Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02293:Fpr-rs7'

290099

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Fpr-rs7

Ensembl Gene

ENSMUSG00000071276

Gene Name

formyl peptide receptor, related sequence 7

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.110) question?

Stock #

IGL02293

Quality Score

Status

Chromosome

Chromosomal Location

20113210-20114226 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 20113970 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Valine to Alanine at position 86 (V86A)

Ref Sequence

ENSEMBL: ENSMUSP00000093297 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000095637]

AlphaFold

Q71MR7

Predicted Effect

probably benign
Transcript: ENSMUST00000095637
AA Change: V86A

PolyPhen 2 Score 0.010 (Sensitivity: 0.96; Specificity: 0.77)

SMART Domains

Protein: ENSMUSP00000093297
Gene: ENSMUSG00000071276
AA Change: V86A

Domain	Start	End	E-Value	Type
Pfam:7tm_1	43	297	1.2e-38	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000176711

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 31 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2610507B11Rik	T	A	11: 78,271,910	L866H	probably damaging	Het
Agtr1a	A	G	13: 30,381,357	K135R	probably benign	Het
Ahdc1	C	T	4: 133,065,618	A1390V	possibly damaging	Het
Aldh1a2	A	G	9: 71,285,277		probably null	Het
C6	T	A	15: 4,755,303	I217K	probably benign	Het
Ccr1l1	G	A	9: 123,977,936	T158I	possibly damaging	Het
Dnah6	A	T	6: 73,133,650		probably benign	Het
Ect2l	A	G	10: 18,140,511		probably null	Het
Endov	T	C	11: 119,505,173		probably benign	Het
Gle1	A	G	2: 29,957,760	I660V	probably benign	Het
Gm2056	A	G	12: 88,027,263	N87S	probably benign	Het
Hk2	A	T	6: 82,743,975	D159E	probably benign	Het
Hmcn1	A	G	1: 150,664,915	V2881A	probably damaging	Het
Hspa14	T	C	2: 3,511,034	K68E	probably damaging	Het
Ifi207	A	T	1: 173,723,748	I974N	probably damaging	Het
Igkv4-71	A	C	6: 69,243,322	S42A	possibly damaging	Het
Itgb4	G	A	11: 115,988,926	V635I	probably damaging	Het
Klhl32	A	G	4: 24,626,935	Y555H	probably damaging	Het
Lmbrd2	T	C	15: 9,172,189	S357P	probably benign	Het
Mfsd1	T	A	3: 67,598,092	V380D	probably damaging	Het
Ndc80	A	G	17: 71,514,278	F225S	probably damaging	Het
Olfr134	G	T	17: 38,175,686	V201L	probably benign	Het
Olfr320	T	C	11: 58,684,170	V99A	probably benign	Het
Plxnd1	A	G	6: 115,963,913	V1355A	probably damaging	Het
Prkd1	A	G	12: 50,489,978	S108P	probably damaging	Het
Ptges3	C	T	10: 128,075,335		probably benign	Het
Rabggta	G	T	14: 55,721,696	L5M	probably benign	Het
Rag1	C	T	2: 101,643,046	D584N	probably benign	Het
Rasl12	A	G	9: 65,408,311	D79G	probably benign	Het
Rhoj	A	G	12: 75,375,412		probably benign	Het
Slc4a9	T	C	18: 36,533,215	L483P	probably benign	Het

Other mutations in Fpr-rs7

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00332:Fpr-rs7	APN	17	20113218	nonsense	probably null
IGL01386:Fpr-rs7	APN	17	20114192	missense	probably damaging	0.98
IGL03303:Fpr-rs7	APN	17	20113739	missense	possibly damaging	0.55
R0731:Fpr-rs7	UTSW	17	20113854	missense	probably benign	0.00
R0826:Fpr-rs7	UTSW	17	20113626	missense	probably benign	0.01
R1439:Fpr-rs7	UTSW	17	20113607	missense	probably benign	0.10
R1590:Fpr-rs7	UTSW	17	20113416	missense	probably benign	0.05
R1778:Fpr-rs7	UTSW	17	20114015	missense	probably damaging	1.00
R4715:Fpr-rs7	UTSW	17	20113428	missense	probably benign	0.00
R4744:Fpr-rs7	UTSW	17	20114003	missense	probably benign	0.17
R4921:Fpr-rs7	UTSW	17	20113820	missense	possibly damaging	0.70
R5540:Fpr-rs7	UTSW	17	20114094	missense	probably damaging	1.00
R5677:Fpr-rs7	UTSW	17	20114103	missense	probably benign
R5959:Fpr-rs7	UTSW	17	20113749	missense	probably benign	0.01
R6042:Fpr-rs7	UTSW	17	20113215	missense	probably benign	0.00
R7921:Fpr-rs7	UTSW	17	20113405	missense	probably benign	0.03
R7984:Fpr-rs7	UTSW	17	20113409	missense	probably benign	0.01
R8137:Fpr-rs7	UTSW	17	20113793	missense	possibly damaging	0.49
R8172:Fpr-rs7	UTSW	17	20114181	missense	probably benign	0.04
R8762:Fpr-rs7	UTSW	17	20113527	missense	probably benign	0.07
R9134:Fpr-rs7	UTSW	17	20114063	missense	probably damaging	1.00
Z1176:Fpr-rs7	UTSW	17	20113393	missense	probably benign	0.02

Posted On

2015-04-16