Incidental Mutation 'IGL02519:Iqcf6'
ID296867
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Iqcf6
Ensembl Gene ENSMUSG00000091129
Gene NameIQ motif containing F6
Synonyms100041096
Accession Numbers
Is this an essential gene? Possibly non essential (E-score: 0.415) question?
Stock #IGL02519
Quality Score
Status
Chromosome9
Chromosomal Location106626582-106627675 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) C to T at 106627280 bp
ZygosityHeterozygous
Amino Acid Change Arginine to Cysteine at position 48 (R48C)
Ref Sequence ENSEMBL: ENSMUSP00000131823 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000171091]
Predicted Effect probably damaging
Transcript: ENSMUST00000171091
AA Change: R48C

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000131823
Gene: ENSMUSG00000091129
AA Change: R48C

DomainStartEndE-ValueType
IQ 35 57 2.06e-3 SMART
IQ 91 113 8.13e-2 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 41 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4932438A13Rik A G 3: 36,895,315 E370G probably damaging Het
Adamts13 A T 2: 26,978,675 I224F probably damaging Het
Adamts17 A G 7: 67,124,973 T947A possibly damaging Het
Ankfn1 T C 11: 89,405,678 E75G probably benign Het
Arfgef1 G T 1: 10,209,668 H225N probably benign Het
Arsi A G 18: 60,917,067 S341G probably damaging Het
Aspm T A 1: 139,461,927 probably benign Het
Cacna1i C T 15: 80,361,874 R490* probably null Het
Cd33 C T 7: 43,528,729 probably benign Het
Clmn T C 12: 104,791,853 I135V probably damaging Het
Crebbp A T 16: 4,101,593 N795K possibly damaging Het
Dhps A G 8: 85,073,299 D126G probably damaging Het
Dlg2 G T 7: 91,940,115 V196L possibly damaging Het
Dsg1c T A 18: 20,283,733 I897N probably damaging Het
Dzip3 A G 16: 48,928,396 L1059S probably damaging Het
Epha7 A T 4: 28,821,494 T220S possibly damaging Het
Fgf17 A G 14: 70,638,528 I88T probably damaging Het
G3bp2 A G 5: 92,066,524 V137A possibly damaging Het
Gnal G A 18: 67,088,765 E80K unknown Het
Hectd1 T G 12: 51,769,111 S1393R probably damaging Het
Igsf6 T C 7: 121,068,273 I173M possibly damaging Het
Il2ra A C 2: 11,683,090 E227A possibly damaging Het
Kdm3a G T 6: 71,611,586 Q480K probably benign Het
Larp4b C A 13: 9,158,580 A423E probably benign Het
Magea6 T C X: 154,924,745 D105G probably benign Het
Nop53 C A 7: 15,939,272 probably benign Het
Olfr307 A T 7: 86,335,581 F272I probably benign Het
Olfr338 T C 2: 36,377,313 L179P possibly damaging Het
Pgghg A G 7: 140,944,981 T352A possibly damaging Het
Setd2 T C 9: 110,553,116 S1464P probably damaging Het
Sspo C A 6: 48,484,828 T3609N probably damaging Het
Sulf1 T A 1: 12,838,363 Y533* probably null Het
Thsd7b A G 1: 129,613,195 S346G probably benign Het
Tmem161b T A 13: 84,294,744 L261Q probably damaging Het
Tmem63b T A 17: 45,665,208 T493S possibly damaging Het
Tmprss11d A T 5: 86,306,305 C214S probably damaging Het
Trim16 A T 11: 62,834,079 E144V possibly damaging Het
Unc13d T C 11: 116,070,533 Y356C probably damaging Het
Urgcp A T 11: 5,717,745 F198I probably benign Het
Vmn2r111 T C 17: 22,548,339 I726V possibly damaging Het
Zzz3 A T 3: 152,427,390 E28D probably damaging Het
Other mutations in Iqcf6
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01598:Iqcf6 APN 9 106627508 missense probably benign
IGL02006:Iqcf6 APN 9 106627311 missense probably benign 0.13
R0925:Iqcf6 UTSW 9 106627301 missense probably benign 0.00
R1493:Iqcf6 UTSW 9 106627442 missense probably benign 0.00
R4686:Iqcf6 UTSW 9 106627344 missense probably damaging 1.00
R6590:Iqcf6 UTSW 9 106627302 missense possibly damaging 0.83
R6690:Iqcf6 UTSW 9 106627302 missense possibly damaging 0.83
R7489:Iqcf6 UTSW 9 106627457 missense probably benign 0.25
Posted On2015-04-16