Incidental Mutation 'IGL02414:Trim43c'
ID292378
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Trim43c
Ensembl Gene ENSMUSG00000067399
Gene Nametripartite motif-containing 43C
SynonymsTrim43
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.080) question?
Stock #IGL02414
Quality Score
Status
Chromosome9
Chromosomal Location88839164-88848190 bp(+) (GRCm38)
Type of Mutationcritical splice acceptor site
DNA Base Change (assembly) A to T at 88841832 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000139715 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000163255] [ENSMUST00000186363]
Predicted Effect probably null
Transcript: ENSMUST00000163255
SMART Domains Protein: ENSMUSP00000129255
Gene: ENSMUSG00000067399

DomainStartEndE-ValueType
RING 16 56 3.34e-6 SMART
PDB:2IWG|E 329 446 3e-15 PDB
Blast:SPRY 336 441 3e-20 BLAST
Predicted Effect noncoding transcript
Transcript: ENSMUST00000180712
Predicted Effect noncoding transcript
Transcript: ENSMUST00000180783
Predicted Effect probably null
Transcript: ENSMUST00000186363
SMART Domains Protein: ENSMUSP00000139715
Gene: ENSMUSG00000067399

DomainStartEndE-ValueType
RING 16 56 1.6e-8 SMART
SPRY 334 445 6e-4 SMART
Predicted Effect noncoding transcript
Transcript: ENSMUST00000188156
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 24 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
9230104L09Rik T G 2: 148,850,678 K68T possibly damaging Het
Ada C T 2: 163,730,040 D273N probably benign Het
Btbd9 A C 17: 30,220,559 C551W possibly damaging Het
Casp2 T A 6: 42,280,446 L443H probably damaging Het
Cdhr3 A G 12: 33,042,504 Y703H possibly damaging Het
Clta T C 4: 44,030,274 probably benign Het
Dnah8 A G 17: 30,700,413 D1120G probably benign Het
Ece2 A G 16: 20,640,706 D597G probably damaging Het
Etfdh A G 3: 79,604,096 V526A probably damaging Het
Gm14496 T A 2: 181,991,405 D60E probably benign Het
Gpr85 A T 6: 13,836,910 probably benign Het
Hivep1 C A 13: 42,154,909 S208R probably damaging Het
Kif1b A G 4: 149,199,314 I1252T probably damaging Het
Knl1 T C 2: 119,070,323 V835A possibly damaging Het
Olfr209 C T 16: 59,361,714 C168Y probably damaging Het
Olfr710 A T 7: 106,944,758 M81K probably benign Het
Ppwd1 T G 13: 104,223,137 I119L probably benign Het
Prex1 T C 2: 166,609,828 K410R probably damaging Het
Prm2 C T 16: 10,791,890 probably benign Het
Psip1 T C 4: 83,468,637 T166A probably benign Het
Rtel1 T C 2: 181,335,972 V98A probably benign Het
Sdsl G A 5: 120,462,059 T91I probably damaging Het
Tas2r136 A G 6: 132,777,531 M211T possibly damaging Het
Ttc1 T C 11: 43,739,837 probably benign Het
Other mutations in Trim43c
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00780:Trim43c APN 9 88841856 missense probably benign 0.20
R0054:Trim43c UTSW 9 88847515 missense probably damaging 1.00
R0765:Trim43c UTSW 9 88841916 missense probably benign 0.28
R0862:Trim43c UTSW 9 88843034 missense probably benign 0.01
R0864:Trim43c UTSW 9 88843034 missense probably benign 0.01
R1117:Trim43c UTSW 9 88844977 missense probably benign 0.20
R1222:Trim43c UTSW 9 88843078 missense possibly damaging 0.70
R1643:Trim43c UTSW 9 88847477 missense probably damaging 0.97
R1691:Trim43c UTSW 9 88840699 missense probably damaging 0.98
R1914:Trim43c UTSW 9 88840617 missense probably benign 0.01
R3718:Trim43c UTSW 9 88844977 missense probably benign 0.20
R3772:Trim43c UTSW 9 88847757 missense probably damaging 1.00
R3852:Trim43c UTSW 9 88840401 missense probably damaging 1.00
R4774:Trim43c UTSW 9 88847652 missense possibly damaging 0.48
R5784:Trim43c UTSW 9 88847643 missense probably benign 0.03
R5833:Trim43c UTSW 9 88843037 missense possibly damaging 0.74
R6177:Trim43c UTSW 9 88840547 missense possibly damaging 0.50
R6407:Trim43c UTSW 9 88840414 missense probably benign
R6490:Trim43c UTSW 9 88844950 missense possibly damaging 0.50
R6892:Trim43c UTSW 9 88844924 missense probably benign 0.35
R8050:Trim43c UTSW 9 88840337 missense probably damaging 0.99
Z1088:Trim43c UTSW 9 88842935 critical splice acceptor site probably null
Posted On2015-04-16