Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL00936:Or5b113'

29515

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Or5b113

Ensembl Gene

ENSMUSG00000049015

Gene Name

olfactory receptor family 5 subfamily B member 113

Synonyms

GA_x6K02T2RE5P-3695694-3696620, Olfr1467, MOR202-15

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.093) question?

Stock #

IGL00936

Quality Score

Status

Chromosome

Chromosomal Location

13341994-13342920 bp(+) (GRCm39)

Type of Mutation

utr 5 prime

DNA Base Change (assembly)

T to A at 13341988 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000149487 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000054687] [ENSMUST00000215096]

AlphaFold

Q8VFW1

Predicted Effect

probably benign
Transcript: ENSMUST00000054687

SMART Domains

Protein: ENSMUSP00000061580
Gene: ENSMUSG00000049015

Domain	Start	End	E-Value	Type
Pfam:7tm_4	30	307	6.6e-48	PFAM
Pfam:7tm_1	40	289	7.4e-20	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000215096

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

Allele List at MGI

Other mutations in this stock

Total: 8 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930562C15Rik	A	G	16: 4,682,510 (GRCm39)	T1053A	probably benign	Het
Col13a1	A	G	10: 61,712,069 (GRCm39)	M332T	probably damaging	Het
Cstdc1	A	C	2: 148,627,724 (GRCm39)	T124P	probably benign	Het
Cyth4	A	G	15: 78,504,113 (GRCm39)	E361G	probably benign	Het
Mrps22	T	C	9: 98,479,034 (GRCm39)	T114A	possibly damaging	Het
Nup155	T	C	15: 8,157,889 (GRCm39)		probably benign	Het
Slc35g3	T	C	11: 69,651,317 (GRCm39)		probably null	Het
Taar7f	T	C	10: 23,926,066 (GRCm39)	V220A	probably benign	Het

Other mutations in Or5b113

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01109:Or5b113	APN	19	13,342,063 (GRCm39)	missense	probably benign
IGL01939:Or5b113	APN	19	13,342,807 (GRCm39)	missense	probably benign	0.14
IGL02188:Or5b113	APN	19	13,342,643 (GRCm39)	missense	probably damaging	0.98
IGL02188:Or5b113	APN	19	13,342,396 (GRCm39)	missense	probably benign	0.39
IGL03223:Or5b113	APN	19	13,342,645 (GRCm39)	missense	probably benign
R0456:Or5b113	UTSW	19	13,342,102 (GRCm39)	missense	probably damaging	0.98
R1066:Or5b113	UTSW	19	13,342,451 (GRCm39)	missense	probably benign
R1189:Or5b113	UTSW	19	13,342,543 (GRCm39)	missense	probably benign	0.03
R1668:Or5b113	UTSW	19	13,342,234 (GRCm39)	missense	probably benign	0.00
R1754:Or5b113	UTSW	19	13,342,717 (GRCm39)	missense	probably damaging	1.00
R1860:Or5b113	UTSW	19	13,342,705 (GRCm39)	missense	possibly damaging	0.80
R1861:Or5b113	UTSW	19	13,342,705 (GRCm39)	missense	possibly damaging	0.80
R2181:Or5b113	UTSW	19	13,342,438 (GRCm39)	missense	probably benign	0.08
R2219:Or5b113	UTSW	19	13,342,901 (GRCm39)	missense	possibly damaging	0.88
R2516:Or5b113	UTSW	19	13,342,557 (GRCm39)	nonsense	probably null
R4757:Or5b113	UTSW	19	13,342,810 (GRCm39)	missense	probably benign	0.23
R5206:Or5b113	UTSW	19	13,342,429 (GRCm39)	missense	possibly damaging	0.91
R5376:Or5b113	UTSW	19	13,342,762 (GRCm39)	missense	possibly damaging	0.95
R5647:Or5b113	UTSW	19	13,342,541 (GRCm39)	missense	probably damaging	1.00
R5724:Or5b113	UTSW	19	13,342,515 (GRCm39)	missense	possibly damaging	0.62
R5741:Or5b113	UTSW	19	13,342,847 (GRCm39)	missense	probably damaging	0.97
R5906:Or5b113	UTSW	19	13,342,369 (GRCm39)	missense	probably damaging	1.00
R6636:Or5b113	UTSW	19	13,342,589 (GRCm39)	missense	probably benign	0.06
R6637:Or5b113	UTSW	19	13,342,589 (GRCm39)	missense	probably benign	0.06
R7000:Or5b113	UTSW	19	13,341,987 (GRCm39)	start gained	probably benign
R7254:Or5b113	UTSW	19	13,342,475 (GRCm39)	missense	probably benign	0.28
R7325:Or5b113	UTSW	19	13,342,001 (GRCm39)	missense	probably benign	0.00
R7773:Or5b113	UTSW	19	13,342,598 (GRCm39)	missense	probably benign	0.07
R7828:Or5b113	UTSW	19	13,342,510 (GRCm39)	missense	probably benign	0.10
R9081:Or5b113	UTSW	19	13,342,019 (GRCm39)	missense	probably benign	0.12
R9135:Or5b113	UTSW	19	13,342,755 (GRCm39)	missense	possibly damaging	0.46
R9151:Or5b113	UTSW	19	13,342,222 (GRCm39)	missense	possibly damaging	0.95
R9470:Or5b113	UTSW	19	13,342,115 (GRCm39)	missense	probably damaging	1.00
R9792:Or5b113	UTSW	19	13,342,514 (GRCm39)	missense	probably damaging	0.99
R9793:Or5b113	UTSW	19	13,342,514 (GRCm39)	missense	probably damaging	0.99
Z1176:Or5b113	UTSW	19	13,342,280 (GRCm39)	missense	probably damaging	1.00
Z1176:Or5b113	UTSW	19	13,342,279 (GRCm39)	missense	probably damaging	1.00

Posted On

2013-04-17