Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02472:Dock2'

294786

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Dock2

Ensembl Gene

ENSMUSG00000020143

Gene Name

dedicator of cyto-kinesis 2

Synonyms

CED-5, MBC, Hch

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL02472

Quality Score

Status

Chromosome

Chromosomal Location

34226815-34783892 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 34249801 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Glutamic Acid to Aspartic acid at position 1416 (E1416D)

Ref Sequence

ENSEMBL: ENSMUSP00000090884 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000093193]

AlphaFold

Q8C3J5

Predicted Effect

probably benign
Transcript: ENSMUST00000093193
AA Change: E1416D

PolyPhen 2 Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)

SMART Domains

Protein: ENSMUSP00000090884
Gene: ENSMUSG00000020143
AA Change: E1416D

Domain	Start	End	E-Value	Type
SH3	11	68	1.22e-11	SMART
Pfam:DOCK_N	71	414	2e-113	PFAM
Pfam:DOCK-C2	419	616	1e-60	PFAM
Pfam:DHR-2	1114	1614	6.3e-96	PFAM
low complexity region	1691	1706	N/A	INTRINSIC
low complexity region	1793	1800	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP. [provided by RefSeq, Oct 2016]
PHENOTYPE: Homozygous mutants are defective in the migration of T and B lympohcytes in response to chemokines, and thus display immune defects such as lymphocytopenia, atrophy of lymphoid follicles and loss of marginal-zone B cells. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 45 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1110038F14Rik	A	G	15: 76,950,378 (GRCm38)	N158S	probably damaging	Het
Ankrd17	A	C	5: 90,264,151 (GRCm38)	L1285V	probably damaging	Het
Atp8b2	G	A	3: 89,954,239 (GRCm38)	T267I	probably damaging	Het
Becn1	C	T	11: 101,291,398 (GRCm38)	G115D	probably benign	Het
Cdc45	C	T	16: 18,798,729 (GRCm38)	M200I	probably benign	Het
Chd6	A	C	2: 160,984,452 (GRCm38)		probably benign	Het
Col22a1	A	G	15: 71,827,753 (GRCm38)		probably benign	Het
Csgalnact1	C	A	8: 68,401,492 (GRCm38)	G219V	probably damaging	Het
Dnm2	A	G	9: 21,485,708 (GRCm38)	I494V	possibly damaging	Het
Eif2ak1	A	G	5: 143,884,883 (GRCm38)	H339R	probably benign	Het
Espnl	C	T	1: 91,340,534 (GRCm38)	P294L	probably benign	Het
Ftmt	T	A	18: 52,331,840 (GRCm38)	I76N	possibly damaging	Het
Gorasp2	T	G	2: 70,676,459 (GRCm38)		probably benign	Het
Hadhb	T	A	5: 30,184,063 (GRCm38)	M468K	possibly damaging	Het
Hfm1	A	G	5: 106,873,928 (GRCm38)		probably benign	Het
Inpp5j	T	C	11: 3,495,338 (GRCm38)		probably benign	Het
Ipo7	T	A	7: 110,040,853 (GRCm38)	F288I	probably damaging	Het
Kcnv1	T	A	15: 45,109,123 (GRCm38)	K455*	probably null	Het
Kdm5a	A	G	6: 120,406,730 (GRCm38)		probably benign	Het
Kmt2d	G	A	15: 98,850,077 (GRCm38)	S3122F	probably benign	Het
Kndc1	A	G	7: 139,910,901 (GRCm38)	I440V	probably benign	Het
Mib2	T	A	4: 155,656,746 (GRCm38)	I545F	probably damaging	Het
Nav2	C	T	7: 49,546,041 (GRCm38)	P1055L	probably damaging	Het
Or4c10b	T	A	2: 89,881,411 (GRCm38)	I195N	probably benign	Het
Or5v1b	C	A	17: 37,530,749 (GRCm38)	F257L	probably damaging	Het
Plch1	A	T	3: 63,701,849 (GRCm38)	L65Q	probably damaging	Het
Polr1g	T	C	7: 19,359,105 (GRCm38)	D50G	probably damaging	Het
Ppp3ca	A	G	3: 136,921,862 (GRCm38)	I396V	possibly damaging	Het
Ryr1	A	T	7: 29,040,844 (GRCm38)	N3917K	probably damaging	Het
Scn7a	T	C	2: 66,752,314 (GRCm38)	T80A	probably damaging	Het
Sema3f	C	T	9: 107,687,736 (GRCm38)	E307K	probably damaging	Het
Serpinb9b	A	T	13: 33,039,970 (GRCm38)		probably benign	Het
Siglec15	T	A	18: 78,043,617 (GRCm38)	K342N	possibly damaging	Het
Slc2a12	T	C	10: 22,665,155 (GRCm38)	F303S	probably damaging	Het
Slc9c1	T	C	16: 45,580,142 (GRCm38)	V705A	probably benign	Het
Tenm4	T	C	7: 96,774,176 (GRCm38)		probably benign	Het
Tm6sf1	A	T	7: 81,875,824 (GRCm38)		probably benign	Het
Tmem245	T	C	4: 56,899,119 (GRCm38)	Y269C	probably damaging	Het
Txndc2	A	G	17: 65,637,976 (GRCm38)	I402T	possibly damaging	Het
Ube4b	A	G	4: 149,387,079 (GRCm38)		probably null	Het
Usp28	T	A	9: 49,037,769 (GRCm38)	Y863N	possibly damaging	Het
Vmn2r69	T	C	7: 85,409,752 (GRCm38)	I534V	probably benign	Het
Wdr89	A	T	12: 75,632,969 (GRCm38)	D170E	probably damaging	Het
Zfp280d	C	A	9: 72,301,711 (GRCm38)	N74K	probably damaging	Het
Zfp518a	G	A	19: 40,914,617 (GRCm38)	G997R	probably damaging	Het

Other mutations in Dock2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00334:Dock2	APN	11	34,704,661 (GRCm38)	missense	probably damaging	1.00
IGL00469:Dock2	APN	11	34,229,603 (GRCm38)	splice site	probably benign
IGL01061:Dock2	APN	11	34,705,826 (GRCm38)	missense	probably damaging	1.00
IGL01319:Dock2	APN	11	34,698,790 (GRCm38)	missense	possibly damaging	0.61
IGL01451:Dock2	APN	11	34,310,390 (GRCm38)	missense	probably damaging	1.00
IGL01490:Dock2	APN	11	34,705,781 (GRCm38)	missense	probably damaging	0.97
IGL01601:Dock2	APN	11	34,239,528 (GRCm38)	critical splice donor site	probably null
IGL01800:Dock2	APN	11	34,756,273 (GRCm38)	missense	probably damaging	1.00
IGL01804:Dock2	APN	11	34,262,433 (GRCm38)	missense	probably benign	0.01
IGL01823:Dock2	APN	11	34,262,391 (GRCm38)	missense	probably damaging	1.00
IGL01829:Dock2	APN	11	34,705,841 (GRCm38)	missense	probably damaging	0.98
IGL01830:Dock2	APN	11	34,691,917 (GRCm38)	nonsense	probably null
IGL01835:Dock2	APN	11	34,310,435 (GRCm38)	missense	possibly damaging	0.51
IGL01845:Dock2	APN	11	34,708,865 (GRCm38)	missense	probably benign	0.02
IGL01953:Dock2	APN	11	34,732,356 (GRCm38)	missense	probably benign	0.28
IGL01989:Dock2	APN	11	34,268,053 (GRCm38)	missense	probably benign
IGL02081:Dock2	APN	11	34,254,355 (GRCm38)	missense	probably benign
IGL02105:Dock2	APN	11	34,714,525 (GRCm38)	missense	probably damaging	1.00
IGL02153:Dock2	APN	11	34,230,670 (GRCm38)	missense	probably benign	0.01
IGL02170:Dock2	APN	11	34,267,949 (GRCm38)	missense	probably damaging	1.00
IGL02344:Dock2	APN	11	34,731,510 (GRCm38)	missense	probably damaging	0.98
IGL02389:Dock2	APN	11	34,698,740 (GRCm38)	splice site	probably benign
IGL02409:Dock2	APN	11	34,501,204 (GRCm38)	missense	probably benign	0.00
IGL02625:Dock2	APN	11	34,501,168 (GRCm38)	critical splice donor site	probably null
IGL02929:Dock2	APN	11	34,268,048 (GRCm38)	missense	probably damaging	1.00
IGL02951:Dock2	APN	11	34,310,448 (GRCm38)	unclassified	probably benign
IGL02999:Dock2	APN	11	34,692,259 (GRCm38)	missense	probably damaging	0.99
IGL03165:Dock2	APN	11	34,687,533 (GRCm38)	missense	probably damaging	0.99
Arches	UTSW	11	34,689,760 (GRCm38)	missense	probably damaging	1.00
capitol_reef	UTSW	11	34,294,170 (GRCm38)	critical splice acceptor site	probably null
Croesus	UTSW	11	34,721,027 (GRCm38)	missense	probably damaging	1.00
denali	UTSW	11	34,229,472 (GRCm38)	critical splice donor site	probably null
dew	UTSW	11	34,248,636 (GRCm38)	nonsense	probably null
Dinghy	UTSW	11	34,262,460 (GRCm38)	missense	possibly damaging	0.70
Dry	UTSW	11	34,231,652 (GRCm38)	missense	possibly damaging	0.79
frazz	UTSW	11	34,248,572 (GRCm38)	critical splice donor site	probably benign
frizz	UTSW	11	34,258,184 (GRCm38)	splice site	probably benign
gildenstern	UTSW	11	34,732,339 (GRCm38)	critical splice donor site	probably null
godsgrace	UTSW	11	34,695,453 (GRCm38)	missense	probably damaging	1.00
Harborside	UTSW	11	34,262,445 (GRCm38)	missense	probably benign
Landing	UTSW	11	34,714,501 (GRCm38)	missense	possibly damaging	0.83
latest	UTSW	11	34,756,222 (GRCm38)	missense	probably damaging	1.00
Launch	UTSW	11	34,256,562 (GRCm38)	missense	probably damaging	1.00
liaoning	UTSW	11	34,708,793 (GRCm38)	missense	probably damaging	1.00
lucre	UTSW	11	34,704,609 (GRCm38)	frame shift	probably null
midas	UTSW	11	34,294,323 (GRCm38)	missense	probably damaging	0.99
muelle	UTSW	11	34,687,538 (GRCm38)	missense	probably damaging	1.00
narrowest	UTSW	11	34,282,652 (GRCm38)	missense	probably damaging	0.98
pier	UTSW	11	34,689,766 (GRCm38)	missense	probably damaging	1.00
Plank	UTSW	11	34,783,795 (GRCm38)	missense	possibly damaging	0.51
resplendent	UTSW	11	34,727,460 (GRCm38)	nonsense	probably null
riches	UTSW	11	34,688,452 (GRCm38)	critical splice donor site	probably null
skiff	UTSW	11	34,262,388 (GRCm38)	missense	probably null	0.80
Slip	UTSW	11	34,294,286 (GRCm38)	missense	probably benign	0.25
toothskin	UTSW	11	34,464,922 (GRCm38)	missense	probably damaging	1.00
Touch	UTSW	11	34,273,750 (GRCm38)	missense	possibly damaging	0.95
wassup	UTSW	11	34,503,413 (GRCm38)	missense	probably damaging	1.00
Wharf	UTSW	11	34,732,371 (GRCm38)	missense	possibly damaging	0.81
BB009:Dock2	UTSW	11	34,267,998 (GRCm38)	missense	probably benign	0.00
BB019:Dock2	UTSW	11	34,267,998 (GRCm38)	missense	probably benign	0.00
IGL03052:Dock2	UTSW	11	34,232,853 (GRCm38)	missense	probably benign	0.01
PIT4377001:Dock2	UTSW	11	34,721,008 (GRCm38)	missense	probably benign	0.02
R0006:Dock2	UTSW	11	34,312,453 (GRCm38)	unclassified	probably benign
R0012:Dock2	UTSW	11	34,783,795 (GRCm38)	missense	possibly damaging	0.51
R0063:Dock2	UTSW	11	34,756,284 (GRCm38)	critical splice acceptor site	probably null
R0063:Dock2	UTSW	11	34,756,284 (GRCm38)	critical splice acceptor site	probably null
R0116:Dock2	UTSW	11	34,688,565 (GRCm38)	intron	probably benign
R0149:Dock2	UTSW	11	34,438,327 (GRCm38)	missense	probably damaging	1.00
R0361:Dock2	UTSW	11	34,438,327 (GRCm38)	missense	probably damaging	1.00
R0462:Dock2	UTSW	11	34,268,052 (GRCm38)	missense	possibly damaging	0.74
R0471:Dock2	UTSW	11	34,688,553 (GRCm38)	missense	probably benign	0.30
R0538:Dock2	UTSW	11	34,704,718 (GRCm38)	splice site	probably benign
R0543:Dock2	UTSW	11	34,294,325 (GRCm38)	missense	probably damaging	1.00
R0660:Dock2	UTSW	11	34,248,621 (GRCm38)	missense	probably damaging	1.00
R0676:Dock2	UTSW	11	34,695,236 (GRCm38)	missense	probably damaging	0.99
R0722:Dock2	UTSW	11	34,464,970 (GRCm38)	splice site	probably benign
R0801:Dock2	UTSW	11	34,708,793 (GRCm38)	missense	probably damaging	1.00
R1110:Dock2	UTSW	11	34,256,535 (GRCm38)	missense	possibly damaging	0.78
R1171:Dock2	UTSW	11	34,695,241 (GRCm38)	missense	probably damaging	1.00
R1387:Dock2	UTSW	11	34,273,309 (GRCm38)	splice site	probably benign
R1445:Dock2	UTSW	11	34,239,705 (GRCm38)	missense	probably benign
R1494:Dock2	UTSW	11	34,282,761 (GRCm38)	nonsense	probably null
R1589:Dock2	UTSW	11	34,706,461 (GRCm38)	missense	probably damaging	0.99
R1597:Dock2	UTSW	11	34,704,647 (GRCm38)	missense	probably benign	0.00
R1629:Dock2	UTSW	11	34,262,480 (GRCm38)	splice site	probably null
R1749:Dock2	UTSW	11	34,232,767 (GRCm38)	critical splice donor site	probably null
R1888:Dock2	UTSW	11	34,707,342 (GRCm38)	missense	probably damaging	1.00
R1888:Dock2	UTSW	11	34,707,342 (GRCm38)	missense	probably damaging	1.00
R1899:Dock2	UTSW	11	34,294,286 (GRCm38)	missense	probably benign	0.25
R1924:Dock2	UTSW	11	34,464,934 (GRCm38)	missense	possibly damaging	0.69
R2031:Dock2	UTSW	11	34,727,470 (GRCm38)	splice site	probably benign
R2045:Dock2	UTSW	11	34,294,106 (GRCm38)	splice site	probably null
R2098:Dock2	UTSW	11	34,719,005 (GRCm38)	missense	probably damaging	0.99
R2098:Dock2	UTSW	11	34,266,279 (GRCm38)	missense	probably benign	0.16
R2129:Dock2	UTSW	11	34,727,415 (GRCm38)	missense	probably damaging	1.00
R2147:Dock2	UTSW	11	34,229,472 (GRCm38)	critical splice donor site	probably null
R2149:Dock2	UTSW	11	34,229,472 (GRCm38)	critical splice donor site	probably null
R2150:Dock2	UTSW	11	34,229,472 (GRCm38)	critical splice donor site	probably null
R2176:Dock2	UTSW	11	34,695,217 (GRCm38)	missense	probably benign	0.00
R2230:Dock2	UTSW	11	34,294,323 (GRCm38)	missense	probably damaging	0.99
R2508:Dock2	UTSW	11	34,312,485 (GRCm38)	missense	probably benign	0.04
R2875:Dock2	UTSW	11	34,718,885 (GRCm38)	missense	probably damaging	1.00
R2885:Dock2	UTSW	11	34,689,766 (GRCm38)	missense	probably damaging	1.00
R2910:Dock2	UTSW	11	34,232,910 (GRCm38)	splice site	probably benign
R3081:Dock2	UTSW	11	34,231,610 (GRCm38)	missense	probably benign
R3418:Dock2	UTSW	11	34,689,760 (GRCm38)	missense	probably damaging	1.00
R3552:Dock2	UTSW	11	34,720,960 (GRCm38)	missense	probably benign	0.22
R3731:Dock2	UTSW	11	34,708,895 (GRCm38)	missense	probably damaging	1.00
R3846:Dock2	UTSW	11	34,732,371 (GRCm38)	missense	possibly damaging	0.81
R4135:Dock2	UTSW	11	34,714,501 (GRCm38)	missense	possibly damaging	0.83
R4598:Dock2	UTSW	11	34,239,536 (GRCm38)	missense	probably damaging	1.00
R4599:Dock2	UTSW	11	34,239,536 (GRCm38)	missense	probably damaging	1.00
R4715:Dock2	UTSW	11	34,294,118 (GRCm38)	missense	probably damaging	1.00
R4722:Dock2	UTSW	11	34,695,471 (GRCm38)	missense	probably damaging	1.00
R4742:Dock2	UTSW	11	34,294,170 (GRCm38)	critical splice acceptor site	probably null
R4830:Dock2	UTSW	11	34,273,767 (GRCm38)	splice site	probably null
R4884:Dock2	UTSW	11	34,266,248 (GRCm38)	missense	probably damaging	1.00
R4990:Dock2	UTSW	11	34,695,251 (GRCm38)	missense	probably damaging	1.00
R5334:Dock2	UTSW	11	34,228,643 (GRCm38)	missense	probably benign	0.00
R5570:Dock2	UTSW	11	34,727,406 (GRCm38)	missense	probably damaging	1.00
R5602:Dock2	UTSW	11	34,254,391 (GRCm38)	missense	probably benign	0.16
R5681:Dock2	UTSW	11	34,249,836 (GRCm38)	missense	probably benign	0.06
R5809:Dock2	UTSW	11	34,262,445 (GRCm38)	missense	probably benign
R5860:Dock2	UTSW	11	34,256,562 (GRCm38)	missense	probably damaging	1.00
R6111:Dock2	UTSW	11	34,708,787 (GRCm38)	missense	probably damaging	0.99
R6155:Dock2	UTSW	11	34,294,123 (GRCm38)	missense	probably benign	0.06
R6156:Dock2	UTSW	11	34,247,789 (GRCm38)	missense	possibly damaging	0.51
R6173:Dock2	UTSW	11	34,262,388 (GRCm38)	missense	probably null	0.80
R6182:Dock2	UTSW	11	34,229,476 (GRCm38)	missense	probably damaging	0.97
R6188:Dock2	UTSW	11	34,503,396 (GRCm38)	missense	probably damaging	0.98
R6191:Dock2	UTSW	11	34,231,652 (GRCm38)	missense	possibly damaging	0.79
R6283:Dock2	UTSW	11	34,707,325 (GRCm38)	missense	probably damaging	0.99
R6395:Dock2	UTSW	11	34,232,874 (GRCm38)	missense	probably damaging	1.00
R6465:Dock2	UTSW	11	34,503,413 (GRCm38)	missense	probably damaging	1.00
R6500:Dock2	UTSW	11	34,362,822 (GRCm38)	missense	possibly damaging	0.76
R6561:Dock2	UTSW	11	34,687,538 (GRCm38)	missense	probably damaging	1.00
R6745:Dock2	UTSW	11	34,705,843 (GRCm38)	missense	probably damaging	1.00
R6745:Dock2	UTSW	11	34,705,842 (GRCm38)	missense	probably damaging	1.00
R6880:Dock2	UTSW	11	34,688,452 (GRCm38)	critical splice donor site	probably null
R6913:Dock2	UTSW	11	34,756,222 (GRCm38)	missense	probably damaging	1.00
R6997:Dock2	UTSW	11	34,464,922 (GRCm38)	missense	probably damaging	1.00
R7057:Dock2	UTSW	11	34,695,217 (GRCm38)	missense	probably benign	0.00
R7057:Dock2	UTSW	11	34,227,684 (GRCm38)	missense	probably benign	0.10
R7134:Dock2	UTSW	11	34,310,363 (GRCm38)	missense	probably benign	0.03
R7188:Dock2	UTSW	11	34,239,675 (GRCm38)	missense	possibly damaging	0.87
R7239:Dock2	UTSW	11	34,231,677 (GRCm38)	missense	probably benign	0.00
R7247:Dock2	UTSW	11	34,714,513 (GRCm38)	nonsense	probably null
R7250:Dock2	UTSW	11	34,695,293 (GRCm38)	missense	probably damaging	1.00
R7250:Dock2	UTSW	11	34,695,205 (GRCm38)	missense	probably benign	0.01
R7271:Dock2	UTSW	11	34,273,750 (GRCm38)	missense	possibly damaging	0.95
R7284:Dock2	UTSW	11	34,230,672 (GRCm38)	missense	probably benign	0.01
R7397:Dock2	UTSW	11	34,718,989 (GRCm38)	missense	probably benign	0.00
R7464:Dock2	UTSW	11	34,695,278 (GRCm38)	missense	probably damaging	0.99
R7512:Dock2	UTSW	11	34,312,542 (GRCm38)	missense	possibly damaging	0.95
R7556:Dock2	UTSW	11	34,720,951 (GRCm38)	missense	probably benign	0.43
R7663:Dock2	UTSW	11	34,721,027 (GRCm38)	missense	probably damaging	1.00
R7779:Dock2	UTSW	11	34,714,455 (GRCm38)	missense	probably benign	0.38
R7797:Dock2	UTSW	11	34,282,652 (GRCm38)	missense	probably damaging	0.98
R7855:Dock2	UTSW	11	34,273,698 (GRCm38)	missense	probably damaging	1.00
R7922:Dock2	UTSW	11	34,707,327 (GRCm38)	missense	probably benign	0.29
R7932:Dock2	UTSW	11	34,267,998 (GRCm38)	missense	probably benign	0.00
R8013:Dock2	UTSW	11	34,705,850 (GRCm38)	missense	probably damaging	0.96
R8192:Dock2	UTSW	11	34,732,339 (GRCm38)	critical splice donor site	probably null
R8244:Dock2	UTSW	11	34,695,453 (GRCm38)	missense	probably damaging	1.00
R8307:Dock2	UTSW	11	34,310,362 (GRCm38)	missense	possibly damaging	0.95
R8418:Dock2	UTSW	11	34,718,968 (GRCm38)	missense	probably benign	0.01
R8460:Dock2	UTSW	11	34,230,825 (GRCm38)	critical splice acceptor site	probably null
R8495:Dock2	UTSW	11	34,231,622 (GRCm38)	missense	probably benign	0.14
R8556:Dock2	UTSW	11	34,262,457 (GRCm38)	missense	possibly damaging	0.84
R8690:Dock2	UTSW	11	34,727,460 (GRCm38)	nonsense	probably null
R8743:Dock2	UTSW	11	34,273,252 (GRCm38)	nonsense	probably null
R8757:Dock2	UTSW	11	34,695,240 (GRCm38)	missense	probably benign	0.13
R8759:Dock2	UTSW	11	34,695,240 (GRCm38)	missense	probably benign	0.13
R8793:Dock2	UTSW	11	34,501,215 (GRCm38)	missense	probably benign	0.00
R8882:Dock2	UTSW	11	34,704,609 (GRCm38)	frame shift	probably null
R8885:Dock2	UTSW	11	34,310,396 (GRCm38)	missense	probably benign	0.01
R8943:Dock2	UTSW	11	34,708,819 (GRCm38)	missense	possibly damaging	0.63
R9171:Dock2	UTSW	11	34,698,843 (GRCm38)	missense	probably benign	0.12
R9182:Dock2	UTSW	11	34,310,398 (GRCm38)	missense	possibly damaging	0.51
R9203:Dock2	UTSW	11	34,731,539 (GRCm38)	missense	possibly damaging	0.92
R9310:Dock2	UTSW	11	34,294,139 (GRCm38)	missense	possibly damaging	0.71
R9388:Dock2	UTSW	11	34,262,460 (GRCm38)	missense	possibly damaging	0.70
R9490:Dock2	UTSW	11	34,698,755 (GRCm38)	missense	possibly damaging	0.90
R9568:Dock2	UTSW	11	34,708,811 (GRCm38)	missense	possibly damaging	0.83
R9593:Dock2	UTSW	11	34,228,607 (GRCm38)	missense	probably benign	0.34
R9694:Dock2	UTSW	11	34,268,054 (GRCm38)	missense	probably benign
R9697:Dock2	UTSW	11	34,254,417 (GRCm38)	missense	probably benign
R9753:Dock2	UTSW	11	34,273,673 (GRCm38)	missense	possibly damaging	0.68
R9783:Dock2	UTSW	11	34,258,128 (GRCm38)	missense	possibly damaging	0.83
X0017:Dock2	UTSW	11	34,266,271 (GRCm38)	missense	probably benign	0.08
X0018:Dock2	UTSW	11	34,232,833 (GRCm38)	missense	possibly damaging	0.65
X0058:Dock2	UTSW	11	34,256,564 (GRCm38)	missense	probably damaging	1.00
X0066:Dock2	UTSW	11	34,310,357 (GRCm38)	missense	possibly damaging	0.95
Z1088:Dock2	UTSW	11	34,692,382 (GRCm38)	missense	probably damaging	1.00
Z1088:Dock2	UTSW	11	34,438,300 (GRCm38)	missense	probably benign	0.14
Z1088:Dock2	UTSW	11	34,695,212 (GRCm38)	nonsense	probably null
Z1176:Dock2	UTSW	11	34,718,924 (GRCm38)	missense	probably benign	0.04
Z1177:Dock2	UTSW	11	34,312,553 (GRCm38)	missense	possibly damaging	0.68

Posted On

2015-04-16