Incidental Mutation 'IGL02506:Paqr9'
ID296310
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Paqr9
Ensembl Gene ENSMUSG00000064225
Gene Nameprogestin and adipoQ receptor family member IX
Synonyms1700020G04Rik
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.068) question?
Stock #IGL02506
Quality Score
Status
Chromosome9
Chromosomal Location95559657-95568023 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to C at 95560695 bp
ZygosityHeterozygous
Amino Acid Change Valine to Alanine at position 246 (V246A)
Ref Sequence ENSEMBL: ENSMUSP00000078547 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000079597]
Predicted Effect probably benign
Transcript: ENSMUST00000079597
AA Change: V246A

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000078547
Gene: ENSMUSG00000064225
AA Change: V246A

DomainStartEndE-ValueType
low complexity region 15 39 N/A INTRINSIC
Pfam:HlyIII 76 324 2.1e-35 PFAM
transmembrane domain 340 362 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000213295
Predicted Effect noncoding transcript
Transcript: ENSMUST00000217220
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 57 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abcg8 A G 17: 84,692,488 E189G possibly damaging Het
Acad11 T C 9: 104,091,732 probably null Het
Adcy7 G T 8: 88,317,943 R488L probably damaging Het
Akt1 C T 12: 112,659,280 probably benign Het
Ano9 C T 7: 141,102,254 probably benign Het
Arhgap15 A G 2: 44,063,808 D182G possibly damaging Het
Asxl3 T A 18: 22,452,399 V127D probably benign Het
Cacna1g A G 11: 94,429,129 M1407T probably damaging Het
Card9 A C 2: 26,354,415 probably benign Het
Cdh5 A G 8: 104,137,822 N472D probably damaging Het
Ceacam2 T A 7: 25,527,954 T343S probably benign Het
Cic T A 7: 25,290,857 C1928S probably benign Het
Clk3 C T 9: 57,754,644 W31* probably null Het
Cntn4 A G 6: 106,618,388 T489A probably benign Het
Crispld1 G A 1: 17,756,305 R431H probably damaging Het
Crmp1 T A 5: 37,278,855 probably benign Het
Cyld A G 8: 88,729,590 T423A possibly damaging Het
Cyp3a44 A T 5: 145,799,388 I84N probably damaging Het
D2hgdh A G 1: 93,829,785 N141D probably damaging Het
Dip2b T A 15: 100,157,281 L341Q probably damaging Het
F3 C T 3: 121,731,674 T53I possibly damaging Het
Fam227b T A 2: 126,003,911 Y386F probably benign Het
Fmn1 A T 2: 113,525,295 T694S unknown Het
Gcnt2 T A 13: 40,887,380 V5E probably benign Het
Herpud1 G T 8: 94,394,642 E355* probably null Het
Igf1r T C 7: 68,193,396 S752P probably benign Het
Iqsec1 T C 6: 90,672,075 I687V possibly damaging Het
Kdm5a T C 6: 120,432,149 S1598P probably damaging Het
Klk9 A G 7: 43,795,639 E185G probably benign Het
Myo16 G T 8: 10,390,217 R423L probably damaging Het
Myo7b T C 18: 31,967,154 E1609G probably damaging Het
Nom1 T A 5: 29,439,816 probably benign Het
Nomo1 A G 7: 46,078,056 I1040V possibly damaging Het
Olfr887 G A 9: 38,085,445 G203D probably damaging Het
Pfkfb4 A T 9: 109,030,336 D437V probably benign Het
Phldb1 G T 9: 44,710,926 D797E probably benign Het
Pkd1l3 A G 8: 109,647,500 E1399G probably damaging Het
Plekhs1 G A 19: 56,471,766 C97Y probably damaging Het
Plscr4 A T 9: 92,489,991 I272L possibly damaging Het
Prlhr A C 19: 60,467,928 Y67D probably damaging Het
Rab3gap2 A G 1: 185,252,024 probably benign Het
Rad23b T C 4: 55,382,511 V238A probably benign Het
Sel1l2 T C 2: 140,275,460 T164A possibly damaging Het
Serpinh1 T A 7: 99,346,992 K295M probably damaging Het
Slc45a4 T C 15: 73,581,838 E770G probably benign Het
Spag4 T C 2: 156,069,222 L390P probably damaging Het
Stip1 A G 19: 7,035,489 probably benign Het
Tacr1 A G 6: 82,403,758 N50S probably damaging Het
Tg T C 15: 66,741,594 V433A possibly damaging Het
Ubap1l T A 9: 65,369,211 probably benign Het
Usp40 A T 1: 87,982,016 I572K probably damaging Het
Vps13b G T 15: 35,917,162 E3717D probably damaging Het
Wdr81 T C 11: 75,444,406 N1778S probably benign Het
Ylpm1 T A 12: 85,049,191 F1162Y probably damaging Het
Zbtb10 T A 3: 9,265,237 F552I probably damaging Het
Zfp507 T C 7: 35,776,466 I811V probably damaging Het
Zfp663 A T 2: 165,353,951 V116D probably benign Het
Other mutations in Paqr9
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02601:Paqr9 APN 9 95560824 missense probably damaging 0.99
R0845:Paqr9 UTSW 9 95560740 missense probably damaging 1.00
R1553:Paqr9 UTSW 9 95560209 missense probably damaging 0.99
R2129:Paqr9 UTSW 9 95561069 missense probably benign
R2171:Paqr9 UTSW 9 95560878 missense probably damaging 0.99
R4118:Paqr9 UTSW 9 95560899 missense probably damaging 0.98
R4563:Paqr9 UTSW 9 95560944 missense probably benign 0.25
R4840:Paqr9 UTSW 9 95560670 missense probably damaging 0.98
R5202:Paqr9 UTSW 9 95560110 missense probably damaging 0.99
R6176:Paqr9 UTSW 9 95560775 missense possibly damaging 0.64
R6750:Paqr9 UTSW 9 95560997 missense probably damaging 0.99
R6885:Paqr9 UTSW 9 95560043 missense probably benign 0.00
R7247:Paqr9 UTSW 9 95560193 missense possibly damaging 0.95
R7719:Paqr9 UTSW 9 95560776 missense possibly damaging 0.90
R7954:Paqr9 UTSW 9 95560628 missense probably damaging 1.00
X0027:Paqr9 UTSW 9 95561016 missense probably damaging 1.00
Z1176:Paqr9 UTSW 9 95560306 missense possibly damaging 0.87
Posted On2015-04-16