Incidental Mutation 'IGL02345:Vmn2r41'
ID289229
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn2r41
Ensembl Gene ENSMUSG00000090892
Gene Namevomeronasal 2, receptor 41
Synonyms
Accession Numbers
Is this an essential gene? Not available question?
Stock #IGL02345
Quality Score
Status
Chromosome7
Chromosomal Location8136950-8161654 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to G at 8138768 bp
ZygosityHeterozygous
Amino Acid Change Asparagine to Histidine at position 566 (N566H)
Ref Sequence ENSEMBL: ENSMUSP00000128337 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000168807]
Predicted Effect probably damaging
Transcript: ENSMUST00000168807
AA Change: N566H

PolyPhen 2 Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)
SMART Domains Protein: ENSMUSP00000128337
Gene: ENSMUSG00000090892
AA Change: N566H

DomainStartEndE-ValueType
signal peptide 1 18 N/A INTRINSIC
low complexity region 59 71 N/A INTRINSIC
Pfam:ANF_receptor 73 468 2.6e-32 PFAM
Pfam:NCD3G 512 565 1.5e-19 PFAM
Pfam:7tm_3 595 834 1.5e-78 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 32 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abcc1 G T 16: 14,396,351 D177Y possibly damaging Het
Casc3 T C 11: 98,827,564 probably benign Het
Cnga1 C T 5: 72,605,272 V300I probably benign Het
Dcun1d4 A G 5: 73,511,152 D41G probably damaging Het
Dnm1l T C 16: 16,329,894 S181G possibly damaging Het
Dyrk1a T G 16: 94,671,362 S242A possibly damaging Het
Fcgbp T A 7: 28,071,643 probably benign Het
Fibcd1 T C 2: 31,816,592 Y409C probably damaging Het
Fig4 A T 10: 41,267,774 W230R probably null Het
Flt1 T C 5: 147,582,626 S960G probably benign Het
Fyb A G 15: 6,619,662 S390G possibly damaging Het
Gbx2 T C 1: 89,928,976 T231A probably benign Het
Gm16432 G A 1: 178,015,188 V60I possibly damaging Het
Gm5852 T A 3: 93,727,748 noncoding transcript Het
Lmo7 T C 14: 101,887,473 V456A probably damaging Het
Mark3 A G 12: 111,627,107 N191S probably damaging Het
Olfr871 C A 9: 20,213,018 S223Y possibly damaging Het
Pik3c2a C T 7: 116,405,891 E381K probably damaging Het
Pik3r5 A G 11: 68,492,726 D457G probably benign Het
Plcg2 T C 8: 117,585,180 S404P probably damaging Het
Prr16 T C 18: 51,303,229 F260S probably damaging Het
Psd4 T C 2: 24,401,823 probably null Het
Ptgs1 A G 2: 36,242,971 D327G probably null Het
Rgsl1 C T 1: 153,804,009 probably null Het
Spg20 T A 3: 55,117,726 probably null Het
Sugp1 A G 8: 70,043,084 probably benign Het
Tubgcp3 A T 8: 12,625,056 I713N probably damaging Het
Usp19 A G 9: 108,493,858 T240A probably benign Het
Vash2 A G 1: 190,978,215 V81A probably benign Het
Wdr31 A G 4: 62,458,846 I42T possibly damaging Het
Zfp292 C T 4: 34,809,244 V1272I possibly damaging Het
Zfp638 C T 6: 83,984,875 R1899C probably damaging Het
Other mutations in Vmn2r41
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL03342:Vmn2r41 APN 7 8138683 missense probably damaging 0.99
R5103:Vmn2r41 UTSW 7 8138342 missense probably benign 0.00
R5440:Vmn2r41 UTSW 7 8138363 missense probably damaging 1.00
R6232:Vmn2r41 UTSW 7 8150215 critical splice donor site probably null
R6603:Vmn2r41 UTSW 7 8138360 missense probably damaging 1.00
R7847:Vmn2r41 UTSW 7 8161548 missense probably benign 0.01
R7930:Vmn2r41 UTSW 7 8161548 missense probably benign 0.01
Posted On2015-04-16