Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02394:Tmem207'

293950

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Tmem207

Ensembl Gene

ENSMUSG00000091972

Gene Name

transmembrane protein 207

Synonyms

100043057, LOC224058

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.050) question?

Stock #

IGL02394

Quality Score

Status

Chromosome

Chromosomal Location

26322543-26345521 bp(-) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

A to G at 26335586 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000127563 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000165687]

AlphaFold

P86045

Predicted Effect

probably benign
Transcript: ENSMUST00000165687

SMART Domains

Protein: ENSMUSP00000127563
Gene: ENSMUSG00000091972

Domain	Start	End	E-Value	Type
Pfam:TMEM52	31	92	4.2e-10	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000231658

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 39 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Akt3	G	A	1: 176,886,985 (GRCm39)	T288M	probably damaging	Het
Baat	A	T	4: 49,489,812 (GRCm39)		probably benign	Het
Bclaf3	A	G	X: 158,338,485 (GRCm39)	Y444C	probably damaging	Het
Bcs1l	A	G	1: 74,629,459 (GRCm39)	T166A	probably damaging	Het
Cep135	C	T	5: 76,779,318 (GRCm39)	T776I	probably benign	Het
Clasrp	A	G	7: 19,337,179 (GRCm39)	L12P	probably damaging	Het
Csgalnact1	C	A	8: 68,854,144 (GRCm39)	G219V	probably damaging	Het
Cyp4f15	A	G	17: 32,911,609 (GRCm39)	I164V	possibly damaging	Het
Eps15	T	A	4: 109,170,162 (GRCm39)	L155M	probably damaging	Het
Fbxl20	G	A	11: 98,004,082 (GRCm39)	R69W	probably damaging	Het
Galnt9	A	G	5: 110,763,365 (GRCm39)	M457V	probably damaging	Het
Gemin2	T	A	12: 59,060,842 (GRCm39)		probably null	Het
Gm20521	T	A	14: 55,135,499 (GRCm39)	Y175N	probably damaging	Het
Gm3298	T	A	14: 5,018,778 (GRCm38)	C178S	probably benign	Het
Gpr37l1	T	C	1: 135,094,746 (GRCm39)	N166S	probably damaging	Het
Gpr45	A	G	1: 43,069,272 (GRCm39)		probably benign	Het
Gpr75	T	C	11: 30,842,190 (GRCm39)	I365T	possibly damaging	Het
Gsdmc2	T	C	15: 63,707,729 (GRCm39)	R22G	probably damaging	Het
Il23r	T	C	6: 67,443,256 (GRCm39)		probably benign	Het
Itgam	A	T	7: 127,684,114 (GRCm39)	T340S	probably benign	Het
Klk1b24	A	G	7: 43,841,294 (GRCm39)	D209G	possibly damaging	Het
Med13l	A	C	5: 118,886,898 (GRCm39)	T1600P	probably benign	Het
Muc16	G	T	9: 18,409,996 (GRCm39)	H137Q	probably damaging	Het
Nin	T	C	12: 70,090,805 (GRCm39)	E870G	probably damaging	Het
Or12k7	A	G	2: 36,958,497 (GRCm39)	Y60C	probably damaging	Het
Or5b120	A	G	19: 13,480,228 (GRCm39)	N174D	probably damaging	Het
Or6c215	A	T	10: 129,638,182 (GRCm39)	F71I	possibly damaging	Het
Pkhd1	T	C	1: 20,269,710 (GRCm39)	K3278R	possibly damaging	Het
Prlr	A	G	15: 10,328,664 (GRCm39)	N380D	probably benign	Het
Rpgr	A	C	X: 10,032,456 (GRCm39)	S582R	probably benign	Het
Rph3a	T	C	5: 121,084,411 (GRCm39)		probably null	Het
Setd5	A	G	6: 113,087,859 (GRCm39)	H140R	probably benign	Het
Stoml3	C	A	3: 53,405,540 (GRCm39)		probably benign	Het
Teddm1a	A	C	1: 153,767,545 (GRCm39)	D3A	probably benign	Het
Triml1	T	A	8: 43,591,629 (GRCm39)	Q243L	possibly damaging	Het
Usp5	G	A	6: 124,799,672 (GRCm39)	T274M	probably damaging	Het
Vav2	A	G	2: 27,187,671 (GRCm39)		probably benign	Het
Wdr5b	A	G	16: 35,862,633 (GRCm39)	N251D	probably damaging	Het
Wnk2	C	A	13: 49,235,375 (GRCm39)		probably null	Het

Other mutations in Tmem207

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01101:Tmem207	APN	16	26,336,627 (GRCm39)	nonsense	probably null
IGL02140:Tmem207	APN	16	26,335,490 (GRCm39)	missense	probably benign	0.01
IGL02249:Tmem207	APN	16	26,336,617 (GRCm39)	missense	possibly damaging	0.86
IGL03380:Tmem207	APN	16	26,345,407 (GRCm39)	missense	probably damaging	1.00
R0058:Tmem207	UTSW	16	26,343,579 (GRCm39)	splice site	probably benign
R0058:Tmem207	UTSW	16	26,343,579 (GRCm39)	splice site	probably benign
R1839:Tmem207	UTSW	16	26,343,571 (GRCm39)	missense	possibly damaging	0.80
R4943:Tmem207	UTSW	16	26,336,603 (GRCm39)	nonsense	probably null
R7348:Tmem207	UTSW	16	26,335,577 (GRCm39)	missense	possibly damaging	0.68
R7947:Tmem207	UTSW	16	26,335,495 (GRCm39)	missense	possibly damaging	0.82
R9358:Tmem207	UTSW	16	26,345,434 (GRCm39)	missense	probably benign	0.07
R9464:Tmem207	UTSW	16	26,345,413 (GRCm39)	missense
R9564:Tmem207	UTSW	16	26,335,499 (GRCm39)	nonsense	probably null

Posted On

2015-04-16