Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL02406:Vmn2r32'

292056

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r32

Ensembl Gene

ENSMUSG00000096743

Gene Name

vomeronasal 2, receptor 32

Synonyms

V2r5

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.144) question?

Stock #

IGL02406

Quality Score

Status

Chromosome

Chromosomal Location

7463015-7479973 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 7476710 bp

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Histidine at position 155 (Y155H)

Ref Sequence

ENSEMBL: ENSMUSP00000092462 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000094866]

Predicted Effect

probably benign
Transcript: ENSMUST00000094866
AA Change: Y155H

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000092462
Gene: ENSMUSG00000096743
AA Change: Y155H

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC
Pfam:ANF_receptor	73	470	3.6e-33	PFAM
Pfam:NCD3G	512	565	8.1e-21	PFAM
Pfam:7tm_3	598	833	9.5e-55	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 43 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca16	G	T	7: 120,540,602	A1496S	probably damaging	Het
Abra	A	T	15: 41,869,187	V161E	probably damaging	Het
Adcy4	G	A	14: 55,770,047	T942I	possibly damaging	Het
Atrip	A	G	9: 109,065,419	V480A	probably damaging	Het
Azin1	A	T	15: 38,491,565	D382E	probably benign	Het
BC034090	G	T	1: 155,225,153	A455E	probably benign	Het
Clstn1	A	G	4: 149,627,359	Y121C	probably damaging	Het
Cpq	T	A	15: 33,302,508	N268K	probably damaging	Het
Cpsf7	A	G	19: 10,531,988	S88G	probably damaging	Het
Csgalnact1	C	A	8: 68,401,492	G219V	probably damaging	Het
Cyp2j11	G	A	4: 96,348,539	A10V	possibly damaging	Het
Dock4	T	C	12: 40,777,207	V983A	probably benign	Het
Dspp	G	T	5: 104,177,366	E532*	probably null	Het
Ercc4	G	T	16: 13,123,536	D243Y	probably damaging	Het
Fars2	C	A	13: 36,410,162	D383E	probably benign	Het
Fip1l1	A	G	5: 74,564,544	T280A	probably benign	Het
Gcgr	T	G	11: 120,537,184	N292K	probably damaging	Het
Gtpbp4	T	A	13: 8,991,750	K85M	possibly damaging	Het
Jhy	A	G	9: 40,910,989	Y618H	probably damaging	Het
Mbd4	A	T	6: 115,849,025	I314N	possibly damaging	Het
Mbtd1	C	T	11: 93,908,858	T70M	probably damaging	Het
Mki67	T	C	7: 135,698,793	H1504R	probably benign	Het
Mks1	T	C	11: 87,862,785	V515A	probably benign	Het
Msantd2	G	T	9: 37,523,459	V332L	probably damaging	Het
Myrip	A	T	9: 120,467,532	T836S	probably benign	Het
Nbea	T	C	3: 56,086,266	I238V	probably benign	Het
Plekhh1	T	C	12: 79,069,009		probably benign	Het
Prkdc	A	G	16: 15,670,535	N507S	probably benign	Het
Prss12	G	A	3: 123,505,474	V632I	possibly damaging	Het
Puf60	A	G	15: 76,074,609	S121P	probably damaging	Het
Raet1e	G	A	10: 22,180,636	C37Y	probably damaging	Het
Ralgps2	G	T	1: 156,828,268	A362E	possibly damaging	Het
Scn1a	A	G	2: 66,326,036	S510P	possibly damaging	Het
Skap2	A	C	6: 51,874,473		probably null	Het
Slc4a10	G	A	2: 62,190,769	V54M	probably benign	Het
Spata17	A	G	1: 187,117,261		probably null	Het
Stoml3	T	A	3: 53,503,250	N128K	probably damaging	Het
Tatdn2	T	A	6: 113,704,213	S402R	probably benign	Het
Tmprss11f	A	G	5: 86,533,666	W243R	probably damaging	Het
Vmn2r86	T	A	10: 130,448,639	T528S	possibly damaging	Het
Zfhx3	C	T	8: 108,955,742	A3271V	unknown	Het
Zkscan3	T	C	13: 21,388,178	N428S	possibly damaging	Het
Zxdc	A	G	6: 90,398,836	S765G	probably benign	Het

Other mutations in Vmn2r32

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02140:Vmn2r32	APN	7	7476697	missense	probably damaging	0.97
IGL02333:Vmn2r32	APN	7	7464144	missense	probably damaging	1.00
IGL02428:Vmn2r32	APN	7	7474284	missense	probably benign	0.02
IGL02484:Vmn2r32	APN	7	7464117	missense	probably damaging	1.00
IGL03277:Vmn2r32	APN	7	7474252	missense	probably benign	0.23
IGL03366:Vmn2r32	APN	7	7464030	missense	probably damaging	0.99
R1055:Vmn2r32	UTSW	7	7474327	nonsense	probably null
R1695:Vmn2r32	UTSW	7	7463992	missense	probably benign	0.01
R2172:Vmn2r32	UTSW	7	7474615	missense	probably damaging	0.99
R2262:Vmn2r32	UTSW	7	7474619	missense	probably benign
R3150:Vmn2r32	UTSW	7	7472555	missense	probably benign
R4362:Vmn2r32	UTSW	7	7479858	nonsense	probably null
R4432:Vmn2r32	UTSW	7	7479919	missense	probably damaging	0.98
R4851:Vmn2r32	UTSW	7	7479954	missense	possibly damaging	0.59
R4949:Vmn2r32	UTSW	7	7464084	missense	probably benign	0.22
R5990:Vmn2r32	UTSW	7	7479810	missense	probably damaging	0.97
R6083:Vmn2r32	UTSW	7	7464210	missense	probably benign	0.15
R6084:Vmn2r32	UTSW	7	7464210	missense	probably benign	0.15
R6116:Vmn2r32	UTSW	7	7464093	missense	probably damaging	1.00
R6263:Vmn2r32	UTSW	7	7476692	missense	possibly damaging	0.90
R6889:Vmn2r32	UTSW	7	7472574	missense	possibly damaging	0.82
R7286:Vmn2r32	UTSW	7	7479808	missense	probably benign	0.21
R7390:Vmn2r32	UTSW	7	7479852	missense	probably benign	0.00
R7412:Vmn2r32	UTSW	7	7474213	missense	possibly damaging	0.53
R7508:Vmn2r32	UTSW	7	7467374	missense	possibly damaging	0.87
Z1177:Vmn2r32	UTSW	7	7474161	missense	probably damaging	0.98

Posted On

2015-04-16