Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02447:Zfp773'

294056

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Zfp773

Ensembl Gene

ENSMUSG00000063535

Gene Name

zinc finger protein 773

Synonyms

2810409K11Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.055) question?

Stock #

IGL02447

Quality Score

Status

Chromosome

Chromosomal Location

7133677-7139754 bp(-) (GRCm39)

Type of Mutation

utr 5 prime

DNA Base Change (assembly)

G to T at 7139655 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000147639 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000032622] [ENSMUST00000211240]

AlphaFold

Q9CZ29

Predicted Effect

probably benign
Transcript: ENSMUST00000032622

SMART Domains

Protein: ENSMUSP00000032622
Gene: ENSMUSG00000063535

Domain	Start	End	E-Value	Type
KRAB	75	134	6.82e-8	SMART
ZnF_C2H2	241	263	1.31e0	SMART
ZnF_C2H2	269	291	1.5e-4	SMART
ZnF_C2H2	297	319	4.17e-3	SMART
ZnF_C2H2	325	347	2.05e-2	SMART
ZnF_C2H2	353	375	2.24e-3	SMART
ZnF_C2H2	381	403	8.81e-2	SMART
ZnF_C2H2	409	431	7.26e-3	SMART
ZnF_C2H2	437	459	7.26e-3	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000211240

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 49 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aadacl4fm4	T	A	4: 144,401,269 (GRCm39)	I72F	probably benign	Het
Abhd18	T	A	3: 40,888,208 (GRCm39)	F351I	probably benign	Het
Agfg1	T	A	1: 82,859,944 (GRCm39)		probably benign	Het
Antxr2	C	T	5: 98,178,267 (GRCm39)	V48I	possibly damaging	Het
Bcl9l	T	C	9: 44,418,631 (GRCm39)	M823T	probably benign	Het
Card11	G	A	5: 140,892,679 (GRCm39)	H129Y	possibly damaging	Het
Ccr1	A	T	9: 123,763,753 (GRCm39)	V259E	probably benign	Het
Cdk13	G	T	13: 17,947,001 (GRCm39)	P586T	probably benign	Het
Cep295	C	T	9: 15,243,807 (GRCm39)	V1502I	probably damaging	Het
Csnk1g3	T	C	18: 54,028,942 (GRCm39)	S32P	probably benign	Het
Dpysl4	G	A	7: 138,678,516 (GRCm39)	R492Q	probably damaging	Het
Duox2	A	G	2: 122,127,949 (GRCm39)	L78P	probably damaging	Het
Gm7361	T	C	5: 26,462,853 (GRCm39)	S32P	probably benign	Het
Grip1	T	A	10: 119,855,976 (GRCm39)	V234E	probably damaging	Het
Herc1	A	T	9: 66,404,610 (GRCm39)	I4477L	possibly damaging	Het
Il18r1	G	A	1: 40,537,497 (GRCm39)		probably null	Het
Itpkb	A	G	1: 180,248,919 (GRCm39)		probably benign	Het
Jag2	T	C	12: 112,876,232 (GRCm39)	Y799C	probably damaging	Het
Jak2	A	G	19: 29,277,014 (GRCm39)	K857R	probably damaging	Het
Kbtbd12	A	T	6: 88,595,676 (GRCm39)	S51R	probably damaging	Het
Kcnc2	T	G	10: 112,291,851 (GRCm39)	D346E	probably damaging	Het
Kcnh1	T	A	1: 191,907,224 (GRCm39)	M92K	possibly damaging	Het
Kcnk1	A	G	8: 126,751,819 (GRCm39)	I142V	probably damaging	Het
Lsm11	T	C	11: 45,828,191 (GRCm39)	N196D	probably damaging	Het
Mpeg1	G	T	19: 12,440,156 (GRCm39)	C538F	probably damaging	Het
Nrap	G	A	19: 56,333,951 (GRCm39)	Q969*	probably null	Het
Nt5el	A	T	13: 105,236,967 (GRCm39)	S73C	probably damaging	Het
Nup205	T	C	6: 35,204,511 (GRCm39)		probably null	Het
Pdcd5	A	G	7: 35,342,110 (GRCm39)	V166A	possibly damaging	Het
Plcb2	A	T	2: 118,543,636 (GRCm39)	I745N	probably damaging	Het
Ptprt	T	C	2: 162,120,027 (GRCm39)	T147A	probably benign	Het
Rbp3	A	T	14: 33,676,460 (GRCm39)	D136V	probably damaging	Het
Ripor3	G	T	2: 167,834,750 (GRCm39)	T247N	probably damaging	Het
Sgcd	A	C	11: 46,870,082 (GRCm39)		probably benign	Het
Slc26a6	T	C	9: 108,734,251 (GRCm39)	Y211H	probably benign	Het
Slc37a3	T	A	6: 39,314,129 (GRCm39)	E494D	probably benign	Het
Smc5	T	C	19: 23,234,856 (GRCm39)	E326G	probably benign	Het
Tctn2	T	C	5: 124,753,316 (GRCm39)		noncoding transcript	Het
Tk2	T	A	8: 104,967,770 (GRCm39)	N93I	probably damaging	Het
Tmed6	A	G	8: 107,792,240 (GRCm39)	F2L	possibly damaging	Het
Tox3	A	G	8: 90,984,781 (GRCm39)		probably benign	Het
Tspan9	T	C	6: 127,941,401 (GRCm39)	Y237C	probably benign	Het
Ubqlnl	A	G	7: 103,797,856 (GRCm39)	L547P	probably damaging	Het
Uggt1	T	C	1: 36,189,223 (GRCm39)	D1421G	probably damaging	Het
Unc80	T	A	1: 66,542,703 (GRCm39)	I319K	possibly damaging	Het
Vac14	A	G	8: 111,380,260 (GRCm39)	D441G	probably benign	Het
Vamp8	C	T	6: 72,365,316 (GRCm39)	V5M	probably damaging	Het
Yeats2	T	A	16: 20,012,429 (GRCm39)	H560Q	probably benign	Het
Zfp13	C	T	17: 23,795,072 (GRCm39)	A493T	probably benign	Het

Other mutations in Zfp773

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00764:Zfp773	APN	7	7,135,683 (GRCm39)	missense	probably damaging	1.00
IGL00780:Zfp773	APN	7	7,136,113 (GRCm39)	missense	probably benign	0.00
IGL01348:Zfp773	APN	7	7,138,314 (GRCm39)	missense	possibly damaging	0.93
IGL02224:Zfp773	APN	7	7,135,975 (GRCm39)	missense	probably benign	0.00
IGL02869:Zfp773	APN	7	7,137,232 (GRCm39)	missense	probably benign	0.22
R0505:Zfp773	UTSW	7	7,136,023 (GRCm39)	missense	probably benign	0.03
R0585:Zfp773	UTSW	7	7,135,574 (GRCm39)	missense	probably benign	0.21
R0804:Zfp773	UTSW	7	7,136,092 (GRCm39)	intron	probably benign
R0846:Zfp773	UTSW	7	7,135,691 (GRCm39)	missense	probably damaging	1.00
R1179:Zfp773	UTSW	7	7,136,092 (GRCm39)	intron	probably benign
R2847:Zfp773	UTSW	7	7,136,092 (GRCm39)	intron	probably benign
R3841:Zfp773	UTSW	7	7,135,390 (GRCm39)	missense	possibly damaging	0.92
R4116:Zfp773	UTSW	7	7,136,092 (GRCm39)	intron	probably benign
R4638:Zfp773	UTSW	7	7,138,335 (GRCm39)	missense	probably damaging	1.00
R5126:Zfp773	UTSW	7	7,139,623 (GRCm39)	missense	unknown
R6142:Zfp773	UTSW	7	7,135,481 (GRCm39)	missense	probably benign	0.00
R7072:Zfp773	UTSW	7	7,135,874 (GRCm39)	missense	probably benign	0.15
R7232:Zfp773	UTSW	7	7,135,984 (GRCm39)	missense	probably benign	0.14
R7748:Zfp773	UTSW	7	7,135,907 (GRCm39)	missense	probably benign	0.04
R7888:Zfp773	UTSW	7	7,135,978 (GRCm39)	missense	probably benign	0.00
R8681:Zfp773	UTSW	7	7,139,482 (GRCm39)	missense	possibly damaging	0.70
R8784:Zfp773	UTSW	7	7,135,570 (GRCm39)	missense	probably benign	0.19
R8946:Zfp773	UTSW	7	7,135,469 (GRCm39)	missense	possibly damaging	0.82
R9056:Zfp773	UTSW	7	7,135,989 (GRCm39)	missense	probably damaging	0.99
R9154:Zfp773	UTSW	7	7,138,302 (GRCm39)	missense	probably damaging	0.98
R9295:Zfp773	UTSW	7	7,135,694 (GRCm39)	missense	probably benign	0.06
RF007:Zfp773	UTSW	7	7,135,689 (GRCm39)	nonsense	probably null

Posted On

2015-04-16