Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02547:Tcerg1l'

297897

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Tcerg1l

Ensembl Gene

ENSMUSG00000091002

Gene Name

transcription elongation regulator 1-like

Synonyms

5730476P14Rik

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL02547

Quality Score

Status

Chromosome

Chromosomal Location

137810703-137999459 bp(-) (GRCm39)

Type of Mutation

critical splice donor site (1 bp from exon)

DNA Base Change (assembly)

C to T at 137850100 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000124476 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000160436]

AlphaFold

Q3B807

Predicted Effect

probably null
Transcript: ENSMUST00000160436

SMART Domains

Protein: ENSMUSP00000124476
Gene: ENSMUSG00000091002

Domain	Start	End	E-Value	Type
low complexity region	6	44	N/A	INTRINSIC
low complexity region	52	97	N/A	INTRINSIC
WW	146	178	2.11e1	SMART
low complexity region	235	249	N/A	INTRINSIC
WW	344	376	3.29e-4	SMART
low complexity region	402	415	N/A	INTRINSIC
FF	454	507	4.57e-12	SMART
FF	520	574	1.53e-4	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000161213

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 51 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Akap6	T	A	12: 53,187,479 (GRCm39)	L1631H	probably damaging	Het
Atf7ip	T	A	6: 136,580,274 (GRCm39)		probably benign	Het
Atp5po	A	T	16: 91,725,849 (GRCm39)	Y48N	probably damaging	Het
Birc6	T	G	17: 74,886,640 (GRCm39)	M656R	probably benign	Het
Camkk1	A	G	11: 72,929,259 (GRCm39)	R455G	probably benign	Het
Casr	A	T	16: 36,336,036 (GRCm39)	M91K	probably benign	Het
Ccdc28a	A	T	10: 18,089,894 (GRCm39)	V124D	possibly damaging	Het
Ccnh	T	C	13: 85,350,623 (GRCm39)		probably benign	Het
Cdc37	G	T	9: 21,051,262 (GRCm39)		probably benign	Het
Cdon	A	G	9: 35,389,950 (GRCm39)	D868G	probably damaging	Het
Cstdc3	A	T	16: 36,132,888 (GRCm39)		probably benign	Het
Cyp4f15	A	G	17: 32,919,229 (GRCm39)	R351G	probably benign	Het
Dclk3	T	C	9: 111,298,091 (GRCm39)	I545T	probably damaging	Het
Dock4	A	G	12: 40,787,478 (GRCm39)	M798V	probably benign	Het
Gas7	A	T	11: 67,556,261 (GRCm39)	Q200L	probably damaging	Het
Ica1	T	C	6: 8,670,691 (GRCm39)		probably null	Het
Idh3a	T	A	9: 54,499,679 (GRCm39)	V31D	probably benign	Het
Il3ra	A	T	14: 14,351,970 (GRCm38)	T247S	probably benign	Het
Itgb7	A	G	15: 102,126,945 (GRCm39)	C497R	probably damaging	Het
Itm2c	T	C	1: 85,834,182 (GRCm39)	Y166H	probably damaging	Het
Mphosph8	A	G	14: 56,909,941 (GRCm39)	D98G	probably damaging	Het
Mstn	A	T	1: 53,103,284 (GRCm39)	I207F	probably benign	Het
Muc15	A	G	2: 110,561,650 (GRCm39)	R29G	probably damaging	Het
Neb	T	A	2: 52,078,742 (GRCm39)	T142S	probably damaging	Het
Nipbl	G	A	15: 8,381,082 (GRCm39)	T570I	probably benign	Het
Nr5a2	T	A	1: 136,868,665 (GRCm39)	M196L	probably benign	Het
Nrp1	C	A	8: 129,219,512 (GRCm39)	F643L	probably benign	Het
Or52ad1	A	G	7: 102,995,451 (GRCm39)	F228S	probably damaging	Het
Or52z15	T	C	7: 103,331,973 (GRCm39)	I16T	probably benign	Het
Or5a3	A	T	19: 12,399,675 (GRCm39)	M1L	probably benign	Het
Or8h8	A	G	2: 86,753,372 (GRCm39)	F168S	probably damaging	Het
Osbpl9	C	T	4: 108,925,680 (GRCm39)	W446*	probably null	Het
Pced1a	T	C	2: 130,261,627 (GRCm39)	D342G	possibly damaging	Het
Pira13	T	C	7: 3,824,660 (GRCm39)	D573G	probably damaging	Het
Prkcd	C	A	14: 30,321,426 (GRCm39)	W555L	probably damaging	Het
Prpf31	T	C	7: 3,633,898 (GRCm39)	S78P	probably benign	Het
Psg27	T	C	7: 18,294,553 (GRCm39)	T285A	probably benign	Het
Retreg3	A	T	11: 100,997,204 (GRCm39)	L92*	probably null	Het
Rmdn1	A	G	4: 19,605,501 (GRCm39)	K282E	possibly damaging	Het
Septin8	G	T	11: 53,428,092 (GRCm39)	R302L	probably damaging	Het
Serpina3a	A	G	12: 104,082,802 (GRCm39)	I192V	probably damaging	Het
Sgce	T	C	6: 4,711,301 (GRCm39)		probably benign	Het
Slco1a8	A	T	6: 141,936,116 (GRCm39)	L323Q	probably damaging	Het
Spats1	A	T	17: 45,785,743 (GRCm39)		probably benign	Het
Ttn	A	G	2: 76,559,730 (GRCm39)	V21230A	probably damaging	Het
Ubxn11	A	C	4: 133,836,895 (GRCm39)	D41A	possibly damaging	Het
Vps13c	T	G	9: 67,815,301 (GRCm39)	I979S	possibly damaging	Het
Zc3h6	T	A	2: 128,857,531 (GRCm39)	H683Q	probably benign	Het
Zfp1007	C	T	5: 109,826,628 (GRCm39)		probably null	Het
Zfp518a	G	A	19: 40,903,061 (GRCm39)	G997R	probably damaging	Het
Zfp629	T	C	7: 127,210,846 (GRCm39)		probably null	Het

Other mutations in Tcerg1l

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00504:Tcerg1l	APN	7	137,811,533 (GRCm39)	missense	probably damaging	0.99
IGL01402:Tcerg1l	APN	7	137,861,568 (GRCm39)	missense	probably damaging	0.98
IGL01510:Tcerg1l	APN	7	137,996,034 (GRCm39)	splice site	probably benign
IGL01638:Tcerg1l	APN	7	137,881,805 (GRCm39)	missense	probably damaging	1.00
IGL01710:Tcerg1l	APN	7	137,996,789 (GRCm39)	missense	possibly damaging	0.81
IGL02887:Tcerg1l	APN	7	137,831,619 (GRCm39)	missense	probably damaging	1.00
IGL03105:Tcerg1l	APN	7	137,850,173 (GRCm39)	splice site	probably benign
IGL03348:Tcerg1l	APN	7	137,815,100 (GRCm39)	missense	probably damaging	0.97
R0378:Tcerg1l	UTSW	7	137,878,384 (GRCm39)	missense	probably benign	0.01
R1474:Tcerg1l	UTSW	7	137,881,804 (GRCm39)	missense	probably damaging	0.99
R1589:Tcerg1l	UTSW	7	137,963,496 (GRCm39)	missense	probably damaging	0.99
R1658:Tcerg1l	UTSW	7	137,995,909 (GRCm39)	missense	probably damaging	0.98
R1792:Tcerg1l	UTSW	7	137,963,595 (GRCm39)	missense	probably benign	0.07
R1807:Tcerg1l	UTSW	7	137,996,826 (GRCm39)	missense	probably benign	0.34
R2920:Tcerg1l	UTSW	7	137,850,108 (GRCm39)	missense	probably damaging	0.99
R3148:Tcerg1l	UTSW	7	137,861,596 (GRCm39)	missense	probably benign
R4106:Tcerg1l	UTSW	7	137,861,673 (GRCm39)	missense	probably damaging	0.99
R4180:Tcerg1l	UTSW	7	137,878,405 (GRCm39)	critical splice acceptor site	probably null
R4241:Tcerg1l	UTSW	7	137,999,361 (GRCm39)	missense	unknown
R4898:Tcerg1l	UTSW	7	137,819,786 (GRCm39)	missense	probably damaging	0.99
R5652:Tcerg1l	UTSW	7	137,881,775 (GRCm39)	missense	probably damaging	0.97
R6646:Tcerg1l	UTSW	7	137,996,912 (GRCm39)	splice site	probably null
R6824:Tcerg1l	UTSW	7	137,995,844 (GRCm39)	critical splice donor site	probably null
R7414:Tcerg1l	UTSW	7	137,819,786 (GRCm39)	missense	probably damaging	0.97
R7490:Tcerg1l	UTSW	7	137,861,557 (GRCm39)	missense	probably damaging	1.00
R8810:Tcerg1l	UTSW	7	137,811,526 (GRCm39)	missense	possibly damaging	0.79
R8889:Tcerg1l	UTSW	7	137,999,260 (GRCm39)	nonsense	probably null
R8892:Tcerg1l	UTSW	7	137,999,260 (GRCm39)	nonsense	probably null
R9146:Tcerg1l	UTSW	7	137,831,588 (GRCm39)	missense	probably damaging	1.00
R9374:Tcerg1l	UTSW	7	137,995,998 (GRCm39)	missense	possibly damaging	0.95
R9392:Tcerg1l	UTSW	7	137,815,164 (GRCm39)	missense	probably damaging	0.98
R9402:Tcerg1l	UTSW	7	137,811,551 (GRCm39)	missense	probably damaging	0.99
R9428:Tcerg1l	UTSW	7	137,811,490 (GRCm39)	missense	probably damaging	0.99
R9551:Tcerg1l	UTSW	7	137,995,998 (GRCm39)	missense	possibly damaging	0.95
R9552:Tcerg1l	UTSW	7	137,995,998 (GRCm39)	missense	possibly damaging	0.95
R9572:Tcerg1l	UTSW	7	137,881,787 (GRCm39)	missense	probably benign	0.07
R9624:Tcerg1l	UTSW	7	137,995,923 (GRCm39)	missense	possibly damaging	0.71

Posted On

2015-04-16