:Cyp2g1	UTSW	7	26814194	missense	probably benign	0.28
R0106:Cyp2g1	UTSW	7	26814182	missense	probably damaging	1.00
R0106:Cyp2g1	UTSW	7	26814182	missense	probably damaging	1.00
R0380:Cyp2g1	UTSW	7	26814295	splice site	probably benign
R0697:Cyp2g1	UTSW	7	26814727	nonsense	probably null
R0830:Cyp2g1	UTSW	7	26814791	missense	probably benign	0.00
R1660:Cyp2g1	UTSW	7	26809682	critical splice acceptor site	probably null
R2093:Cyp2g1	UTSW	7	26819433	missense	probably benign	0.35
R2131:Cyp2g1	UTSW	7	26820710	missense	probably damaging	0.99
R4606:Cyp2g1	UTSW	7	26814154	missense	possibly damaging	0.80
R5030:Cyp2g1	UTSW	7	26820801	missense	probably benign	0.06
R5574:Cyp2g1	UTSW	7	26820740	missense	possibly damaging	0.81
R5877:Cyp2g1	UTSW	7	26816640	missense	possibly damaging	0.80
R6745:Cyp2g1	UTSW	7	26814179	missense	probably damaging	1.00
R7040:Cyp2g1	UTSW	7	26820759	missense	probably damaging	0.99
R7223:Cyp2g1	UTSW	7	26814632	missense	probably damaging	0.98
R7934:Cyp2g1	UTSW	7	26819193	missense	probably damaging	1.00
R8112:Cyp2g1	UTSW	7	26819461	missense	probably benign
R8177:Cyp2g1	UTSW	7	26819153	missense	probably damaging	1.00
R8194:Cyp2g1	UTSW	7	26814734	missense	possibly damaging	0.89
R9043:Cyp2g1	UTSW	7	26809831	missense	probably benign	0.05
R9406:Cyp2g1	UTSW	7	26819485	critical splice donor site	probably null
R9441:Cyp2g1	UTSW	7	26814635	missense	possibly damaging	0.72
X0067:Cyp2g1	UTSW	7	26820762	missense	possibly damaging	0.70

Posted On

2015-04-16