Incidental Mutation 'IGL02500:Sspo'
ID 296009
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Sspo
Ensembl Gene ENSMUSG00000029797
Gene Name SCO-spondin
Synonyms Scospondin, C79529
Accession Numbers
Essential gene? Non essential (E-score: 0.000) question?
Stock # IGL02500
Quality Score
Status
Chromosome 6
Chromosomal Location 48448229-48501250 bp(+) (GRCm38)
Type of Mutation nonsense
DNA Base Change (assembly) C to A at 48478379 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change Cysteine to Stop codon at position 3047 (C3047*)
Ref Sequence ENSEMBL: ENSMUSP00000148570 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000043676] [ENSMUST00000169350] [ENSMUST00000212740]
AlphaFold no structure available at present
Predicted Effect probably null
Transcript: ENSMUST00000043676
AA Change: C2913*
SMART Domains Protein: ENSMUSP00000047991
Gene: ENSMUSG00000029797
AA Change: C2913*

DomainStartEndE-ValueType
signal peptide 1 17 N/A INTRINSIC
low complexity region 126 135 N/A INTRINSIC
Pfam:VWD 154 219 7.4e-11 PFAM
C8 267 346 2.3e-10 SMART
Pfam:TIL 349 404 3.2e-13 PFAM
VWC 406 448 2e-1 SMART
VWD 433 593 5.08e-29 SMART
C8 631 703 2.14e-28 SMART
Pfam:TIL 706 759 5.8e-11 PFAM
VWC 856 924 4.76e-2 SMART
VWD 883 1042 9.59e-48 SMART
C8 1076 1150 3.62e-26 SMART
Pfam:TIL 1153 1209 2.6e-13 PFAM
LDLa 1253 1291 2.29e-13 SMART
LDLa 1293 1328 1.87e-9 SMART
LDLa 1329 1366 5.77e-10 SMART
LDLa 1369 1408 1.52e-9 SMART
LDLa 1442 1479 2.55e-11 SMART
LDLa 1480 1520 5.6e-8 SMART
LDLa 1533 1574 2.29e-4 SMART
TSP1 1575 1626 6.47e-13 SMART
TSP1 1631 1686 1.35e-10 SMART
Pfam:TIL 1690 1746 3.1e-9 PFAM
TSP1 1774 1827 6.94e-2 SMART
VWC 1829 1886 4.95e-9 SMART
low complexity region 1901 1911 N/A INTRINSIC
FA58C 1928 2085 1.4e-2 SMART
LDLa 2091 2128 1.48e-7 SMART
LDLa 2242 2279 5.68e-9 SMART
LDLa 2299 2336 5.77e-10 SMART
TSP1 2339 2389 1.42e-9 SMART
TSP1 2394 2446 6.36e-21 SMART
Pfam:TIL 2460 2511 5.7e-10 PFAM
VWC 2513 2567 2.48e-1 SMART
TSP1 2554 2605 3.07e-14 SMART
TSP1 2611 2664 4.05e-5 SMART
TSP1 2669 2719 1.83e-12 SMART
EGF_like 2733 2776 5.45e1 SMART
VWC 2783 2836 2.73e-11 SMART
TSP1 2823 2875 3.72e-13 SMART
TSP1 2878 2919 6.05e-4 SMART
Pfam:TIL 2926 2978 1.1e-11 PFAM
VWC 2980 3035 9.77e-2 SMART
TSP1 3022 3086 6.68e-6 SMART
TSP1 3091 3143 1.08e-14 SMART
Pfam:TIL 3147 3201 2.2e-9 PFAM
VWC 3203 3260 2.72e-1 SMART
TSP1 3247 3306 3.72e-4 SMART
TSP1 3311 3363 5.27e-4 SMART
Pfam:TIL 3365 3421 4.2e-9 PFAM
TSP1 3484 3529 1.87e-9 SMART
low complexity region 3591 3601 N/A INTRINSIC
TSP1 3660 3713 5.02e-10 SMART
TSP1 3730 3779 2.95e-7 SMART
TSP1 3796 3849 1.99e-13 SMART
TSP1 3854 3906 2.51e-10 SMART
Pfam:TIL 3909 3964 3.4e-11 PFAM
VWC 3966 4022 1.26e0 SMART
TSP1 4009 4059 4.05e-5 SMART
TSP1 4103 4155 3.19e-12 SMART
TSP1 4161 4213 2.87e-2 SMART
TSP1 4218 4269 1.45e-6 SMART
Pfam:TIL 4273 4328 2.1e-10 PFAM
TSP1 4468 4516 7.56e-5 SMART
low complexity region 4551 4562 N/A INTRINSIC
VWC 4578 4652 5.21e-1 SMART
TSP1 4619 4669 3.92e-12 SMART
Pfam:TIL 4671 4725 1.5e-11 PFAM
Pfam:TIL 4777 4835 3.1e-9 PFAM
VWC 4837 4892 1.8e-11 SMART
GHB 4904 4997 1.02e0 SMART
Predicted Effect probably null
Transcript: ENSMUST00000169350
AA Change: C3058*
SMART Domains Protein: ENSMUSP00000131401
Gene: ENSMUSG00000029797
AA Change: C3058*

DomainStartEndE-ValueType
signal peptide 1 17 N/A INTRINSIC
low complexity region 126 135 N/A INTRINSIC
VWD 185 341 4.36e-28 SMART
C8 390 469 2.3e-10 SMART
Pfam:TIL 472 527 8.6e-13 PFAM
VWC 529 571 2e-1 SMART
VWD 556 716 5.08e-29 SMART
C8 754 826 2.14e-28 SMART
Pfam:TIL 829 882 1.6e-10 PFAM
VWC 979 1047 4.76e-2 SMART
VWD 1006 1165 9.59e-48 SMART
C8 1201 1275 3.62e-26 SMART
Pfam:TIL 1278 1334 7e-13 PFAM
LDLa 1378 1416 2.29e-13 SMART
LDLa 1418 1453 1.87e-9 SMART
LDLa 1454 1491 5.77e-10 SMART
LDLa 1494 1533 1.52e-9 SMART
LDLa 1567 1604 2.55e-11 SMART
LDLa 1605 1645 5.6e-8 SMART
LDLa 1658 1699 2.29e-4 SMART
TSP1 1700 1751 6.47e-13 SMART
TSP1 1756 1811 1.35e-10 SMART
Pfam:TIL 1815 1871 8.3e-9 PFAM
VWC 1873 1928 2.42e-1 SMART
TSP1 1915 1968 6.94e-2 SMART
VWC 1970 2027 4.95e-9 SMART
low complexity region 2042 2052 N/A INTRINSIC
FA58C 2069 2226 1.4e-2 SMART
LDLa 2232 2269 1.48e-7 SMART
LDLa 2387 2424 5.68e-9 SMART
LDLa 2444 2481 5.77e-10 SMART
TSP1 2484 2534 1.42e-9 SMART
TSP1 2539 2591 6.36e-21 SMART
Pfam:TIL 2606 2656 1.8e-9 PFAM
VWC 2658 2712 2.48e-1 SMART
TSP1 2699 2750 3.07e-14 SMART
TSP1 2756 2809 4.05e-5 SMART
TSP1 2814 2864 1.83e-12 SMART
EGF_like 2878 2921 5.45e1 SMART
VWC 2928 2981 2.73e-11 SMART
TSP1 2968 3020 3.72e-13 SMART
TSP1 3023 3064 6.05e-4 SMART
Pfam:TIL 3071 3123 3e-11 PFAM
VWC 3125 3180 9.77e-2 SMART
TSP1 3167 3231 6.68e-6 SMART
TSP1 3236 3288 1.08e-14 SMART
Pfam:TIL 3292 3346 6e-9 PFAM
VWC 3348 3405 2.72e-1 SMART
TSP1 3392 3451 3.72e-4 SMART
TSP1 3456 3508 5.27e-4 SMART
Pfam:TIL 3510 3566 1.1e-8 PFAM
TSP1 3629 3674 1.87e-9 SMART
low complexity region 3734 3744 N/A INTRINSIC
TSP1 3803 3856 5.02e-10 SMART
TSP1 3873 3922 2.95e-7 SMART
TSP1 3939 3992 1.99e-13 SMART
TSP1 3997 4049 2.51e-10 SMART
Pfam:TIL 4052 4107 9.1e-11 PFAM
VWC 4109 4165 1.26e0 SMART
TSP1 4152 4202 4.05e-5 SMART
TSP1 4246 4298 3.19e-12 SMART
TSP1 4304 4356 2.87e-2 SMART
TSP1 4361 4412 1.45e-6 SMART
Pfam:TIL 4416 4471 5.6e-10 PFAM
TSP1 4611 4659 7.56e-5 SMART
low complexity region 4694 4705 N/A INTRINSIC
VWC 4721 4795 5.21e-1 SMART
TSP1 4762 4812 3.92e-12 SMART
Pfam:TIL 4814 4868 4e-11 PFAM
Pfam:TIL 4920 4978 8.4e-9 PFAM
VWC 4980 5035 1.8e-11 SMART
GHB 5050 5143 1.02e0 SMART
Predicted Effect noncoding transcript
Transcript: ENSMUST00000189910
Predicted Effect probably null
Transcript: ENSMUST00000212740
AA Change: C3047*
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 45 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abcc4 A T 14: 118,618,926 (GRCm38) I409N possibly damaging Het
Aoc3 T A 11: 101,337,389 (GRCm38) L674* probably null Het
Arhgef10 G A 8: 14,961,238 (GRCm38) E265K probably damaging Het
Cd53 A G 3: 106,768,826 (GRCm38) I75T probably damaging Het
Col26a1 A T 5: 136,754,339 (GRCm38) L235* probably null Het
Crem G T 18: 3,273,477 (GRCm38) Q60K probably damaging Het
Cyp2j8 T C 4: 96,470,650 (GRCm38) D344G probably damaging Het
Cyr61 T C 3: 145,648,700 (GRCm38) K152R probably damaging Het
Dchs1 T C 7: 105,755,806 (GRCm38) T2510A probably benign Het
Dnajc4 T C 19: 6,988,088 (GRCm38) Q215R possibly damaging Het
Espl1 A G 15: 102,315,800 (GRCm38) H1262R probably benign Het
Exoc2 G T 13: 30,911,196 (GRCm38) T239K probably damaging Het
Fzd6 A T 15: 39,031,386 (GRCm38) S316C probably damaging Het
Htra1 A G 7: 130,984,974 (GRCm38) K429R probably benign Het
Il1rapl2 C T X: 138,846,503 (GRCm38) T647I possibly damaging Het
Kcnn3 T A 3: 89,661,112 (GRCm38) probably benign Het
Kiz G A 2: 146,863,813 (GRCm38) V98I probably benign Het
Klk1b24 A T 7: 44,188,324 (GRCm38) probably benign Het
Lrrc30 T A 17: 67,631,862 (GRCm38) N241I probably damaging Het
Map2k4 A G 11: 65,696,310 (GRCm38) V288A probably damaging Het
Mefv T C 16: 3,713,577 (GRCm38) H459R probably damaging Het
Mettl21a G T 1: 64,608,054 (GRCm38) Q115K probably benign Het
Msra A G 14: 64,285,188 (GRCm38) probably benign Het
Myh8 G A 11: 67,305,710 (GRCm38) R1752H probably benign Het
Nrp1 T C 8: 128,425,799 (GRCm38) F163S possibly damaging Het
Ntng1 T A 3: 110,135,330 (GRCm38) Y60F probably damaging Het
Pax6 G T 2: 105,692,770 (GRCm38) R317L probably benign Het
Pcdh17 A G 14: 84,533,469 (GRCm38) E1129G probably benign Het
Phlpp2 C T 8: 109,913,618 (GRCm38) H472Y probably benign Het
Pip5k1c C A 10: 81,317,321 (GRCm38) probably null Het
Prkce A G 17: 86,168,914 (GRCm38) N108D probably benign Het
Prkdc T G 16: 15,714,282 (GRCm38) probably null Het
Ptprm T C 17: 66,920,048 (GRCm38) Y702C probably damaging Het
Rbbp8nl T C 2: 180,279,329 (GRCm38) T421A possibly damaging Het
Retnlg A T 16: 48,872,960 (GRCm38) L33F probably benign Het
Slc16a7 T A 10: 125,230,933 (GRCm38) Y279F probably damaging Het
Slc8a1 T C 17: 81,388,713 (GRCm38) Y964C probably damaging Het
Srrm1 G A 4: 135,325,104 (GRCm38) P658L unknown Het
Tmprss11b C T 5: 86,667,323 (GRCm38) probably null Het
Txnrd1 T G 10: 82,879,217 (GRCm38) W98G probably damaging Het
Ulk1 A T 5: 110,809,134 (GRCm38) I66N probably damaging Het
Ush2a A G 1: 188,822,696 (GRCm38) Y3557C probably damaging Het
Vmn2r57 T A 7: 41,428,226 (GRCm38) H172L probably benign Het
Zfp518a G A 19: 40,914,617 (GRCm38) G997R probably damaging Het
Zfp592 T A 7: 81,041,726 (GRCm38) C1218S probably benign Het
Other mutations in Sspo
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00333:Sspo APN 6 48,470,453 (GRCm38) missense probably benign 0.02
IGL00339:Sspo APN 6 48,483,746 (GRCm38) splice site probably benign
IGL00391:Sspo APN 6 48,497,386 (GRCm38) missense probably damaging 0.96
IGL00433:Sspo APN 6 48,490,036 (GRCm38) missense probably damaging 1.00
IGL00471:Sspo APN 6 48,498,213 (GRCm38) splice site probably benign
IGL00500:Sspo APN 6 48,497,421 (GRCm38) nonsense probably null
IGL00537:Sspo APN 6 48,498,213 (GRCm38) splice site probably benign
IGL00540:Sspo APN 6 48,498,213 (GRCm38) splice site probably benign
IGL01060:Sspo APN 6 48,449,479 (GRCm38) nonsense probably null
IGL01090:Sspo APN 6 48,490,125 (GRCm38) missense probably benign 0.08
IGL01125:Sspo APN 6 48,492,888 (GRCm38) missense probably damaging 1.00
IGL01447:Sspo APN 6 48,464,666 (GRCm38) splice site probably null
IGL01457:Sspo APN 6 48,498,343 (GRCm38) missense probably benign 0.00
IGL01481:Sspo APN 6 48,448,515 (GRCm38) missense probably benign 0.41
IGL01485:Sspo APN 6 48,478,731 (GRCm38) missense probably damaging 1.00
IGL01544:Sspo APN 6 48,491,019 (GRCm38) missense probably damaging 0.99
IGL01575:Sspo APN 6 48,459,042 (GRCm38) missense probably benign 0.01
IGL01589:Sspo APN 6 48,451,178 (GRCm38) missense probably damaging 1.00
IGL01601:Sspo APN 6 48,486,379 (GRCm38) missense probably benign 0.33
IGL01644:Sspo APN 6 48,452,502 (GRCm38) missense probably benign
IGL01659:Sspo APN 6 48,474,443 (GRCm38) missense probably damaging 1.00
IGL01801:Sspo APN 6 48,457,138 (GRCm38) missense probably damaging 1.00
IGL01872:Sspo APN 6 48,454,689 (GRCm38) missense probably damaging 0.99
IGL01874:Sspo APN 6 48,452,190 (GRCm38) missense probably damaging 1.00
IGL01936:Sspo APN 6 48,475,887 (GRCm38) missense probably damaging 1.00
IGL01941:Sspo APN 6 48,495,182 (GRCm38) missense probably benign 0.19
IGL01986:Sspo APN 6 48,483,303 (GRCm38) missense probably benign 0.05
IGL01987:Sspo APN 6 48,477,624 (GRCm38) splice site probably null
IGL02170:Sspo APN 6 48,467,983 (GRCm38) missense possibly damaging 0.76
IGL02192:Sspo APN 6 48,459,568 (GRCm38) missense possibly damaging 0.86
IGL02210:Sspo APN 6 48,500,492 (GRCm38) missense probably damaging 1.00
IGL02225:Sspo APN 6 48,484,334 (GRCm38) missense probably benign 0.09
IGL02280:Sspo APN 6 48,496,231 (GRCm38) missense probably damaging 1.00
IGL02303:Sspo APN 6 48,484,705 (GRCm38) missense possibly damaging 0.52
IGL02397:Sspo APN 6 48,461,638 (GRCm38) missense probably benign 0.35
IGL02451:Sspo APN 6 48,460,303 (GRCm38) splice site probably benign
IGL02519:Sspo APN 6 48,484,828 (GRCm38) missense probably damaging 1.00
IGL02549:Sspo APN 6 48,451,773 (GRCm38) missense possibly damaging 0.81
IGL02562:Sspo APN 6 48,490,122 (GRCm38) splice site probably null
IGL02673:Sspo APN 6 48,475,860 (GRCm38) missense probably damaging 1.00
IGL02673:Sspo APN 6 48,498,775 (GRCm38) critical splice donor site probably null
IGL02719:Sspo APN 6 48,482,667 (GRCm38) missense probably benign 0.39
IGL02793:Sspo APN 6 48,487,894 (GRCm38) splice site probably benign
IGL03003:Sspo APN 6 48,455,087 (GRCm38) missense probably damaging 0.98
IGL03056:Sspo APN 6 48,470,538 (GRCm38) missense probably benign 0.17
IGL03105:Sspo APN 6 48,473,658 (GRCm38) splice site probably benign
IGL03116:Sspo APN 6 48,494,101 (GRCm38) missense probably benign 0.32
IGL03163:Sspo APN 6 48,484,332 (GRCm38) missense probably benign 0.19
IGL03198:Sspo APN 6 48,477,582 (GRCm38) missense probably benign 0.31
IGL03365:Sspo APN 6 48,459,415 (GRCm38) missense possibly damaging 0.82
Barrier UTSW 6 48,495,212 (GRCm38) missense possibly damaging 0.58
R0312_sspo_280 UTSW 6 48,455,401 (GRCm38) missense possibly damaging 0.52
R3112_Sspo_731 UTSW 6 48,457,600 (GRCm38) missense probably damaging 1.00
R3498_Sspo_650 UTSW 6 48,467,980 (GRCm38) missense possibly damaging 0.58
R4180_Sspo_324 UTSW 6 48,498,395 (GRCm38) critical splice donor site probably null
spotsylvania UTSW 6 48,476,571 (GRCm38) nonsense probably null
ANU74:Sspo UTSW 6 48,460,959 (GRCm38) missense probably damaging 1.00
IGL02984:Sspo UTSW 6 48,495,155 (GRCm38) missense probably benign 0.33
IGL03052:Sspo UTSW 6 48,460,453 (GRCm38) missense probably damaging 1.00
IGL03134:Sspo UTSW 6 48,451,065 (GRCm38) missense probably benign 0.28
PIT4531001:Sspo UTSW 6 48,481,239 (GRCm38) missense probably benign
R0087:Sspo UTSW 6 48,477,785 (GRCm38) missense probably damaging 1.00
R0122:Sspo UTSW 6 48,473,976 (GRCm38) missense possibly damaging 0.95
R0129:Sspo UTSW 6 48,455,418 (GRCm38) missense probably benign 0.00
R0164:Sspo UTSW 6 48,494,194 (GRCm38) splice site probably benign
R0195:Sspo UTSW 6 48,486,636 (GRCm38) missense probably benign
R0200:Sspo UTSW 6 48,486,415 (GRCm38) missense probably null 0.01
R0201:Sspo UTSW 6 48,455,752 (GRCm38) missense possibly damaging 0.64
R0241:Sspo UTSW 6 48,461,495 (GRCm38) missense possibly damaging 0.82
R0241:Sspo UTSW 6 48,461,495 (GRCm38) missense possibly damaging 0.82
R0243:Sspo UTSW 6 48,493,186 (GRCm38) missense probably damaging 1.00
R0268:Sspo UTSW 6 48,465,555 (GRCm38) missense probably benign 0.26
R0312:Sspo UTSW 6 48,455,401 (GRCm38) missense possibly damaging 0.52
R0449:Sspo UTSW 6 48,466,740 (GRCm38) missense probably damaging 1.00
R0523:Sspo UTSW 6 48,451,860 (GRCm38) missense probably benign 0.20
R0576:Sspo UTSW 6 48,464,942 (GRCm38) splice site probably null
R0671:Sspo UTSW 6 48,490,391 (GRCm38) splice site probably benign
R0828:Sspo UTSW 6 48,498,734 (GRCm38) missense probably damaging 1.00
R0880:Sspo UTSW 6 48,475,935 (GRCm38) missense possibly damaging 0.69
R0903:Sspo UTSW 6 48,455,308 (GRCm38) critical splice acceptor site probably null
R1051:Sspo UTSW 6 48,491,455 (GRCm38) nonsense probably null
R1083:Sspo UTSW 6 48,470,999 (GRCm38) missense possibly damaging 0.91
R1109:Sspo UTSW 6 48,497,443 (GRCm38) missense probably damaging 1.00
R1118:Sspo UTSW 6 48,459,418 (GRCm38) missense probably damaging 0.97
R1256:Sspo UTSW 6 48,457,639 (GRCm38) missense probably damaging 1.00
R1342:Sspo UTSW 6 48,461,635 (GRCm38) missense probably benign 0.07
R1355:Sspo UTSW 6 48,448,626 (GRCm38) missense probably benign 0.41
R1370:Sspo UTSW 6 48,448,626 (GRCm38) missense probably benign 0.41
R1469:Sspo UTSW 6 48,490,982 (GRCm38) missense probably damaging 1.00
R1469:Sspo UTSW 6 48,490,982 (GRCm38) missense probably damaging 1.00
R1476:Sspo UTSW 6 48,463,400 (GRCm38) critical splice donor site probably null
R1566:Sspo UTSW 6 48,466,870 (GRCm38) critical splice donor site probably null
R1630:Sspo UTSW 6 48,457,724 (GRCm38) missense probably benign 0.01
R1686:Sspo UTSW 6 48,460,400 (GRCm38) missense probably benign 0.00
R1707:Sspo UTSW 6 48,477,877 (GRCm38) missense probably damaging 0.99
R1727:Sspo UTSW 6 48,494,848 (GRCm38) missense probably damaging 1.00
R1822:Sspo UTSW 6 48,492,886 (GRCm38) missense possibly damaging 0.75
R1831:Sspo UTSW 6 48,489,786 (GRCm38) missense probably damaging 1.00
R1835:Sspo UTSW 6 48,457,340 (GRCm38) missense probably damaging 0.97
R1862:Sspo UTSW 6 48,491,006 (GRCm38) missense probably damaging 0.98
R1878:Sspo UTSW 6 48,459,366 (GRCm38) missense possibly damaging 0.92
R1900:Sspo UTSW 6 48,459,350 (GRCm38) missense probably benign 0.22
R1945:Sspo UTSW 6 48,489,773 (GRCm38) missense possibly damaging 0.93
R1957:Sspo UTSW 6 48,478,273 (GRCm38) missense probably damaging 0.99
R1990:Sspo UTSW 6 48,451,050 (GRCm38) missense probably benign 0.00
R1996:Sspo UTSW 6 48,475,490 (GRCm38) missense possibly damaging 0.50
R2049:Sspo UTSW 6 48,463,531 (GRCm38) missense probably benign 0.36
R2049:Sspo UTSW 6 48,460,763 (GRCm38) splice site probably benign
R2064:Sspo UTSW 6 48,473,662 (GRCm38) missense probably damaging 0.99
R2072:Sspo UTSW 6 48,473,517 (GRCm38) missense probably benign 0.01
R2096:Sspo UTSW 6 48,461,674 (GRCm38) missense probably benign
R2106:Sspo UTSW 6 48,466,316 (GRCm38) missense possibly damaging 0.96
R2230:Sspo UTSW 6 48,500,503 (GRCm38) missense probably benign 0.11
R2230:Sspo UTSW 6 48,448,672 (GRCm38) missense probably damaging 0.97
R2232:Sspo UTSW 6 48,448,672 (GRCm38) missense probably damaging 0.97
R2351:Sspo UTSW 6 48,464,869 (GRCm38) missense probably damaging 1.00
R2423:Sspo UTSW 6 48,454,055 (GRCm38) missense probably benign 0.00
R2508:Sspo UTSW 6 48,464,364 (GRCm38) missense probably damaging 1.00
R3110:Sspo UTSW 6 48,457,600 (GRCm38) missense probably damaging 1.00
R3112:Sspo UTSW 6 48,457,600 (GRCm38) missense probably damaging 1.00
R3413:Sspo UTSW 6 48,480,697 (GRCm38) missense probably damaging 1.00
R3433:Sspo UTSW 6 48,475,951 (GRCm38) splice site probably null
R3498:Sspo UTSW 6 48,467,980 (GRCm38) missense possibly damaging 0.58
R3732:Sspo UTSW 6 48,449,930 (GRCm38) missense probably damaging 1.00
R3816:Sspo UTSW 6 48,481,103 (GRCm38) missense possibly damaging 0.77
R3818:Sspo UTSW 6 48,481,103 (GRCm38) missense possibly damaging 0.77
R3819:Sspo UTSW 6 48,481,103 (GRCm38) missense possibly damaging 0.77
R3838:Sspo UTSW 6 48,480,820 (GRCm38) missense probably damaging 1.00
R3850:Sspo UTSW 6 48,492,490 (GRCm38) missense probably damaging 1.00
R3880:Sspo UTSW 6 48,494,940 (GRCm38) missense probably benign 0.38
R3893:Sspo UTSW 6 48,476,571 (GRCm38) nonsense probably null
R4116:Sspo UTSW 6 48,456,994 (GRCm38) missense probably damaging 0.99
R4179:Sspo UTSW 6 48,498,395 (GRCm38) critical splice donor site probably null
R4180:Sspo UTSW 6 48,498,395 (GRCm38) critical splice donor site probably null
R4207:Sspo UTSW 6 48,478,293 (GRCm38) missense probably benign 0.00
R4210:Sspo UTSW 6 48,464,901 (GRCm38) missense probably benign 0.00
R4223:Sspo UTSW 6 48,451,157 (GRCm38) missense possibly damaging 0.54
R4224:Sspo UTSW 6 48,451,157 (GRCm38) missense possibly damaging 0.54
R4225:Sspo UTSW 6 48,451,157 (GRCm38) missense possibly damaging 0.54
R4229:Sspo UTSW 6 48,490,934 (GRCm38) missense probably benign 0.00
R4230:Sspo UTSW 6 48,490,934 (GRCm38) missense probably benign 0.00
R4363:Sspo UTSW 6 48,498,731 (GRCm38) missense probably damaging 1.00
R4370:Sspo UTSW 6 48,466,348 (GRCm38) missense probably null 0.14
R4407:Sspo UTSW 6 48,460,520 (GRCm38) missense probably damaging 1.00
R4438:Sspo UTSW 6 48,487,353 (GRCm38) missense probably damaging 1.00
R4454:Sspo UTSW 6 48,487,225 (GRCm38) missense probably benign 0.05
R4455:Sspo UTSW 6 48,465,516 (GRCm38) missense probably damaging 1.00
R4561:Sspo UTSW 6 48,475,534 (GRCm38) splice site probably null
R4574:Sspo UTSW 6 48,465,523 (GRCm38) missense probably damaging 1.00
R4578:Sspo UTSW 6 48,463,373 (GRCm38) missense possibly damaging 0.58
R4653:Sspo UTSW 6 48,478,646 (GRCm38) missense probably damaging 1.00
R4656:Sspo UTSW 6 48,454,076 (GRCm38) missense possibly damaging 0.65
R4659:Sspo UTSW 6 48,484,213 (GRCm38) missense probably damaging 1.00
R4664:Sspo UTSW 6 48,473,534 (GRCm38) missense possibly damaging 0.82
R4685:Sspo UTSW 6 48,492,894 (GRCm38) missense probably damaging 0.98
R4692:Sspo UTSW 6 48,482,687 (GRCm38) missense probably damaging 1.00
R4703:Sspo UTSW 6 48,500,453 (GRCm38) missense probably damaging 1.00
R4704:Sspo UTSW 6 48,498,704 (GRCm38) missense probably damaging 1.00
R4738:Sspo UTSW 6 48,478,396 (GRCm38) missense possibly damaging 0.78
R4766:Sspo UTSW 6 48,470,580 (GRCm38) missense probably benign 0.04
R4771:Sspo UTSW 6 48,460,879 (GRCm38) missense probably damaging 1.00
R4790:Sspo UTSW 6 48,460,771 (GRCm38) missense probably benign 0.04
R4792:Sspo UTSW 6 48,461,585 (GRCm38) missense probably benign 0.00
R4808:Sspo UTSW 6 48,451,161 (GRCm38) missense probably damaging 1.00
R4812:Sspo UTSW 6 48,490,510 (GRCm38) missense probably benign 0.00
R4883:Sspo UTSW 6 48,460,822 (GRCm38) missense probably benign 0.00
R4906:Sspo UTSW 6 48,465,730 (GRCm38) critical splice acceptor site probably null
R4934:Sspo UTSW 6 48,465,552 (GRCm38) missense probably damaging 1.00
R4945:Sspo UTSW 6 48,467,087 (GRCm38) splice site probably null
R4967:Sspo UTSW 6 48,464,605 (GRCm38) missense probably damaging 0.97
R5016:Sspo UTSW 6 48,452,280 (GRCm38) nonsense probably null
R5018:Sspo UTSW 6 48,455,700 (GRCm38) missense probably damaging 1.00
R5034:Sspo UTSW 6 48,480,823 (GRCm38) missense possibly damaging 0.93
R5044:Sspo UTSW 6 48,466,955 (GRCm38) critical splice acceptor site probably null
R5055:Sspo UTSW 6 48,464,795 (GRCm38) missense probably damaging 1.00
R5087:Sspo UTSW 6 48,488,471 (GRCm38) missense possibly damaging 0.51
R5155:Sspo UTSW 6 48,460,474 (GRCm38) missense probably benign 0.03
R5223:Sspo UTSW 6 48,478,324 (GRCm38) missense probably damaging 1.00
R5249:Sspo UTSW 6 48,493,310 (GRCm38) missense probably damaging 0.98
R5257:Sspo UTSW 6 48,476,494 (GRCm38) missense probably damaging 1.00
R5258:Sspo UTSW 6 48,476,494 (GRCm38) missense probably damaging 1.00
R5276:Sspo UTSW 6 48,490,467 (GRCm38) missense probably damaging 1.00
R5307:Sspo UTSW 6 48,454,850 (GRCm38) missense probably damaging 0.99
R5341:Sspo UTSW 6 48,459,615 (GRCm38) missense probably damaging 1.00
R5361:Sspo UTSW 6 48,466,313 (GRCm38) missense probably benign 0.02
R5385:Sspo UTSW 6 48,462,253 (GRCm38) missense probably benign 0.18
R5394:Sspo UTSW 6 48,495,260 (GRCm38) missense possibly damaging 0.52
R5477:Sspo UTSW 6 48,498,393 (GRCm38) missense possibly damaging 0.60
R5490:Sspo UTSW 6 48,493,280 (GRCm38) missense probably benign 0.33
R5512:Sspo UTSW 6 48,455,671 (GRCm38) missense probably damaging 0.97
R5518:Sspo UTSW 6 48,496,654 (GRCm38) missense possibly damaging 0.92
R5530:Sspo UTSW 6 48,465,583 (GRCm38) missense probably damaging 0.97
R5538:Sspo UTSW 6 48,452,178 (GRCm38) missense probably damaging 0.99
R5590:Sspo UTSW 6 48,474,491 (GRCm38) missense probably damaging 1.00
R5613:Sspo UTSW 6 48,455,044 (GRCm38) missense possibly damaging 0.79
R5638:Sspo UTSW 6 48,492,891 (GRCm38) missense possibly damaging 0.86
R5809:Sspo UTSW 6 48,460,045 (GRCm38) missense possibly damaging 0.59
R5810:Sspo UTSW 6 48,483,898 (GRCm38) missense probably benign 0.02
R5814:Sspo UTSW 6 48,451,884 (GRCm38) missense probably damaging 1.00
R5915:Sspo UTSW 6 48,491,484 (GRCm38) missense possibly damaging 0.83
R5915:Sspo UTSW 6 48,464,596 (GRCm38) missense probably benign 0.00
R5979:Sspo UTSW 6 48,463,693 (GRCm38) missense probably benign 0.20
R5996:Sspo UTSW 6 48,494,176 (GRCm38) missense possibly damaging 0.87
R6012:Sspo UTSW 6 48,451,371 (GRCm38) missense probably benign 0.00
R6025:Sspo UTSW 6 48,486,786 (GRCm38) missense possibly damaging 0.83
R6120:Sspo UTSW 6 48,465,576 (GRCm38) missense probably damaging 1.00
R6150:Sspo UTSW 6 48,486,379 (GRCm38) missense probably benign 0.33
R6221:Sspo UTSW 6 48,463,705 (GRCm38) missense probably damaging 1.00
R6261:Sspo UTSW 6 48,462,191 (GRCm38) missense possibly damaging 0.75
R6312:Sspo UTSW 6 48,457,366 (GRCm38) critical splice donor site probably null
R6372:Sspo UTSW 6 48,472,541 (GRCm38) missense probably damaging 1.00
R6456:Sspo UTSW 6 48,451,806 (GRCm38) missense probably benign 0.08
R6497:Sspo UTSW 6 48,495,208 (GRCm38) missense possibly damaging 0.71
R6501:Sspo UTSW 6 48,495,212 (GRCm38) missense possibly damaging 0.58
R6617:Sspo UTSW 6 48,491,046 (GRCm38) missense possibly damaging 0.93
R6825:Sspo UTSW 6 48,465,525 (GRCm38) missense probably benign 0.04
R6831:Sspo UTSW 6 48,484,833 (GRCm38) missense possibly damaging 0.68
R6861:Sspo UTSW 6 48,487,955 (GRCm38) missense probably benign 0.15
R6961:Sspo UTSW 6 48,463,877 (GRCm38) missense probably benign 0.05
R6967:Sspo UTSW 6 48,489,794 (GRCm38) missense probably benign 0.21
R7016:Sspo UTSW 6 48,449,164 (GRCm38) missense probably damaging 1.00
R7035:Sspo UTSW 6 48,449,213 (GRCm38) splice site probably null
R7058:Sspo UTSW 6 48,448,582 (GRCm38) missense probably damaging 1.00
R7072:Sspo UTSW 6 48,454,979 (GRCm38) missense probably damaging 1.00
R7078:Sspo UTSW 6 48,460,379 (GRCm38) missense probably damaging 1.00
R7082:Sspo UTSW 6 48,478,609 (GRCm38) critical splice acceptor site probably null
R7120:Sspo UTSW 6 48,465,571 (GRCm38) missense probably benign 0.05
R7127:Sspo UTSW 6 48,449,512 (GRCm38) missense probably benign 0.02
R7146:Sspo UTSW 6 48,501,095 (GRCm38) missense probably benign 0.15
R7220:Sspo UTSW 6 48,476,606 (GRCm38) nonsense probably null
R7242:Sspo UTSW 6 48,473,952 (GRCm38) missense probably benign
R7261:Sspo UTSW 6 48,450,077 (GRCm38) missense possibly damaging 0.52
R7313:Sspo UTSW 6 48,473,456 (GRCm38) missense probably benign 0.04
R7313:Sspo UTSW 6 48,454,828 (GRCm38) missense probably damaging 1.00
R7323:Sspo UTSW 6 48,461,647 (GRCm38) missense possibly damaging 0.93
R7330:Sspo UTSW 6 48,475,462 (GRCm38) missense probably benign 0.00
R7351:Sspo UTSW 6 48,464,921 (GRCm38) missense possibly damaging 0.89
R7467:Sspo UTSW 6 48,486,303 (GRCm38) missense probably damaging 1.00
R7475:Sspo UTSW 6 48,455,860 (GRCm38) missense probably benign 0.37
R7489:Sspo UTSW 6 48,473,713 (GRCm38) missense probably damaging 0.99
R7508:Sspo UTSW 6 48,466,699 (GRCm38) missense probably damaging 1.00
R7515:Sspo UTSW 6 48,493,886 (GRCm38) missense probably damaging 1.00
R7564:Sspo UTSW 6 48,449,500 (GRCm38) missense probably benign 0.04
R7607:Sspo UTSW 6 48,489,727 (GRCm38) missense probably damaging 1.00
R7620:Sspo UTSW 6 48,467,086 (GRCm38) critical splice donor site probably null
R7667:Sspo UTSW 6 48,475,371 (GRCm38) nonsense probably null
R7691:Sspo UTSW 6 48,484,229 (GRCm38) missense probably benign 0.12
R7707:Sspo UTSW 6 48,461,527 (GRCm38) missense probably benign 0.01
R7723:Sspo UTSW 6 48,464,638 (GRCm38) missense probably damaging 0.99
R7748:Sspo UTSW 6 48,449,465 (GRCm38) nonsense probably null
R7767:Sspo UTSW 6 48,451,382 (GRCm38) missense probably damaging 0.96
R7792:Sspo UTSW 6 48,454,690 (GRCm38) missense probably damaging 0.98
R7878:Sspo UTSW 6 48,492,526 (GRCm38) missense probably damaging 1.00
R7893:Sspo UTSW 6 48,463,310 (GRCm38) missense probably benign 0.02
R7942:Sspo UTSW 6 48,488,500 (GRCm38) splice site probably null
R7952:Sspo UTSW 6 48,487,329 (GRCm38) missense probably damaging 1.00
R7981:Sspo UTSW 6 48,468,494 (GRCm38) missense probably benign
R7995:Sspo UTSW 6 48,492,889 (GRCm38) missense probably damaging 1.00
R8088:Sspo UTSW 6 48,457,613 (GRCm38) missense probably damaging 1.00
R8129:Sspo UTSW 6 48,467,025 (GRCm38) missense possibly damaging 0.79
R8145:Sspo UTSW 6 48,467,749 (GRCm38) missense possibly damaging 0.49
R8202:Sspo UTSW 6 48,457,600 (GRCm38) missense probably damaging 1.00
R8211:Sspo UTSW 6 48,492,609 (GRCm38) critical splice donor site probably null
R8240:Sspo UTSW 6 48,483,502 (GRCm38) missense possibly damaging 0.84
R8252:Sspo UTSW 6 48,485,452 (GRCm38) missense probably damaging 0.99
R8270:Sspo UTSW 6 48,449,963 (GRCm38) missense probably benign
R8272:Sspo UTSW 6 48,448,519 (GRCm38) missense probably benign 0.03
R8316:Sspo UTSW 6 48,482,688 (GRCm38) missense probably damaging 1.00
R8384:Sspo UTSW 6 48,482,664 (GRCm38) missense probably damaging 1.00
R8390:Sspo UTSW 6 48,467,962 (GRCm38) missense probably benign 0.00
R8770:Sspo UTSW 6 48,474,272 (GRCm38) missense probably null 1.00
R8827:Sspo UTSW 6 48,457,672 (GRCm38) missense possibly damaging 0.59
R8882:Sspo UTSW 6 48,475,456 (GRCm38) missense probably damaging 1.00
R8886:Sspo UTSW 6 48,481,267 (GRCm38) missense possibly damaging 0.92
R8946:Sspo UTSW 6 48,457,137 (GRCm38) missense probably damaging 1.00
R8947:Sspo UTSW 6 48,448,570 (GRCm38) missense probably damaging 1.00
R9028:Sspo UTSW 6 48,496,153 (GRCm38) missense probably benign 0.38
R9043:Sspo UTSW 6 48,493,280 (GRCm38) missense probably benign 0.07
R9056:Sspo UTSW 6 48,473,674 (GRCm38) missense probably damaging 0.97
R9071:Sspo UTSW 6 48,457,048 (GRCm38) missense probably benign 0.00
R9133:Sspo UTSW 6 48,457,813 (GRCm38) missense possibly damaging 0.81
R9187:Sspo UTSW 6 48,495,289 (GRCm38) missense probably damaging 1.00
R9205:Sspo UTSW 6 48,455,872 (GRCm38) missense probably benign 0.03
R9213:Sspo UTSW 6 48,463,935 (GRCm38) missense possibly damaging 0.91
R9214:Sspo UTSW 6 48,463,935 (GRCm38) missense possibly damaging 0.91
R9215:Sspo UTSW 6 48,463,935 (GRCm38) missense possibly damaging 0.91
R9235:Sspo UTSW 6 48,489,784 (GRCm38) missense probably damaging 1.00
R9254:Sspo UTSW 6 48,487,994 (GRCm38) missense probably damaging 1.00
R9291:Sspo UTSW 6 48,496,396 (GRCm38) missense probably damaging 1.00
R9312:Sspo UTSW 6 48,468,462 (GRCm38) missense probably benign 0.00
R9357:Sspo UTSW 6 48,467,055 (GRCm38) missense possibly damaging 0.77
R9480:Sspo UTSW 6 48,493,886 (GRCm38) missense probably damaging 1.00
R9586:Sspo UTSW 6 48,481,105 (GRCm38) missense probably benign 0.03
R9660:Sspo UTSW 6 48,455,773 (GRCm38) missense probably damaging 1.00
R9661:Sspo UTSW 6 48,478,338 (GRCm38) nonsense probably null
R9728:Sspo UTSW 6 48,455,773 (GRCm38) missense probably damaging 1.00
R9776:Sspo UTSW 6 48,462,335 (GRCm38) missense probably benign 0.00
RF009:Sspo UTSW 6 48,459,985 (GRCm38) nonsense probably null
X0060:Sspo UTSW 6 48,480,794 (GRCm38) missense probably damaging 1.00
X0060:Sspo UTSW 6 48,466,294 (GRCm38) missense probably damaging 1.00
X0063:Sspo UTSW 6 48,497,422 (GRCm38) missense probably damaging 0.96
X0065:Sspo UTSW 6 48,461,684 (GRCm38) missense probably benign 0.00
Z1176:Sspo UTSW 6 48,481,293 (GRCm38) missense probably damaging 1.00
Z1177:Sspo UTSW 6 48,490,890 (GRCm38) missense probably damaging 1.00
Z1177:Sspo UTSW 6 48,490,548 (GRCm38) nonsense probably null
Z1177:Sspo UTSW 6 48,473,435 (GRCm38) missense probably damaging 0.99
Z1177:Sspo UTSW 6 48,470,984 (GRCm38) missense probably benign 0.16
Z1177:Sspo UTSW 6 48,464,816 (GRCm38) missense possibly damaging 0.72
Z1177:Sspo UTSW 6 48,457,026 (GRCm38) missense probably benign 0.31
Z1186:Sspo UTSW 6 48,468,507 (GRCm38) missense probably benign
Posted On 2015-04-16