Incidental Mutation 'IGL02335:Gm1110'
ID 289703
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm1110
Ensembl Gene ENSMUSG00000079644
Gene Name predicted gene 1110
Synonyms LOC382064
Accession Numbers
Essential gene? Probably non essential (E-score: 0.060) question?
Stock # IGL02335
Quality Score
Status
Chromosome 9
Chromosomal Location 26879567-26923111 bp(-) (GRCm38)
Type of Mutation missense
DNA Base Change (assembly) T to C at 26881763 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change Isoleucine to Methionine at position 572 (I572M)
Ref Sequence ENSEMBL: ENSMUSP00000110916 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000115261]
AlphaFold F6Y113
Predicted Effect probably benign
Transcript: ENSMUST00000115261
AA Change: I572M

PolyPhen 2 Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
SMART Domains Protein: ENSMUSP00000110916
Gene: ENSMUSG00000079644
AA Change: I572M

DomainStartEndE-ValueType
signal peptide 1 24 N/A INTRINSIC
Pfam:Glyco_hydro_35 55 368 2e-93 PFAM
Pfam:Glyco_hydro_42 70 229 1e-12 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000214847
Predicted Effect noncoding transcript
Transcript: ENSMUST00000217197
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 45 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
5830411N06Rik A T 7: 140,296,540 N526Y probably damaging Het
A4gnt C T 9: 99,620,213 T142I probably benign Het
Acaca A G 11: 84,214,258 T147A possibly damaging Het
Agbl3 A G 6: 34,799,750 D397G probably damaging Het
Ank1 C T 8: 23,135,638 T1597M possibly damaging Het
Arl4d A G 11: 101,666,929 T94A possibly damaging Het
Cd22 A G 7: 30,876,134 I161T probably damaging Het
Clcn7 C T 17: 25,146,847 L166F probably benign Het
Cnbd1 G T 4: 19,055,095 N110K possibly damaging Het
Col14a1 A T 15: 55,463,769 probably benign Het
Col6a6 C T 9: 105,784,101 V270M probably damaging Het
Cox8b C A 7: 140,899,077 G42W probably damaging Het
Csn1s1 A T 5: 87,680,845 D275V probably benign Het
Cubn T A 2: 13,427,834 probably null Het
Dctn2 T C 10: 127,275,821 probably benign Het
Dnm1l A G 16: 16,342,740 probably benign Het
Dpp4 T C 2: 62,334,644 E687G probably benign Het
Fbxw20 T C 9: 109,223,309 K249E possibly damaging Het
Fhl2 C T 1: 43,128,390 W181* probably null Het
G2e3 T A 12: 51,369,158 M559K probably benign Het
Gdap1l1 A T 2: 163,447,595 Y160F possibly damaging Het
Gm5538 G A 3: 59,743,605 M49I probably benign Het
Gpatch2l T A 12: 86,256,937 probably benign Het
Kcnq4 A G 4: 120,715,854 L250P probably damaging Het
Lamc2 A T 1: 153,166,216 N57K probably benign Het
Lingo1 A G 9: 56,620,081 L408P probably damaging Het
Mmrn1 A T 6: 60,977,147 N804I possibly damaging Het
Mroh7 A G 4: 106,707,782 L545S probably damaging Het
Nup188 T A 2: 30,323,636 probably null Het
Olfr1442 T C 19: 12,674,238 I11T probably damaging Het
Olfr1494 A G 19: 13,749,934 D276G probably benign Het
Olfr96 A G 17: 37,225,326 N67S probably damaging Het
Pls1 A T 9: 95,784,183 N138K probably benign Het
Prkch C A 12: 73,702,512 N345K probably benign Het
Reps1 T C 10: 18,056,117 probably null Het
Rrp7a T C 15: 83,122,691 E15G probably benign Het
Scn1a T A 2: 66,277,661 T1557S possibly damaging Het
Smtn T C 11: 3,526,215 E602G probably damaging Het
Syvn1 T C 19: 6,050,093 probably null Het
Tbxas1 A G 6: 39,023,080 D267G probably damaging Het
Topbp1 A G 9: 103,328,523 N787D probably damaging Het
Vmn2r22 T G 6: 123,638,092 S180R probably damaging Het
Zfp345 T A 2: 150,474,543 E48D possibly damaging Het
Zfp608 G A 18: 54,897,437 Q1144* probably null Het
Zfp936 T A 7: 43,187,267 L34Q probably damaging Het
Other mutations in Gm1110
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00591:Gm1110 APN 9 26,880,874 (GRCm38) nonsense probably null
IGL01089:Gm1110 APN 9 26,881,860 (GRCm38) missense probably benign
IGL01631:Gm1110 APN 9 26,897,916 (GRCm38) critical splice donor site probably null
IGL02008:Gm1110 APN 9 26,883,230 (GRCm38) missense probably benign 0.09
IGL02331:Gm1110 APN 9 26,913,287 (GRCm38) critical splice donor site probably null
IGL02550:Gm1110 APN 9 26,881,834 (GRCm38) missense probably benign 0.09
IGL02614:Gm1110 APN 9 26,920,714 (GRCm38) missense probably benign 0.11
IGL03409:Gm1110 APN 9 26,896,620 (GRCm38) missense probably benign 0.21
PIT4458001:Gm1110 UTSW 9 26,880,828 (GRCm38) missense probably benign 0.00
R0189:Gm1110 UTSW 9 26,883,218 (GRCm38) missense probably null 0.99
R0271:Gm1110 UTSW 9 26,920,666 (GRCm38) missense probably damaging 1.00
R1034:Gm1110 UTSW 9 26,921,350 (GRCm38) missense probably damaging 1.00
R1229:Gm1110 UTSW 9 26,881,806 (GRCm38) missense probably benign
R1355:Gm1110 UTSW 9 26,883,761 (GRCm38) missense probably benign 0.01
R1566:Gm1110 UTSW 9 26,880,870 (GRCm38) missense probably damaging 1.00
R1574:Gm1110 UTSW 9 26,881,126 (GRCm38) splice site probably benign
R1916:Gm1110 UTSW 9 26,889,638 (GRCm38) missense probably damaging 1.00
R2011:Gm1110 UTSW 9 26,894,258 (GRCm38) missense probably benign 0.01
R2214:Gm1110 UTSW 9 26,902,490 (GRCm38) missense probably benign 0.37
R2567:Gm1110 UTSW 9 26,920,696 (GRCm38) missense probably benign
R2967:Gm1110 UTSW 9 26,881,043 (GRCm38) missense probably benign 0.05
R4271:Gm1110 UTSW 9 26,895,648 (GRCm38) critical splice donor site probably null
R4683:Gm1110 UTSW 9 26,920,594 (GRCm38) missense probably damaging 0.99
R4945:Gm1110 UTSW 9 26,920,595 (GRCm38) missense possibly damaging 0.46
R5015:Gm1110 UTSW 9 26,881,866 (GRCm38) missense probably benign 0.01
R5089:Gm1110 UTSW 9 26,882,387 (GRCm38) missense probably damaging 0.96
R5225:Gm1110 UTSW 9 26,902,478 (GRCm38) missense probably damaging 1.00
R5239:Gm1110 UTSW 9 26,893,570 (GRCm38) missense probably benign 0.00
R5395:Gm1110 UTSW 9 26,889,632 (GRCm38) missense probably benign
R5783:Gm1110 UTSW 9 26,882,336 (GRCm38) missense probably benign
R6045:Gm1110 UTSW 9 26,883,209 (GRCm38) critical splice donor site probably null
R6245:Gm1110 UTSW 9 26,920,747 (GRCm38) missense probably benign 0.04
R6357:Gm1110 UTSW 9 26,914,128 (GRCm38) splice site probably null
R6863:Gm1110 UTSW 9 26,881,064 (GRCm38) missense probably damaging 1.00
R7336:Gm1110 UTSW 9 26,914,357 (GRCm38) missense probably damaging 0.99
R7454:Gm1110 UTSW 9 26,920,649 (GRCm38) missense probably benign
R7555:Gm1110 UTSW 9 26,893,628 (GRCm38) missense probably benign 0.05
R7579:Gm1110 UTSW 9 26,883,826 (GRCm38) missense possibly damaging 0.93
R7990:Gm1110 UTSW 9 26,880,841 (GRCm38) missense possibly damaging 0.66
R8062:Gm1110 UTSW 9 26,881,821 (GRCm38) missense probably damaging 0.99
R8108:Gm1110 UTSW 9 26,920,661 (GRCm38) missense probably damaging 1.00
R8323:Gm1110 UTSW 9 26,902,423 (GRCm38) critical splice donor site probably null
R8354:Gm1110 UTSW 9 26,883,281 (GRCm38) missense probably benign 0.00
R8354:Gm1110 UTSW 9 26,883,280 (GRCm38) missense probably benign 0.01
R8454:Gm1110 UTSW 9 26,883,281 (GRCm38) missense probably benign 0.00
R8454:Gm1110 UTSW 9 26,883,280 (GRCm38) missense probably benign 0.01
R8494:Gm1110 UTSW 9 26,880,858 (GRCm38) missense probably benign 0.04
R8978:Gm1110 UTSW 9 26,895,799 (GRCm38) splice site probably benign
R9321:Gm1110 UTSW 9 26,920,595 (GRCm38) missense probably benign 0.00
R9513:Gm1110 UTSW 9 26,883,787 (GRCm38) missense possibly damaging 0.95
R9545:Gm1110 UTSW 9 26,889,681 (GRCm38) missense probably benign 0.00
R9758:Gm1110 UTSW 9 26,889,598 (GRCm38) nonsense probably null
RF002:Gm1110 UTSW 9 26,920,640 (GRCm38) missense probably damaging 1.00
X0063:Gm1110 UTSW 9 26,894,280 (GRCm38) missense probably benign 0.01
Z1088:Gm1110 UTSW 9 26,913,310 (GRCm38) missense probably benign 0.01
Posted On 2015-04-16