Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02447:Gm7361'

294011

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm7361

Ensembl Gene

ENSMUSG00000059645

Gene Name

predicted gene 7361

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.071) question?

Stock #

IGL02447

Quality Score

Status

Chromosome

Chromosomal Location

26462689-26469306 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 26462853 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Proline at position 32 (S32P)

Ref Sequence

ENSEMBL: ENSMUSP00000073781 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000074148]

AlphaFold

D3Z6R1

Predicted Effect

probably benign
Transcript: ENSMUST00000074148
AA Change: S32P

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000073781
Gene: ENSMUSG00000059645
AA Change: S32P

Domain	Start	End	E-Value	Type
Pfam:Takusan	50	134	2.1e-26	PFAM
low complexity region	154	168	N/A	INTRINSIC
low complexity region	235	259	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 49 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aadacl4fm4	T	A	4: 144,401,269 (GRCm39)	I72F	probably benign	Het
Abhd18	T	A	3: 40,888,208 (GRCm39)	F351I	probably benign	Het
Agfg1	T	A	1: 82,859,944 (GRCm39)		probably benign	Het
Antxr2	C	T	5: 98,178,267 (GRCm39)	V48I	possibly damaging	Het
Bcl9l	T	C	9: 44,418,631 (GRCm39)	M823T	probably benign	Het
Card11	G	A	5: 140,892,679 (GRCm39)	H129Y	possibly damaging	Het
Ccr1	A	T	9: 123,763,753 (GRCm39)	V259E	probably benign	Het
Cdk13	G	T	13: 17,947,001 (GRCm39)	P586T	probably benign	Het
Cep295	C	T	9: 15,243,807 (GRCm39)	V1502I	probably damaging	Het
Csnk1g3	T	C	18: 54,028,942 (GRCm39)	S32P	probably benign	Het
Dpysl4	G	A	7: 138,678,516 (GRCm39)	R492Q	probably damaging	Het
Duox2	A	G	2: 122,127,949 (GRCm39)	L78P	probably damaging	Het
Grip1	T	A	10: 119,855,976 (GRCm39)	V234E	probably damaging	Het
Herc1	A	T	9: 66,404,610 (GRCm39)	I4477L	possibly damaging	Het
Il18r1	G	A	1: 40,537,497 (GRCm39)		probably null	Het
Itpkb	A	G	1: 180,248,919 (GRCm39)		probably benign	Het
Jag2	T	C	12: 112,876,232 (GRCm39)	Y799C	probably damaging	Het
Jak2	A	G	19: 29,277,014 (GRCm39)	K857R	probably damaging	Het
Kbtbd12	A	T	6: 88,595,676 (GRCm39)	S51R	probably damaging	Het
Kcnc2	T	G	10: 112,291,851 (GRCm39)	D346E	probably damaging	Het
Kcnh1	T	A	1: 191,907,224 (GRCm39)	M92K	possibly damaging	Het
Kcnk1	A	G	8: 126,751,819 (GRCm39)	I142V	probably damaging	Het
Lsm11	T	C	11: 45,828,191 (GRCm39)	N196D	probably damaging	Het
Mpeg1	G	T	19: 12,440,156 (GRCm39)	C538F	probably damaging	Het
Nrap	G	A	19: 56,333,951 (GRCm39)	Q969*	probably null	Het
Nt5el	A	T	13: 105,236,967 (GRCm39)	S73C	probably damaging	Het
Nup205	T	C	6: 35,204,511 (GRCm39)		probably null	Het
Pdcd5	A	G	7: 35,342,110 (GRCm39)	V166A	possibly damaging	Het
Plcb2	A	T	2: 118,543,636 (GRCm39)	I745N	probably damaging	Het
Ptprt	T	C	2: 162,120,027 (GRCm39)	T147A	probably benign	Het
Rbp3	A	T	14: 33,676,460 (GRCm39)	D136V	probably damaging	Het
Ripor3	G	T	2: 167,834,750 (GRCm39)	T247N	probably damaging	Het
Sgcd	A	C	11: 46,870,082 (GRCm39)		probably benign	Het
Slc26a6	T	C	9: 108,734,251 (GRCm39)	Y211H	probably benign	Het
Slc37a3	T	A	6: 39,314,129 (GRCm39)	E494D	probably benign	Het
Smc5	T	C	19: 23,234,856 (GRCm39)	E326G	probably benign	Het
Tctn2	T	C	5: 124,753,316 (GRCm39)		noncoding transcript	Het
Tk2	T	A	8: 104,967,770 (GRCm39)	N93I	probably damaging	Het
Tmed6	A	G	8: 107,792,240 (GRCm39)	F2L	possibly damaging	Het
Tox3	A	G	8: 90,984,781 (GRCm39)		probably benign	Het
Tspan9	T	C	6: 127,941,401 (GRCm39)	Y237C	probably benign	Het
Ubqlnl	A	G	7: 103,797,856 (GRCm39)	L547P	probably damaging	Het
Uggt1	T	C	1: 36,189,223 (GRCm39)	D1421G	probably damaging	Het
Unc80	T	A	1: 66,542,703 (GRCm39)	I319K	possibly damaging	Het
Vac14	A	G	8: 111,380,260 (GRCm39)	D441G	probably benign	Het
Vamp8	C	T	6: 72,365,316 (GRCm39)	V5M	probably damaging	Het
Yeats2	T	A	16: 20,012,429 (GRCm39)	H560Q	probably benign	Het
Zfp13	C	T	17: 23,795,072 (GRCm39)	A493T	probably benign	Het
Zfp773	G	T	7: 7,139,655 (GRCm39)		probably benign	Het

Other mutations in Gm7361

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02550:Gm7361	APN	5	26,466,120 (GRCm39)	missense	possibly damaging	0.79
R0011:Gm7361	UTSW	5	26,463,876 (GRCm39)	splice site	probably benign
R0959:Gm7361	UTSW	5	26,467,051 (GRCm39)	missense	possibly damaging	0.86
R1246:Gm7361	UTSW	5	26,466,225 (GRCm39)	nonsense	probably null
R1580:Gm7361	UTSW	5	26,462,768 (GRCm39)	missense	probably damaging	0.97
R1654:Gm7361	UTSW	5	26,466,097 (GRCm39)	missense	probably damaging	0.99
R2065:Gm7361	UTSW	5	26,467,149 (GRCm39)	missense	probably damaging	1.00
R4864:Gm7361	UTSW	5	26,467,008 (GRCm39)	critical splice acceptor site	probably null
R5386:Gm7361	UTSW	5	26,463,903 (GRCm39)	missense	probably benign
R6282:Gm7361	UTSW	5	26,465,411 (GRCm39)	missense	probably benign	0.13
R6391:Gm7361	UTSW	5	26,463,960 (GRCm39)	missense	probably benign	0.37
R6769:Gm7361	UTSW	5	26,462,767 (GRCm39)	nonsense	probably null
R7205:Gm7361	UTSW	5	26,466,116 (GRCm39)	missense	probably damaging	0.99
R7497:Gm7361	UTSW	5	26,466,188 (GRCm39)	missense	probably benign
R7498:Gm7361	UTSW	5	26,466,188 (GRCm39)	missense	probably benign
R7499:Gm7361	UTSW	5	26,466,188 (GRCm39)	missense	probably benign
R8086:Gm7361	UTSW	5	26,465,446 (GRCm39)	missense	probably damaging	0.99
R8325:Gm7361	UTSW	5	26,467,154 (GRCm39)	missense	probably damaging	0.98
R8349:Gm7361	UTSW	5	26,465,387 (GRCm39)	missense	possibly damaging	0.95
R8449:Gm7361	UTSW	5	26,465,387 (GRCm39)	missense	possibly damaging	0.95
Z1177:Gm7361	UTSW	5	26,466,186 (GRCm39)	missense	probably benign	0.01

Posted On

2015-04-16