Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02370:Rinl'

290913

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Rinl

Ensembl Gene

ENSMUSG00000051735

Gene Name

Ras and Rab interactor-like

Synonyms

9930116N10Rik, 5830482F20Rik

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL02370

Quality Score

Status

Chromosome

Chromosomal Location

28488394-28498388 bp(+) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

A to G at 28494397 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000146576 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000059857] [ENSMUST00000209035]

AlphaFold

Q80UW3

Predicted Effect

probably null
Transcript: ENSMUST00000059857

SMART Domains

Protein: ENSMUSP00000058447
Gene: ENSMUSG00000051735

Domain	Start	End	E-Value	Type
Blast:SH2	50	132	2e-38	BLAST
SCOP:d1lkka_	69	143	3e-3	SMART
low complexity region	183	196	N/A	INTRINSIC
low complexity region	376	395	N/A	INTRINSIC
Pfam:VPS9	410	514	2.5e-21	PFAM
low complexity region	542	553	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000207345

Predicted Effect

probably null
Transcript: ENSMUST00000207462

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000208149

Predicted Effect

probably null
Transcript: ENSMUST00000209035

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 46 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4732471J01Rik	T	C	7: 25,084,313 (GRCm39)		probably benign	Het
Abra	T	C	15: 41,732,640 (GRCm39)	D142G	probably damaging	Het
Aldh9a1	A	G	1: 167,184,101 (GRCm39)	N199D	probably damaging	Het
Baz2b	A	T	2: 59,753,933 (GRCm39)	I1130N	possibly damaging	Het
Cacna1s	A	G	1: 136,013,085 (GRCm39)	I312V	probably damaging	Het
Chrd	A	G	16: 20,554,541 (GRCm39)	M367V	possibly damaging	Het
Clec12a	C	T	6: 129,331,539 (GRCm39)	A160V	possibly damaging	Het
Cnnm1	T	C	19: 43,460,389 (GRCm39)		probably null	Het
Cntnap3	A	T	13: 64,899,565 (GRCm39)	M976K	probably benign	Het
Cyp27b1	T	C	10: 126,886,543 (GRCm39)		probably benign	Het
Ddx54	T	A	5: 120,757,852 (GRCm39)	L226Q	probably damaging	Het
Dnah7a	A	G	1: 53,674,556 (GRCm39)	V407A	probably benign	Het
Elp4	A	G	2: 105,624,937 (GRCm39)	S201P	probably damaging	Het
Exoc3	A	T	13: 74,340,880 (GRCm39)	V308D	probably benign	Het
Exosc3	A	G	4: 45,319,671 (GRCm39)	I117T	probably damaging	Het
Gbx2	A	T	1: 89,856,871 (GRCm39)		probably benign	Het
Hnf1b	A	C	11: 83,773,559 (GRCm39)	T253P	possibly damaging	Het
Inhca	A	G	9: 103,140,273 (GRCm39)	V482A	probably benign	Het
Itih5	A	T	2: 10,191,786 (GRCm39)	Y107F	probably benign	Het
Kcnb2	A	G	1: 15,781,159 (GRCm39)	N677S	probably benign	Het
Knstrn	T	A	2: 118,654,269 (GRCm39)		probably null	Het
Lin9	G	T	1: 180,515,583 (GRCm39)	C451F	probably damaging	Het
Mast1	A	C	8: 85,638,883 (GRCm39)	V1482G	probably benign	Het
Mroh4	A	G	15: 74,497,390 (GRCm39)	F144L	probably benign	Het
Myrf	T	C	19: 10,191,504 (GRCm39)	N945D	probably benign	Het
Nfrkb	G	A	9: 31,300,308 (GRCm39)	G33D	probably benign	Het
Or5m9b	C	A	2: 85,905,132 (GRCm39)	T16K	probably damaging	Het
P2ry13	T	C	3: 59,116,886 (GRCm39)	I297M	probably damaging	Het
Pcdhb21	T	A	18: 37,647,645 (GRCm39)		probably null	Het
Pitpnm3	A	G	11: 71,942,684 (GRCm39)	Y868H	probably benign	Het
Pou2f3	G	A	9: 43,048,643 (GRCm39)	R266W	probably damaging	Het
Rcn3	T	C	7: 44,732,757 (GRCm39)	S304G	probably benign	Het
Sema5a	T	C	15: 32,682,445 (GRCm39)		probably benign	Het
Sipa1l2	A	G	8: 126,207,008 (GRCm39)	L565P	probably damaging	Het
Slc5a9	A	G	4: 111,734,826 (GRCm39)	I656T	probably benign	Het
Sptan1	A	G	2: 29,920,752 (GRCm39)	K2404R	probably damaging	Het
Tars3	C	A	7: 65,310,913 (GRCm39)	P314Q	probably benign	Het
Tbc1d14	C	T	5: 36,652,562 (GRCm39)	V627I	possibly damaging	Het
Tdpoz8	A	G	3: 92,981,354 (GRCm39)	D124G	possibly damaging	Het
Tfcp2	A	T	15: 100,410,185 (GRCm39)	V394D	probably damaging	Het
Trerf1	C	T	17: 47,625,387 (GRCm39)		noncoding transcript	Het
Ucp2	A	G	7: 100,147,591 (GRCm39)	N190S	probably damaging	Het
Vmn2r124	A	G	17: 18,284,453 (GRCm39)	Q498R	probably benign	Het
Yeats2	T	A	16: 19,969,221 (GRCm39)	I4N	probably damaging	Het
Zfp574	T	G	7: 24,779,014 (GRCm39)	I12S	possibly damaging	Het
Zscan29	T	A	2: 120,994,314 (GRCm39)	E522V	probably benign	Het

Other mutations in Rinl

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL03126:Rinl	APN	7	28,495,075 (GRCm39)	splice site	probably benign
IGL03345:Rinl	APN	7	28,496,222 (GRCm39)	missense	possibly damaging	0.55
R1453:Rinl	UTSW	7	28,496,329 (GRCm39)	missense	probably damaging	1.00
R1648:Rinl	UTSW	7	28,497,057 (GRCm39)	missense	probably damaging	1.00
R1722:Rinl	UTSW	7	28,491,669 (GRCm39)	missense	probably damaging	1.00
R2127:Rinl	UTSW	7	28,496,168 (GRCm39)	missense	probably damaging	1.00
R2290:Rinl	UTSW	7	28,491,696 (GRCm39)	missense	probably benign	0.00
R2472:Rinl	UTSW	7	28,489,803 (GRCm39)	missense	possibly damaging	0.83
R2883:Rinl	UTSW	7	28,497,083 (GRCm39)	frame shift	probably null
R4062:Rinl	UTSW	7	28,490,140 (GRCm39)	missense	probably benign
R6180:Rinl	UTSW	7	28,496,365 (GRCm39)	missense	probably benign	0.02
R7080:Rinl	UTSW	7	28,496,101 (GRCm39)	missense	probably damaging	0.99
R8112:Rinl	UTSW	7	28,490,014 (GRCm39)	critical splice acceptor site	probably null
R8893:Rinl	UTSW	7	28,491,747 (GRCm39)	missense	probably damaging	1.00
R9145:Rinl	UTSW	7	28,495,089 (GRCm39)	missense
R9168:Rinl	UTSW	7	28,490,084 (GRCm39)	missense	possibly damaging	0.82
RF044:Rinl	UTSW	7	28,496,988 (GRCm39)	missense	probably damaging	1.00
X0023:Rinl	UTSW	7	28,489,830 (GRCm39)	missense	probably benign
X0066:Rinl	UTSW	7	28,491,768 (GRCm39)	splice site	probably null

Posted On

2015-04-16