Incidental Mutation 'IGL02477:Zmym6'
ID 295006
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Zmym6
Ensembl Gene ENSMUSG00000042408
Gene Name zinc finger, MYM-type 6
Synonyms 9330177P20Rik, Zfp258, D4Wsu24e
Accession Numbers
Essential gene? Non essential (E-score: 0.000) question?
Stock # IGL02477
Quality Score
Status
Chromosome 4
Chromosomal Location 126971176-127018165 bp(+) (GRCm39)
Type of Mutation nonsense
DNA Base Change (assembly) C to T at 126972295 bp (GRCm39)
Zygosity Heterozygous
Amino Acid Change Glutamine to Stop codon at position 16 (Q16*)
Ref Sequence ENSEMBL: ENSMUSP00000092303 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000046751] [ENSMUST00000094713]
AlphaFold Q8BS54
Predicted Effect probably null
Transcript: ENSMUST00000046751
AA Change: Q16*
SMART Domains Protein: ENSMUSP00000045366
Gene: ENSMUSG00000042408
AA Change: Q16*

DomainStartEndE-ValueType
Blast:TRASH 77 113 1e-12 BLAST
TRASH 123 163 1.18e-1 SMART
TRASH 197 231 5.47e3 SMART
TRASH 241 277 4.01e1 SMART
TRASH 349 385 2.46e1 SMART
TRASH 391 426 3.32e2 SMART
TRASH 434 472 2.91e-1 SMART
TRASH 478 513 9.99e0 SMART
low complexity region 602 612 N/A INTRINSIC
low complexity region 642 656 N/A INTRINSIC
Predicted Effect probably null
Transcript: ENSMUST00000094713
AA Change: Q16*
SMART Domains Protein: ENSMUSP00000092303
Gene: ENSMUSG00000042408
AA Change: Q16*

DomainStartEndE-ValueType
Blast:TRASH 77 113 1e-12 BLAST
TRASH 123 163 1.18e-1 SMART
TRASH 197 231 5.47e3 SMART
TRASH 262 293 6.03e2 SMART
TRASH 299 334 3.32e2 SMART
TRASH 342 380 2.91e-1 SMART
TRASH 386 421 9.99e0 SMART
low complexity region 510 520 N/A INTRINSIC
low complexity region 550 564 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000129926
Predicted Effect noncoding transcript
Transcript: ENSMUST00000151461
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 42 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4921539E11Rik T A 4: 103,127,943 (GRCm39) I61F probably benign Het
Abr T C 11: 76,352,186 (GRCm39) K280E probably damaging Het
Acaca T C 11: 84,197,994 (GRCm39) probably benign Het
Cep131 C T 11: 119,961,406 (GRCm39) V582I probably damaging Het
Colec12 A G 18: 9,859,858 (GRCm39) N613D unknown Het
Cyp4f39 A G 17: 32,708,619 (GRCm39) T389A probably benign Het
D630003M21Rik T C 2: 158,059,408 (GRCm39) N164S probably benign Het
Eef1akmt2 A T 7: 132,452,318 (GRCm39) probably null Het
Elp3 T C 14: 65,800,760 (GRCm39) T283A probably benign Het
Fads3 C A 19: 10,033,806 (GRCm39) P397Q probably damaging Het
Fam171a1 T C 2: 3,203,612 (GRCm39) V198A possibly damaging Het
Fam171a2 T C 11: 102,330,854 (GRCm39) I208M probably benign Het
Fbxw17 G A 13: 50,577,853 (GRCm39) V119M possibly damaging Het
Gtf2ird1 G A 5: 134,408,832 (GRCm39) T140M probably damaging Het
Hspa14 C T 2: 3,497,661 (GRCm39) S277N probably damaging Het
Hspg2 C T 4: 137,271,823 (GRCm39) probably benign Het
Ing2 G T 8: 48,122,303 (GRCm39) R82S possibly damaging Het
Kat6a A G 8: 23,419,316 (GRCm39) Y693C probably damaging Het
Kcna7 A G 7: 45,059,047 (GRCm39) M445V probably benign Het
Lifr T G 15: 7,216,404 (GRCm39) I793S probably damaging Het
Lrrd1 T A 5: 3,915,770 (GRCm39) M789K probably benign Het
Myom3 T A 4: 135,506,679 (GRCm39) L484Q probably benign Het
Nav2 T A 7: 49,232,623 (GRCm39) M1860K probably damaging Het
Nipbl C T 15: 8,353,131 (GRCm39) probably null Het
Nsun7 T A 5: 66,433,992 (GRCm39) I214K probably damaging Het
Or5k17 T C 16: 58,746,126 (GRCm39) I269M probably benign Het
Or8c20 C T 9: 38,260,421 (GRCm39) S8L probably benign Het
Osm T A 11: 4,189,604 (GRCm39) N129K probably damaging Het
Plce1 C T 19: 38,707,997 (GRCm39) probably benign Het
Plch1 A G 3: 63,660,714 (GRCm39) F302L probably damaging Het
Pld2 T C 11: 70,431,751 (GRCm39) V27A possibly damaging Het
Prex2 A G 1: 11,274,378 (GRCm39) D1350G probably benign Het
Psme4 T A 11: 30,792,083 (GRCm39) V1190D probably damaging Het
Sema3g G T 14: 30,949,823 (GRCm39) R668L probably damaging Het
Sprr2f T A 3: 92,273,204 (GRCm39) M1K probably null Het
Sult6b2 G A 6: 142,747,447 (GRCm39) P101S probably damaging Het
Trem3 G A 17: 48,556,864 (GRCm39) V112I probably benign Het
Ttll9 T A 2: 152,842,117 (GRCm39) F324I possibly damaging Het
Ttn T A 2: 76,557,104 (GRCm39) D29967V probably damaging Het
Ubr4 A G 4: 139,163,516 (GRCm39) K2639E probably damaging Het
Vwce T C 19: 10,641,982 (GRCm39) probably null Het
Zbtb14 T A 17: 69,694,690 (GRCm39) D129E probably benign Het
Other mutations in Zmym6
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00430:Zmym6 APN 4 126,995,742 (GRCm39) nonsense probably null
IGL00486:Zmym6 APN 4 127,017,978 (GRCm39) utr 5 prime probably benign
IGL01017:Zmym6 APN 4 126,982,152 (GRCm39) missense probably benign 0.00
IGL01385:Zmym6 APN 4 127,017,899 (GRCm39) missense probably benign 0.02
IGL01577:Zmym6 APN 4 126,999,223 (GRCm39) missense probably damaging 1.00
IGL01654:Zmym6 APN 4 127,017,519 (GRCm39) missense probably damaging 1.00
IGL01736:Zmym6 APN 4 127,002,437 (GRCm39) missense probably damaging 1.00
IGL01824:Zmym6 APN 4 127,002,499 (GRCm39) missense probably damaging 0.99
IGL01916:Zmym6 APN 4 127,017,549 (GRCm39) missense probably damaging 0.98
IGL01985:Zmym6 APN 4 126,994,541 (GRCm39) missense probably damaging 1.00
IGL02056:Zmym6 APN 4 126,997,207 (GRCm39) missense probably damaging 1.00
IGL02754:Zmym6 APN 4 127,003,764 (GRCm39) splice site probably benign
IGL03344:Zmym6 APN 4 127,014,314 (GRCm39) missense probably damaging 1.00
IGL03412:Zmym6 APN 4 126,986,731 (GRCm39) missense probably damaging 1.00
R0335:Zmym6 UTSW 4 127,016,601 (GRCm39) missense probably damaging 1.00
R0448:Zmym6 UTSW 4 127,002,487 (GRCm39) missense probably benign 0.01
R0463:Zmym6 UTSW 4 127,016,565 (GRCm39) missense probably damaging 0.98
R0538:Zmym6 UTSW 4 127,017,162 (GRCm39) missense probably benign 0.21
R0789:Zmym6 UTSW 4 127,016,615 (GRCm39) missense possibly damaging 0.52
R0798:Zmym6 UTSW 4 126,997,316 (GRCm39) missense probably benign 0.00
R1311:Zmym6 UTSW 4 127,017,151 (GRCm39) missense probably damaging 1.00
R1351:Zmym6 UTSW 4 127,016,798 (GRCm39) missense probably benign 0.00
R1429:Zmym6 UTSW 4 127,017,672 (GRCm39) missense probably damaging 1.00
R1636:Zmym6 UTSW 4 127,017,560 (GRCm39) missense probably damaging 0.99
R1666:Zmym6 UTSW 4 127,016,652 (GRCm39) missense probably damaging 0.98
R1919:Zmym6 UTSW 4 126,997,207 (GRCm39) missense probably damaging 1.00
R2058:Zmym6 UTSW 4 126,982,208 (GRCm39) nonsense probably null
R3957:Zmym6 UTSW 4 127,017,089 (GRCm39) missense possibly damaging 0.68
R3978:Zmym6 UTSW 4 127,017,348 (GRCm39) missense possibly damaging 0.71
R4417:Zmym6 UTSW 4 126,986,781 (GRCm39) missense probably damaging 1.00
R4801:Zmym6 UTSW 4 127,017,009 (GRCm39) missense probably benign 0.19
R4802:Zmym6 UTSW 4 127,017,009 (GRCm39) missense probably benign 0.19
R5052:Zmym6 UTSW 4 127,017,767 (GRCm39) missense possibly damaging 0.92
R5105:Zmym6 UTSW 4 127,017,551 (GRCm39) missense probably benign 0.33
R5217:Zmym6 UTSW 4 126,999,167 (GRCm39) missense possibly damaging 0.76
R5682:Zmym6 UTSW 4 126,998,200 (GRCm39) missense probably damaging 1.00
R5841:Zmym6 UTSW 4 126,994,463 (GRCm39) missense possibly damaging 0.71
R5991:Zmym6 UTSW 4 127,002,266 (GRCm39) splice site probably null
R6478:Zmym6 UTSW 4 127,017,176 (GRCm39) missense possibly damaging 0.86
R7014:Zmym6 UTSW 4 127,017,337 (GRCm39) nonsense probably null
R7287:Zmym6 UTSW 4 127,016,775 (GRCm39) missense possibly damaging 0.50
R7290:Zmym6 UTSW 4 127,017,294 (GRCm39) missense possibly damaging 0.73
R7371:Zmym6 UTSW 4 126,998,106 (GRCm39) missense probably damaging 1.00
R7967:Zmym6 UTSW 4 127,016,453 (GRCm39) missense probably benign 0.03
R8237:Zmym6 UTSW 4 127,016,544 (GRCm39) missense probably damaging 0.99
R8306:Zmym6 UTSW 4 127,016,355 (GRCm39) missense probably damaging 1.00
R8312:Zmym6 UTSW 4 127,017,627 (GRCm39) missense probably damaging 1.00
R9090:Zmym6 UTSW 4 127,017,854 (GRCm39) missense probably damaging 0.99
R9216:Zmym6 UTSW 4 127,002,500 (GRCm39) missense probably benign 0.00
R9271:Zmym6 UTSW 4 127,017,854 (GRCm39) missense probably damaging 0.99
R9695:Zmym6 UTSW 4 127,016,340 (GRCm39) missense probably benign
X0025:Zmym6 UTSW 4 127,016,143 (GRCm39) missense possibly damaging 0.60
X0067:Zmym6 UTSW 4 126,998,107 (GRCm39) missense probably damaging 1.00
Z1177:Zmym6 UTSW 4 127,017,590 (GRCm39) missense not run
Posted On 2015-04-16