Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02500:Dchs1'

296013

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Dchs1

Ensembl Gene

ENSMUSG00000036862

Gene Name

dachsous cadherin related 1

Synonyms

3110041P15Rik, C130033F22Rik

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

IGL02500

Quality Score

Status

Chromosome

Chromosomal Location

105752990-105787654 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 105755806 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Alanine at position 2510 (T2510A)

Ref Sequence

ENSEMBL: ENSMUSP00000077574 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000033184] [ENSMUST00000078482] [ENSMUST00000210066]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000033184

SMART Domains

Protein: ENSMUSP00000033184
Gene: ENSMUSG00000030894

Domain	Start	End	E-Value	Type
low complexity region	2	17	N/A	INTRINSIC
Pro-kuma_activ	32	176	4.53e-50	SMART
low complexity region	177	189	N/A	INTRINSIC
Pfam:Peptidase_S8	251	492	1.1e-9	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000078482
AA Change: T2510A

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000077574
Gene: ENSMUSG00000036862
AA Change: T2510A

Domain	Start	End	E-Value	Type
signal peptide	1	36	N/A	INTRINSIC
CA	58	135	5.2e-11	SMART
CA	159	247	6.1e-17	SMART
CA	271	354	2.6e-30	SMART
CA	382	464	7.8e-26	SMART
CA	489	570	1.2e-34	SMART
CA	594	677	1.9e-27	SMART
CA	701	782	5.3e-11	SMART
CA	806	886	1e-12	SMART
CA	910	990	3.3e-14	SMART
CA	1016	1097	3.6e-18	SMART
CA	1121	1203	3.1e-34	SMART
CA	1233	1307	8.8e-16	SMART
low complexity region	1323	1335	N/A	INTRINSIC
CA	1344	1427	9.9e-9	SMART
CA	1451	1537	1.5e-23	SMART
CA	1560	1640	7.2e-32	SMART
CA	1664	1742	1.8e-31	SMART
CA	1765	1846	7.8e-30	SMART
CA	1870	1951	3.7e-26	SMART
low complexity region	1957	1965	N/A	INTRINSIC
CA	1979	2059	1.1e-6	SMART
CA	2083	2162	2.7e-18	SMART
CA	2186	2268	2.2e-26	SMART
CA	2291	2367	1e-18	SMART
CA	2391	2473	1.8e-23	SMART
CA	2497	2593	3.5e-21	SMART
CA	2617	2697	1.2e-25	SMART
CA	2721	2804	1.9e-18	SMART
CA	2828	2919	3e-3	SMART
transmembrane domain	2932	2954	N/A	INTRINSIC
low complexity region	3001	3017	N/A	INTRINSIC
low complexity region	3046	3055	N/A	INTRINSIC
low complexity region	3088	3097	N/A	INTRINSIC
low complexity region	3185	3196	N/A	INTRINSIC
low complexity region	3237	3259	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000140959

Predicted Effect

probably benign
Transcript: ENSMUST00000210066

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000210395

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000210730

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000210840

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000211204

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000211226

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000211560

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000211659

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is a member of the cadherin superfamily whose members encode calcium-dependent cell-cell adhesion molecules. The encoded protein has a signal peptide, 27 cadherin repeat domains and a unique cytoplasmic region. This particular cadherin family member is expressed in fibroblasts but not in melanocytes or keratinocytes. The cell-cell adhesion of fibroblasts is thought to be necessary for wound healing. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit postnatal lethality, growth retardation, small lungs, abnormal cochlea morphology, abnormal kidney morphology, cardiovascular abnormalities and skeletal abnormalities. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 45 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcc4	A	T	14: 118,618,926 (GRCm38)	I409N	possibly damaging	Het
Aoc3	T	A	11: 101,337,389 (GRCm38)	L674*	probably null	Het
Arhgef10	G	A	8: 14,961,238 (GRCm38)	E265K	probably damaging	Het
Cd53	A	G	3: 106,768,826 (GRCm38)	I75T	probably damaging	Het
Col26a1	A	T	5: 136,754,339 (GRCm38)	L235*	probably null	Het
Crem	G	T	18: 3,273,477 (GRCm38)	Q60K	probably damaging	Het
Cyp2j8	T	C	4: 96,470,650 (GRCm38)	D344G	probably damaging	Het
Cyr61	T	C	3: 145,648,700 (GRCm38)	K152R	probably damaging	Het
Dnajc4	T	C	19: 6,988,088 (GRCm38)	Q215R	possibly damaging	Het
Espl1	A	G	15: 102,315,800 (GRCm38)	H1262R	probably benign	Het
Exoc2	G	T	13: 30,911,196 (GRCm38)	T239K	probably damaging	Het
Fzd6	A	T	15: 39,031,386 (GRCm38)	S316C	probably damaging	Het
Htra1	A	G	7: 130,984,974 (GRCm38)	K429R	probably benign	Het
Il1rapl2	C	T	X: 138,846,503 (GRCm38)	T647I	possibly damaging	Het
Kcnn3	T	A	3: 89,661,112 (GRCm38)		probably benign	Het
Kiz	G	A	2: 146,863,813 (GRCm38)	V98I	probably benign	Het
Klk1b24	A	T	7: 44,188,324 (GRCm38)		probably benign	Het
Lrrc30	T	A	17: 67,631,862 (GRCm38)	N241I	probably damaging	Het
Map2k4	A	G	11: 65,696,310 (GRCm38)	V288A	probably damaging	Het
Mefv	T	C	16: 3,713,577 (GRCm38)	H459R	probably damaging	Het
Mettl21a	G	T	1: 64,608,054 (GRCm38)	Q115K	probably benign	Het
Msra	A	G	14: 64,285,188 (GRCm38)		probably benign	Het
Myh8	G	A	11: 67,305,710 (GRCm38)	R1752H	probably benign	Het
Nrp1	T	C	8: 128,425,799 (GRCm38)	F163S	possibly damaging	Het
Ntng1	T	A	3: 110,135,330 (GRCm38)	Y60F	probably damaging	Het
Pax6	G	T	2: 105,692,770 (GRCm38)	R317L	probably benign	Het
Pcdh17	A	G	14: 84,533,469 (GRCm38)	E1129G	probably benign	Het
Phlpp2	C	T	8: 109,913,618 (GRCm38)	H472Y	probably benign	Het
Pip5k1c	C	A	10: 81,317,321 (GRCm38)		probably null	Het
Prkce	A	G	17: 86,168,914 (GRCm38)	N108D	probably benign	Het
Prkdc	T	G	16: 15,714,282 (GRCm38)		probably null	Het
Ptprm	T	C	17: 66,920,048 (GRCm38)	Y702C	probably damaging	Het
Rbbp8nl	T	C	2: 180,279,329 (GRCm38)	T421A	possibly damaging	Het
Retnlg	A	T	16: 48,872,960 (GRCm38)	L33F	probably benign	Het
Slc16a7	T	A	10: 125,230,933 (GRCm38)	Y279F	probably damaging	Het
Slc8a1	T	C	17: 81,388,713 (GRCm38)	Y964C	probably damaging	Het
Srrm1	G	A	4: 135,325,104 (GRCm38)	P658L	unknown	Het
Sspo	C	A	6: 48,478,379 (GRCm38)	C3047*	probably null	Het
Tmprss11b	C	T	5: 86,667,323 (GRCm38)		probably null	Het
Txnrd1	T	G	10: 82,879,217 (GRCm38)	W98G	probably damaging	Het
Ulk1	A	T	5: 110,809,134 (GRCm38)	I66N	probably damaging	Het
Ush2a	A	G	1: 188,822,696 (GRCm38)	Y3557C	probably damaging	Het
Vmn2r57	T	A	7: 41,428,226 (GRCm38)	H172L	probably benign	Het
Zfp518a	G	A	19: 40,914,617 (GRCm38)	G997R	probably damaging	Het
Zfp592	T	A	7: 81,041,726 (GRCm38)	C1218S	probably benign	Het

Other mutations in Dchs1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00235:Dchs1	APN	7	105,758,743 (GRCm38)	missense	probably damaging	1.00
IGL00422:Dchs1	APN	7	105,758,029 (GRCm38)	missense	possibly damaging	0.88
IGL00427:Dchs1	APN	7	105,758,424 (GRCm38)	missense	probably damaging	0.98
IGL00469:Dchs1	APN	7	105,755,261 (GRCm38)	missense	probably damaging	1.00
IGL00470:Dchs1	APN	7	105,758,207 (GRCm38)	missense	probably damaging	1.00
IGL00534:Dchs1	APN	7	105,757,943 (GRCm38)	missense	probably benign
IGL01292:Dchs1	APN	7	105,760,891 (GRCm38)	missense	probably damaging	0.98
IGL01380:Dchs1	APN	7	105,762,211 (GRCm38)	missense	probably damaging	1.00
IGL01396:Dchs1	APN	7	105,772,283 (GRCm38)	missense	probably damaging	1.00
IGL01448:Dchs1	APN	7	105,771,927 (GRCm38)	missense	probably damaging	0.98
IGL01759:Dchs1	APN	7	105,755,302 (GRCm38)	missense	probably benign	0.00
IGL01829:Dchs1	APN	7	105,755,397 (GRCm38)	missense	probably damaging	0.99
IGL01946:Dchs1	APN	7	105,759,105 (GRCm38)	missense	probably damaging	1.00
IGL01955:Dchs1	APN	7	105,757,591 (GRCm38)	missense	probably benign	0.00
IGL02012:Dchs1	APN	7	105,764,297 (GRCm38)	missense	probably damaging	0.98
IGL02222:Dchs1	APN	7	105,764,887 (GRCm38)	missense	probably damaging	1.00
IGL02261:Dchs1	APN	7	105,772,569 (GRCm38)	missense	probably damaging	1.00
IGL02365:Dchs1	APN	7	105,755,188 (GRCm38)	missense	probably benign	0.22
IGL02430:Dchs1	APN	7	105,771,971 (GRCm38)	missense	probably benign	0.34
IGL02741:Dchs1	APN	7	105,757,323 (GRCm38)	missense	probably damaging	1.00
IGL02890:Dchs1	APN	7	105,756,491 (GRCm38)	missense	probably damaging	1.00
IGL03213:Dchs1	APN	7	105,755,072 (GRCm38)	missense	probably damaging	1.00
G1patch:Dchs1	UTSW	7	105,758,793 (GRCm38)	missense	probably damaging	0.99
P0026:Dchs1	UTSW	7	105,758,405 (GRCm38)	missense	probably damaging	0.99
PIT4377001:Dchs1	UTSW	7	105,757,588 (GRCm38)	missense	probably damaging	1.00
PIT4791001:Dchs1	UTSW	7	105,758,971 (GRCm38)	missense	probably damaging	1.00
R0013:Dchs1	UTSW	7	105,755,836 (GRCm38)	missense	possibly damaging	0.90
R0090:Dchs1	UTSW	7	105,755,932 (GRCm38)	missense	probably benign	0.18
R0091:Dchs1	UTSW	7	105,766,094 (GRCm38)	splice site	probably benign
R0193:Dchs1	UTSW	7	105,764,983 (GRCm38)	missense	probably benign	0.40
R0395:Dchs1	UTSW	7	105,758,538 (GRCm38)	missense	probably damaging	1.00
R0448:Dchs1	UTSW	7	105,765,927 (GRCm38)	missense	probably benign	0.00
R0480:Dchs1	UTSW	7	105,771,489 (GRCm38)	missense	probably benign	0.14
R0485:Dchs1	UTSW	7	105,772,727 (GRCm38)	missense	probably benign	0.00
R0566:Dchs1	UTSW	7	105,759,195 (GRCm38)	missense	probably benign	0.00
R0571:Dchs1	UTSW	7	105,771,996 (GRCm38)	missense	probably damaging	1.00
R0573:Dchs1	UTSW	7	105,758,778 (GRCm38)	missense	probably damaging	0.98
R0577:Dchs1	UTSW	7	105,764,255 (GRCm38)	missense	possibly damaging	0.78
R0622:Dchs1	UTSW	7	105,763,449 (GRCm38)	missense	probably damaging	1.00
R0654:Dchs1	UTSW	7	105,772,349 (GRCm38)	missense	probably damaging	1.00
R0677:Dchs1	UTSW	7	105,764,984 (GRCm38)	missense	probably damaging	1.00
R1171:Dchs1	UTSW	7	105,757,714 (GRCm38)	missense	probably benign
R1241:Dchs1	UTSW	7	105,758,178 (GRCm38)	missense	probably damaging	1.00
R1389:Dchs1	UTSW	7	105,755,571 (GRCm38)	missense	probably benign	0.40
R1427:Dchs1	UTSW	7	105,766,191 (GRCm38)	missense	probably benign	0.06
R1458:Dchs1	UTSW	7	105,755,244 (GRCm38)	missense	probably damaging	1.00
R1513:Dchs1	UTSW	7	105,772,071 (GRCm38)	nonsense	probably null
R1524:Dchs1	UTSW	7	105,764,525 (GRCm38)	missense	probably damaging	1.00
R1525:Dchs1	UTSW	7	105,758,931 (GRCm38)	missense	probably damaging	1.00
R1534:Dchs1	UTSW	7	105,772,040 (GRCm38)	missense	probably damaging	0.98
R1567:Dchs1	UTSW	7	105,771,861 (GRCm38)	missense	probably benign	0.01
R1577:Dchs1	UTSW	7	105,765,955 (GRCm38)	missense	probably damaging	1.00
R1603:Dchs1	UTSW	7	105,762,770 (GRCm38)	missense	probably benign	0.24
R1676:Dchs1	UTSW	7	105,754,921 (GRCm38)	missense	probably benign	0.40
R1794:Dchs1	UTSW	7	105,771,720 (GRCm38)	missense	probably benign	0.02
R1826:Dchs1	UTSW	7	105,757,627 (GRCm38)	missense	probably damaging	1.00
R1892:Dchs1	UTSW	7	105,764,156 (GRCm38)	missense	probably benign	0.00
R1924:Dchs1	UTSW	7	105,772,280 (GRCm38)	missense	possibly damaging	0.81
R1932:Dchs1	UTSW	7	105,765,902 (GRCm38)	missense	probably damaging	1.00
R1962:Dchs1	UTSW	7	105,764,201 (GRCm38)	missense	probably damaging	1.00
R1985:Dchs1	UTSW	7	105,772,398 (GRCm38)	missense	possibly damaging	0.72
R1993:Dchs1	UTSW	7	105,762,548 (GRCm38)	missense	probably benign	0.00
R2007:Dchs1	UTSW	7	105,755,325 (GRCm38)	missense	probably damaging	1.00
R2316:Dchs1	UTSW	7	105,764,204 (GRCm38)	missense	possibly damaging	0.71
R2351:Dchs1	UTSW	7	105,754,094 (GRCm38)	missense	probably benign
R2474:Dchs1	UTSW	7	105,772,838 (GRCm38)	missense	probably damaging	1.00
R2474:Dchs1	UTSW	7	105,755,074 (GRCm38)	missense	probably benign	0.37
R3429:Dchs1	UTSW	7	105,756,504 (GRCm38)	missense	possibly damaging	0.85
R3430:Dchs1	UTSW	7	105,756,504 (GRCm38)	missense	possibly damaging	0.85
R3737:Dchs1	UTSW	7	105,762,316 (GRCm38)	missense	possibly damaging	0.88
R3767:Dchs1	UTSW	7	105,757,085 (GRCm38)	missense	possibly damaging	0.67
R3874:Dchs1	UTSW	7	105,761,635 (GRCm38)	missense	probably damaging	1.00
R3883:Dchs1	UTSW	7	105,762,563 (GRCm38)	missense	probably damaging	1.00
R4105:Dchs1	UTSW	7	105,765,140 (GRCm38)	missense	probably damaging	1.00
R4209:Dchs1	UTSW	7	105,766,190 (GRCm38)	missense	probably damaging	0.99
R4329:Dchs1	UTSW	7	105,753,759 (GRCm38)	missense	probably damaging	1.00
R4516:Dchs1	UTSW	7	105,754,852 (GRCm38)	missense	probably damaging	1.00
R4579:Dchs1	UTSW	7	105,758,973 (GRCm38)	missense	probably benign
R4579:Dchs1	UTSW	7	105,754,765 (GRCm38)	missense	probably damaging	1.00
R4588:Dchs1	UTSW	7	105,756,041 (GRCm38)	missense	probably benign
R4613:Dchs1	UTSW	7	105,772,724 (GRCm38)	missense	probably damaging	1.00
R4632:Dchs1	UTSW	7	105,754,355 (GRCm38)	missense	probably benign	0.02
R4696:Dchs1	UTSW	7	105,764,627 (GRCm38)	missense	probably damaging	1.00
R4725:Dchs1	UTSW	7	105,765,552 (GRCm38)	missense	probably damaging	1.00
R4725:Dchs1	UTSW	7	105,755,253 (GRCm38)	missense	probably damaging	0.98
R4738:Dchs1	UTSW	7	105,758,673 (GRCm38)	missense	probably damaging	0.96
R4768:Dchs1	UTSW	7	105,771,620 (GRCm38)	missense	possibly damaging	0.96
R4784:Dchs1	UTSW	7	105,765,926 (GRCm38)	missense	probably damaging	1.00
R4864:Dchs1	UTSW	7	105,755,253 (GRCm38)	missense	probably damaging	0.98
R4880:Dchs1	UTSW	7	105,755,730 (GRCm38)	missense	probably benign	0.00
R4909:Dchs1	UTSW	7	105,766,255 (GRCm38)	missense	probably damaging	1.00
R5102:Dchs1	UTSW	7	105,772,177 (GRCm38)	missense	probably benign	0.09
R5109:Dchs1	UTSW	7	105,765,014 (GRCm38)	missense	probably benign
R5126:Dchs1	UTSW	7	105,753,517 (GRCm38)	missense	probably damaging	1.00
R5149:Dchs1	UTSW	7	105,755,658 (GRCm38)	missense	probably damaging	0.98
R5330:Dchs1	UTSW	7	105,754,602 (GRCm38)	missense	probably damaging	1.00
R5384:Dchs1	UTSW	7	105,772,055 (GRCm38)	missense	probably damaging	1.00
R5384:Dchs1	UTSW	7	105,758,029 (GRCm38)	missense	probably damaging	1.00
R5386:Dchs1	UTSW	7	105,758,029 (GRCm38)	missense	probably damaging	1.00
R5622:Dchs1	UTSW	7	105,755,293 (GRCm38)	missense	probably benign	0.11
R5623:Dchs1	UTSW	7	105,772,769 (GRCm38)	missense	probably damaging	1.00
R5708:Dchs1	UTSW	7	105,772,809 (GRCm38)	missense	probably damaging	1.00
R5718:Dchs1	UTSW	7	105,755,748 (GRCm38)	missense	probably benign	0.01
R5743:Dchs1	UTSW	7	105,771,596 (GRCm38)	missense	probably benign
R5759:Dchs1	UTSW	7	105,764,176 (GRCm38)	missense	probably damaging	0.99
R5772:Dchs1	UTSW	7	105,773,040 (GRCm38)	missense	probably damaging	1.00
R5860:Dchs1	UTSW	7	105,772,035 (GRCm38)	missense	probably damaging	1.00
R5916:Dchs1	UTSW	7	105,759,166 (GRCm38)	missense	probably damaging	1.00
R5965:Dchs1	UTSW	7	105,755,925 (GRCm38)	missense	probably damaging	1.00
R5997:Dchs1	UTSW	7	105,754,095 (GRCm38)	missense	probably benign	0.08
R6065:Dchs1	UTSW	7	105,755,421 (GRCm38)	missense	probably damaging	1.00
R6136:Dchs1	UTSW	7	105,760,925 (GRCm38)	missense	probably benign
R6137:Dchs1	UTSW	7	105,765,106 (GRCm38)	missense	probably damaging	0.99
R6324:Dchs1	UTSW	7	105,764,938 (GRCm38)	missense	probably benign	0.05
R6363:Dchs1	UTSW	7	105,758,472 (GRCm38)	missense	probably benign	0.12
R6466:Dchs1	UTSW	7	105,764,541 (GRCm38)	missense	probably benign	0.09
R6544:Dchs1	UTSW	7	105,758,178 (GRCm38)	missense	probably damaging	1.00
R6572:Dchs1	UTSW	7	105,758,806 (GRCm38)	missense	possibly damaging	0.94
R6579:Dchs1	UTSW	7	105,762,913 (GRCm38)	missense	probably benign	0.17
R6632:Dchs1	UTSW	7	105,761,878 (GRCm38)	missense	probably damaging	1.00
R6725:Dchs1	UTSW	7	105,758,793 (GRCm38)	missense	probably damaging	0.99
R6789:Dchs1	UTSW	7	105,757,003 (GRCm38)	missense	possibly damaging	0.61
R6868:Dchs1	UTSW	7	105,763,503 (GRCm38)	missense	possibly damaging	0.91
R7058:Dchs1	UTSW	7	105,757,021 (GRCm38)	missense	probably benign
R7064:Dchs1	UTSW	7	105,763,185 (GRCm38)	missense	probably damaging	0.99
R7076:Dchs1	UTSW	7	105,761,871 (GRCm38)	missense	probably benign	0.04
R7191:Dchs1	UTSW	7	105,765,439 (GRCm38)	missense	possibly damaging	0.89
R7298:Dchs1	UTSW	7	105,755,131 (GRCm38)	nonsense	probably null
R7380:Dchs1	UTSW	7	105,758,628 (GRCm38)	missense	probably benign	0.35
R7438:Dchs1	UTSW	7	105,754,948 (GRCm38)	missense	probably benign	0.30
R7496:Dchs1	UTSW	7	105,761,859 (GRCm38)	missense	probably damaging	1.00
R7534:Dchs1	UTSW	7	105,772,373 (GRCm38)	missense	probably benign	0.00
R7604:Dchs1	UTSW	7	105,765,982 (GRCm38)	missense	probably damaging	1.00
R7631:Dchs1	UTSW	7	105,759,238 (GRCm38)	missense	probably benign
R7821:Dchs1	UTSW	7	105,765,145 (GRCm38)	missense	probably benign	0.00
R7834:Dchs1	UTSW	7	105,765,567 (GRCm38)	missense	probably benign	0.39
R7841:Dchs1	UTSW	7	105,762,973 (GRCm38)	missense	probably benign
R7913:Dchs1	UTSW	7	105,759,228 (GRCm38)	missense	possibly damaging	0.61
R8041:Dchs1	UTSW	7	105,755,188 (GRCm38)	missense	probably benign	0.45
R8076:Dchs1	UTSW	7	105,761,982 (GRCm38)	missense	probably damaging	1.00
R8076:Dchs1	UTSW	7	105,755,921 (GRCm38)	missense	possibly damaging	0.52
R8087:Dchs1	UTSW	7	105,753,499 (GRCm38)	missense	probably benign	0.41
R8125:Dchs1	UTSW	7	105,764,882 (GRCm38)	missense	possibly damaging	0.91
R8223:Dchs1	UTSW	7	105,762,617 (GRCm38)	missense	possibly damaging	0.81
R8239:Dchs1	UTSW	7	105,765,511 (GRCm38)	missense	probably benign	0.22
R8476:Dchs1	UTSW	7	105,758,808 (GRCm38)	missense	probably benign	0.05
R8497:Dchs1	UTSW	7	105,758,961 (GRCm38)	missense	probably damaging	1.00
R8770:Dchs1	UTSW	7	105,771,738 (GRCm38)	missense	probably damaging	1.00
R8856:Dchs1	UTSW	7	105,760,857 (GRCm38)	missense	probably damaging	1.00
R8866:Dchs1	UTSW	7	105,755,390 (GRCm38)	missense	probably benign	0.00
R8948:Dchs1	UTSW	7	105,759,005 (GRCm38)	missense	probably benign	0.30
R8950:Dchs1	UTSW	7	105,759,005 (GRCm38)	missense	probably benign	0.30
R9029:Dchs1	UTSW	7	105,753,712 (GRCm38)	missense	probably benign	0.13
R9039:Dchs1	UTSW	7	105,756,008 (GRCm38)	missense	probably benign	0.11
R9081:Dchs1	UTSW	7	105,754,429 (GRCm38)	missense	probably benign	0.00
R9134:Dchs1	UTSW	7	105,755,703 (GRCm38)	missense	probably damaging	0.96
R9159:Dchs1	UTSW	7	105,765,919 (GRCm38)	missense	probably benign
R9162:Dchs1	UTSW	7	105,765,525 (GRCm38)	missense	probably damaging	1.00
R9169:Dchs1	UTSW	7	105,772,907 (GRCm38)	missense	probably damaging	1.00
R9262:Dchs1	UTSW	7	105,755,626 (GRCm38)	missense	probably damaging	1.00
R9292:Dchs1	UTSW	7	105,753,913 (GRCm38)	missense	probably damaging	1.00
R9325:Dchs1	UTSW	7	105,766,195 (GRCm38)	missense	possibly damaging	0.51
R9376:Dchs1	UTSW	7	105,765,774 (GRCm38)	critical splice donor site	probably null
R9392:Dchs1	UTSW	7	105,772,662 (GRCm38)	missense	probably benign	0.09
R9619:Dchs1	UTSW	7	105,764,455 (GRCm38)	missense	probably benign	0.07
R9680:Dchs1	UTSW	7	105,762,418 (GRCm38)	missense	probably damaging	1.00
R9687:Dchs1	UTSW	7	105,757,984 (GRCm38)	missense	probably damaging	0.99
R9747:Dchs1	UTSW	7	105,763,475 (GRCm38)	missense	probably damaging	1.00
Z1177:Dchs1	UTSW	7	105,757,693 (GRCm38)	missense	probably damaging	1.00
Z1177:Dchs1	UTSW	7	105,758,551 (GRCm38)	missense	probably benign	0.00

Posted On

2015-04-16