Incidental Mutation 'IGL02421:Vmn1r54'
ID292654
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r54
Ensembl Gene ENSMUSG00000047203
Gene Namevomeronasal 1 receptor 54
SynonymsV1ra9, VN7
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.055) question?
Stock #IGL02421
Quality Score
Status
Chromosome6
Chromosomal Location90246300-90271213 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) G to A at 90269151 bp
ZygosityHeterozygous
Amino Acid Change Alanine to Threonine at position 16 (A16T)
Ref Sequence ENSEMBL: ENSMUSP00000154354 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000058039] [ENSMUST00000226921]
Predicted Effect probably benign
Transcript: ENSMUST00000058039
AA Change: A16T

PolyPhen 2 Score 0.009 (Sensitivity: 0.96; Specificity: 0.77)
SMART Domains Protein: ENSMUSP00000063052
Gene: ENSMUSG00000047203
AA Change: A16T

DomainStartEndE-ValueType
Pfam:TAS2R 11 307 1.2e-11 PFAM
Pfam:V1R 38 301 5.5e-94 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000226921
AA Change: A16T

PolyPhen 2 Score 0.009 (Sensitivity: 0.96; Specificity: 0.77)
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 45 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
a T C 2: 155,050,752 F117S probably damaging Het
A930011G23Rik A G 5: 99,229,377 S404P probably damaging Het
A930011G23Rik G A 5: 99,229,382 P402L probably damaging Het
Acacb A G 5: 114,223,878 T1394A probably benign Het
Adam19 A G 11: 46,137,553 N671S probably damaging Het
Akap13 A T 7: 75,717,806 N1815I possibly damaging Het
Aloxe3 A G 11: 69,130,046 D199G possibly damaging Het
Ap1g2 G A 14: 55,102,402 A440V probably damaging Het
Bmt2 G T 6: 13,628,842 Q281K probably damaging Het
Celsr3 T C 9: 108,840,463 F2243L probably damaging Het
Cenpb G A 2: 131,179,681 R66C probably damaging Het
Chl1 A T 6: 103,717,580 H1121L probably damaging Het
Cpb1 T C 3: 20,251,984 Y344C probably damaging Het
Cspg5 T A 9: 110,247,392 probably benign Het
Dnah11 T C 12: 118,186,902 N374D probably damaging Het
Dnah3 A G 7: 119,950,992 V3368A possibly damaging Het
Eml4 T C 17: 83,477,892 S829P probably benign Het
Gm14548 T C 7: 3,896,995 N203D possibly damaging Het
Got2-ps1 T C 5: 138,364,549 noncoding transcript Het
Hal T C 10: 93,503,473 C475R probably damaging Het
Mapkbp1 C T 2: 120,019,655 P806S possibly damaging Het
Mmrn1 A T 6: 60,944,822 T88S probably benign Het
Napsa A G 7: 44,585,055 H237R probably damaging Het
Olfr1215 T C 2: 89,001,344 probably null Het
Olfr412 T C 11: 74,365,191 I174T probably damaging Het
Olfr568 T C 7: 102,877,759 I213T probably damaging Het
Olfr661 A G 7: 104,688,533 N173D probably benign Het
Opn5 C T 17: 42,596,555 probably benign Het
Polb C T 8: 22,640,373 G179D probably damaging Het
Primpol G T 8: 46,607,795 probably benign Het
Prom2 T A 2: 127,531,882 probably null Het
Psmb10 A G 8: 105,937,492 probably null Het
Ranbp2 T G 10: 58,480,554 S2365R probably damaging Het
Sgce G A 6: 4,694,187 probably benign Het
Slc25a34 A G 4: 141,621,442 V237A probably benign Het
Slc39a2 A T 14: 51,893,872 T25S probably benign Het
Smarca4 T C 9: 21,639,239 C423R probably damaging Het
Stt3b G A 9: 115,251,852 probably benign Het
Tbl1xr1 A T 3: 22,203,163 I397F probably damaging Het
Tie1 A G 4: 118,486,394 V117A probably damaging Het
Tmc3 T C 7: 83,622,744 F1035L probably benign Het
Trhde T A 10: 114,412,461 K944N probably damaging Het
Washc4 T A 10: 83,579,550 N801K probably damaging Het
Xylt2 A G 11: 94,667,762 Y523H possibly damaging Het
Znfx1 T C 2: 167,060,080 R5G probably damaging Het
Other mutations in Vmn1r54
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01912:Vmn1r54 APN 6 90269460 missense probably damaging 1.00
IGL02535:Vmn1r54 APN 6 90269278 missense possibly damaging 0.78
IGL03083:Vmn1r54 APN 6 90269872 missense possibly damaging 0.82
R0646:Vmn1r54 UTSW 6 90269653 missense probably benign 0.00
R2047:Vmn1r54 UTSW 6 90269988 missense probably damaging 1.00
R4409:Vmn1r54 UTSW 6 90269882 nonsense probably null
R4467:Vmn1r54 UTSW 6 90269271 missense probably damaging 1.00
R4812:Vmn1r54 UTSW 6 90269325 missense probably benign 0.22
R5042:Vmn1r54 UTSW 6 90269440 missense possibly damaging 0.53
R5555:Vmn1r54 UTSW 6 90269365 missense probably benign 0.02
R6183:Vmn1r54 UTSW 6 90269290 missense possibly damaging 0.61
R6393:Vmn1r54 UTSW 6 90269322 missense probably benign 0.45
R7216:Vmn1r54 UTSW 6 90269665 missense probably damaging 1.00
R7480:Vmn1r54 UTSW 6 90269178 missense possibly damaging 0.58
R8413:Vmn1r54 UTSW 6 90269431 missense probably damaging 1.00
Posted On2015-04-16