Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02471:Snx24'

294751

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Snx24

Ensembl Gene

ENSMUSG00000024535

Gene Name

sorting nexing 24

Synonyms

2810011K15Rik, 5730433I16Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.087) question?

Stock #

IGL02471

Quality Score

Status

Chromosome

Chromosomal Location

53378734-53523992 bp(+) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

C to T at 53518241 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000131423 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000025417] [ENSMUST00000165032]

AlphaFold

Q9CRB0

Predicted Effect

probably benign
Transcript: ENSMUST00000025417

SMART Domains

Protein: ENSMUSP00000025417
Gene: ENSMUSG00000024535

Domain	Start	End	E-Value	Type
PX	1	103	4.19e-10	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000165032

SMART Domains

Protein: ENSMUSP00000131423
Gene: ENSMUSG00000024535

Domain	Start	End	E-Value	Type
PX	1	103	4.19e-10	SMART

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 45 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca12	G	T	1: 71,297,357 (GRCm39)	H2378N	probably benign	Het
Btaf1	C	A	19: 36,977,592 (GRCm39)	A1470E	probably damaging	Het
Ccdc110	A	G	8: 46,394,793 (GRCm39)	D228G	probably benign	Het
Cdc45	C	T	16: 18,617,479 (GRCm39)	M200I	probably benign	Het
Cldn18	T	C	9: 99,578,128 (GRCm39)	D205G	probably benign	Het
Clip2	T	C	5: 134,546,876 (GRCm39)	T231A	probably benign	Het
Cltc	A	G	11: 86,608,860 (GRCm39)	V723A	probably damaging	Het
Cpa3	C	T	3: 20,282,971 (GRCm39)		probably null	Het
Cyfip2	T	G	11: 46,091,630 (GRCm39)	T1097P	possibly damaging	Het
Dnah9	T	A	11: 65,838,444 (GRCm39)	R667*	probably null	Het
Dock10	T	C	1: 80,493,339 (GRCm39)	E1878G	probably damaging	Het
Ermap	G	A	4: 119,037,160 (GRCm39)	H353Y	probably damaging	Het
Etfa	A	T	9: 55,393,984 (GRCm39)		probably null	Het
F5	C	T	1: 164,001,860 (GRCm39)	P188S	probably damaging	Het
Foxq1	G	A	13: 31,743,326 (GRCm39)	E143K	possibly damaging	Het
Gsr	C	T	8: 34,172,612 (GRCm39)		probably benign	Het
Hebp1	T	A	6: 135,132,274 (GRCm39)	Y31F	probably benign	Het
Ighv1-14	T	C	12: 114,610,457 (GRCm39)		noncoding transcript	Het
Lamb1	T	A	12: 31,370,907 (GRCm39)	D1319E	probably damaging	Het
Lrp5	A	T	19: 3,652,408 (GRCm39)	V1154E	probably benign	Het
Manba	G	A	3: 135,212,769 (GRCm39)		probably benign	Het
Mknk2	A	T	10: 80,503,955 (GRCm39)	F319I	probably damaging	Het
Mup6	A	T	4: 60,003,971 (GRCm39)		probably benign	Het
Nalcn	T	C	14: 123,560,726 (GRCm39)	T784A	probably benign	Het
Nt5dc1	T	C	10: 34,279,721 (GRCm39)	E107G	probably benign	Het
Or11h6	A	T	14: 50,880,214 (GRCm39)	I159F	probably benign	Het
Or56b34	T	A	7: 104,938,252 (GRCm39)	F317L	probably benign	Het
Or9q2	G	A	19: 13,772,589 (GRCm39)	P129S	probably damaging	Het
Phldb1	T	C	9: 44,622,530 (GRCm39)	E41G	probably damaging	Het
Ptk2	T	C	15: 73,170,036 (GRCm39)	D309G	probably benign	Het
Rab11fip5	A	G	6: 85,325,207 (GRCm39)	S367P	probably damaging	Het
Rb1cc1	T	A	1: 6,310,275 (GRCm39)	N224K	probably benign	Het
Rchy1	A	T	5: 92,105,405 (GRCm39)	C65*	probably null	Het
Rgs18	T	C	1: 144,650,359 (GRCm39)	D56G	probably benign	Het
Rtraf	A	C	14: 19,862,296 (GRCm39)	L197R	probably damaging	Het
Slc44a5	G	T	3: 153,962,213 (GRCm39)	W382L	probably damaging	Het
Sphkap	T	C	1: 83,253,897 (GRCm39)	D1284G	probably damaging	Het
Tmem54	A	G	4: 129,002,111 (GRCm39)	M53V	probably benign	Het
Trip6	G	A	5: 137,308,618 (GRCm39)	P414S	probably benign	Het
Vmn1r38	A	G	6: 66,753,751 (GRCm39)	Y122H	probably benign	Het
Wapl	T	A	14: 34,413,877 (GRCm39)	N246K	possibly damaging	Het
Zfp12	G	A	5: 143,230,551 (GRCm39)	G293R	probably damaging	Het
Zfp13	C	T	17: 23,795,072 (GRCm39)	A493T	probably benign	Het
Zfp446	T	G	7: 12,716,181 (GRCm39)	V209G	probably benign	Het
Zfp518a	G	A	19: 40,903,061 (GRCm39)	G997R	probably damaging	Het

Other mutations in Snx24

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00731:Snx24	APN	18	53,517,681 (GRCm39)	splice site	probably benign
IGL02704:Snx24	APN	18	53,460,509 (GRCm39)	missense	probably benign
R1645:Snx24	UTSW	18	53,522,634 (GRCm39)	missense	probably benign
R4900:Snx24	UTSW	18	53,518,295 (GRCm39)	nonsense	probably null
R5307:Snx24	UTSW	18	53,473,283 (GRCm39)	nonsense	probably null
R7039:Snx24	UTSW	18	53,473,307 (GRCm39)	critical splice donor site	probably null
R7299:Snx24	UTSW	18	53,473,244 (GRCm39)	missense	probably damaging	1.00
R7301:Snx24	UTSW	18	53,473,244 (GRCm39)	missense	probably damaging	1.00
R7805:Snx24	UTSW	18	53,522,623 (GRCm39)	missense	probably benign	0.22

Posted On

2015-04-16