Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02406:Vmn2r32'

292056

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r32

Ensembl Gene

ENSMUSG00000096743

Gene Name

vomeronasal 2, receptor 32

Synonyms

V2r5

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.190) question?

Stock #

IGL02406

Quality Score

Status

Chromosome

Chromosomal Location

7463015-7479973 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 7476710 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Histidine at position 155 (Y155H)

Ref Sequence

ENSEMBL: ENSMUSP00000092462 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000094866]

AlphaFold

K7N686

Predicted Effect

probably benign
Transcript: ENSMUST00000094866
AA Change: Y155H

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000092462
Gene: ENSMUSG00000096743
AA Change: Y155H

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC
Pfam:ANF_receptor	73	470	3.6e-33	PFAM
Pfam:NCD3G	512	565	8.1e-21	PFAM
Pfam:7tm_3	598	833	9.5e-55	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 43 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca16	G	T	7: 120,540,602 (GRCm38)	A1496S	probably damaging	Het
Abra	A	T	15: 41,869,187 (GRCm38)	V161E	probably damaging	Het
Adcy4	G	A	14: 55,770,047 (GRCm38)	T942I	possibly damaging	Het
Atrip	A	G	9: 109,065,419 (GRCm38)	V480A	probably damaging	Het
Azin1	A	T	15: 38,491,565 (GRCm38)	D382E	probably benign	Het
BC034090	G	T	1: 155,225,153 (GRCm38)	A455E	probably benign	Het
Clstn1	A	G	4: 149,627,359 (GRCm38)	Y121C	probably damaging	Het
Cpq	T	A	15: 33,302,508 (GRCm38)	N268K	probably damaging	Het
Cpsf7	A	G	19: 10,531,988 (GRCm38)	S88G	probably damaging	Het
Csgalnact1	C	A	8: 68,401,492 (GRCm38)	G219V	probably damaging	Het
Cyp2j11	G	A	4: 96,348,539 (GRCm38)	A10V	possibly damaging	Het
Dock4	T	C	12: 40,777,207 (GRCm38)	V983A	probably benign	Het
Dspp	G	T	5: 104,177,366 (GRCm38)	E532*	probably null	Het
Ercc4	G	T	16: 13,123,536 (GRCm38)	D243Y	probably damaging	Het
Fars2	C	A	13: 36,410,162 (GRCm38)	D383E	probably benign	Het
Fip1l1	A	G	5: 74,564,544 (GRCm38)	T280A	probably benign	Het
Gcgr	T	G	11: 120,537,184 (GRCm38)	N292K	probably damaging	Het
Gtpbp4	T	A	13: 8,991,750 (GRCm38)	K85M	possibly damaging	Het
Jhy	A	G	9: 40,910,989 (GRCm38)	Y618H	probably damaging	Het
Mbd4	A	T	6: 115,849,025 (GRCm38)	I314N	possibly damaging	Het
Mbtd1	C	T	11: 93,908,858 (GRCm38)	T70M	probably damaging	Het
Mki67	T	C	7: 135,698,793 (GRCm38)	H1504R	probably benign	Het
Mks1	T	C	11: 87,862,785 (GRCm38)	V515A	probably benign	Het
Msantd2	G	T	9: 37,523,459 (GRCm38)	V332L	probably damaging	Het
Myrip	A	T	9: 120,467,532 (GRCm38)	T836S	probably benign	Het
Nbea	T	C	3: 56,086,266 (GRCm38)	I238V	probably benign	Het
Plekhh1	T	C	12: 79,069,009 (GRCm38)		probably benign	Het
Prkdc	A	G	16: 15,670,535 (GRCm38)	N507S	probably benign	Het
Prss12	G	A	3: 123,505,474 (GRCm38)	V632I	possibly damaging	Het
Puf60	A	G	15: 76,074,609 (GRCm38)	S121P	probably damaging	Het
Raet1e	G	A	10: 22,180,636 (GRCm38)	C37Y	probably damaging	Het
Ralgps2	G	T	1: 156,828,268 (GRCm38)	A362E	possibly damaging	Het
Scn1a	A	G	2: 66,326,036 (GRCm38)	S510P	possibly damaging	Het
Skap2	A	C	6: 51,874,473 (GRCm38)		probably null	Het
Slc4a10	G	A	2: 62,190,769 (GRCm38)	V54M	probably benign	Het
Spata17	A	G	1: 187,117,261 (GRCm38)		probably null	Het
Stoml3	T	A	3: 53,503,250 (GRCm38)	N128K	probably damaging	Het
Tatdn2	T	A	6: 113,704,213 (GRCm38)	S402R	probably benign	Het
Tmprss11f	A	G	5: 86,533,666 (GRCm38)	W243R	probably damaging	Het
Vmn2r86	T	A	10: 130,448,639 (GRCm38)	T528S	possibly damaging	Het
Zfhx3	C	T	8: 108,955,742 (GRCm38)	A3271V	unknown	Het
Zkscan3	T	C	13: 21,388,178 (GRCm38)	N428S	possibly damaging	Het
Zxdc	A	G	6: 90,398,836 (GRCm38)	S765G	probably benign	Het

Other mutations in Vmn2r32

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02140:Vmn2r32	APN	7	7,476,697 (GRCm38)	missense	probably damaging	0.97
IGL02333:Vmn2r32	APN	7	7,464,144 (GRCm38)	missense	probably damaging	1.00
IGL02428:Vmn2r32	APN	7	7,474,284 (GRCm38)	missense	probably benign	0.02
IGL02484:Vmn2r32	APN	7	7,464,117 (GRCm38)	missense	probably damaging	1.00
IGL03277:Vmn2r32	APN	7	7,474,252 (GRCm38)	missense	probably benign	0.23
IGL03366:Vmn2r32	APN	7	7,464,030 (GRCm38)	missense	probably damaging	0.99
R1055:Vmn2r32	UTSW	7	7,474,327 (GRCm38)	nonsense	probably null
R1695:Vmn2r32	UTSW	7	7,463,992 (GRCm38)	missense	probably benign	0.01
R2172:Vmn2r32	UTSW	7	7,474,615 (GRCm38)	missense	probably damaging	0.99
R2262:Vmn2r32	UTSW	7	7,474,619 (GRCm38)	missense	probably benign
R3150:Vmn2r32	UTSW	7	7,472,555 (GRCm38)	missense	probably benign
R4362:Vmn2r32	UTSW	7	7,479,858 (GRCm38)	nonsense	probably null
R4432:Vmn2r32	UTSW	7	7,479,919 (GRCm38)	missense	probably damaging	0.98
R4851:Vmn2r32	UTSW	7	7,479,954 (GRCm38)	missense	possibly damaging	0.59
R4949:Vmn2r32	UTSW	7	7,464,084 (GRCm38)	missense	probably benign	0.22
R5990:Vmn2r32	UTSW	7	7,479,810 (GRCm38)	missense	probably damaging	0.97
R6083:Vmn2r32	UTSW	7	7,464,210 (GRCm38)	missense	probably benign	0.15
R6084:Vmn2r32	UTSW	7	7,464,210 (GRCm38)	missense	probably benign	0.15
R6116:Vmn2r32	UTSW	7	7,464,093 (GRCm38)	missense	probably damaging	1.00
R6263:Vmn2r32	UTSW	7	7,476,692 (GRCm38)	missense	possibly damaging	0.90
R6889:Vmn2r32	UTSW	7	7,472,574 (GRCm38)	missense	possibly damaging	0.82
R7286:Vmn2r32	UTSW	7	7,479,808 (GRCm38)	missense	probably benign	0.21
R7390:Vmn2r32	UTSW	7	7,479,852 (GRCm38)	missense	probably benign	0.00
R7412:Vmn2r32	UTSW	7	7,474,213 (GRCm38)	missense	possibly damaging	0.53
R7508:Vmn2r32	UTSW	7	7,467,374 (GRCm38)	missense	possibly damaging	0.87
R8812:Vmn2r32	UTSW	7	7,474,670 (GRCm38)	missense	probably damaging	1.00
R8968:Vmn2r32	UTSW	7	7,474,205 (GRCm38)	missense	probably benign	0.00
R9331:Vmn2r32	UTSW	7	7,464,403 (GRCm38)	nonsense	probably null
R9358:Vmn2r32	UTSW	7	7,474,198 (GRCm38)	missense	probably damaging	1.00
Z1177:Vmn2r32	UTSW	7	7,474,161 (GRCm38)	missense	probably damaging	0.98

Posted On

2015-04-16