Incidental Mutation 'IGL02454:Tex55'
| ID |
293764 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Tex55
|
| Ensembl Gene |
ENSMUSG00000022798 |
| Gene Name |
testis expressed 55 |
| Synonyms |
4930435E12Rik |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.070)
|
| Stock # |
IGL02454
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
16 |
| Chromosomal Location |
38632568-38649111 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 38648309 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Serine
at position 267
(T267S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000113120
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000122078]
|
| AlphaFold |
A6X8Z9 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000122078
AA Change: T267S
PolyPhen 2
Score 0.023 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000113120
Gene: ENSMUSG00000022798
AA Change: T267S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
86 |
97 |
N/A |
INTRINSIC |
|
low complexity region
|
244 |
254 |
N/A |
INTRINSIC |
|
low complexity region
|
307 |
317 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000130241
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000148657
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000209595
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 35 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Amz2 |
T |
G |
11: 109,324,887 (GRCm39) |
|
probably benign |
Het |
| Atp13a5 |
A |
G |
16: 29,051,560 (GRCm39) |
F1104S |
probably benign |
Het |
| Cacna1c |
T |
C |
6: 118,579,141 (GRCm39) |
N1610S |
probably damaging |
Het |
| Ccnl1 |
A |
T |
3: 65,864,318 (GRCm39) |
D122E |
probably damaging |
Het |
| Crtc2 |
G |
A |
3: 90,166,474 (GRCm39) |
G65S |
probably benign |
Het |
| Dnah17 |
T |
C |
11: 117,971,593 (GRCm39) |
T2160A |
probably damaging |
Het |
| Fads3 |
T |
G |
19: 10,032,483 (GRCm39) |
L278R |
probably damaging |
Het |
| Foxp4 |
A |
T |
17: 48,186,507 (GRCm39) |
L424* |
probably null |
Het |
| Gm10392 |
A |
T |
11: 77,409,216 (GRCm39) |
E310V |
probably damaging |
Het |
| Gm11554 |
T |
A |
11: 99,694,815 (GRCm39) |
S133C |
unknown |
Het |
| Hacd2 |
T |
A |
16: 34,926,761 (GRCm39) |
F253L |
probably benign |
Het |
| Il3ra |
T |
C |
14: 14,351,113 (GRCm38) |
S212P |
probably benign |
Het |
| Mdn1 |
T |
C |
4: 32,694,674 (GRCm39) |
|
probably null |
Het |
| Mtfr1l |
A |
T |
4: 134,257,696 (GRCm39) |
L111H |
probably damaging |
Het |
| Mysm1 |
A |
G |
4: 94,858,741 (GRCm39) |
|
probably benign |
Het |
| Or10j2 |
C |
A |
1: 173,098,507 (GRCm39) |
S255Y |
probably damaging |
Het |
| Or52d1 |
T |
C |
7: 103,755,819 (GRCm39) |
V111A |
probably damaging |
Het |
| Plec |
A |
T |
15: 76,075,231 (GRCm39) |
F357I |
probably damaging |
Het |
| Polr3a |
C |
A |
14: 24,525,891 (GRCm39) |
V450L |
possibly damaging |
Het |
| Prkd1 |
T |
C |
12: 50,411,456 (GRCm39) |
K764R |
probably benign |
Het |
| Pxn |
C |
T |
5: 115,690,325 (GRCm39) |
P256S |
probably damaging |
Het |
| Rbm25 |
T |
A |
12: 83,707,096 (GRCm39) |
F247L |
probably benign |
Het |
| Rfx4 |
C |
T |
10: 84,675,970 (GRCm39) |
T62M |
possibly damaging |
Het |
| Rps4l-ps |
T |
C |
7: 114,526,499 (GRCm39) |
|
noncoding transcript |
Het |
| Scn11a |
A |
G |
9: 119,587,610 (GRCm39) |
I1378T |
probably benign |
Het |
| Siglecg |
T |
C |
7: 43,058,319 (GRCm39) |
S69P |
probably benign |
Het |
| Stox1 |
T |
C |
10: 62,503,605 (GRCm39) |
Y61C |
probably damaging |
Het |
| Tnks |
C |
T |
8: 35,298,882 (GRCm39) |
|
probably benign |
Het |
| Tpr |
A |
G |
1: 150,306,943 (GRCm39) |
S1587G |
probably benign |
Het |
| Trappc6b |
A |
G |
12: 59,090,433 (GRCm39) |
*97Q |
probably null |
Het |
| Usf3 |
T |
C |
16: 44,037,545 (GRCm39) |
V675A |
probably damaging |
Het |
| Wdr7 |
C |
T |
18: 63,929,299 (GRCm39) |
T1045M |
probably benign |
Het |
| Zc3h11a |
A |
T |
1: 133,552,254 (GRCm39) |
C618S |
probably benign |
Het |
| Zfp398 |
T |
C |
6: 47,817,301 (GRCm39) |
V47A |
possibly damaging |
Het |
| Zzz3 |
A |
G |
3: 152,134,211 (GRCm39) |
N423S |
probably benign |
Het |
|
| Other mutations in Tex55 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01979:Tex55
|
APN |
16 |
38,648,255 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
IGL01998:Tex55
|
APN |
16 |
38,648,586 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03216:Tex55
|
APN |
16 |
38,649,052 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
IGL03325:Tex55
|
APN |
16 |
38,648,355 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03397:Tex55
|
APN |
16 |
38,649,055 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7924_4930435E12Rik_239
|
UTSW |
16 |
38,632,826 (GRCm39) |
nonsense |
probably null |
|
|
BB001:Tex55
|
UTSW |
16 |
38,632,826 (GRCm39) |
nonsense |
probably null |
|
|
BB011:Tex55
|
UTSW |
16 |
38,632,826 (GRCm39) |
nonsense |
probably null |
|
|
R0242:Tex55
|
UTSW |
16 |
38,644,929 (GRCm39) |
splice site |
probably benign |
|
|
R0446:Tex55
|
UTSW |
16 |
38,649,064 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0607:Tex55
|
UTSW |
16 |
38,648,726 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1918:Tex55
|
UTSW |
16 |
38,648,450 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R1953:Tex55
|
UTSW |
16 |
38,648,275 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R3417:Tex55
|
UTSW |
16 |
38,649,102 (GRCm39) |
missense |
probably benign |
0.17 |
|
R4601:Tex55
|
UTSW |
16 |
38,648,380 (GRCm39) |
missense |
probably benign |
0.14 |
|
R4860:Tex55
|
UTSW |
16 |
38,648,507 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4860:Tex55
|
UTSW |
16 |
38,648,507 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5551:Tex55
|
UTSW |
16 |
38,648,336 (GRCm39) |
missense |
probably benign |
0.28 |
|
R7568:Tex55
|
UTSW |
16 |
38,648,809 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7623:Tex55
|
UTSW |
16 |
38,648,453 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7643:Tex55
|
UTSW |
16 |
38,648,225 (GRCm39) |
missense |
probably benign |
0.15 |
|
R7669:Tex55
|
UTSW |
16 |
38,648,453 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7670:Tex55
|
UTSW |
16 |
38,648,453 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7671:Tex55
|
UTSW |
16 |
38,648,453 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7924:Tex55
|
UTSW |
16 |
38,632,826 (GRCm39) |
nonsense |
probably null |
|
|
R9385:Tex55
|
UTSW |
16 |
38,648,407 (GRCm39) |
missense |
probably benign |
0.11 |
|
RF013:Tex55
|
UTSW |
16 |
38,648,363 (GRCm39) |
missense |
probably benign |
0.37 |
|
| Posted On |
2015-04-16 |
Incidental Mutation