Incidental Mutation 'IGL02546:Zfp787'
ID297825
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Zfp787
Ensembl Gene ENSMUSG00000046792
Gene Namezinc finger protein 787
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.155) question?
Stock #IGL02546
Quality Score
Status
Chromosome7
Chromosomal Location6131491-6155997 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 6132298 bp
ZygosityHeterozygous
Amino Acid Change Isoleucine to Asparagine at position 318 (I318N)
Ref Sequence ENSEMBL: ENSMUSP00000092468 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000094870] [ENSMUST00000207315]
Predicted Effect probably damaging
Transcript: ENSMUST00000094870
AA Change: I318N

PolyPhen 2 Score 0.993 (Sensitivity: 0.70; Specificity: 0.97)
SMART Domains Protein: ENSMUSP00000092468
Gene: ENSMUSG00000046792
AA Change: I318N

DomainStartEndE-ValueType
low complexity region 41 65 N/A INTRINSIC
ZnF_C2H2 66 88 5.67e-5 SMART
ZnF_C2H2 94 116 9.58e-3 SMART
ZnF_C2H2 122 144 1.84e-4 SMART
ZnF_C2H2 150 172 1.3e-4 SMART
ZnF_C2H2 178 200 6.88e-4 SMART
low complexity region 245 277 N/A INTRINSIC
ZnF_C2H2 280 303 2.36e-2 SMART
ZnF_C2H2 317 339 4.72e-2 SMART
Predicted Effect probably benign
Transcript: ENSMUST00000207315
Predicted Effect noncoding transcript
Transcript: ENSMUST00000208973
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 45 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4930444G20Rik A T 10: 22,066,927 W385R probably damaging Het
A730017C20Rik T A 18: 59,072,275 M45K probably damaging Het
Akap6 G T 12: 52,880,738 V144L probably damaging Het
Carmil1 A T 13: 24,115,499 N347K probably damaging Het
Cyp4a32 A G 4: 115,611,323 Y334C probably damaging Het
Dmxl2 C A 9: 54,366,414 probably benign Het
Eps8 C T 6: 137,479,066 A806T probably benign Het
Evl A G 12: 108,648,419 N24S possibly damaging Het
Fbxo15 T C 18: 84,962,722 probably null Het
Gm14179 A T 11: 99,743,193 Het
Hepacam2 A G 6: 3,483,568 V147A possibly damaging Het
Jmjd1c C A 10: 67,225,336 P1156Q possibly damaging Het
Mab21l3 A T 3: 101,823,308 V205E probably damaging Het
Mad2l1 T C 6: 66,535,967 I28T probably damaging Het
Mroh9 T A 1: 163,080,576 I2F probably benign Het
Msr1 A T 8: 39,615,747 I302K probably benign Het
Msrb3 C T 10: 120,850,001 V80I possibly damaging Het
Ncf4 A G 15: 78,261,019 D269G probably damaging Het
Nsl1 T A 1: 191,071,201 H156Q probably benign Het
Nutm1 T C 2: 112,248,324 D1082G probably benign Het
Olfr812 T A 10: 129,842,547 D165V probably damaging Het
Olfr835 T A 9: 19,035,354 V77D possibly damaging Het
Orc4 T C 2: 48,917,284 I212V probably null Het
Pde6c A G 19: 38,140,040 I184V probably benign Het
Pfkfb3 A T 2: 11,488,778 F129Y probably damaging Het
Ppp3cb T C 14: 20,501,554 D493G probably benign Het
Psg29 A G 7: 17,208,782 Y236C probably damaging Het
Pzp C T 6: 128,494,699 probably benign Het
Sgf29 T A 7: 126,671,853 V180E probably damaging Het
Sh3bp4 A G 1: 89,143,544 probably benign Het
Slc39a2 A T 14: 51,895,163 T188S probably benign Het
Slc6a13 G T 6: 121,333,364 M327I probably benign Het
Slitrk6 T A 14: 110,749,794 H827L probably benign Het
Thumpd2 T G 17: 81,054,455 K114T probably benign Het
Tnfrsf19 A T 14: 60,973,538 C234S possibly damaging Het
Tns2 A G 15: 102,110,940 D446G probably damaging Het
Tpm4 A G 8: 72,144,703 E137G probably damaging Het
Ttn G A 2: 76,795,557 R13307C probably damaging Het
Ubqln3 A G 7: 104,142,518 S122P probably benign Het
Ubr5 T C 15: 38,008,747 D1080G probably benign Het
Ulk4 A T 9: 121,152,307 L886* probably null Het
Unc80 T C 1: 66,554,953 S1164P possibly damaging Het
Uspl1 T C 5: 149,204,304 V371A possibly damaging Het
Virma T C 4: 11,494,804 V35A probably damaging Het
Zfp518a G A 19: 40,914,617 G997R probably damaging Het
Other mutations in Zfp787
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02721:Zfp787 APN 7 6132464 unclassified probably null
cheater UTSW 7 6133040 missense possibly damaging 0.93
R0063:Zfp787 UTSW 7 6132323 unclassified probably null
R1415:Zfp787 UTSW 7 6132695 missense probably damaging 1.00
R1434:Zfp787 UTSW 7 6132235 missense probably damaging 0.98
R2042:Zfp787 UTSW 7 6132764 missense possibly damaging 0.72
R5657:Zfp787 UTSW 7 6133054 missense probably damaging 1.00
R5919:Zfp787 UTSW 7 6132835 missense probably damaging 0.98
R6306:Zfp787 UTSW 7 6132361 missense probably damaging 1.00
R7273:Zfp787 UTSW 7 6133040 missense possibly damaging 0.93
R7316:Zfp787 UTSW 7 6155524 unclassified probably benign
R7396:Zfp787 UTSW 7 6132107 makesense probably null
R7880:Zfp787 UTSW 7 6132191 missense probably benign 0.00
R7963:Zfp787 UTSW 7 6132191 missense probably benign 0.00
Z1177:Zfp787 UTSW 7 6132124 missense probably damaging 0.98
Posted On2015-04-16