Incidental Mutation 'IGL00900:Vmn1r232'
| ID |
29239 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Vmn1r232
|
| Ensembl Gene |
ENSMUSG00000062165 |
| Gene Name |
vomeronasal 1 receptor 232 |
| Synonyms |
V1re4 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.056)
|
| Stock # |
IGL00900
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
17 |
| Chromosomal Location |
21133467-21134625 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 21134394 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Leucine
at position 69
(F69L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000076261
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000077001]
|
| AlphaFold |
A2RTT5 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000077001
AA Change: F69L
PolyPhen 2
Score 0.069 (Sensitivity: 0.94; Specificity: 0.84)
|
| SMART Domains |
Protein: ENSMUSP00000076261
Gene: ENSMUSG00000062165
AA Change: F69L
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TAS2R
|
46 |
331 |
6.9e-7 |
PFAM |
|
Pfam:7tm_1
|
70 |
324 |
1e-6 |
PFAM |
|
Pfam:V1R
|
78 |
338 |
1.9e-29 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000232004
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 32 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aatf |
T |
C |
11: 84,361,383 (GRCm39) |
|
probably benign |
Het |
| Agap3 |
G |
A |
5: 24,681,366 (GRCm39) |
|
probably benign |
Het |
| Angptl2 |
A |
T |
2: 33,133,784 (GRCm39) |
M369L |
probably benign |
Het |
| Arhgef11 |
A |
G |
3: 87,590,867 (GRCm39) |
D36G |
possibly damaging |
Het |
| Ccnt1 |
A |
G |
15: 98,452,514 (GRCm39) |
V134A |
probably damaging |
Het |
| Ces1e |
T |
C |
8: 93,944,245 (GRCm39) |
H191R |
probably damaging |
Het |
| Dhh |
A |
G |
15: 98,796,101 (GRCm39) |
|
probably benign |
Het |
| Edil3 |
C |
A |
13: 89,437,652 (GRCm39) |
H418N |
probably benign |
Het |
| Fam161b |
T |
C |
12: 84,402,743 (GRCm39) |
I296V |
probably benign |
Het |
| Focad |
T |
A |
4: 88,047,260 (GRCm39) |
N86K |
probably damaging |
Het |
| Foxn1 |
C |
T |
11: 78,262,109 (GRCm39) |
G87S |
probably benign |
Het |
| Glipr1l2 |
T |
C |
10: 111,933,887 (GRCm39) |
Y220H |
probably benign |
Het |
| Hnrnpa1 |
A |
G |
15: 103,152,166 (GRCm39) |
|
probably benign |
Het |
| Hnrnpm |
C |
A |
17: 33,868,876 (GRCm39) |
R517L |
probably damaging |
Het |
| Ipo11 |
T |
C |
13: 106,983,952 (GRCm39) |
M797V |
possibly damaging |
Het |
| Itprid2 |
G |
A |
2: 79,490,822 (GRCm39) |
R980Q |
probably damaging |
Het |
| Klhdc2 |
T |
A |
12: 69,350,308 (GRCm39) |
F118I |
probably benign |
Het |
| Mtap |
T |
A |
4: 89,090,594 (GRCm39) |
Y221* |
probably null |
Het |
| Myh2 |
T |
C |
11: 67,070,210 (GRCm39) |
V414A |
probably damaging |
Het |
| Ncor2 |
A |
T |
5: 125,102,848 (GRCm39) |
Y1999N |
probably damaging |
Het |
| Or5d39 |
A |
G |
2: 87,979,604 (GRCm39) |
F253S |
possibly damaging |
Het |
| Oxsm |
A |
G |
14: 16,242,023 (GRCm38) |
S249P |
probably damaging |
Het |
| Pabpc4l |
T |
A |
3: 46,401,507 (GRCm39) |
I46F |
possibly damaging |
Het |
| Pcnx2 |
A |
G |
8: 126,589,975 (GRCm39) |
|
probably benign |
Het |
| Rasal2 |
A |
G |
1: 157,239,499 (GRCm39) |
S4P |
possibly damaging |
Het |
| Reln |
A |
G |
5: 22,185,115 (GRCm39) |
V1534A |
probably damaging |
Het |
| Rnf138 |
T |
A |
18: 21,154,017 (GRCm39) |
D174E |
possibly damaging |
Het |
| Sh3pxd2a |
T |
A |
19: 47,302,594 (GRCm39) |
N162Y |
probably benign |
Het |
| Slc6a4 |
A |
T |
11: 76,914,006 (GRCm39) |
T519S |
probably benign |
Het |
| Slfn9 |
A |
T |
11: 82,872,197 (GRCm39) |
C846* |
probably null |
Het |
| Trip12 |
A |
G |
1: 84,702,485 (GRCm39) |
S1945P |
possibly damaging |
Het |
| Zeb2 |
T |
C |
2: 44,887,287 (GRCm39) |
D545G |
probably damaging |
Het |
|
| Other mutations in Vmn1r232 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL02576:Vmn1r232
|
APN |
17 |
21,134,175 (GRCm39) |
missense |
probably benign |
0.30 |
|
H8562:Vmn1r232
|
UTSW |
17 |
21,133,656 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1182:Vmn1r232
|
UTSW |
17 |
21,133,705 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R2010:Vmn1r232
|
UTSW |
17 |
21,133,601 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2088:Vmn1r232
|
UTSW |
17 |
21,133,999 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R2206:Vmn1r232
|
UTSW |
17 |
21,134,465 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2207:Vmn1r232
|
UTSW |
17 |
21,134,465 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2273:Vmn1r232
|
UTSW |
17 |
21,134,465 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2274:Vmn1r232
|
UTSW |
17 |
21,134,465 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2275:Vmn1r232
|
UTSW |
17 |
21,134,465 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2443:Vmn1r232
|
UTSW |
17 |
21,133,646 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2516:Vmn1r232
|
UTSW |
17 |
21,134,288 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R3700:Vmn1r232
|
UTSW |
17 |
21,134,465 (GRCm39) |
missense |
probably benign |
0.29 |
|
R5256:Vmn1r232
|
UTSW |
17 |
21,133,846 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5418:Vmn1r232
|
UTSW |
17 |
21,134,378 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5726:Vmn1r232
|
UTSW |
17 |
21,133,601 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5833:Vmn1r232
|
UTSW |
17 |
21,133,913 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6528:Vmn1r232
|
UTSW |
17 |
21,134,309 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7019:Vmn1r232
|
UTSW |
17 |
21,133,547 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R7600:Vmn1r232
|
UTSW |
17 |
21,133,999 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R8377:Vmn1r232
|
UTSW |
17 |
21,134,239 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8695:Vmn1r232
|
UTSW |
17 |
21,134,109 (GRCm39) |
missense |
probably benign |
|
|
R9000:Vmn1r232
|
UTSW |
17 |
21,134,111 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9512:Vmn1r232
|
UTSW |
17 |
21,134,416 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1088:Vmn1r232
|
UTSW |
17 |
21,134,100 (GRCm39) |
missense |
probably benign |
0.38 |
|
| Posted On |
2013-04-17 |
Incidental Mutation