Incidental Mutation 'IGL02485:Gm17175'
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm17175
Ensembl Gene ENSMUSG00000091142
Gene Namepredicted gene 17175
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.062) question?
Stock #IGL02485
Quality Score
Chromosomal Location51568892-51574063 bp(-) (GRCm38)
Type of Mutationutr 3 prime
DNA Base Change (assembly) T to C at 51569611 bp
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000127078 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000096170] [ENSMUST00000162998] [ENSMUST00000172117]
Predicted Effect probably benign
Transcript: ENSMUST00000096170
SMART Domains Protein: ENSMUSP00000093884
Gene: ENSMUSG00000079244

Pfam:Takusan 56 144 1.3e-21 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000162998
SMART Domains Protein: ENSMUSP00000125409
Gene: ENSMUSG00000068399

Pfam:Takusan 35 115 2.2e-25 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000172117
SMART Domains Protein: ENSMUSP00000127078
Gene: ENSMUSG00000091142

Pfam:Takusan 23 103 3.3e-26 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 25 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4930430A15Rik A T 2: 111,228,325 V94E probably damaging Het
Agl A G 3: 116,779,080 S841P probably benign Het
BC003331 A G 1: 150,363,489 probably null Het
Cd59b A C 2: 104,081,104 probably benign Het
Dopey2 T C 16: 93,770,822 L1379P probably damaging Het
Ercc2 G A 7: 19,394,045 A433T possibly damaging Het
Gm5150 A T 3: 15,990,752 I103N probably damaging Het
Igf1 A G 10: 87,864,746 M11V probably benign Het
Incenp T C 19: 9,893,368 N299S unknown Het
Maneal A T 4: 124,856,770 S398T probably damaging Het
Map1a A G 2: 121,299,288 N195S probably damaging Het
Mars2 T C 1: 55,237,591 F118L possibly damaging Het
Mast4 A G 13: 102,735,496 S2263P probably benign Het
Mrgprb1 C A 7: 48,447,717 R149L possibly damaging Het
Myo1d T C 11: 80,666,581 D511G probably damaging Het
Ntan1 T C 16: 13,834,676 probably benign Het
Nxf2 A G X: 134,956,467 F158L probably damaging Het
Olfr1513 T A 14: 52,350,044 M1L possibly damaging Het
Trpm1 C T 7: 64,269,114 A734V possibly damaging Het
Upf2 G A 2: 6,027,291 E883K unknown Het
Ush1c T C 7: 46,229,250 I83V probably damaging Het
Vmn2r60 C A 7: 42,195,466 T751N possibly damaging Het
Zfp146 A G 7: 30,162,590 I9T probably benign Het
Zfp592 G A 7: 81,037,970 probably benign Het
Zswim8 C T 14: 20,711,887 L243F probably damaging Het
Other mutations in Gm17175
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00966:Gm17175 APN 14 51573069 missense possibly damaging 0.77
IGL01347:Gm17175 APN 14 51570850 missense probably damaging 0.99
IGL01553:Gm17175 APN 14 51570822 missense probably benign 0.00
IGL02436:Gm17175 APN 14 51569651 utr 3 prime probably benign
IGL03171:Gm17175 APN 14 51571608 missense probably damaging 1.00
R4120:Gm17175 UTSW 14 51573077 missense probably damaging 0.97
R4614:Gm17175 UTSW 14 51571585 missense probably benign 0.28
R6496:Gm17175 UTSW 14 51573077 missense probably benign 0.05
R6817:Gm17175 UTSW 14 51573021 missense possibly damaging 0.91
R7000:Gm17175 UTSW 14 51573961 start codon destroyed probably null
R7814:Gm17175 UTSW 14 51574035 start gained probably benign
R8074:Gm17175 UTSW 14 51571623 missense probably damaging 0.97
R8423:Gm17175 UTSW 14 51571613 missense possibly damaging 0.80
Posted On2015-04-16