Incidental Mutation 'IGL02550:Gm7361'
ID297999
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm7361
Ensembl Gene ENSMUSG00000059645
Gene Namepredicted gene 7361
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.100) question?
Stock #IGL02550
Quality Score
Status
Chromosome5
Chromosomal Location26257691-26264308 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 26261122 bp
ZygosityHeterozygous
Amino Acid Change Isoleucine to Valine at position 161 (I161V)
Ref Sequence ENSEMBL: ENSMUSP00000073781 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000074148]
Predicted Effect possibly damaging
Transcript: ENSMUST00000074148
AA Change: I161V

PolyPhen 2 Score 0.785 (Sensitivity: 0.85; Specificity: 0.93)
SMART Domains Protein: ENSMUSP00000073781
Gene: ENSMUSG00000059645
AA Change: I161V

DomainStartEndE-ValueType
Pfam:Takusan 50 134 2.1e-26 PFAM
low complexity region 154 168 N/A INTRINSIC
low complexity region 235 259 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 65 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2010109I03Rik T G 15: 74,880,755 H24P probably damaging Het
Acadl A G 1: 66,845,166 probably null Het
Acer3 G A 7: 98,223,978 T171I probably benign Het
Acsm2 C T 7: 119,573,284 P117S probably damaging Het
Anxa2 A G 9: 69,467,306 S22G probably benign Het
Arrb2 T C 11: 70,436,870 I120T probably damaging Het
Atp11a G T 8: 12,816,997 K141N possibly damaging Het
Casd1 T C 6: 4,642,009 V762A probably benign Het
Ccdc61 A T 7: 18,893,302 S48T probably benign Het
Cntn2 T C 1: 132,529,063 M82V probably null Het
Cobll1 A G 2: 65,107,863 S359P probably damaging Het
Ctnnbl1 C A 2: 157,884,135 D465E probably benign Het
Def6 A T 17: 28,228,261 E622V probably benign Het
Dmgdh T C 13: 93,717,575 Y678H probably damaging Het
Dock9 A T 14: 121,698,312 M1K probably null Het
Esyt1 T C 10: 128,522,093 K216E probably damaging Het
Fhod3 A G 18: 25,022,960 D545G probably benign Het
Galnt12 A T 4: 47,104,126 D128V possibly damaging Het
Gm1110 C T 9: 26,881,834 V549I probably benign Het
Gm1966 A T 7: 106,601,639 noncoding transcript Het
Gsn T C 2: 35,282,607 probably benign Het
Il16 T A 7: 83,674,496 Q282L possibly damaging Het
Il3ra A G 14: 14,348,055 D67G probably benign Het
Insrr T C 3: 87,804,498 L515P probably damaging Het
Jhy A G 9: 40,917,170 F480S probably benign Het
Klc4 C A 17: 46,636,910 probably null Het
Klhl12 G T 1: 134,467,705 C135F possibly damaging Het
Mboat7 G T 7: 3,683,906 probably null Het
Myo1f A G 17: 33,580,150 probably benign Het
Myo1f G A 17: 33,588,142 D522N probably damaging Het
Nbea C A 3: 56,019,414 M789I probably damaging Het
Ncapd2 T C 6: 125,177,447 D602G probably benign Het
Ncaph2 A T 15: 89,369,861 K344* probably null Het
Nek2 A G 1: 191,822,259 Y70C probably damaging Het
Olfr1277 T A 2: 111,270,004 D121V probably damaging Het
Olfr1281 T C 2: 111,328,500 L27P probably damaging Het
Olfr31 T C 14: 14,328,423 L104P possibly damaging Het
Olfr857 C A 9: 19,713,047 F73L possibly damaging Het
Olfr955 T A 9: 39,470,546 Y60F probably benign Het
Olfr992 G A 2: 85,399,822 A237V probably damaging Het
Plcb3 T A 19: 6,960,176 K625* probably null Het
Plrg1 T C 3: 83,061,123 probably null Het
Ptpn12 A G 5: 20,998,139 V547A probably benign Het
Ralgapb A G 2: 158,448,411 D748G probably damaging Het
Rcbtb2 A G 14: 73,162,019 E41G probably damaging Het
Rela G T 19: 5,641,506 R236L possibly damaging Het
Rps6kc1 A G 1: 190,871,862 S188P probably damaging Het
Sipa1l1 A T 12: 82,440,949 K1666* probably null Het
Slco1a1 C T 6: 141,943,465 M40I probably benign Het
Smarca4 C A 9: 21,686,122 P1391Q probably benign Het
Stra6 A G 9: 58,150,083 N392S possibly damaging Het
Syt4 A G 18: 31,444,193 I36T probably damaging Het
Tgfbr2 A T 9: 116,110,129 M235K probably benign Het
Tmem87a T A 2: 120,374,485 probably null Het
Tmf1 T C 6: 97,158,561 D918G probably benign Het
Tnfaip2 A G 12: 111,446,101 Y312C probably damaging Het
Usp47 C T 7: 112,104,354 R1178C probably damaging Het
Vmn2r95 T A 17: 18,451,732 I577N probably damaging Het
Vps13b T C 15: 35,572,096 V953A probably benign Het
Wasl A G 6: 24,633,884 F127S probably damaging Het
Wdr1 C T 5: 38,540,863 V192I probably damaging Het
Wnt9a C T 11: 59,330,918 T214I probably damaging Het
Xpo5 A G 17: 46,229,329 D693G probably benign Het
Zan A G 5: 137,387,039 L5044P unknown Het
Zhx3 T C 2: 160,781,296 N317S probably damaging Het
Other mutations in Gm7361
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02447:Gm7361 APN 5 26257855 missense probably benign
R0011:Gm7361 UTSW 5 26258878 splice site probably benign
R0959:Gm7361 UTSW 5 26262053 missense possibly damaging 0.86
R1246:Gm7361 UTSW 5 26261227 nonsense probably null
R1580:Gm7361 UTSW 5 26257770 missense probably damaging 0.97
R1654:Gm7361 UTSW 5 26261099 missense probably damaging 0.99
R2065:Gm7361 UTSW 5 26262151 missense probably damaging 1.00
R4864:Gm7361 UTSW 5 26262010 critical splice acceptor site probably null
R5386:Gm7361 UTSW 5 26258905 missense probably benign
R6282:Gm7361 UTSW 5 26260413 missense probably benign 0.13
R6391:Gm7361 UTSW 5 26258962 missense probably benign 0.37
R6769:Gm7361 UTSW 5 26257769 nonsense probably null
R7205:Gm7361 UTSW 5 26261118 missense probably damaging 0.99
R7497:Gm7361 UTSW 5 26261190 missense probably benign
R7498:Gm7361 UTSW 5 26261190 missense probably benign
R7499:Gm7361 UTSW 5 26261190 missense probably benign
Z1177:Gm7361 UTSW 5 26261188 missense probably benign 0.01
Posted On2015-04-16