Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02400:Gm10720'

291871

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm10720

Ensembl Gene

ENSMUSG00000074564

Gene Name

predicted gene 10720

Synonyms

Accession Numbers

Essential gene?

Not available question?

Stock #

IGL02400

Quality Score

Status

Chromosome

Chromosomal Location

3015654-3017210 bp(+) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

C to A at 3016900 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000136170 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000099047] [ENSMUST00000099049] [ENSMUST00000099050] [ENSMUST00000099050] [ENSMUST00000099050] [ENSMUST00000099050] [ENSMUST00000143083] [ENSMUST00000179272]

AlphaFold

D3Z1I5

Predicted Effect

probably null
Transcript: ENSMUST00000099047

SMART Domains

Protein: ENSMUSP00000096646
Gene: ENSMUSG00000095547

Domain	Start	End	E-Value	Type
internal_repeat_1	1	40	1.58e-10	PROSPERO
transmembrane domain	53	72	N/A	INTRINSIC
transmembrane domain	77	99	N/A	INTRINSIC
internal_repeat_1	117	176	1.58e-10	PROSPERO
transmembrane domain	199	221	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000099049

SMART Domains

Protein: ENSMUSP00000096648
Gene: ENSMUSG00000095547

Domain	Start	End	E-Value	Type
internal_repeat_1	1	46	2.19e-9	PROSPERO
transmembrane domain	62	84	N/A	INTRINSIC
internal_repeat_1	117	182	2.19e-9	PROSPERO
transmembrane domain	197	219	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000099050

SMART Domains

Protein: ENSMUSP00000096649
Gene: ENSMUSG00000074564

Domain	Start	End	E-Value	Type
internal_repeat_1	1	46	7.44e-11	PROSPERO
transmembrane domain	67	89	N/A	INTRINSIC
internal_repeat_1	117	182	7.44e-11	PROSPERO
transmembrane domain	192	214	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000099050

SMART Domains

Protein: ENSMUSP00000096649
Gene: ENSMUSG00000074564

Domain	Start	End	E-Value	Type
internal_repeat_1	1	46	7.44e-11	PROSPERO
transmembrane domain	67	89	N/A	INTRINSIC
internal_repeat_1	117	182	7.44e-11	PROSPERO
transmembrane domain	192	214	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000099050

SMART Domains

Protein: ENSMUSP00000096649
Gene: ENSMUSG00000074564

Domain	Start	End	E-Value	Type
internal_repeat_1	1	46	7.44e-11	PROSPERO
transmembrane domain	67	89	N/A	INTRINSIC
internal_repeat_1	117	182	7.44e-11	PROSPERO
transmembrane domain	192	214	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000099050

SMART Domains

Protein: ENSMUSP00000096649
Gene: ENSMUSG00000074564

Domain	Start	End	E-Value	Type
internal_repeat_1	1	46	7.44e-11	PROSPERO
transmembrane domain	67	89	N/A	INTRINSIC
internal_repeat_1	117	182	7.44e-11	PROSPERO
transmembrane domain	192	214	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000143083

SMART Domains

Protein: ENSMUSP00000137330
Gene: ENSMUSG00000096519

Domain	Start	End	E-Value	Type
internal_repeat_1	1	19	1.27e-7	PROSPERO
transmembrane domain	20	42	N/A	INTRINSIC
transmembrane domain	67	89	N/A	INTRINSIC
internal_repeat_1	117	135	1.27e-7	PROSPERO
transmembrane domain	155	177	N/A	INTRINSIC
transmembrane domain	192	214	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000179272

SMART Domains

Protein: ENSMUSP00000136170
Gene: ENSMUSG00000095547

Domain	Start	End	E-Value	Type
internal_repeat_1	1	49	2.1e-10	PROSPERO
transmembrane domain	74	96	N/A	INTRINSIC
internal_repeat_1	118	186	2.1e-10	PROSPERO
transmembrane domain	198	217	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000181242

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000181572

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 28 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2610028H24Rik	A	G	10: 76,290,644 (GRCm39)	I128V	possibly damaging	Het
Arfgef3	G	T	10: 18,522,005 (GRCm39)	Q674K	probably damaging	Het
Atp6v0a2	T	A	5: 124,798,849 (GRCm39)	N851K	probably benign	Het
Chrna7	A	G	7: 62,749,070 (GRCm39)	C471R	probably damaging	Het
Csgalnact1	C	A	8: 68,854,144 (GRCm39)	G219V	probably damaging	Het
Egflam	T	A	15: 7,276,534 (GRCm39)	K544M	probably benign	Het
Erbb3	A	C	10: 128,415,393 (GRCm39)	N385K	probably benign	Het
Fancm	A	G	12: 65,160,589 (GRCm39)	R1388G	probably damaging	Het
Gm20489	A	T	X: 100,306,944 (GRCm39)	N328K	possibly damaging	Het
Gm5828	G	T	1: 16,840,042 (GRCm39)		noncoding transcript	Het
Gnaq	T	C	19: 16,293,492 (GRCm39)	Y145H	probably damaging	Het
Itgbl1	A	G	14: 124,083,938 (GRCm39)	D148G	probably damaging	Het
Myc	T	G	15: 61,861,760 (GRCm39)		probably benign	Het
Or10d5	A	G	9: 39,861,635 (GRCm39)	V144A	probably benign	Het
Or5m3b	A	T	2: 85,872,420 (GRCm39)	I254F	probably benign	Het
Or6c211	A	G	10: 129,505,752 (GRCm39)	V212A	probably damaging	Het
Padi3	T	G	4: 140,516,179 (GRCm39)	K567T	probably benign	Het
Pi4ka	T	C	16: 17,111,748 (GRCm39)	T1576A	probably damaging	Het
Pikfyve	A	G	1: 65,291,728 (GRCm39)	R1316G	probably damaging	Het
Ryr2	A	G	13: 11,620,130 (GRCm39)		probably benign	Het
Sash1	G	A	10: 8,609,411 (GRCm39)	R713*	probably null	Het
Tmem214	G	A	5: 31,030,090 (GRCm39)	A296T	probably benign	Het
Tnfsf4	T	A	1: 161,223,276 (GRCm39)	C42S	possibly damaging	Het
Tpp1	A	G	7: 105,396,238 (GRCm39)	I487T	possibly damaging	Het
Trim43a	T	A	9: 88,464,165 (GRCm39)	N25K	probably benign	Het
Tuft1	T	C	3: 94,542,809 (GRCm39)		probably benign	Het
Usp46	T	C	5: 74,197,713 (GRCm39)	H26R	probably benign	Het
Zfp560	A	T	9: 20,261,896 (GRCm39)	I85N	possibly damaging	Het

Other mutations in Gm10720

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
R0153:Gm10720	UTSW	9	3,015,787 (GRCm39)	missense	probably null
V5622:Gm10720	UTSW	9	3,015,669 (GRCm39)	missense	probably benign

Posted On

2015-04-16