Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02285:Gpi-ps'

289970

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gpi-ps

Ensembl Gene

ENSMUSG00000043192

Gene Name

glucose-6-phosphate isomerase, pseudogene

Synonyms

LOC233995, Gm1840

Accession Numbers

Essential gene?

Probably essential (E-score: 0.919) question?

Stock #

IGL02285

Quality Score

Status

Chromosome

Chromosomal Location

5689580-5691011 bp(+) (GRCm39)

Type of Mutation

exon

DNA Base Change (assembly)

C to T at 5690373 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000051687

SMART Domains

Protein: ENSMUSP00000127885
Gene: ENSMUSG00000043192

Domain	Start	End	E-Value	Type
Pfam:PGI	48	130	1.2e-34	PFAM
Pfam:PGI	127	463	1.2e-181	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 38 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Ago3	A	G	4: 126,244,670 (GRCm39)	V672A	possibly damaging	Het
Arhgef28	A	T	13: 98,187,536 (GRCm39)	V253D	possibly damaging	Het
Atg3	G	A	16: 44,998,680 (GRCm39)		probably benign	Het
Camsap1	T	C	2: 25,819,814 (GRCm39)	D1557G	probably damaging	Het
Cdh20	A	G	1: 110,065,921 (GRCm39)	T732A	probably damaging	Het
Cert1	A	G	13: 96,752,990 (GRCm39)	H348R	probably benign	Het
Cyp3a13	T	A	5: 137,908,229 (GRCm39)	I207F	probably benign	Het
Dock1	T	G	7: 134,683,649 (GRCm39)		probably null	Het
Drc7	A	T	8: 95,797,861 (GRCm39)		probably benign	Het
Drosha	C	A	15: 12,833,950 (GRCm39)	P18H	unknown	Het
Fbxl5	A	G	5: 43,922,690 (GRCm39)	S243P	possibly damaging	Het
Filip1	A	G	9: 79,727,408 (GRCm39)	C404R	probably damaging	Het
Gm5745	G	A	9: 73,082,780 (GRCm39)		noncoding transcript	Het
Gm7808	T	G	9: 19,839,347 (GRCm39)		probably benign	Het
Hcn3	T	C	3: 89,060,119 (GRCm39)	D175G	probably damaging	Het
Igkv1-117	A	T	6: 68,098,519 (GRCm39)	M23L	probably benign	Het
Kif26a	A	G	12: 112,123,941 (GRCm39)	D182G	probably damaging	Het
Lmbr1	A	G	5: 29,459,233 (GRCm39)		probably benign	Het
Lypd4	T	A	7: 24,564,865 (GRCm39)	Q91L	probably damaging	Het
Ncoa5	C	T	2: 164,844,760 (GRCm39)	A37T	probably damaging	Het
Or52ad1	G	A	7: 102,995,245 (GRCm39)	R297*	probably null	Het
Or56b1	A	G	7: 104,284,932 (GRCm39)	E17G	probably benign	Het
Or7g17	T	A	9: 18,768,286 (GRCm39)	C122S	possibly damaging	Het
Ppp1r18	A	G	17: 36,178,148 (GRCm39)	K8E	probably damaging	Het
Ppp3ca	A	G	3: 136,634,387 (GRCm39)		probably benign	Het
Ptpn12	T	A	5: 21,260,711 (GRCm39)	Q12L	probably benign	Het
Rpgrip1l	A	G	8: 91,959,535 (GRCm39)	F1122L	possibly damaging	Het
Rps15	G	T	10: 80,129,596 (GRCm39)	M43I	probably benign	Het
Rrp15	T	C	1: 186,453,592 (GRCm39)		probably benign	Het
Sash1	A	T	10: 8,616,098 (GRCm39)	M588K	probably damaging	Het
Slc12a7	A	G	13: 73,943,714 (GRCm39)		probably benign	Het
Slc25a13	A	G	6: 6,042,643 (GRCm39)	V587A	possibly damaging	Het
Sugct	T	C	13: 17,847,181 (GRCm39)	D34G	possibly damaging	Het
Tdpoz2	T	A	3: 93,559,598 (GRCm39)	I125F	probably damaging	Het
Trim52	T	A	14: 106,344,702 (GRCm39)	L120Q	probably damaging	Het
Vmn1r85	T	C	7: 12,818,711 (GRCm39)	I144M	probably damaging	Het
Vmn2r107	T	C	17: 20,595,823 (GRCm39)	F792S	probably damaging	Het
Vsnl1	A	G	12: 11,436,878 (GRCm39)	F34L	probably damaging	Het

Other mutations in Gpi-ps

Allele	Source	Chr	Coord	Type	Predicted Effect
IGL00497:Gpi-ps	APN	8	5,690,563 (GRCm39)	exon	noncoding transcript
IGL01556:Gpi-ps	APN	8	5,689,833 (GRCm39)	exon	noncoding transcript
IGL01721:Gpi-ps	APN	8	5,689,896 (GRCm39)	exon	noncoding transcript
IGL02008:Gpi-ps	APN	8	5,689,896 (GRCm39)	exon	noncoding transcript
IGL02200:Gpi-ps	APN	8	5,689,968 (GRCm39)	exon	noncoding transcript
IGL02354:Gpi-ps	APN	8	5,690,896 (GRCm39)	exon	noncoding transcript
IGL02361:Gpi-ps	APN	8	5,690,896 (GRCm39)	exon	noncoding transcript
IGL03052:Gpi-ps	APN	8	5,689,816 (GRCm39)	exon	noncoding transcript
R0114:Gpi-ps	UTSW	8	5,690,359 (GRCm39)	exon	noncoding transcript
R0480:Gpi-ps	UTSW	8	5,689,888 (GRCm39)	exon	noncoding transcript
R4760:Gpi-ps	UTSW	8	5,690,473 (GRCm39)	exon	noncoding transcript
R5076:Gpi-ps	UTSW	8	5,690,130 (GRCm39)	exon	noncoding transcript

Posted On

2015-04-16