Incidental Mutation 'IGL02370:Trerf1'
ID 290885
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Trerf1
Ensembl Gene ENSMUSG00000064043
Gene Name transcriptional regulating factor 1
Synonyms Trep132, 9430096I18Rik, Trep-132
Accession Numbers
Essential gene? Possibly non essential (E-score: 0.472) question?
Stock # IGL02370
Quality Score
Chromosome 17
Chromosomal Location 47140875-47361958 bp(+) (GRCm38)
Type of Mutation exon
DNA Base Change (assembly) C to T at 47314461 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s):
AlphaFold no structure available at present
Predicted Effect noncoding transcript
Transcript: ENSMUST00000077951
SMART Domains Protein: ENSMUSP00000077103
Gene: ENSMUSG00000064043

low complexity region 262 279 N/A INTRINSIC
low complexity region 291 342 N/A INTRINSIC
low complexity region 373 384 N/A INTRINSIC
ZnF_C2H2 512 534 1.2e-3 SMART
low complexity region 552 580 N/A INTRINSIC
low complexity region 666 679 N/A INTRINSIC
low complexity region 690 704 N/A INTRINSIC
low complexity region 732 742 N/A INTRINSIC
low complexity region 764 779 N/A INTRINSIC
ELM2 807 863 7.65e-13 SMART
SANT 912 960 2.18e-5 SMART
coiled coil region 981 1005 N/A INTRINSIC
ZnF_C2H2 1039 1063 2.75e-3 SMART
low complexity region 1092 1106 N/A INTRINSIC
ZnF_C2H2 1112 1134 1.1e-2 SMART
low complexity region 1135 1156 N/A INTRINSIC
low complexity region 1182 1200 N/A INTRINSIC
low complexity region 1208 1222 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000188730
Predicted Effect noncoding transcript
Transcript: ENSMUST00000188947
Predicted Effect noncoding transcript
Transcript: ENSMUST00000190020
Predicted Effect noncoding transcript
Transcript: ENSMUST00000190080
Predicted Effect noncoding transcript
Transcript: ENSMUST00000191153
Coding Region Coverage
Validation Efficiency
MGI Phenotype FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a zinc-finger transcriptional regulating protein which interacts with CBP/p300 to regulate the human gene CYP11A1. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
Allele List at MGI
Other mutations in this stock
Total: 46 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1300017J02Rik A G 9: 103,263,074 (GRCm38) V482A probably benign Het
4732471J01Rik T C 7: 25,384,888 (GRCm38) probably benign Het
Abra T C 15: 41,869,244 (GRCm38) D142G probably damaging Het
Aldh9a1 A G 1: 167,356,532 (GRCm38) N199D probably damaging Het
Baz2b A T 2: 59,923,589 (GRCm38) I1130N possibly damaging Het
Cacna1s A G 1: 136,085,347 (GRCm38) I312V probably damaging Het
Chrd A G 16: 20,735,791 (GRCm38) M367V possibly damaging Het
Clec12a C T 6: 129,354,576 (GRCm38) A160V possibly damaging Het
Cnnm1 T C 19: 43,471,950 (GRCm38) probably null Het
Cntnap3 A T 13: 64,751,751 (GRCm38) M976K probably benign Het
Cyp27b1 T C 10: 127,050,674 (GRCm38) probably benign Het
Ddx54 T A 5: 120,619,787 (GRCm38) L226Q probably damaging Het
Dnah7a A G 1: 53,635,397 (GRCm38) V407A probably benign Het
Elp4 A G 2: 105,794,592 (GRCm38) S201P probably damaging Het
Exoc3 A T 13: 74,192,761 (GRCm38) V308D probably benign Het
Exosc3 A G 4: 45,319,671 (GRCm38) I117T probably damaging Het
Gbx2 A T 1: 89,929,149 (GRCm38) probably benign Het
Gm4858 A G 3: 93,074,047 (GRCm38) D124G possibly damaging Het
Hnf1b A C 11: 83,882,733 (GRCm38) T253P possibly damaging Het
Itih5 A T 2: 10,186,975 (GRCm38) Y107F probably benign Het
Kcnb2 A G 1: 15,710,935 (GRCm38) N677S probably benign Het
Knstrn T A 2: 118,823,788 (GRCm38) probably null Het
Lin9 G T 1: 180,688,018 (GRCm38) C451F probably damaging Het
Mast1 A C 8: 84,912,254 (GRCm38) V1482G probably benign Het
Mroh4 A G 15: 74,625,541 (GRCm38) F144L probably benign Het
Myrf T C 19: 10,214,140 (GRCm38) N945D probably benign Het
Nfrkb G A 9: 31,389,012 (GRCm38) G33D probably benign Het
Olfr1036 C A 2: 86,074,788 (GRCm38) T16K probably damaging Het
P2ry13 T C 3: 59,209,465 (GRCm38) I297M probably damaging Het
Pcdhb21 T A 18: 37,514,592 (GRCm38) probably null Het
Pitpnm3 A G 11: 72,051,858 (GRCm38) Y868H probably benign Het
Pou2f3 G A 9: 43,137,348 (GRCm38) R266W probably damaging Het
Rcn3 T C 7: 45,083,333 (GRCm38) S304G probably benign Het
Rinl A G 7: 28,794,972 (GRCm38) probably null Het
Sema5a T C 15: 32,682,299 (GRCm38) probably benign Het
Sipa1l2 A G 8: 125,480,269 (GRCm38) L565P probably damaging Het
Slc5a9 A G 4: 111,877,629 (GRCm38) I656T probably benign Het
Sptan1 A G 2: 30,030,740 (GRCm38) K2404R probably damaging Het
Tarsl2 C A 7: 65,661,165 (GRCm38) P314Q probably benign Het
Tbc1d14 C T 5: 36,495,218 (GRCm38) V627I possibly damaging Het
Tfcp2 A T 15: 100,512,304 (GRCm38) V394D probably damaging Het
Ucp2 A G 7: 100,498,384 (GRCm38) N190S probably damaging Het
Vmn2r124 A G 17: 18,064,191 (GRCm38) Q498R probably benign Het
Yeats2 T A 16: 20,150,471 (GRCm38) I4N probably damaging Het
Zfp574 T G 7: 25,079,589 (GRCm38) I12S possibly damaging Het
Zscan29 T A 2: 121,163,833 (GRCm38) E522V probably benign Het
Other mutations in Trerf1
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01610:Trerf1 APN 17 47,319,575 (GRCm38) unclassified noncoding transcript
IGL01753:Trerf1 APN 17 47,315,436 (GRCm38) exon noncoding transcript
IGL02172:Trerf1 APN 17 47,317,817 (GRCm38) exon noncoding transcript
IGL02266:Trerf1 APN 17 47,315,405 (GRCm38) exon noncoding transcript
IGL02613:Trerf1 APN 17 47,348,840 (GRCm38) exon noncoding transcript
R0179:Trerf1 UTSW 17 47,316,662 (GRCm38) critical splice donor site noncoding transcript
R0284:Trerf1 UTSW 17 47,319,545 (GRCm38) unclassified noncoding transcript
R0359:Trerf1 UTSW 17 47,341,136 (GRCm38) exon noncoding transcript
R0689:Trerf1 UTSW 17 47,319,374 (GRCm38) unclassified noncoding transcript
R1460:Trerf1 UTSW 17 47,317,845 (GRCm38) exon noncoding transcript
R1727:Trerf1 UTSW 17 47,341,166 (GRCm38) exon noncoding transcript
R4222:Trerf1 UTSW 17 47,314,801 (GRCm38) exon noncoding transcript
R4562:Trerf1 UTSW 17 47,327,071 (GRCm38) exon noncoding transcript
R4770:Trerf1 UTSW 17 47,319,655 (GRCm38) unclassified noncoding transcript
R5366:Trerf1 UTSW 17 47,315,190 (GRCm38) exon noncoding transcript
R5919:Trerf1 UTSW 17 47,323,282 (GRCm38) unclassified noncoding transcript
R5963:Trerf1 UTSW 17 47,314,337 (GRCm38) exon noncoding transcript
R5975:Trerf1 UTSW 17 47,314,271 (GRCm38) exon noncoding transcript
Posted On 2015-04-16