Incidental Mutation 'IGL02426:Rtl9'
ID292920
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Rtl9
Ensembl Gene ENSMUSG00000085584
Gene Nameretrotransposon Gag like 9
SynonymsMar9, Rgag1, Mart9
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.140) question?
Stock #IGL02426
Quality Score
Status
ChromosomeX
Chromosomal Location143099594-143104297 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to C at 143103102 bp
ZygosityHeterozygous
Amino Acid Change Valine to Alanine at position 1170 (V1170A)
Ref Sequence ENSEMBL: ENSMUSP00000128287 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000165829]
Predicted Effect probably damaging
Transcript: ENSMUST00000165829
AA Change: V1170A

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000128287
Gene: ENSMUSG00000085584
AA Change: V1170A

DomainStartEndE-ValueType
internal_repeat_2 24 411 4.71e-5 PROSPERO
internal_repeat_1 56 459 4.41e-9 PROSPERO
internal_repeat_2 608 1036 4.71e-5 PROSPERO
internal_repeat_1 700 1107 4.41e-9 PROSPERO
low complexity region 1144 1153 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 35 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abcc5 G A 16: 20,338,925 T1294M probably damaging Het
Bad A G 19: 6,951,417 S128G probably damaging Het
Casp9 T G 4: 141,812,204 probably null Het
Ccdc39 T C 3: 33,825,398 K507R possibly damaging Het
Cep76 A G 18: 67,634,917 S182P probably benign Het
Cmtr2 A G 8: 110,221,690 M211V possibly damaging Het
Cobl T A 11: 12,254,351 K777* probably null Het
Cul9 T G 17: 46,523,258 T1253P possibly damaging Het
Dmd T A X: 84,848,736 L3002H probably damaging Het
Dnah9 C T 11: 66,125,153 V421I probably benign Het
Eif4a2 A G 16: 23,110,649 I234V probably benign Het
Epha4 T C 1: 77,444,877 M323V probably benign Het
Fam47c A G X: 78,738,337 D175G probably benign Het
Gm13101 T C 4: 143,966,659 D83G possibly damaging Het
Gm14178 T C 11: 99,747,515 Het
Gpr1 T C 1: 63,183,668 Y136C probably damaging Het
Hes3 T C 4: 152,286,940 N184S probably benign Het
Kdm6a A G X: 18,246,310 E45G probably damaging Het
Kdr T C 5: 75,974,466 K33E probably benign Het
Olfr1097 A G 2: 86,890,620 L185S probably damaging Het
Olfr1281 A T 2: 111,328,575 D52V probably damaging Het
Olfr1295 A T 2: 111,564,538 I302K probably benign Het
Olfr437 A C 6: 43,167,088 D10A probably benign Het
Olfr503 A G 7: 108,544,980 T150A probably benign Het
Pi4ka A T 16: 17,378,432 probably benign Het
Pigk T A 3: 152,742,483 probably null Het
Pikfyve A G 1: 65,251,612 T1197A possibly damaging Het
Plppr4 T C 3: 117,322,295 I638V probably benign Het
Ryr3 A G 2: 112,900,905 S687P possibly damaging Het
Skint5 T C 4: 113,940,784 T201A probably benign Het
Socs5 G T 17: 87,134,892 R420L probably damaging Het
Sos1 C T 17: 80,434,943 S385N possibly damaging Het
Tomm34 A T 2: 164,064,955 V106D probably damaging Het
Tubal3 T C 13: 3,932,750 S177P probably damaging Het
Wbp2nl G A 15: 82,306,173 A101T probably damaging Het
Other mutations in Rtl9
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02504:Rtl9 APN X 143102291 missense probably benign 0.38
IGL03227:Rtl9 APN X 143099828 missense probably benign 0.30
R0193:Rtl9 UTSW X 143100278 missense probably damaging 1.00
R0627:Rtl9 UTSW X 143101275 missense possibly damaging 0.94
R1828:Rtl9 UTSW X 143103015 missense possibly damaging 0.87
R1967:Rtl9 UTSW X 143103041 missense probably damaging 1.00
R2060:Rtl9 UTSW X 143102030 missense possibly damaging 0.52
Posted On2015-04-16