Incidental Mutation 'IGL02502:Gm1123'
ID296120
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm1123
Ensembl Gene ENSMUSG00000044860
Gene Namepredicted gene 1123
SynonymsLOC382097
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.126) question?
Stock #IGL02502
Quality Score
Status
Chromosome9
Chromosomal Location99006790-99035715 bp(-) (GRCm38)
Type of Mutationnonsense
DNA Base Change (assembly) A to T at 99009390 bp
ZygosityHeterozygous
Amino Acid Change Tyrosine to Stop codon at position 335 (Y335*)
Ref Sequence ENSEMBL: ENSMUSP00000076020 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000076730]
Predicted Effect probably null
Transcript: ENSMUST00000076730
AA Change: Y335*
SMART Domains Protein: ENSMUSP00000076020
Gene: ENSMUSG00000044860
AA Change: Y335*

DomainStartEndE-ValueType
low complexity region 3 10 N/A INTRINSIC
IGv 36 123 1.85e-7 SMART
IG 151 264 3.33e-9 SMART
IGv 286 373 6.02e-7 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 59 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Acoxl A G 2: 128,075,884 N216S probably damaging Het
Akap12 A G 10: 4,353,163 D96G probably damaging Het
Akna A G 4: 63,368,203 V1353A probably benign Het
Ambra1 A G 2: 91,900,532 D914G probably damaging Het
Ap1s3 A G 1: 79,623,722 V84A possibly damaging Het
Arhgef6 T C X: 57,280,263 E282G probably damaging Het
C2cd2 G T 16: 97,876,390 S378Y possibly damaging Het
Cd101 C A 3: 101,011,825 A654S probably damaging Het
Cep295 A C 9: 15,350,913 probably benign Het
Csn1s1 A G 5: 87,680,925 I283V probably benign Het
Cst3 A G 2: 148,875,145 probably benign Het
Cyp2b9 T C 7: 26,187,814 probably null Het
Dffb A G 4: 153,965,616 probably benign Het
Dnah10 A G 5: 124,821,287 Y3711C probably damaging Het
Eif4g2 T C 7: 111,081,541 S3G probably damaging Het
Erbb3 C T 10: 128,570,284 R1088H probably benign Het
Evpl T C 11: 116,222,718 D1382G probably damaging Het
Fam168a A G 7: 100,824,210 D102G probably damaging Het
Fbxo7 A G 10: 86,033,297 Y284C probably damaging Het
G6pd2 T C 5: 61,809,628 Y249H probably damaging Het
Gm5624 C T 14: 44,559,839 probably null Het
Hectd1 A T 12: 51,797,852 M536K possibly damaging Het
Ikbkg T A X: 74,443,827 V334E probably benign Het
Ipo7 T C 7: 110,051,050 L769P probably damaging Het
Jmjd1c A T 10: 67,225,861 K1331I probably benign Het
Krt32 T C 11: 100,087,923 K102E probably damaging Het
Lrrc34 A T 3: 30,645,245 N20K probably benign Het
Lrrc47 A G 4: 154,016,014 E349G probably benign Het
Mdn1 A G 4: 32,670,579 I415V possibly damaging Het
Myh10 A G 11: 68,814,372 probably null Het
Nbeal2 A G 9: 110,633,768 S1376P probably damaging Het
Nfx1 T C 4: 40,976,345 probably benign Het
Notch3 A T 17: 32,158,278 C246* probably null Het
Nr3c2 A G 8: 77,242,514 Y976C probably damaging Het
Olfr1484 A G 19: 13,585,748 Y105C probably damaging Het
Olfr503 T A 7: 108,544,639 M36K probably damaging Het
Olfr64 A G 7: 103,893,489 V82A probably damaging Het
P2rx7 C T 5: 122,680,987 R491C possibly damaging Het
Pdzd3 G A 9: 44,249,651 A206V probably benign Het
Phex T A X: 157,183,827 Y625F possibly damaging Het
Pkhd1 T C 1: 20,392,165 D2055G probably damaging Het
Pmm2 T C 16: 8,645,363 probably benign Het
Prdm15 T C 16: 97,839,339 D16G probably damaging Het
Prune2 T A 19: 17,123,881 C2250S probably benign Het
Rasgef1a T A 6: 118,080,482 F48Y probably benign Het
Rhoq T C 17: 86,963,649 V15A probably damaging Het
Rnf216 G A 5: 143,068,867 A585V probably damaging Het
Sept9 T A 11: 117,290,662 I96N probably damaging Het
Shprh T A 10: 11,194,357 D1492E possibly damaging Het
Slc22a26 A T 19: 7,790,760 probably null Het
Tek T G 4: 94,853,581 probably null Het
Tenm3 T C 8: 48,288,016 E782G probably damaging Het
Trmt5 A G 12: 73,281,227 C401R probably benign Het
Tspear T G 10: 77,852,958 probably benign Het
Ubr5 G A 15: 38,030,689 T414I probably benign Het
Vcl A T 14: 21,019,385 T710S probably damaging Het
Vmn2r25 A T 6: 123,839,433 D396E probably damaging Het
Wtip A G 7: 34,118,669 probably null Het
Zap70 A G 1: 36,778,806 probably benign Het
Other mutations in Gm1123
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01759:Gm1123 APN 9 99023254 missense probably benign
R0091:Gm1123 UTSW 9 99023352 missense possibly damaging 0.80
R4628:Gm1123 UTSW 9 99014236 missense probably damaging 0.98
R4668:Gm1123 UTSW 9 99009373 missense probably damaging 1.00
R4754:Gm1123 UTSW 9 99023240 splice site probably null
R4754:Gm1123 UTSW 9 99023241 critical splice donor site probably null
R4778:Gm1123 UTSW 9 99018507 missense probably benign
R4840:Gm1123 UTSW 9 99018569 missense probably damaging 0.98
R4905:Gm1123 UTSW 9 99009316 missense probably benign 0.16
R5645:Gm1123 UTSW 9 99014191 missense probably benign 0.41
R5685:Gm1123 UTSW 9 99009433 critical splice acceptor site probably null
R7390:Gm1123 UTSW 9 99010980 missense probably benign 0.19
R7858:Gm1123 UTSW 9 99014054 missense possibly damaging 0.87
R8196:Gm1123 UTSW 9 99023256 missense probably benign
Posted On2015-04-16