Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02433:Gm10073'

293198

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm10073

Ensembl Gene

ENSMUSG00000060019

Gene Name

predicted pseudogene 10073

Synonyms

Accession Numbers

Essential gene?

Not available question?

Stock #

IGL02433

Quality Score

Status

Chromosome

Chromosomal Location

107299641-107299982 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 107299951 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Cysteine at position 11 (Y11C)

Ref Sequence

ENSEMBL: ENSMUSP00000129695 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000073722]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000073722
AA Change: Y11C

PolyPhen 2 Score 0.047 (Sensitivity: 0.94; Specificity: 0.83)

SMART Domains

Protein: ENSMUSP00000129695
Gene: ENSMUSG00000060019
AA Change: Y11C

Domain	Start	End	E-Value	Type
Pfam:Ribosomal_60s	22	113	4.2e-29	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 22 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Bche	T	C	3: 73,609,262 (GRCm39)	T55A	probably benign	Het
Ccdc177	T	C	12: 80,804,372 (GRCm39)	D634G	unknown	Het
Cnot2	T	C	10: 116,328,241 (GRCm39)	T498A	possibly damaging	Het
Dock10	C	T	1: 80,507,905 (GRCm39)	V1669M	probably damaging	Het
Emilin2	T	C	17: 71,581,124 (GRCm39)	E534G	probably benign	Het
Flt4	G	A	11: 49,521,400 (GRCm39)	R440H	probably benign	Het
Ighv10-3	T	A	12: 114,487,514 (GRCm39)		probably benign	Het
Krt31	T	C	11: 99,939,221 (GRCm39)	Y232C	probably damaging	Het
Muc19	G	A	15: 91,756,694 (GRCm39)		noncoding transcript	Het
Myof	A	G	19: 37,960,641 (GRCm39)	S467P	probably benign	Het
Nup88	C	T	11: 70,860,714 (GRCm39)	V22I	probably benign	Het
Or4f14	G	T	2: 111,742,762 (GRCm39)	P171Q	probably damaging	Het
Or6c6c	A	T	10: 129,541,445 (GRCm39)	T233S	probably benign	Het
Or8h9	A	G	2: 86,789,392 (GRCm39)	S137P	possibly damaging	Het
Prag1	C	T	8: 36,606,722 (GRCm39)	P821L	probably damaging	Het
Pramel22	C	T	4: 143,382,007 (GRCm39)	G230S	possibly damaging	Het
Tap2	G	A	17: 34,424,393 (GRCm39)		probably benign	Het
Tmem68	A	T	4: 3,569,624 (GRCm39)	I22N	possibly damaging	Het
Usp17le	A	G	7: 104,418,408 (GRCm39)	W245R	probably benign	Het
Xpo5	G	T	17: 46,550,446 (GRCm39)	C976F	probably damaging	Het
Xrcc1	T	C	7: 24,264,979 (GRCm39)	S94P	possibly damaging	Het
Zfp524	T	A	7: 5,021,091 (GRCm39)	N206K	possibly damaging	Het

Other mutations in Gm10073

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01520:Gm10073	APN	8	107,299,901 (GRCm39)	missense	probably benign	0.13
IGL03282:Gm10073	APN	8	107,299,972 (GRCm39)	missense	probably benign	0.00
R1664:Gm10073	UTSW	8	107,299,864 (GRCm39)	missense	probably damaging	1.00

Posted On

2015-04-16