Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02484:Vmn2r32'

295356

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r32

Ensembl Gene

ENSMUSG00000096743

Gene Name

vomeronasal 2, receptor 32

Synonyms

V2r5

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.190) question?

Stock #

IGL02484

Quality Score

Status

Chromosome

Chromosomal Location

7463015-7479973 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 7464117 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Glycine to Aspartic acid at position 804 (G804D)

Ref Sequence

ENSEMBL: ENSMUSP00000092462 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000094866]

AlphaFold

K7N686

Predicted Effect

probably damaging
Transcript: ENSMUST00000094866
AA Change: G804D

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000092462
Gene: ENSMUSG00000096743
AA Change: G804D

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC
Pfam:ANF_receptor	73	470	3.6e-33	PFAM
Pfam:NCD3G	512	565	8.1e-21	PFAM
Pfam:7tm_3	598	833	9.5e-55	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 45 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930432E11Rik	A	C	7: 29,563,352 (GRCm38)		noncoding transcript	Het
Araf	A	G	X: 20,853,909 (GRCm38)		probably benign	Het
Arrb2	T	A	11: 70,439,474 (GRCm38)	V308E	probably damaging	Het
Asap3	A	G	4: 136,229,457 (GRCm38)		probably benign	Het
Astn2	G	A	4: 65,992,279 (GRCm38)		probably benign	Het
Cactin	T	A	10: 81,322,974 (GRCm38)	I258N	probably benign	Het
Catsperg1	T	C	7: 29,210,920 (GRCm38)		probably benign	Het
Ccna1	C	T	3: 55,048,494 (GRCm38)	D146N	probably benign	Het
Chrna3	T	C	9: 55,015,537 (GRCm38)	Y329C	probably damaging	Het
Ctps2	G	A	X: 162,910,009 (GRCm38)	G56D	probably damaging	Het
Cyp4b1	T	C	4: 115,647,557 (GRCm38)	D44G	probably benign	Het
D3Ertd751e	A	G	3: 41,753,720 (GRCm38)		probably null	Het
Daxx	T	C	17: 33,912,242 (GRCm38)	V381A	probably damaging	Het
Dhx37	T	A	5: 125,419,337 (GRCm38)	I714F	possibly damaging	Het
Dnah7b	T	C	1: 46,195,318 (GRCm38)	V1470A	probably damaging	Het
Efl1	T	C	7: 82,683,039 (GRCm38)	I297T	probably damaging	Het
Fam26f	T	C	10: 34,126,404 (GRCm38)	T228A	probably benign	Het
Fnd3c2	A	T	X: 106,245,486 (GRCm38)	H442Q	probably damaging	Het
Glp2r	A	C	11: 67,740,166 (GRCm38)	V126G	possibly damaging	Het
Gm5699	G	T	1: 30,998,762 (GRCm38)		noncoding transcript	Het
Gpt2	A	G	8: 85,516,233 (GRCm38)	D298G	probably damaging	Het
Gse1	G	T	8: 120,575,262 (GRCm38)		probably benign	Het
Hand1	T	C	11: 57,831,594 (GRCm38)	T65A	probably benign	Het
Ints8	G	A	4: 11,208,834 (GRCm38)	Q955*	probably null	Het
Lrguk	C	T	6: 34,092,791 (GRCm38)	P534S	probably damaging	Het
Lrp6	A	G	6: 134,541,923 (GRCm38)	F60L	probably benign	Het
Mamld1	T	C	X: 71,118,652 (GRCm38)	I423T	possibly damaging	Het
Mrpl22	G	A	11: 58,173,062 (GRCm38)	S36N	possibly damaging	Het
Mug2	A	G	6: 122,072,753 (GRCm38)	E915G	probably damaging	Het
Olfr1442	T	C	19: 12,674,859 (GRCm38)	F218S	possibly damaging	Het
Olfr493	C	T	7: 108,346,606 (GRCm38)	R125Q	probably damaging	Het
Oosp2	T	C	19: 11,651,483 (GRCm38)	T85A	probably benign	Het
Pde4c	T	A	8: 70,748,052 (GRCm38)		probably benign	Het
Pdxdc1	T	C	16: 13,876,081 (GRCm38)	E159G	possibly damaging	Het
Poln	T	C	5: 34,129,377 (GRCm38)	E149G	probably damaging	Het
Pou5f2	T	G	13: 78,025,905 (GRCm38)	L322R	probably damaging	Het
Ppm1k	A	T	6: 57,525,012 (GRCm38)	S55R	possibly damaging	Het
Ptges2	T	A	2: 32,397,707 (GRCm38)	I149N	probably damaging	Het
Pus7l	A	G	15: 94,529,488 (GRCm38)	V471A	possibly damaging	Het
Raet1e	A	T	10: 22,180,767 (GRCm38)	M81L	probably benign	Het
Sipa1l3	A	G	7: 29,399,531 (GRCm38)	S438P	probably damaging	Het
Skint5	T	A	4: 113,942,553 (GRCm38)	K126*	probably null	Het
Stfa2	T	C	16: 36,405,207 (GRCm38)	T37A	probably damaging	Het
Ttll12	A	G	15: 83,581,696 (GRCm38)	I433T	possibly damaging	Het
Zc3h14	A	G	12: 98,774,301 (GRCm38)	T84A	probably benign	Het

Other mutations in Vmn2r32

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02140:Vmn2r32	APN	7	7,476,697 (GRCm38)	missense	probably damaging	0.97
IGL02333:Vmn2r32	APN	7	7,464,144 (GRCm38)	missense	probably damaging	1.00
IGL02406:Vmn2r32	APN	7	7,476,710 (GRCm38)	missense	probably benign
IGL02428:Vmn2r32	APN	7	7,474,284 (GRCm38)	missense	probably benign	0.02
IGL03277:Vmn2r32	APN	7	7,474,252 (GRCm38)	missense	probably benign	0.23
IGL03366:Vmn2r32	APN	7	7,464,030 (GRCm38)	missense	probably damaging	0.99
R1055:Vmn2r32	UTSW	7	7,474,327 (GRCm38)	nonsense	probably null
R1695:Vmn2r32	UTSW	7	7,463,992 (GRCm38)	missense	probably benign	0.01
R2172:Vmn2r32	UTSW	7	7,474,615 (GRCm38)	missense	probably damaging	0.99
R2262:Vmn2r32	UTSW	7	7,474,619 (GRCm38)	missense	probably benign
R3150:Vmn2r32	UTSW	7	7,472,555 (GRCm38)	missense	probably benign
R4362:Vmn2r32	UTSW	7	7,479,858 (GRCm38)	nonsense	probably null
R4432:Vmn2r32	UTSW	7	7,479,919 (GRCm38)	missense	probably damaging	0.98
R4851:Vmn2r32	UTSW	7	7,479,954 (GRCm38)	missense	possibly damaging	0.59
R4949:Vmn2r32	UTSW	7	7,464,084 (GRCm38)	missense	probably benign	0.22
R5990:Vmn2r32	UTSW	7	7,479,810 (GRCm38)	missense	probably damaging	0.97
R6083:Vmn2r32	UTSW	7	7,464,210 (GRCm38)	missense	probably benign	0.15
R6084:Vmn2r32	UTSW	7	7,464,210 (GRCm38)	missense	probably benign	0.15
R6116:Vmn2r32	UTSW	7	7,464,093 (GRCm38)	missense	probably damaging	1.00
R6263:Vmn2r32	UTSW	7	7,476,692 (GRCm38)	missense	possibly damaging	0.90
R6889:Vmn2r32	UTSW	7	7,472,574 (GRCm38)	missense	possibly damaging	0.82
R7286:Vmn2r32	UTSW	7	7,479,808 (GRCm38)	missense	probably benign	0.21
R7390:Vmn2r32	UTSW	7	7,479,852 (GRCm38)	missense	probably benign	0.00
R7412:Vmn2r32	UTSW	7	7,474,213 (GRCm38)	missense	possibly damaging	0.53
R7508:Vmn2r32	UTSW	7	7,467,374 (GRCm38)	missense	possibly damaging	0.87
R8812:Vmn2r32	UTSW	7	7,474,670 (GRCm38)	missense	probably damaging	1.00
R8968:Vmn2r32	UTSW	7	7,474,205 (GRCm38)	missense	probably benign	0.00
R9331:Vmn2r32	UTSW	7	7,464,403 (GRCm38)	nonsense	probably null
R9358:Vmn2r32	UTSW	7	7,474,198 (GRCm38)	missense	probably damaging	1.00
Z1177:Vmn2r32	UTSW	7	7,474,161 (GRCm38)	missense	probably damaging	0.98

Posted On

2015-04-16