Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL02291:Vmn1r234'

290324

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r234

Ensembl Gene

ENSMUSG00000057203

Gene Name

vomeronasal 1 receptor 234

Synonyms

V1rf1

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.056) question?

Stock #

IGL02291

Quality Score

Status

Chromosome

Chromosomal Location

21228826-21229815 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

G to A at 21228931 bp

Zygosity

Heterozygous

Amino Acid Change

Valine to Isoleucine at position 36 (V36I)

Ref Sequence

ENSEMBL: ENSMUSP00000078579 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000079633]

Predicted Effect

probably benign
Transcript: ENSMUST00000079633
AA Change: V36I

PolyPhen 2 Score 0.280 (Sensitivity: 0.91; Specificity: 0.88)

SMART Domains

Protein: ENSMUSP00000078579
Gene: ENSMUSG00000057203
AA Change: V36I

Domain	Start	End	E-Value	Type
Pfam:TAS2R	25	315	2.8e-14	PFAM
Pfam:V1R	57	318	2.3e-26	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000177028

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 29 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
AF366264	T	A	8: 13,837,704	N129I	probably benign	Het
Arhgap10	T	A	8: 77,382,715		probably benign	Het
Cfap161	C	T	7: 83,791,639	G135D	probably benign	Het
Cpne1	A	G	2: 156,078,420	V179A	probably damaging	Het
Cpsf1	A	T	15: 76,602,821	I219N	probably damaging	Het
Creb3l4	T	G	3: 90,241,983	R139S	probably benign	Het
Fer1l4	T	C	2: 156,019,538	K1929E	probably damaging	Het
Gm5431	A	G	11: 48,888,964	L655P	probably damaging	Het
Igsf3	T	G	3: 101,439,529	H613Q	probably damaging	Het
Kcnab1	T	C	3: 65,357,082	Y251H	possibly damaging	Het
Kmt2d	T	C	15: 98,865,492		probably benign	Het
Krt17	A	T	11: 100,256,493	V404E	probably benign	Het
Lipo2	A	G	19: 33,745,792	I199T	possibly damaging	Het
Mks1	T	A	11: 87,859,667		probably benign	Het
Nlrp1a	A	T	11: 71,122,589		probably null	Het
Nup210	T	C	6: 91,101,268	D100G	probably damaging	Het
Olfr108	G	A	17: 37,446,285	V255I	possibly damaging	Het
Olfr1393	T	A	11: 49,280,985	I279N	probably damaging	Het
Olfr532	A	T	7: 140,419,287	L162Q	probably damaging	Het
Olfr871	T	C	9: 20,212,802	I151T	probably benign	Het
Psmd5	A	G	2: 34,857,799	V282A	probably benign	Het
Rasal3	A	T	17: 32,393,737		probably benign	Het
Rnf10	T	C	5: 115,260,196	N93D	probably damaging	Het
Slc7a9	G	A	7: 35,457,014	G294R	probably damaging	Het
Taf7	C	T	18: 37,643,362	G51R	possibly damaging	Het
Tas2r126	G	A	6: 42,435,287	M251I	probably benign	Het
Trim33	T	C	3: 103,326,865	F473S	probably damaging	Het
Vmn1r127	A	G	7: 21,319,074	L263P	possibly damaging	Het
Vmn2r84	T	A	10: 130,390,748	H407L	probably damaging	Het

Other mutations in Vmn1r234

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00089:Vmn1r234	APN	17	21229598	missense	possibly damaging	0.95
IGL01485:Vmn1r234	APN	17	21228909	missense	possibly damaging	0.53
IGL02149:Vmn1r234	APN	17	21229007	missense	probably benign	0.00
IGL02993:Vmn1r234	APN	17	21229703	missense	probably damaging	0.99
IGL03223:Vmn1r234	APN	17	21229391	missense	probably damaging	0.98
R0626:Vmn1r234	UTSW	17	21229745	missense	probably benign	0.17
R1274:Vmn1r234	UTSW	17	21229251	frame shift	probably null
R1275:Vmn1r234	UTSW	17	21229251	frame shift	probably null
R1288:Vmn1r234	UTSW	17	21229251	frame shift	probably null
R1289:Vmn1r234	UTSW	17	21229251	frame shift	probably null
R1319:Vmn1r234	UTSW	17	21228910	missense	probably benign	0.01
R1412:Vmn1r234	UTSW	17	21229250	missense	probably benign	0.01
R2323:Vmn1r234	UTSW	17	21229703	missense	probably benign	0.10
R3755:Vmn1r234	UTSW	17	21229009	missense	probably damaging	0.98
R4299:Vmn1r234	UTSW	17	21229021	missense	probably benign	0.03
R5301:Vmn1r234	UTSW	17	21229327	missense	probably benign	0.11
R5741:Vmn1r234	UTSW	17	21229469	missense	probably benign	0.21
R6197:Vmn1r234	UTSW	17	21229327	missense	probably benign	0.04
R6218:Vmn1r234	UTSW	17	21229721	missense	possibly damaging	0.71
R6486:Vmn1r234	UTSW	17	21229342	missense	probably benign	0.11
R7482:Vmn1r234	UTSW	17	21229375	missense	probably benign	0.07
R7635:Vmn1r234	UTSW	17	21229217	missense	probably damaging	1.00
R8295:Vmn1r234	UTSW	17	21228839	missense	probably benign	0.01
X0028:Vmn1r234	UTSW	17	21228890	missense	probably benign	0.17

Posted On

2015-04-16