Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02379:Antxrl'

291314

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Antxrl

Ensembl Gene

ENSMUSG00000047441

Gene Name

anthrax toxin receptor-like

Synonyms

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL02379

Quality Score

Status

Chromosome

Chromosomal Location

34052707-34076405 bp(+) (GRCm38)

Type of Mutation

splice site

DNA Base Change (assembly)

C to A at 34056535 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000153795 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000058725] [ENSMUST00000178958] [ENSMUST00000226211] [ENSMUST00000227979]

AlphaFold

Q8BVM2

Predicted Effect

probably null
Transcript: ENSMUST00000058725

SMART Domains

Protein: ENSMUSP00000052816
Gene: ENSMUSG00000047441

Domain	Start	End	E-Value	Type
signal peptide	1	27	N/A	INTRINSIC
VWA	74	248	2.9e-19	SMART
Pfam:Anth_Ig	249	351	6.7e-41	PFAM
low complexity region	370	381	N/A	INTRINSIC
low complexity region	392	461	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000178958

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000215823

Predicted Effect

probably null
Transcript: ENSMUST00000226211

Predicted Effect

probably benign
Transcript: ENSMUST00000227979

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 58 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acad10	T	A	5: 121,622,043	I996F	probably damaging	Het
Adamts9	T	A	6: 92,797,033	D1133V	probably damaging	Het
Adi1	T	A	12: 28,679,467	D106E	probably damaging	Het
Agl	A	G	3: 116,779,091	F837S	probably damaging	Het
Alb	T	A	5: 90,465,879	D207E	probably benign	Het
Alms1	T	G	6: 85,629,633	V2286G	probably damaging	Het
Alpl	G	A	4: 137,742,558	A485V	probably damaging	Het
Apc	C	T	18: 34,298,745	T417I	probably benign	Het
Ash2l	T	C	8: 25,822,771	D390G	probably damaging	Het
Asph	G	A	4: 9,474,980	P582S	probably damaging	Het
Bcr	T	A	10: 75,157,148	L825Q	probably benign	Het
Bhlha15	T	A	5: 144,191,341	N90K	probably damaging	Het
Cgnl1	T	A	9: 71,645,553	Y1043F	possibly damaging	Het
Chek1	T	C	9: 36,723,946	D47G	probably benign	Het
Clca4b	T	A	3: 144,921,858	M451L	probably benign	Het
Csnk1g3	T	C	18: 53,933,492	S346P	probably benign	Het
Cspg4	G	T	9: 56,892,609		probably benign	Het
Ctr9	A	G	7: 111,051,519	K884E	probably damaging	Het
Cyld	T	A	8: 88,744,928	C813*	probably null	Het
Fn3k	A	T	11: 121,435,124	T46S	probably benign	Het
Foxred1	T	C	9: 35,209,986	R89G	probably benign	Het
Gpr174	T	C	X: 107,293,478	F299L	probably damaging	Het
Hdac7	T	C	15: 97,808,385	D312G	probably damaging	Het
Il1f8	A	G	2: 24,154,638	S17G	probably benign	Het
Kcna5	G	T	6: 126,534,509	P219T	probably damaging	Het
Kcnh2	A	C	5: 24,326,638	V425G	probably damaging	Het
Klk5	A	G	7: 43,850,822	N278S	probably damaging	Het
Mars2	T	A	1: 55,238,053	W272R	probably damaging	Het
Msl3l2	C	A	10: 56,115,921	S247R	possibly damaging	Het
Myh7	T	C	14: 54,979,468	E1144G	probably damaging	Het
Nefm	T	C	14: 68,120,239		probably benign	Het
Nwd2	A	G	5: 63,805,301	K743E	probably damaging	Het
Nyap2	C	T	1: 81,087,430	T53I	probably damaging	Het
Olfr1124	T	C	2: 87,435,324	V279A	probably benign	Het
Olfr617	T	C	7: 103,584,892	V290A	possibly damaging	Het
Peli2	A	G	14: 48,168,298	H60R	probably damaging	Het
Pias2	T	A	18: 77,145,148		probably benign	Het
Pik3c2b	A	G	1: 133,094,791	D1157G	probably damaging	Het
Pip4k2a	C	T	2: 18,866,111		probably null	Het
Raf1	A	T	6: 115,644,548	D23E	probably benign	Het
Rhox10	G	A	X: 38,066,856	R87H	probably benign	Het
Rpgrip1	A	G	14: 52,138,888	T449A	possibly damaging	Het
Serpina3a	T	A	12: 104,118,660	S105T	probably benign	Het
Slc12a9	T	G	5: 137,321,429	Q608P	probably damaging	Het
Smg6	C	A	11: 75,053,925	P167T	probably damaging	Het
Spata7	C	T	12: 98,634,260	T44I	probably damaging	Het
Spink12	C	T	18: 44,106,508		probably benign	Het
Srrm1	G	A	4: 135,325,104	P658L	unknown	Het
Stag2	C	T	X: 42,250,597	T754I	probably benign	Het
Supt6	C	T	11: 78,225,369	V723M	possibly damaging	Het
Ttc25	A	T	11: 100,566,983	N471Y	possibly damaging	Het
Ubr3	A	G	2: 69,948,488	D614G	possibly damaging	Het
Vps39	T	A	2: 120,323,608	K624N	probably benign	Het
Vwa5b1	A	T	4: 138,612,859	L29Q	probably damaging	Het
Wtap	G	A	17: 12,969,449	A188V	probably benign	Het
Zc3hc1	A	G	6: 30,390,975	F5L	probably benign	Het
Zfp655	C	T	5: 145,243,955	P208S	probably benign	Het
Zswim3	A	T	2: 164,820,682		probably null	Het

Other mutations in Antxrl

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01344:Antxrl	APN	14	34075597	missense	probably benign	0.01
IGL01632:Antxrl	APN	14	34067947	missense	probably damaging	0.99
IGL02381:Antxrl	APN	14	34056611	splice site	probably null
IGL02736:Antxrl	APN	14	34056618	unclassified	probably benign
R0631:Antxrl	UTSW	14	34058801	critical splice donor site	probably null
R1190:Antxrl	UTSW	14	34069250	missense	probably benign	0.00
R1406:Antxrl	UTSW	14	34073042	missense	possibly damaging	0.53
R1406:Antxrl	UTSW	14	34073042	missense	possibly damaging	0.53
R1454:Antxrl	UTSW	14	34060949	missense	probably damaging	0.99
R1469:Antxrl	UTSW	14	34067431	intron	probably benign
R1638:Antxrl	UTSW	14	34070496	critical splice donor site	probably null
R1996:Antxrl	UTSW	14	34075829	missense	probably benign	0.01
R2174:Antxrl	UTSW	14	34060400	missense	probably damaging	1.00
R2421:Antxrl	UTSW	14	34071689	intron	probably benign
R3850:Antxrl	UTSW	14	34067381	missense	probably benign	0.00
R4178:Antxrl	UTSW	14	34054971	splice site	probably null
R4434:Antxrl	UTSW	14	34071617	intron	probably benign
R4603:Antxrl	UTSW	14	34075835	missense	possibly damaging	0.72
R4769:Antxrl	UTSW	14	34073070	missense	possibly damaging	0.53
R6003:Antxrl	UTSW	14	34075635	missense	possibly damaging	0.72
R6047:Antxrl	UTSW	14	34053476	intron	probably benign
R6228:Antxrl	UTSW	14	34056599	missense	probably damaging	1.00
R6363:Antxrl	UTSW	14	34069287	missense	probably damaging	1.00
R6525:Antxrl	UTSW	14	34060406	missense	probably damaging	1.00
R6800:Antxrl	UTSW	14	34065907	missense	probably damaging	1.00
R6933:Antxrl	UTSW	14	34075771	missense	possibly damaging	0.53
R7086:Antxrl	UTSW	14	34065916	missense	probably benign	0.26
R7257:Antxrl	UTSW	14	34065849	missense	probably benign	0.03
R7315:Antxrl	UTSW	14	34071547	missense	unknown
R7981:Antxrl	UTSW	14	34065881	missense	probably damaging	0.99
R9070:Antxrl	UTSW	14	34071714	nonsense	probably null
R9097:Antxrl	UTSW	14	34071703	missense	probably benign	0.33
X0028:Antxrl	UTSW	14	34053915	critical splice donor site	probably null
Z1088:Antxrl	UTSW	14	34067971	missense	probably damaging	1.00
Z1177:Antxrl	UTSW	14	34067930	frame shift	probably null

Posted On

2015-04-16