Incidental Mutation 'IGL02402:Gfod1'
ID 291923
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gfod1
Ensembl Gene ENSMUSG00000051335
Gene Name glucose-fructose oxidoreductase domain containing 1
Synonyms
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock # IGL02402
Quality Score
Status
Chromosome 13
Chromosomal Location 43195245-43304172 bp(-) (GRCm38)
Type of Mutation missense
DNA Base Change (assembly) C to A at 43200735 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change Alanine to Serine at position 255 (A255S)
Ref Sequence ENSEMBL: ENSMUSP00000062662 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000055341]
AlphaFold Q3UHD2
Predicted Effect probably benign
Transcript: ENSMUST00000055341
AA Change: A255S

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000062662
Gene: ENSMUSG00000051335
AA Change: A255S

DomainStartEndE-ValueType
Pfam:GFO_IDH_MocA 4 118 7.8e-13 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 45 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adgrv1 A G 13: 81,559,424 F568L probably benign Het
Arntl2 T C 6: 146,809,768 V90A possibly damaging Het
AW112010 T A 19: 11,048,377 noncoding transcript Het
Bbs4 A T 9: 59,330,446 L205H probably benign Het
C2cd2l T C 9: 44,316,581 K121R probably benign Het
Car14 A G 3: 95,899,558 V198A possibly damaging Het
Cd22 G T 7: 30,877,530 H117Q possibly damaging Het
Celf1 T A 2: 90,998,723 I45N probably damaging Het
Cluh T C 11: 74,657,171 S103P probably damaging Het
Cyp39a1 T A 17: 43,691,722 L276Q probably benign Het
Ddx27 T G 2: 167,015,325 probably benign Het
Defb4 A T 8: 19,201,263 I49F possibly damaging Het
Dock8 C A 19: 25,078,145 T157K probably benign Het
Dpp6 T C 5: 27,634,543 V352A probably damaging Het
Elmo2 C T 2: 165,297,392 E412K probably damaging Het
Eme1 G A 11: 94,650,907 P30S possibly damaging Het
Espnl G T 1: 91,344,813 A632S probably benign Het
Helz2 T A 2: 181,230,911 K2432M probably damaging Het
Idua T C 5: 108,679,791 L157P probably damaging Het
Ifi207 T A 1: 173,727,593 D848V probably damaging Het
Jag1 C T 2: 137,085,938 S851N possibly damaging Het
Kat6b T A 14: 21,631,347 F571I probably damaging Het
Lrrc74b G A 16: 17,558,164 probably benign Het
Mst1r A G 9: 107,916,827 K1160E probably damaging Het
Muc19 C A 15: 91,893,998 noncoding transcript Het
Nrg4 G A 9: 55,227,914 probably benign Het
Ociad1 T C 5: 73,300,694 I12T possibly damaging Het
Olfr98 A G 17: 37,263,220 V148A possibly damaging Het
Pold3 A G 7: 100,100,411 probably benign Het
Psmd5 T C 2: 34,857,772 E291G probably damaging Het
Ptpn23 A G 9: 110,393,713 V92A possibly damaging Het
Rab44 T A 17: 29,140,516 H559Q probably benign Het
Rbm6 T C 9: 107,852,852 D199G probably damaging Het
Rps18-ps3 C T 8: 107,263,122 noncoding transcript Het
Sept10 T C 10: 59,170,936 T93A probably benign Het
Slmap T C 14: 26,463,710 T111A probably damaging Het
Spata25 C T 2: 164,828,457 M1I probably null Het
Spink5 T A 18: 43,967,104 C63S probably damaging Het
Sycp3 T C 10: 88,466,563 probably benign Het
Tarbp1 A G 8: 126,450,828 probably benign Het
Thbs2 A T 17: 14,671,454 N940K probably benign Het
Tmem106b A T 6: 13,081,601 Q169L possibly damaging Het
Trpm6 G T 19: 18,786,756 C242F probably benign Het
Ush2a T A 1: 188,267,108 M205K probably benign Het
Utp18 A C 11: 93,883,791 probably benign Het
Other mutations in Gfod1
AlleleSourceChrCoordTypePredicted EffectPPH Score
R0483:Gfod1 UTSW 13 43200536 missense possibly damaging 0.75
R0959:Gfod1 UTSW 13 43303429 missense probably benign
R1913:Gfod1 UTSW 13 43303445 missense probably damaging 0.98
R1927:Gfod1 UTSW 13 43200860 missense possibly damaging 0.94
R2061:Gfod1 UTSW 13 43303243 critical splice donor site probably null
R2154:Gfod1 UTSW 13 43303470 missense possibly damaging 0.77
R2370:Gfod1 UTSW 13 43201145 missense probably benign 0.04
R3956:Gfod1 UTSW 13 43201062 missense probably damaging 0.98
R5061:Gfod1 UTSW 13 43200516 missense probably benign 0.01
R6090:Gfod1 UTSW 13 43200961 nonsense probably null
R6156:Gfod1 UTSW 13 43201038 missense possibly damaging 0.88
R6573:Gfod1 UTSW 13 43200365 missense probably damaging 0.99
R7692:Gfod1 UTSW 13 43201052 missense probably benign 0.00
R8353:Gfod1 UTSW 13 43200890 missense possibly damaging 0.82
R9063:Gfod1 UTSW 13 43200804 missense probably benign 0.35
R9087:Gfod1 UTSW 13 43200362 missense probably damaging 0.96
R9090:Gfod1 UTSW 13 43303385 missense possibly damaging 0.92
R9271:Gfod1 UTSW 13 43303385 missense possibly damaging 0.92
R9380:Gfod1 UTSW 13 43200844 missense probably damaging 1.00
Posted On 2015-04-16